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Items: 1 to 20 of 72

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
USP24-dependent stabilization of Runx2 recruits a p300/NCOA3 complex to transactivate ADAMTS genes and promote degeneration of intervertebral disc in chronic inflammation mice
Xingguo Li, Jun Zhang, Bing Wang, Chao Chen, Enyu Zhang, Zhengpin Lv, Qicong He, Yaoquan Hu, Xuenan Wang, Fan Zhang
Biol Direct. 2023; 18: 37. Published online 2023 Jul 6. doi: 10.1186/s13062-023-00395-5
PMCID:
PMC10324278
AbstractArticlePDF–2.7M
3.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
4.
Prolonged XPO1 inhibition is essential for optimal antileukemic activity in NPM1-mutated AML
Giulia Pianigiani, Andrea Gagliardi, Federica Mezzasoma, Francesca Rocchio, Valentina Tini, Barbara Bigerna, Paolo Sportoletti, Simona Caruso, Andrea Marra, Sara Peruzzi, Eleonora Petito, Giulio Spinozzi, Sharon Shacham, Yosef Landesman, Concetta Quintarelli, Paolo Gresele, Franco Locatelli, Maria Paola Martelli, Brunangelo Falini, Lorenzo Brunetti
Blood Adv. 2022 Nov 22; 6(22): 5938–5949. Published online 2022 Aug 30. doi: 10.1182/bloodadvances.2022007563
PMCID:
PMC9701620
AbstractArticlePDF–2.2M
5.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
6.
Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells
Ane Olazagoitia-Garmendia, Linda Zhang, Paula Mera, Julie K Godbout, Maialen Sebastian-DelaCruz, Iraia Garcia-Santisteban, Luis Manuel Mendoza, Alain Huerta, Iñaki Irastorza, Govind Bhagat, Peter H Green, Laura Herrero, Dolors Serra, Jose Antonio Rodriguez, Elena F Verdu, Chuan He, Jose Ramon Bilbao, Ainara Castellanos-Rubio
Gut. 2022 Jan; 71(1): 68–76. Published online 2021 Feb 1. doi: 10.1136/gutjnl-2020-322566
PMCID:
PMC8666699
AbstractArticlePDF–2.1M
7.
Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain
Elisa Gorostieta-Salas, Daniel Moreno-Blas, Cristian Gerónimo-Olvera, Bulmaro Cisneros, Felipe A. Court, Susana Castro-Obregón
Oxid Med Cell Longev. 2021; 2021: 6682336. Published online 2021 Aug 13. doi: 10.1155/2021/6682336
PMCID:
PMC8382534
AbstractArticlePDF–7.1M
8.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
9.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
10.
Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia
Janek S. Walker, Zachary A. Hing, Bonnie Harrington, Jordan Baumhardt, Hatice Gulcin Ozer, Amy Lehman, Brian Giacopelli, Larry Beaver, Katie Williams, Jordan N. Skinner, Casey B. Cempre, Qingxiang Sun, Sharon Shacham, Benjamin R. Stromberg, Matthew K. Summers, Lynne V. Abruzzo, Laura Rassenti, Thomas J. Kipps, Sameer Parikh, Neil E. Kay, Kerry A. Rogers, Jennifer A. Woyach, Vincenzo Coppola, Yuh Min Chook, Christopher Oakes, John C. Byrd, Rosa Lapalombella
J Hematol Oncol. 2021; 14: 17. Published online 2021 Jan 15. doi: 10.1186/s13045-021-01032-2
PMCID:
PMC7809770
AbstractArticlePDF–11M
11.
NXF1 and CRM1 nuclear export pathways orchestrate nuclear export, translation and packaging of murine leukaemia retrovirus unspliced RNA
M. Mougel, C. Akkawi, C. Chamontin, J. Feuillard, L. Pessel-Vivares, M. Socol, S. Laine
RNA Biol. 2020; 17(4): 528–538. Published online 2020 Jan 23. doi: 10.1080/15476286.2020.1713539
PMCID:
PMC7237160
AbstractArticlePDF–3.3M
12.
Altered nuclear export signal recognition as a driver of oncogenesis
Justin Taylor, Maria Sendino, Alexander N. Gorelick, Alessandro Pastore, Matthew T. Chang, Alexander V. Penson, Elena I. Gavrila, Connor Stewart, Ella M. Melnik, Florisela Herrejon Chavez, Lillian Bitner, Akihide Yoshimi, Stanley Chun-wei Lee, Daichi Inoue, Bo Liu, Xiao J. Zhang, Anthony R. Mato, Ahmet Dogan, Michael G. Kharas, Yuhong Chen, Demin Wang, Rajesh K. Soni, Ronald C. Hendrickson, Gorka Prieto, Jose A. Rodriguez, Barry S. Taylor, Omar Abdel-Wahab
Cancer Discov. Author manuscript; available in PMC 2020 Apr 1.
Published in final edited form as: Cancer Discov. 2019 Oct; 9(10): 1452–1467. Published online 2019 Jul 8. doi: 10.1158/2159-8290.CD-19-0298
PMCID:
PMC6774834
AbstractArticlePDF–2.4M
13.
FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export
Brittany M. Edens, Caroline Vissers, Jing Su, Saravanan Arumugam, Zhaofa Xu, Han Shi, Nimrod Miller, Francisca Rojas Ringeling, Guo-li Ming, Chuan He, Hongjun Song, Yongchao C. Ma
Cell Rep. Author manuscript; available in PMC 2019 Aug 8.
Published in final edited form as: Cell Rep. 2019 Jul 23; 28(4): 845–854.e5. doi: 10.1016/j.celrep.2019.06.072
PMCID:
PMC6687293
AbstractArticlePDF–1.9M
14.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
15.
LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow
Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher
J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214
PMCID:
PMC6262777
AbstractArticle
16.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
17.
Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis
Seungtae Moon, Sun-Kyoung Im, Nackhyoung Kim, Hyesook Youn, Ui-Hyun Park, Joo-Yeon Kim, A.-Reum Kim, So-Jung An, Ji-Hoon Kim, Woong Sun, Jin-Taek Hwang, Eun-Joo Kim, Soo-Jong Um
Cell Death Dis. 2018 Nov; 9(11): 1118. Published online 2018 Nov 2. doi: 10.1038/s41419-018-1171-z
PMCID:
PMC6215009
AbstractArticlePDF–2.7M
18.
Combinatorial targeting of XPO1 and FLT3 exerts synergistic anti-leukemia effects through induction of differentiation and apoptosis in FLT3-mutated acute myeloid leukemias: from concept to clinical trial
Weiguo Zhang, Charlie Ly, Jo Ishizawa, Hong Mu, Vivian Ruvolo, Sharon Shacham, Naval Daver, Michael Andreeff
Haematologica. 2018 Oct; 103(10): 1642–1653. Prepublished online 2018 May 17. doi: 10.3324/haematol.2017.185082
PMCID:
PMC6165819
AbstractArticlePDF–3.1M
19.
Differential interaction between human and murine Crm1 and lentiviral Rev proteins
Yan Yue, Ayse K. Coskun, Navneet Jawanda, Jim Auer, Richard E. Sutton
Virology. Author manuscript; available in PMC 2018 Apr 24.
Published in final edited form as: Virology. 2018 Jan 1; 513: 1–10. Published online 2017 Oct 10. doi: 10.1016/j.virol.2017.09.027
PMCID:
PMC5914484
AbstractArticlePDF–1.5M
20.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M

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