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Select item 114854001.

Cellular prion protein acts as mediator of amyloid beta uptake by caveolin‐1 causing cellular dysfunctions in vitro and in vivo

Angela da Silva Correia, Matthias Schmitz, Anna‐Lisa Fischer, Susana da Silva Correia, Franco L. Simonetti, Gesine Saher, Roberto Goya‐Maldonado, Amandeep Singh Arora, Andre Fischer, Tiago F. Outeiro, Inga Zerr

Alzheimers Dement. 2024 Oct; 20(10): 6776–6792. Published online 2024 Aug 30. doi: 10.1002/alz.14120

PMCID:: PMC11485400

Abstract Article PDF–5.9M

Select item 114811822.

Creatine Promotes Endometriosis by Inducing Ferroptosis Resistance via Suppression of PrP

Siman Chen, Xiaoqian Ma, Yukai Liu, Zhiqi Zhong, Chunyan Wei, Mingqing Li, Xiaoyong Zhu

Adv Sci (Weinh) 2024 Oct; 11(38): 2403517. Published online 2024 Aug 9. doi: 10.1002/advs.202403517

PMCID:: PMC11481182

Abstract Article PDF–8.1M

Select item 114692993.

Copper binding alters the core structure of amyloid fibrils formed by Y145Stop human prion protein

Vidhyalakshmi Sridharan, Tara George, Daniel W. Conroy, Zach Shaffer, Witold K. Surewicz, Christopher P. Jaroniec

Phys Chem Chem Phys. 2024 Oct 23; 26(41): 26489–26496. Published online 2024 Oct 8. doi: 10.1039/d4cp03593c

PMCID:: PMC11469299

Abstract Article

Select item 113796264.

PrP^C controls epithelial-to-mesenchymal transition in EGFR-mutated NSCLC: implications for TKI resistance and patient follow-up

Claire Lailler, Audrey Didelot, Simon Garinet, Hugo Berthou, Marine Sroussi, Aurélien de Reyniès, Shoukat Dedhar, Séverine Martin-Lannerée, Elizabeth Fabre, Françoise Le Pimpec-Barthes, Alexandre Perrier, Virginie Poindessous, Audrey Mansuet-Lupo, Fatima Djouadi, Jean-Marie Launay, Pierre Laurent-Puig, Hélène Blons, Sophie Mouillet-Richard

Oncogene. 2024; 43(37): 2781–2794. Published online 2024 Aug 15. doi: 10.1038/s41388-024-03130-0

PMCID:: PMC11379626

Abstract Article PDF–5.3M

Select item 112977045.

Prion protein gene (PRNP) variation in German and Danish cervids

Sonja Ernst, Agata Piestrzyńska-Kajtoch, Jörn Gethmann, Małgorzata Natonek-Wiśniewska, Balal Sadeghi, Miroslaw P. Polak, Markus Keller, Dolores Gavier-Widén, Katayoun Moazami-Goudarzi, Fiona Houston, Martin H. Groschup, Christine Fast

Vet Res. 2024; 55: 98. Published online 2024 Aug 2. doi: 10.1186/s13567-024-01340-8

PMCID:: PMC11297704

Abstract Article PDF–4.1M

Select item 111461586.

Structural features of prions explored by sequence analysis. II. A PrP^Sc model

J.-P. Mornon, K. Prat, F. Dupuis, N. Boisset, I. Callebaut

Cell Mol Life Sci. 2002 Dec; 59(12): 2144–2154. doi: 10.1007/s000180200014

PMCID:: PMC11146158

Abstract Article PDF–623K

Select item 111314587.

The role of P-glycoprotein/cellular prion protein interaction in multidrug-resistant breast cancer cells treated with paclitaxel

Q.-Q. Li, X.-X. Cao, J.-D. Xu, Q. Chen, W.-J. Wang, F. Tang, Z.-Q. Chen, X.-P. Liu, Z.-D. Xu

Cell Mol Life Sci. 2009 Feb; 66(3): 504. Published online 2008 Dec 19. doi: 10.1007/s00018-008-8548-6

PMCID:: PMC11131458

Abstract Article PDF–3.7M

Select item 111147718.

Functional mechanisms of the cellular prion protein (PrP^C) associated anti-HIV-1 properties

Sandrine Alais, Ricardo Soto-Rifo, Vincent Balter, Henri Gruffat, Evelyne Manet, Laurent Schaeffer, Jean Luc Darlix, Andrea Cimarelli, Graça Raposo, Théophile Ohlmann, Pascal Leblanc

Cell Mol Life Sci. 2012 Apr; 69(8): 1331–1352. Published online 2011 Nov 11. doi: 10.1007/s00018-011-0879-z

PMCID:: PMC11114771

Abstract Article PDF–1.4M

Select item 110731709.

Cellular prion protein dysfunction in a prototypical inherited metabolic myopathy

Fatima-Zohra Boufroura, Céline Tomkiewicz-Raulet, Virginie Poindessous, Johan Castille, Jean-Luc Vilotte, Jean Bastin, Sophie Mouillet-Richard, Fatima Djouadi

Cell Mol Life Sci. 2021 Mar; 78(5): 2157–2167. Published online 2020 Sep 1. doi: 10.1007/s00018-020-03624-6

PMCID:: PMC11073170

Abstract Article PDF–8.4M

Select item 1093217510.

New Light on Prions: Putative Role of PrP^c in Pathophysiology of Mood Disorders

Adrian Andrzej Chrobak, Patrycja Pańczyszyn-Trzewik, Patrycja Król, Magdalena Pawelec-Bąk, Dominika Dudek, Marcin Siwek

Int J Mol Sci. 2024 Mar; 25(5): 2967. Published online 2024 Mar 4. doi: 10.3390/ijms25052967

PMCID:: PMC10932175

Abstract Article PDF–382K

Select item 1086314711.

Integrated transcriptomics uncovers an enhanced association between the prion protein gene expression and vesicle dynamics signatures in glioblastomas

Jacqueline Marcia Boccacino, Rafael dos Santos Peixoto, Camila Felix de Lima Fernandes, Giovanni Cangiano, Paula Rodrigues Sola, Bárbara Paranhos Coelho, Mariana Brandão Prado, Maria Isabel Melo-Escobar, Breno Pereira de Sousa, Shamini Ayyadhury, Gary D. Bader, Sueli Mieko Oba Shinjo, Suely Kazue Nagahashi Marie, Edroaldo Lummertz da Rocha, Marilene Hohmuth Lopes

BMC Cancer. 2024; 24: 199. Published online 2024 Feb 13. doi: 10.1186/s12885-024-11914-6

PMCID:: PMC10863147

Abstract Article PDF–5.2M

Select item 1079990312.

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun

Nat Commun. 2024; 15: 640. Published online 2024 Jan 20. doi: 10.1038/s41467-024-44958-0

PMCID:: PMC10799903

Abstract Article PDF–25M

Select item 1070937513.

Excess PrP^C inhibits muscle cell differentiation via miRNA-enhanced liquid–liquid phase separation implicated in myopathy

Jing Tao, Yanping Zeng, Bin Dai, Yin Liu, Xiaohan Pan, Li-Qiang Wang, Jie Chen, Yu Zhou, Zuneng Lu, Liwei Xie, Yi Liang

Nat Commun. 2023; 14: 8131. Published online 2023 Dec 8. doi: 10.1038/s41467-023-43826-7

PMCID:: PMC10709375

Abstract Article PDF–6.1M

Select item 1057353414.

Elevated E200K Somatic Mutation of the Prion Protein Gene (PRNP) in the Brain Tissues of Patients with Sporadic Creutzfeldt–Jakob Disease (CJD)

Sae-Young Won, Yong-Chan Kim, Byung-Hoon Jeong

Int J Mol Sci. 2023 Oct; 24(19): 14831. Published online 2023 Oct 2. doi: 10.3390/ijms241914831

PMCID:: PMC10573534

Abstract Article PDF–1.4M

Select item 1039973815.

Copper homeostasis-associated gene PRNP regulates ferroptosis and immune infiltration in breast cancer

Changwei Lin, Jiaqing He, Xiaopei Tong, Liying Song

PLoS One. 2023; 18(8): e0288091. Published online 2023 Aug 3. doi: 10.1371/journal.pone.0288091

PMCID:: PMC10399738

Abstract Article PDF–3.6M

Select item 1024315416.

Ring finger protein 12 activates AKT signalling to promote the progression of liver cancer by interacting with EGFR

Chengpeng Yu, Dean Rao, Tiantian Wang, Jiaqi Sheng, Enjun Lv, Long Zhang, Xun Lu, Jingjing Yu, Huifang Liang, Jia Song, Wenjie Huang

J Cell Mol Med. 2023 Jun; 27(11): 1523–1538. Published online 2023 May 2. doi: 10.1111/jcmm.17757

PMCID:: PMC10243154

Abstract Article PDF–51M

Select item 1023742217.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1016646318.

A novel subtype of sporadic Creutzfeldt–Jakob disease with PRNP codon 129MM genotype and PrP plaques

Rabeah Bayazid, Christina Orru’, Rabail Aslam, Yvonne Cohen, Amelia Silva-Rohwer, Seong-Ki Lee, Rossana Occhipinti, Qingzhong Kong, Shashirekha Shetty, Mark L. Cohen, Byron Caughey, Lawrence B. Schonberger, Brian S. Appleby, Ignazio Cali

Acta Neuropathol. 2023; 146(1): 121–143. Published online 2023 May 8. doi: 10.1007/s00401-023-02581-1

Correction in:: Acta Neuropathol. 2023; 146(1): 167–170.

PMCID:: PMC10166463

Abstract Article PDF–4.3M

Select item 1010924919.

PRNP expression predicts imaging findings in sporadic Creutzfeldt‐Jakob disease

Iris J. Broce, Eduardo Caverzasi, Simone Sacco, Ryan Michael Nillo, Matteo Paoletti, Rahul S. Desikan, Michael Geschwind, Leo P. Sugrue

Ann Clin Transl Neurol. 2023 Apr; 10(4): 536–552. Published online 2023 Feb 6. doi: 10.1002/acn3.51739

PMCID:: PMC10109249

Abstract Article PDF–3.4M

Select item 973704520.

Systematic Review of Clinical and Pathophysiological Features of Genetic Creutzfeldt–Jakob Disease Caused by a Val-to-Ile Mutation at Codon 180 in the Prion Protein Gene

Taiki Matsubayashi, Nobuo Sanjo

Int J Mol Sci. 2022 Dec; 23(23): 15172. Published online 2022 Dec 2. doi: 10.3390/ijms232315172

PMCID:: PMC9737045

Abstract Article PDF–1.5M

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