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Items: 1 to 20 of 38

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Non‐SMC condensin I complex subunit H participates in anti‐programmed cell death‐1 resistance of clear cell renal cell carcinomas
Zhi Chen, Weiqiang Ruan, Chunhao Guo, Ke Chen, Le Li, Jihua Tian, Zhiquan Hu, Dan Peng, Xing Zeng
Cell Prolif. 2023 Jul; 56(7): e13400. Published online 2023 Jan 15. doi: 10.1111/cpr.13400
PMCID:
PMC10334267
AbstractArticlePDF–6.7M
3.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
4.
Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons
Lewis Macdonald, Gillian C Taylor, Jennifer Margaret Brisbane, Ersi Christodoulou, Lucy Scott, Alex von Kriegsheim, Janet Rossant, Bin Gu, Andrew J Wood
eLife. 2022; 11: e77987. Published online 2022 Jun 23. doi: 10.7554/eLife.77987
PMCID:
PMC9273210
AbstractArticlePDF–1.8M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
The sperm associated antigen 6 interactome and its role in spermatogenesis
Yunhao Liu, Ling Zhang, Wei Li, Yuhong Li, Junpin Liu, Shiyang Zhang, Guanglun Pin, Shizhen Song, Pierre F Ray, Christophe Arnoult, Chunghee Cho, Balbina Garcia-Reyes, Uwe Knippschild, Jerome F. Strauss, III, Zhibing Zhang
Reproduction. Author manuscript; available in PMC 2020 Jul 18.
Published in final edited form as: Reproduction. 2019 Aug; 158(2): 181–197. doi: 10.1530/REP-18-0522
PMCID:
PMC7368494
AbstractArticlePDF–1.8M
8.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
9.
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis
Torben Mentrup, Kosta Theodorou, Florencia Cabrera-Cabrera, Andreas O. Helbig, Kathrin Happ, Marion Gijbels, Ann-Christine Gradtke, Björn Rabe, Akio Fukumori, Harald Steiner, Andreas Tholey, Regina Fluhrer, Marjo Donners, Bernd Schröder
J Exp Med. 2019 Apr 1; 216(4): 807–830. Published online 2019 Feb 28. doi: 10.1084/jem.20171438
PMCID:
PMC6446863
AbstractArticlePDF–6.1M
10.
Signal Peptide Peptidase‐Like 2c (SPPL2c) impairs vesicular transport and cleavage of SNARE proteins
Alkmini A Papadopoulou, Stephan A Müller, Torben Mentrup, Merav D Shmueli, Johannes Niemeyer, Martina Haug‐Kröper, Julia von Blume, Artur Mayerhofer, Regina Feederle, Bernd Schröder, Stefan F Lichtenthaler, Regina Fluhrer
EMBO Rep. 2019 Mar; 20(3): e46451. Published online 2019 Feb 7. doi: 10.15252/embr.201846451
Correction in:
EMBO Rep. 2019 May; 20(5): e48133.
PMCID:
PMC6399617
AbstractArticlePDF–8.6M
11.
Disruption of an anti-mycobacterial circuit between dendritic and Th cells in human SPPL2a deficiency
Xiao-Fei Kong, Ruben Martinez-Barricarte, James Kennedy, Federico Mele, Tomi Lazarov, Elissa K Deenick, Cindy S Ma, Gaëlle Breton, Kimberly B Lucero, David Langlais, Aziz Bousfiha, Caner Aytekin, Janet Markle, Céline Trouillet, Fabienne Jabot-Hanin, Cecilia S. Lindestam Arlehamn, Geetha Rao, Capucine Picard, Théo Lasseau, Daniela Latorre, Sophie Hambleton, Caroline Deswarte, Yuval Itan, Katia Abarca, Dewton Moraes-Vasconcelos, Fatima Ailal, Aydan Ikinciogullari, Figen Dogu, Ibtihal Benhsaien, Alessandro Sette, Laurent Abel, Stéphanie Boisson-Dupuis, Bernd Schröder, Michel C. Nussenzweig, Kang Liu, Frédéric Geissmann, Stuart G. Tangye, Philippe Gros, Federica Sallusto, Jacinta Bustamante, Jean-Laurent Casanova
Nat Immunol. Author manuscript; available in PMC 2019 Feb 20.
Published in final edited form as: Nat Immunol. 2018 Sep; 19(9): 973–985. Published online 2018 Aug 20. doi: 10.1038/s41590-018-0178-z
PMCID:
PMC6130844
AbstractArticlePDF–3.1M
12.
Repression of interstitial identity in nephron progenitor cells by Pax2 establishes the nephron-interstitium boundary throughout kidney development
Natalie Naiman, Kaoru Fujioka, Mari Fujino, M. Todd Valerius, S. Steven Potter, Andrew P. McMahon, Akio Kobayashi
Dev Cell. Author manuscript; available in PMC 2018 May 22.
Published in final edited form as: Dev Cell. 2017 May 22; 41(4): 349–365.e3. doi: 10.1016/j.devcel.2017.04.022
PMCID:
PMC5532731
AbstractArticlePDF–1.9M
13.
Condensin confers the longitudinal rigidity of chromosomes
Martin Houlard, Jonathan Godwin, Jean Metson, Jibak Lee, Tatsuya Hirano, Kim Nasmyth
Nat Cell Biol. Author manuscript; available in PMC 2017 Jan 3.
Published in final edited form as: Nat Cell Biol. 2015 Jun; 17(6): 771–781. Published online 2015 May 11. doi: 10.1038/ncb3167
PMCID:
PMC5207317
AbstractArticlePDF–2.7M
14.
The Interleukin-2-mTORc1 Axis Defines the Reciprocal Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells
John P. Ray, Matthew M. Staron, Justin A. Shyer, Ping-Chih Ho, Heather D. Marshall, Simon M. Gray, Brian J. Laidlaw, Koichi Araki, Rafi Ahmed, Susan M. Kaech, Joe Craft
Immunity. Author manuscript; available in PMC 2016 Oct 20.
Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 690–702. Published online 2015 Sep 22. doi: 10.1016/j.immuni.2015.08.017
PMCID:
PMC4618086
AbstractArticlePDF–2.2M
15.
Overlapping and Non-overlapping Functions of Condensins I and II in Neural Stem Cell Divisions
Kenji Nishide, Tatsuya Hirano
PLoS Genet. 2014 Dec; 10(12): e1004847. Published online 2014 Dec 4. doi: 10.1371/journal.pgen.1004847
PMCID:
PMC4256295
AbstractArticlePDF–2.4M
16.
Regulated Intramembrane Proteolysis of the Frontotemporal Lobar Degeneration Risk Factor, TMEM106B, by Signal Peptide Peptidase-like 2a (SPPL2a)
Owen A. Brady, Xiaolai Zhou, Fenghua Hu
J Biol Chem. 2014 Jul 11; 289(28): 19670–19680. Published online 2014 May 28. doi: 10.1074/jbc.M113.515700
PMCID:
PMC4094077
AbstractArticlePDF–2.2M
17.
The Intramembrane Proteases Signal Peptide Peptidase-Like 2a and 2b Have Distinct Functions In Vivo
Janna Schneppenheim, Susann Hüttl, Torben Mentrup, Renate Lüllmann-Rauch, Michelle Rothaug, Michael Engelke, Kai Dittmann, Ralf Dressel, Masatake Araki, Kimi Araki, Jürgen Wienands, Regina Fluhrer, Paul Saftig, Bernd Schröder
Mol Cell Biol. 2014 Apr; 34(8): 1398–1411. doi: 10.1128/MCB.00038-14
PMCID:
PMC3993588
AbstractArticlePDF–4.2M
18.
YY1 controls Igκ repertoire and B-cell development, and localizes with condensin on the Igκ locus
Xuan Pan, Madhusudhan Papasani, Yi Hao, Marco Calamito, Fang Wei, William J Quinn III, Arindam Basu, Junwen Wang, Suchita Hodawadekar, Kristina Zaprazna, Huifei Liu, Yang Shi, David Allman, Michael Cancro, Michael L Atchison
EMBO J. 2013 Apr 17; 32(8): 1168–1182. Published online 2013 Mar 26. doi: 10.1038/emboj.2013.66
PMCID:
PMC3630362
AbstractArticlePDF–2.7M
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain
Daniel R. Beisner, Petra Langerak, Albert E. Parker, Carol Dahlberg, Francella J. Otero, Sue E. Sutton, Laurent Poirot, Whitney Barnes, Michael A. Young, Sherry Niessen, Tim Wiltshire, Ursula Bodendorf, Bruno Martoglio, Benjamin Cravatt, Michael P. Cooke
J Exp Med. 2013 Jan 14; 210(1): 23–30. doi: 10.1084/jem.20121072
PMCID:
PMC3549714
AbstractArticlePDF–1.7M

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