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Items: 1 to 20 of 41

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The interaction of Synapsin 2a and Synaptogyrin-3 regulates fear extinction in mice
Xi-Ya Shen, Juan Zhang, He-Zhou Huang, Shao-Dan Li, Ling Zhou, Shi-Ping Wu, Cheng Tang, Xian Huang, Zhi-Qiang Liu, Zi-Yuan Guo, Xiang Li, Heng-Ye Man, You-Ming Lu, Ling-Qiang Zhu, Dan Liu
J Clin Invest. 2024 Feb 15; 134(4): e172802. Published online 2024 Jan 4. doi: 10.1172/JCI172802
PMCID:
PMC10866652
AbstractArticlePDF–4.1M
3.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
4.
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes
Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x
PMCID:
PMC9938216
AbstractArticlePDF–5.3M
5.
In vivo overexpression of synaptogyrin‐3 promotes striatal synaptic dopamine uptake in LRRK2R1441G mutant mouse model of Parkinson's disease
Philip Wing‐Lok Ho, Lingfei Li, Hui‐Fang Liu, Zoe Yuen‐Kiu Choi, Eunice Eun Seo Chang, Shirley Yin‐Yu Pang, Yasine Malki, Chi‐Ting Leung, Michelle Hiu‐Wai Kung, David Boyer Ramsden, Shu‐Leong Ho
Brain Behav. 2023 Feb; 13(2): e2886. Published online 2023 Jan 9. doi: 10.1002/brb3.2886
PMCID:
PMC9927849
AbstractArticlePDF–4.4M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8
Hsiang-Chun Chang, Jason Solomon Shapiro, Xinghang Jiang, Grant Senyei, Teruki Sato, Justin Geier, Konrad T Sawicki, Hossein Ardehali
eLife. 2021; 10: e65158. Published online 2021 Apr 9. doi: 10.7554/eLife.65158
PMCID:
PMC8055271
AbstractArticlePDF–2.8M
8.
Hepatic deficiency of augmenter of liver regeneration predisposes to nonalcoholic steatohepatitis and fibrosis
Sudhir Kumar, Alok K. Verma, Richa Rani, Akanksha Sharma, Jiang Wang, Shimul A. Shah, Jaideep Behari, Rosa Salazar Gonzalez, Rohit Kohli, Chandrashekhar R. Gandhi
Hepatology. Author manuscript; available in PMC 2021 Nov 1.
Published in final edited form as: Hepatology. 2020 Nov; 72(5): 1586–1604. Published online 2020 Oct 22. doi: 10.1002/hep.31167
PMCID:
PMC8025692
AbstractArticlePDF–1.5M
9.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
10.
Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation
Pablo Largo-Barrientos, Nuno Apóstolo, Eline Creemers, Zsuzsanna Callaerts-Vegh, Jef Swerts, Caitlin Davies, Joseph McInnes, Keimpe Wierda, Bart De Strooper, Tara Spires-Jones, Joris de Wit, Valerie Uytterhoeven, Patrik Verstreken
Neuron. 2021 Mar 3; 109(5): 767–777.e5. doi: 10.1016/j.neuron.2020.12.016
PMCID:
PMC7927913
AbstractArticle
11.
Tuning of Glutamate, But Not GABA, Release by an Intrasynaptic Vesicle APP Domain Whose Function Can Be Modulated by β- or α-Secretase Cleavage
Wen Yao, Marc D. Tambini, Xinran Liu, Luciano D'Adamio
J Neurosci. 2019 Aug 28; 39(35): 6992–7005. doi: 10.1523/JNEUROSCI.0207-19.2019
PMCID:
PMC6733572
AbstractArticlePDF–2.9M
12.
Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts
Mathan K Raja, Julia Preobraschenski, Sergio Del Olmo-Cabrera, Rebeca Martinez-Turrillas, Reinhard Jahn, Isabel Perez-Otano, John F Wesseling
eLife. 2019; 8: e40744. Published online 2019 May 15. doi: 10.7554/eLife.40744
PMCID:
PMC6519982
AbstractArticlePDF–1.5M
13.
Augmenter of liver regeneration protein deficiency promotes hepatic steatosis by inducing oxidative stress and microRNA-540 expression
Sudhir Kumar, Richa Rani, Rebekah Karns, Chandrashekhar R. Gandhi
FASEB J. 2019 Mar; 33(3): 3825–3840. Published online 2018 Dec 12. doi: 10.1096/fj.201802015R
PMCID:
PMC6404588
AbstractArticle
14.
RNA binding proteins co-localize with small tau inclusions in tauopathy
Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz da Rocha, Cheng Zhang, Wai Haung Yu, John Leszyk, Jose F. Abisambra, Hu Li, Benjamin Wolozin
Acta Neuropathol Commun. 2018; 6: 71. Published online 2018 Aug 1. doi: 10.1186/s40478-018-0574-5
PMCID:
PMC6069705
AbstractArticlePDF–5.5M
15.
The mitochondrial oxidoreductase CHCHD4 is present in a semi-oxidized state in vivo
Alican J. Erdogan, Muna Ali, Markus Habich, Silja L. Salscheider, Laura Schu, Carmelina Petrungaro, Luke W. Thomas, Margaret Ashcroft, Lars I. Leichert, Leticia Prates Roma, Jan Riemer
Redox Biol. 2018 Jul; 17: 200–206. Published online 2018 Mar 24. doi: 10.1016/j.redox.2018.03.014
PMCID:
PMC6007816
AbstractArticlePDF–1.6M
16.
ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance
Corneliu Sima, Eduardo Montero, Daniel Nguyen, Marcelo Freire, Paul Norris, Charles N. Serhan, Thomas E. Van Dyke
Sci Rep. 2017; 7: 12848. Published online 2017 Oct 9. doi: 10.1038/s41598-017-13185-7
Correction in:
Sci Rep. 2018; 8: 4143.
PMCID:
PMC5634420
AbstractArticlePDF–7.1M
17.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
18.
Liver-specific Deletion of Augmenter of Liver Regeneration Accelerates Development of Steatohepatitis and Hepatocellular Carcinoma in Mice
Chandrashekhar R. Gandhi, J. Richard Chaillet, Michael A. Nalesnik, Sudhir Kumar, Anil Dangi, A. Jake Demetris, Robert Ferrell, Tong Wu, Senad Divanovic, Traci Stankeiwicz, Benjamin Shaffer, Donna B. Stolz, Stephen A.K. Harvey, Jiang Wang, Thomas E. Starzl
Gastroenterology. Author manuscript; available in PMC 2016 Mar 22.
Published in final edited form as: Gastroenterology. 2015 Feb; 148(2): 379–391.e4. Published online 2014 Oct 13. doi: 10.1053/j.gastro.2014.10.008
PMCID:
PMC4802363
AbstractArticlePDF–1.1M
19.
Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice
Sudhir Kumar, Jiang Wang, Richa Rani, Chandrashekhar R. Gandhi
PLoS One. 2016; 11(1): e0147864. Published online 2016 Jan 25. doi: 10.1371/journal.pone.0147864
PMCID:
PMC4726524
AbstractArticlePDF–4.4M
20.
Deletion of Olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice
Afia Sultana, Naoki Nakaya, Lijin Dong, Mones Abu-Asab, Haohua Qian, Stanislav I. Tomarev
Exp Neurol. Author manuscript; available in PMC 2015 Nov 1.
Published in final edited form as: Exp Neurol. 2014 Nov; 0: 802–811. Published online 2014 Sep 10. doi: 10.1016/j.expneurol.2014.09.002
PMCID:
PMC4194240
AbstractArticlePDF–1.8M

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