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Items: 1 to 20 of 45

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
GPAT1 Deficiency in Mice Modulates NASH Progression in a Model-Dependent Manner
Kathleen R. Smith, Wenshan Wang, Melissa R. Miller, Magalie Boucher, Jessica E. Reynold, Natalie A. Daurio, Dongmei Li, Dinesh Hirenallur-Shanthappa, Youngwook Ahn, David A. Beebe, Kenneth L. Kelly, Trenton T. Ross, Kendra K. Bence, Min Wan
Cell Mol Gastroenterol Hepatol. 2024; 17(2): 279–291. Published online 2023 Oct 14. doi: 10.1016/j.jcmgh.2023.10.002
PMCID:
PMC10829521
AbstractArticlePDF–5.0M
3.
miR-195b is required for proper cellular homeostasis in the elderly
Maria del Mar Muñoz-Gallardo, Carlos Garcia-Padilla, Cristina Vicente-Garcia, Jaime Carvajal, Amelia Arenega, Diego Franco
Sci Rep. 2024; 14: 810. Published online 2024 Jan 8. doi: 10.1038/s41598-024-51256-8
PMCID:
PMC10774362
AbstractArticlePDF–3.7M
4.
Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease
Zixi Wang, Shijia Zhu, Yuemeng Jia, Yunguan Wang, Naoto Kubota, Naoto Fujiwara, Ruth Gordillo, Cheryl Lewis, Min Zhu, Tripti Sharma, Lin Li, Qiyu Zeng, Yu-Hsuan Lin, Meng-Hsiung Hsieh, Purva Gopal, Tao Wang, Matt Hoare, Peter Campbell, Yujin Hoshida, Hao Zhu
Cell. Author manuscript; available in PMC 2024 Apr 27.
Published in final edited form as: Cell. 2023 Apr 27; 186(9): 1968–1984.e20. Published online 2023 Apr 10. doi: 10.1016/j.cell.2023.03.014
PMCID:
PMC10321862
AbstractArticlePDF–4.6M
5.
The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation
Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang
Mol Metab. 2022 Oct; 64: 101548. Published online 2022 Jul 19. doi: 10.1016/j.molmet.2022.101548
PMCID:
PMC9386464
AbstractArticlePDF–6.6M
6.
Bardet–Biedl Syndrome ciliopathy is linked to altered hematopoiesis and dysregulated self‐tolerance
Oksana Tsyklauri, Veronika Niederlova, Elizabeth Forsythe, Avishek Prasai, Ales Drobek, Petr Kasparek, Kathryn Sparks, Zdenek Trachtulec, Jan Prochazka, Radislav Sedlacek, Philip Beales, Martina Huranova, Ondrej Stepanek
EMBO Rep. 2021 Feb 3; 22(2): e50785. Published online 2021 Jan 11. doi: 10.15252/embr.202050785
PMCID:
PMC7857422
AbstractArticlePDF–1.6M
7.
GPAT Gene Silencing in Muscle Reduces Diacylglycerols Content and Improves Insulin Action in Diet-Induced Insulin Resistance
Iwona Kojta, Piotr Zabielski, Kamila Roszczyc-Owsiejczuk, Monika Imierska, Emilia Sokołowska, Agnieszka Błachnio-Zabielska
Int J Mol Sci. 2020 Oct; 21(19): 7369. Published online 2020 Oct 6. doi: 10.3390/ijms21197369
PMCID:
PMC7583033
AbstractArticlePDF–3.8M
8.
The sperm associated antigen 6 interactome and its role in spermatogenesis
Yunhao Liu, Ling Zhang, Wei Li, Yuhong Li, Junpin Liu, Shiyang Zhang, Guanglun Pin, Shizhen Song, Pierre F Ray, Christophe Arnoult, Chunghee Cho, Balbina Garcia-Reyes, Uwe Knippschild, Jerome F. Strauss, III, Zhibing Zhang
Reproduction. Author manuscript; available in PMC 2020 Jul 18.
Published in final edited form as: Reproduction. 2019 Aug; 158(2): 181–197. doi: 10.1530/REP-18-0522
PMCID:
PMC7368494
AbstractArticlePDF–1.8M
9.
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931
PMCID:
PMC7227028
AbstractArticlePDF–5.4M
10.
Thioesterase superfamily member 2 promotes hepatic insulin resistance in the setting of glycerol-3-phosphate acyltransferase 1–induced steatosis
Veronika Tillander, Akihiro Miniami, Michele Alves-Bezerra, Rosalind A. Coleman, David E. Cohen
J Biol Chem. 2019 Feb 8; 294(6): 2009–2020. Published online 2018 Dec 6. doi: 10.1074/jbc.RA118.005184
PMCID:
PMC6369296
AbstractArticlePDF–2.9M
11.
Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury
Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa
PLoS Genet. 2016 Sep; 12(9): e1006355. Published online 2016 Sep 30. doi: 10.1371/journal.pgen.1006355
PMCID:
PMC5045200
AbstractArticlePDF–2.9M
12.
Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome
Johanne Dubail, Deepika Vasudevan, Lauren W. Wang, Sarah E. Earp, Michael W. Jenkins, Robert S. Haltiwanger, Suneel S. Apte
Sci Rep. 2016; 6: 33974. Published online 2016 Sep 30. doi: 10.1038/srep33974
PMCID:
PMC5043182
AbstractArticlePDF–3.8M
13.
Glycerol-3-phosphate acyltransferase-1 upregulation by O-GlcNAcylation of Sp1 protects against hypoxia-induced mouse embryonic stem cell apoptosis via mTOR activation
H J Lee, J M Ryu, Y H Jung, K H Lee, D I Kim, H J Han
Cell Death Dis. 2016 Mar; 7(3): e2158. Published online 2016 Mar 24. doi: 10.1038/cddis.2015.410
PMCID:
PMC4823928
AbstractArticlePDF–4.4M
14.
SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression
Laurent Vergnes, Robert G. Chin, Thomas de Aguiar Vallim, Loren G. Fong, Timothy F. Osborne, Stephen G. Young, Karen Reue
J Lipid Res. 2016 Mar; 57(3): 410–421. doi: 10.1194/jlr.M064022
PMCID:
PMC4766990
AbstractArticlePDF–1.7M
15.
Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity
Tatiana L. Fonseca, Gustavo W. Fernandes, Elizabeth A. McAninch, Barbara M. L. C. Bocco, Sherine M. Abdalla, Miriam O. Ribeiro, Petra Mohácsik, Csaba Fekete, Daofeng Li, Xiaoyun Xing, Ting Wang, Balázs Gereben, Antonio C. Bianco
Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45): 14018–14023. Published online 2015 Oct 27. doi: 10.1073/pnas.1508943112
PMCID:
PMC4653175
AbstractArticlePDF–1.0M
16.
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential for murine CD4+ T cell metabolic activation
Robert Faris, Yang-Yi Fan, Alejandra DeAngulo, Robert S. Chapkin, Linda A. deGraffenried, Christopher A. Jolly
Biochim Biophys Acta. Author manuscript; available in PMC 2015 Oct 1.
Published in final edited form as: Biochim Biophys Acta. 2014 Oct; 1842(10): 1475–1482. Published online 2014 Jul 24. doi: 10.1016/j.bbalip.2014.07.009
PMCID:
PMC4169305
AbstractArticlePDF–1.5M
17.
Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor
Chongben Zhang, Daniel E. Cooper, Trisha J. Grevengoed, Lei O. Li, Eric L. Klett, James M. Eaton, Thurl E. Harris, Rosalind A. Coleman
Am J Physiol Endocrinol Metab. 2014 Aug 1; 307(3): E305–E315. Published online 2014 Jun 17. doi: 10.1152/ajpendo.00034.2014
PMCID:
PMC4121579
AbstractArticle
18.
The Central Role of EED in the Orchestration of Polycomb Group Complexes
Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan
Nat Commun. Author manuscript; available in PMC 2014 Jul 24.
Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127
PMCID:
PMC4073494
AbstractArticlePDF–2.1M
19.
Glycerol-3-phosphate Acyltransferase (GPAT)-1, but Not GPAT4, Incorporates Newly Synthesized Fatty Acids into Triacylglycerol and Diminishes Fatty Acid Oxidation
Angela A. Wendel, Daniel E. Cooper, Olga R. Ilkayeva, Deborah M. Muoio, Rosalind A. Coleman
J Biol Chem. 2013 Sep 20; 288(38): 27299–27306. Published online 2013 Aug 1. doi: 10.1074/jbc.M113.485219
PMCID:
PMC3779725
AbstractArticlePDF–782K
20.
Hypoxia-inducible Factor-2α-dependent Hypoxic Induction of Wnt10b Expression in Adipogenic Cells
Young-Kwon Park, Bongju Park, Seongyeol Lee, Kang Choi, Yunwon Moon, Hyunsung Park
J Biol Chem. 2013 Sep 6; 288(36): 26311–26322. Published online 2013 Jul 30. doi: 10.1074/jbc.M113.500835
PMCID:
PMC3764836
AbstractArticlePDF–3.4M

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