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Items: 1 to 20 of 43

1.
The ric-8b protein (resistance to inhibitors of cholinesterase 8b) is key to preserving contractile function in the adult heart
Elena Tsisanova, Muriel Nobles, Sonia Sebastian, Keat-Eng Ng, Alison Thomas, Lee Scott Weinstein, Patricia B. Munroe, Andrew Tinker
J Biol Chem. 2024 Jul; 300(7): 107470. Published online 2024 Jun 13. doi: 10.1016/j.jbc.2024.107470
PMCID:
PMC11277413
AbstractArticlePDF–5.6M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities
Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji
Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888
PMCID:
PMC10191441
AbstractArticlePDF–2.4M
4.
Structures of Ric-8B in complex with Gα protein folding clients reveal isoform specificity mechanisms
Makaía M. Papasergi-Scott, Frank E. Kwarcinski, Maiya Yu, Ouliana Panova, Ann M. Ovrutsky, Georgios Skiniotis, Gregory G. Tall
Structure. Author manuscript; available in PMC 2024 May 4.
Published in final edited form as: Structure. 2023 May 4; 31(5): 553–564.e7. Published online 2023 Mar 16. doi: 10.1016/j.str.2023.02.011
PMCID:
PMC10164081
AbstractArticlePDF–2.7M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
Depletion of Ric-8B leads to reduced mTORC2 activity
Maíra H. Nagai, Victor P. S. Xavier, Luciana M. Gutiyama, Cleiton F. Machado, Alice H. Reis, Elisa R. Donnard, Pedro A. F. Galante, Jose G. Abreu, William T. Festuccia, Bettina Malnic
PLoS Genet. 2020 May; 16(5): e1008255. Published online 2020 May 11. doi: 10.1371/journal.pgen.1008255
PMCID:
PMC7252638
AbstractArticlePDF–3.0M
7.
Ric-8B, an Olfactory Putative GTP Exchange Factor, Amplifies Signal Transduction through the Olfactory-Specific G-Protein Gαolf
Luiz Eduardo C. Von Dannecker, Adriana F. Mercadante, Bettina Malnic
J Neurosci. 2005 Apr 13; 25(15): 3793–3800. doi: 10.1523/JNEUROSCI.4595-04.2005
PMCID:
PMC6724935
AbstractArticlePDF–444K
8.
Conditional Deletion of Ric-8b in Olfactory Sensory Neurons Leads to Olfactory Impairment
Cleiton F. Machado, Maíra H. Nagai, Cassandra S. Lyra, Thiago M. Reis-Silva, André Machado Xavier, Isaias Glezer, Luciano F. Felicio, Bettina Malnic
J Neurosci. 2017 Dec 13; 37(50): 12202–12213. doi: 10.1523/JNEUROSCI.0943-17.2017
Correction in:
J Neurosci. 2018 Jan 24; 38(4): 1054.
PMCID:
PMC6596823
AbstractArticlePDF–2.8M
9.
Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities
Issei S. Shimada, Bandarigoda N. Somatilaka, Sun-Hee Hwang, Ashley G. Anderson, John M. Shelton, Veena Rajaram, Genevieve Konopka, Saikat Mukhopadhyay
Dev Biol. Author manuscript; available in PMC 2020 Jun 1.
Published in final edited form as: Dev Biol. 2019 Jun 1; 450(1): 47–62. Published online 2019 Mar 23. doi: 10.1016/j.ydbio.2019.03.011
PMCID:
PMC6497453
AbstractArticlePDF–5.3M
10.
Conditional ablation of the RFX4 isoform 1 transcription factor: Allele dosage effects on brain phenotype
Ping Xu, James P. Morrison, Julie F. Foley, Deborah J. Stumpo, Toni Ward, Darryl C. Zeldin, Perry J. Blackshear
PLoS One. 2018; 13(1): e0190561. Published online 2018 Jan 3. doi: 10.1371/journal.pone.0190561
PMCID:
PMC5752003
AbstractArticlePDF–16M
11.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
12.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
13.
Evolutionarily Dynamic Alternative Splicing of GPR56 Regulates Regional Cerebral Cortical Patterning
Byoung-Il Bae, Ian Tietjen, Kutay D. Atabay, Gilad D. Evrony, Matthew B. Johnson, Ebenezer Asare, Peter P. Wang, Ayako Y. Murayama, Kiho Im, Steven N. Lisgo, Lynne Overman, Nenad Šestan, Bernard S. Chang, A. James Barkovich, P. Ellen Grant, Meral Topçu, Jeffrey Politsky, Hideyuki Okano, Xianhua Piao, Christopher A. Walsh
Science. Author manuscript; available in PMC 2015 Jun 25.
Published in final edited form as: Science. 2014 Feb 14; 343(6172): 764–768. doi: 10.1126/science.1244392
PMCID:
PMC4480613
AbstractArticlePDF–1.6M
14.
Expression Pattern and Localization Dynamics of Guanine Nucleotide Exchange Factor RIC8 during Mouse Oogenesis
Merly Saare, Sirje Lulla, Tambet Tõnissoo, Riho Meier, Keiu Kask, Katrin Ruisu, Alar Karis, Andres Salumets, Margus Pooga
PLoS One. 2015; 10(6): e0129131. Published online 2015 Jun 10. doi: 10.1371/journal.pone.0129131
PMCID:
PMC4465189
AbstractArticlePDF–23M
15.
A Functional N-terminal Domain in C/EBPβ-LAP* is Required for Interacting with SWI/SNF and to Repress Ric-8B Gene Transcription in Osteoblasts
Rodrigo Aguilar, Rodrigo Grandy, Daniel Meza, Hugo Sepulveda, Philippe Pihan, Andre J. van Wijnen, Jane B. Lian, Gary S. Stein, Janet L. Stein, Martin Montecino
J Cell Physiol. Author manuscript; available in PMC 2015 Oct 1.
Published in final edited form as: J Cell Physiol. 2014 Oct; 229(10): 1521–1528. doi: 10.1002/jcp.24595
PMCID:
PMC4135720
AbstractArticlePDF–837K
16.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
17.
Ric-8 Proteins Are Molecular Chaperones That Direct Nascent G Protein α Subunit Membrane Association
Meital Gabay, Mary E. Pinter, Forrest A. Wright, PuiYee Chan, Andrew J. Murphy, David M. Valenzuela, George D. Yancopoulos, Gregory G. Tall
Sci Signal. Author manuscript; available in PMC 2013 Dec 23.
Published in final edited form as: Sci Signal. 2011 Nov 22; 4(200): 10.1126/scisignal.2002223. Published online 2011 Nov 22. doi: 10.1126/scisignal.2002223
PMCID:
PMC3870195
AbstractArticlePDF–2.9M
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
Detection of Genes Regulated by Lmx1b During Limb Dorsalization
Jennifer M. Feenstra, Kohei Kanaya, Charmaine U Pira, Sarah E. Hoffman, Richard J. Eppey, Kerby C. Oberg
Dev Growth Differ. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Dev Growth Differ. 2012 May; 54(4): 451–462. Published online 2012 Mar 15. doi: 10.1111/j.1440-169X.2012.01331.x
PMCID:
PMC3546822
AbstractArticlePDF–3.2M
20.
Transcriptional Analysis of Gli3 Mutants Identifies Wnt Target Genes in the Developing Hippocampus
Kerstin Hasenpusch-Theil, Dario Magnani, Eleni-Maria Amaniti, Lin Han, Douglas Armstrong, Thomas Theil
Cereb Cortex. 2012 Dec; 22(12): 2878–2893. Published online 2012 Jan 10. doi: 10.1093/cercor/bhr365
PMCID:
PMC3491769
AbstractArticlePDF–5.1M

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