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Items: 1 to 20 of 41

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
ROS scavengers decrease γH2ax spots in motor neuronal nuclei of ALS model mice in vitro
Maya Junghans, Felix John, Hilal Cihankaya, Daniel Schliebs, Konstanze F. Winklhofer, Verian Bader, Johann Matschke, Carsten Theiss, Veronika Matschke
Front Cell Neurosci. 2022; 16: 963169. Published online 2022 Aug 31. doi: 10.3389/fncel.2022.963169
PMCID:
PMC9470831
AbstractArticlePDF–4.6M
3.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
6.
Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant wobbler mice, a model of motor neuron degeneration
Constance S. Petit, Jane J. Lee, Sebastian Boland, Sharan Swarup, Romain Christiano, Zon Weng Lai, Niklas Mejhert, Shane D. Elliott, David McFall, Sara Haque, Eric J. Huang, Roderick T. Bronson, J. Wade Harper, Robert V. Farese, Jr, Tobias C. Walther
Proc Natl Acad Sci U S A. 2020 May 12; 117(19): 10565–10574. Published online 2020 Apr 28. doi: 10.1073/pnas.1913956117
PMCID:
PMC7229683
AbstractArticlePDF–1.7M
7.
Tumor Necrosis Factor α Induces a Metalloprotease-Disintegrin, ADAM8 (CD 156): Implications for Neuron–Glia Interactions during Neurodegeneration
Uwe Schlomann, Silvia Rathke-Hartlieb, Shunsuke Yamamoto, Harald Jockusch, Jörg W. Bartsch
J Neurosci. 2000 Nov 1; 20(21): 7964–7971. doi: 10.1523/JNEUROSCI.20-21-07964.2000
PMCID:
PMC6772711
AbstractArticlePDF–7.3M
8.
Tumor Necrosis Factor-α (TNF-α) Regulates Shedding of TNF-α Receptor 1 by the Metalloprotease-Disintegrin ADAM8: Evidence for a Protease-Regulated Feedback Loop in Neuroprotection
Jörg W. Bartsch, Dirk Wildeboer, Garrit Koller, Silvia Naus, Andrea Rittger, Marcia L. Moss, Yuji Minai, Harald Jockusch
J Neurosci. 2010 Sep 8; 30(36): 12210–12218. doi: 10.1523/JNEUROSCI.1520-10.2010
PMCID:
PMC6633558
AbstractArticlePDF–2.0M
9.
Bcl-2 Sensitivity Differentiates Two Pathways for Motoneuronal Death in the wobbler Mutant Mouse
Muriel Coulpier, Marie-Pierre Junier, Marc Peschanski, Patrick A. Dreyfus
J Neurosci. 1996 Oct 1; 16(19): 5897–5904. doi: 10.1523/JNEUROSCI.16-19-05897.1996
PMCID:
PMC6579179
AbstractArticlePDF–1.5M
10.
Transforming growth factor alpha (TGF alpha) expression in degenerating motoneurons of the murine mutant wobbler: a neuronal signal for astrogliosis?
MP Junier, M Coulpier, N Le Forestier, J Cadusseau, F Suzuki, M Peschanski, PA Dreyfus
J Neurosci. 1994 Jul 1; 14(7): 4206–4216. doi: 10.1523/JNEUROSCI.14-07-04206.1994
PMCID:
PMC6577032
AbstractPDF–2.4M
11.
Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST
Yoko Nakano, Susan Wiechert, Botond Bánfi
Cell Rep. Author manuscript; available in PMC 2019 Jun 9.
Published in final edited form as: Cell Rep. 2019 Apr 16; 27(3): 860–871.e8. doi: 10.1016/j.celrep.2019.03.072
PMCID:
PMC6556397
AbstractArticlePDF–2.3M
12.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
13.
Ubiquitin‐specific protease USP34 controls osteogenic differentiation and bone formation by regulating BMP2 signaling
Yu‐chen Guo, Meng‐yuan Wang, Shi‐wen Zhang, Yun‐shu Wu, Chen‐chen Zhou, Ri‐xin Zheng, Bin Shao, Yuan Wang, Liang Xie, Wei‐qing Liu, Ning‐yuan Sun, Jun‐jun Jing, Ling Ye, Qian‐ming Chen, Quan Yuan
EMBO J. 2018 Oct 15; 37(20): e99398. Published online 2018 Sep 4. doi: 10.15252/embj.201899398
Correction in:
EMBO J. 2020 Oct 15; 39(20): e105578.
PMCID:
PMC6187217
AbstractArticlePDF–2.6M
14.
Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling
Akhee S. Jahan, Maxime Lestra, Lee Kim Swee, Ying Fan, Mart M. Lamers, Fikadu G. Tafesse, Christopher S. Theile, Eric Spooner, Roberto Bruzzone, Hidde L. Ploegh, Sumana Sanyal
Proc Natl Acad Sci U S A. 2016 Feb 9; 113(6): E705–E714. Published online 2016 Jan 25. doi: 10.1073/pnas.1521763113
PMCID:
PMC4760780
AbstractArticlePDF–1.4M
15.
High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes
Robert Brommage, Jeff Liu, Gwenn M Hansen, Laura L Kirkpatrick, David G Potter, Arthur T Sands, Brian Zambrowicz, David R Powell, Peter Vogel
Bone Res. 2014; 2: 14034. Published online 2014 Oct 28. doi: 10.1038/boneres.2014.34
PMCID:
PMC4472125
AbstractArticlePDF–1.6M
16.
EARP, a multisubunit tethering complex involved in endocytic recycling
Christina Schindler, Yu Chen, Jing Pu, Xiaoli Guo, Juan S. Bonifacino
Nat Cell Biol. Author manuscript; available in PMC 2015 Nov 1.
Published in final edited form as: Nat Cell Biol. 2015 May; 17(5): 639–650. Published online 2015 Mar 23. doi: 10.1038/ncb3129
PMCID:
PMC4417048
AbstractArticlePDF–2.9M
17.
The Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Displays Hippocampal Hyperexcitability, and Reduced Number of Interneurons, but No Presynaptic Vesicle Release Impairments
Karina D. Thielsen, Jakob M. Moser, Thomas Schmitt-John, Morten S. Jensen, Kimmo Jensen, Mai Marie Holm
PLoS One. 2013; 8(12): e82767. Published online 2013 Dec 11. doi: 10.1371/journal.pone.0082767
Correction in:
PLoS One. 2015; 10(3): e0121772.
PMCID:
PMC3859636
AbstractArticlePDF–1.6M
18.
Loss of Vps54 Function Leads to Vesicle Traffic Impairment, Protein Mis-Sorting and Embryonic Lethality
Páll Karlsson, Aida Droce, Jakob M. Moser, Simon Cuhlmann, Carolina Ortiz Padilla, Peter Heimann, Jörg W. Bartsch, Annette Füchtbauer, Ernst-Martin Füchtbauer, Thomas Schmitt-John
Int J Mol Sci. 2013 Jun; 14(6): 10908–10925. Published online 2013 May 24. doi: 10.3390/ijms140610908
PMCID:
PMC3709709
AbstractArticlePDF–1.6M
19.
The wobbler mouse, an ALS animal model
Jakob Maximilian Moser, Paolo Bigini, Thomas Schmitt-John
Mol Genet Genomics. 2013; 288(5): 207–229. Published online 2013 Mar 29. doi: 10.1007/s00438-013-0741-0
PMCID:
PMC3664746
AbstractArticlePDF–656K
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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