PMC Links for GEO Profiles (Select 4465157) - PMC

Links from GEO Profiles

Items: 1 to 20 of 142

<< First< Prev

Page of 8

Select item 116193221.

m⁶A RNA methylation orchestrates transcriptional dormancy during paused pluripotency

Evelyne Collignon, Brandon Cho, Giacomo Furlan, Julie Fothergill-Robinson, Sylvia-Bryn Martin, Sarah A. McClymont, Robert L. Ross, Patrick A. Limbach, Miguel Ramalho-Santos

Nat Cell Biol. Author manuscript; available in PMC 2024 Dec 5.

Published in final edited form as: Nat Cell Biol. 2023 Sep; 25(9): 1279–1289. Published online 2023 Sep 7. doi: 10.1038/s41556-023-01212-x

PMCID:: PMC11619322

Abstract Article PDF–6.6M

Select item 115807222.

METTL3‐mediated m6A modification enhances lncRNA H19 stability to promote endothelial cell inflammation and pyroptosis to aggravate atherosclerosis

Feng Tang, Long‐hai Tian, Xiao‐han Zhu, Sen Yang, Huan Zeng, Yong‐yao Yang

FASEB J. 2024 Oct 31; 38(20): e70090. Published online 2024 Oct 21. doi: 10.1096/fj.202401337RR

PMCID:: PMC11580722

Abstract Article PDF–20M

Select item 114530473.

Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance

Yiting Mao, Yicong Meng, Kexin Zou, Ningxin Qin, Yinyu Wang, Jing Yan, PinJia Chen, Yi Cheng, Weihui Shi, Chengliang Zhou, Huixi Chen, Jianzhong Sheng, Xinmei Liu, Jiexue Pan, Hefeng Huang

J Neuroinflammation. 2024; 21: 249. Published online 2024 Oct 4. doi: 10.1186/s12974-024-03248-8

PMCID:: PMC11453047

Abstract Article PDF–8.9M

Select item 113756894.

Up-regulation of RNA m⁶A methyltransferase like-3 expression contributes to arsenic and benzo[a]pyrene co-exposure-induced cancer stem cell-like property and tumorigenesis

Zhishan Wang, Mohammad Burhan Uddin, Po-Shun Wang, Zulong Liu, David Barzideh, Chengfeng Yang

Toxicol Appl Pharmacol. Author manuscript; available in PMC 2024 Sep 5.

Published in final edited form as: Toxicol Appl Pharmacol. 2023 Dec 15; 481: 116764. Published online 2023 Nov 14. doi: 10.1016/j.taap.2023.116764

PMCID:: PMC11375689

Abstract Article PDF–1.8M

Select item 112635505.

METTL3-mediated pre-miR-665/DLX3 m⁶A methylation facilitates the committed differentiation of stem cells from apical papilla

Tingjie Gu, Rong Guo, Yuxin Fang, Ya Xiao, Luyao Chen, Na Li, Xingyun Kelesy Ge, Yijia Shi, Jintao Wu, Ming Yan, Jinhua Yu, Zehan Li

Exp Mol Med. 2024 Jun; 56(6): 1426–1438. Published online 2024 Jun 3. doi: 10.1038/s12276-024-01245-8

PMCID:: PMC11263550

Abstract Article PDF–6.0M

Select item 112361546.

Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads

Haoting Wang, Rie Iida-Norita, Daisuke Mashiko, Anh Hoang Pham, Haruhiko Miyata, Masahito Ikawa

PLoS Genet. 2024 Jun; 20(6): e1011337. Published online 2024 Jun 27. doi: 10.1371/journal.pgen.1011337

PMCID:: PMC11236154

Abstract Article PDF–4.2M

Select item 112347097.

METTL3-mediated NDUFB5 m6A modification promotes cell migration and mitochondrial respiration to promote the wound healing of diabetic foot ulcer

Tao Wang, Xu Li, Yue Tao, Xiaojun Wang, Limeng Li, Jianjun Liu

J Transl Med. 2024; 22: 643. Published online 2024 Jul 9. doi: 10.1186/s12967-024-05463-6

PMCID:: PMC11234709

Abstract Article PDF–11M

Select item 112342068.

METTL3 regulates thyroid cancer differentiation and chemosensitivity by modulating PAX8

Ning Kang, Zewei Zhao, Zhongyu Wang, Junya Ning, Huijuan Wang, Wei Zhang, Xianhui Ruan, Ming Gao, Xiangqian Zheng

Int J Biol Sci. 2024; 20(9): 3426–3441. Published online 2024 Jun 17. doi: 10.7150/ijbs.84797

PMCID:: PMC11234206

Abstract Article PDF–10M

Select item 112164099.

Depletion of Mettl3 in cholinergic neurons causes adult-onset neuromuscular degeneration

Georgia Dermentzaki, Mattia Furlan, Iris Tanaka, Tommaso Leonardi, Paola Rinchetti, Patricia M.S. Passos, Alliny Bastos, Yuna M. Ayala, Jacob H. Hanna, Serge Przedborski, Dario Bonanomi, Mattia Pelizzola, Francesco Lotti

Cell Rep. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Cell Rep. 2024 Apr 23; 43(4): 113999. Published online 2024 Mar 30. doi: 10.1016/j.celrep.2024.113999

PMCID:: PMC11216409

Abstract Article PDF–2.4M

Select item 1110338510.

METTL3 Deficiency Aggravates Hepatic Ischemia/Reperfusion Injury in Mice by Activating the MAPK Signaling Pathway

Yang Gao, Min Wang, Renyi Qin, Chunle Zhao, Jun Gong

Int J Med Sci. 2024; 21(6): 1037–1048. Published online 2024 Apr 15. doi: 10.7150/ijms.94177

PMCID:: PMC11103385

Abstract Article PDF–5.6M

Select item 1108970111.

N6-methyladenosine modification of KLF2 may contribute to endothelial-to-mesenchymal transition in pulmonary hypertension

Kang Kang, Jingjing Xiang, Xingshi Zhang, Yuting Xie, Mengting Zhou, Le Zeng, Junhao Zhuang, Jiahao Kuang, Yuanyuan Lin, Bozhe Hu, Qianmin Xiong, Qing Yin, Qiang Su, Xiaoyun Liao, Jun Wang, Yanqin Niu, Cuilian Liu, Jinglin Tian, Deming Gou

Cell Mol Biol Lett. 2024; 29: 69. Published online 2024 May 13. doi: 10.1186/s11658-024-00590-w

PMCID:: PMC11089701

Abstract Article PDF–1.5M

Select item 1108711312.

Hepatocyte-specific METTL3 ablation by Alb-iCre mice (GPT), but not by Alb-Cre mice (JAX), resulted in acute liver failure (ALF) and postnatal lethality

Shihao Huang, Yingchun Li, Bingjie Wang, Zhihao Zhou, Yonglong Li, Lingjun Shen, Jinge Cong, Liuxin Han, Xudong Xiang, Jiawei Xia, Danhua He, Zhanlin Zhao, Ying Zhou, Qiwen Li, Guanqi Dai, Hanzhang Shen, Taoyan Lin, Aibing Wu, Junshuang Jia, Dong Xiao, Jing Li, Wentao Zhao, Xiaolin Lin

Aging (Albany NY) 2024 Apr 30; 16(8): 7217–7248. Published online 2024 Apr 22. doi: 10.18632/aging.205753

PMCID:: PMC11087113

Abstract Article PDF–3.9M

Select item 1104268113.

Redox regulation of m⁶A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes

Dario F. De Jesus, Zijie Zhang, Natalie K. Brown, Xiaolu Li, Ling Xiao, Jiang Hu, Matthew J. Gaffrey, Garrett Fogarty, Sevim Kahraman, Jiangbo Wei, Giorgio Basile, Tariq M. Rana, Clayton Mathews, Alvin C. Powers, Audrey V. Parent, Mark A. Atkinson, Sirano Dhe-Paganon, Decio L. Eizirik, Wei-Jun Qian, Chuan He, Rohit N. Kulkarni

Nat Cell Biol. Author manuscript; available in PMC 2024 Apr 24.

Published in final edited form as: Nat Cell Biol. 2024 Mar; 26(3): 421–437. Published online 2024 Feb 26. doi: 10.1038/s41556-024-01368-0

PMCID:: PMC11042681

Abstract Article PDF–8.2M

Select item 1091766014.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 1091641915.

NRF1 mitigates motor dysfunction and dopamine neuron degeneration in mice with Parkinson's disease by promoting GLRX m⁶A methylation through upregulation of METTL3 transcription

Xin Gong, Mengyi Huang, Lei Chen

CNS Neurosci Ther. 2024 Mar; 30(3): e14441. Published online 2023 Sep 22. doi: 10.1111/cns.14441

PMCID:: PMC10916419

Abstract Article PDF–17M

Select item 1090601516.

METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy

Fangfang Wang, Juan Bai, Xin Zhang, Dali Wang, Xin Zhang, Jingwen Xue, Haoyang Chen, Shuxiang Wang, Baojin Chi, Jing Li, Xiaoru Ma

J Diabetes Investig. 2024 Mar; 15(3): 288–299. Published online 2023 Nov 28. doi: 10.1111/jdi.14113

PMCID:: PMC10906015

Abstract Article PDF–3.8M

Select item 1085443817.

Mettl3-catalyzed m⁶A regulates histone modifier and modification expression in self-renewing somatic tissue

Alexandra M. Maldonado López, Eun Kyung Ko, Sijia Huang, Gina Pacella, Nina Kuprasertkul, Carina A. D’souza, Raúl A. Reyes Hueros, Hui Shen, Julian Stoute, Heidi Elashal, Morgan Sinkfield, Amy Anderson, Stephen Prouty, Hua-Bing Li, John T. Seykora, Kathy Fange Liu, Brian C. Capell

Sci Adv. 2023 Sep; 9(35): eadg5234. Published online 2023 Sep 1. doi: 10.1126/sciadv.adg5234

PMCID:: PMC10854438

Abstract Article PDF–1.5M

Select item 1083461618.

METTL3 regulates TFRC ubiquitination and ferroptosis through stabilizing NEDD4L mRNA to impact stroke

Wenjie Su, Xiang Yu, Shan Wang, Xu Wang, Zheng Dai, Yi Li

Cell Biol Toxicol. 2024; 40(1): 8. Published online 2024 Feb 2. doi: 10.1007/s10565-024-09844-x

PMCID:: PMC10834616

Abstract Article PDF–7.0M

Select item 1081739619.

METTL3-dependent N6-methyladenosine modification is involved in berberine-mediated neuroprotection in ischemic stroke by enhancing the stability of NEAT1 in astrocytes

Junya Hu, Huijie Duan, Junqing Zou, Wangli Ding, Ziqiao Wei, Qiang Peng, Zhongyuan Li, Rui Duan, Jianguo Sun, Junrong Zhu

Aging (Albany NY) 2024 Jan 15; 16(1): 299–321. Published online 2024 Jan 4. doi: 10.18632/aging.205369

PMCID:: PMC10817396

Abstract Article PDF–2.1M

Select item 1080963720.

METTL3 promotes osteoblast ribosome biogenesis and alleviates periodontitis

Yiwen Zhang, Yiping Kong, Wenjie Zhang, Jinlin He, Zhanqi Zhang, Yongjie Cai, Yiqing Zhao, Qiong Xu

Clin Epigenetics. 2024; 16: 18. Published online 2024 Jan 24. doi: 10.1186/s13148-024-01628-8

PMCID:: PMC10809637

Abstract Article PDF–4.6M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 142

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity