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Items: 1 to 20 of 40

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
COX17 acetylation via MOF–KANSL complex promotes mitochondrial integrity and function
Sukanya Guhathakurta, Niyazi Umut Erdogdu, Juliane J. Hoffmann, Iga Grzadzielewska, Alexander Schendzielorz, Janine Seyfferth, Christoph U. Mårtensson, Mauro Corrado, Adam Karoutas, Bettina Warscheid, Nikolaus Pfanner, Thomas Becker, Asifa Akhtar
Nat Metab. 2023; 5(11): 1931–1952. Published online 2023 Oct 9. doi: 10.1038/s42255-023-00904-w
PMCID:
PMC10663164
AbstractArticlePDF–28M
3.
MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters
Dongmei Wang, Haimin Li, Navdeep S. Chandel, Yali Dou, Rui Yi
Nat Commun. 2023; 14: 4404. Published online 2023 Jul 21. doi: 10.1038/s41467-023-40108-0
PMCID:
PMC10362062
AbstractArticlePDF–9.3M
4.
Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models
Hamid Meziane, Marie-Christine Birling, Olivia Wendling, Sophie Leblanc, Aline Dubos, Mohammed Selloum, Guillaume Pavlovic, Tania Sorg, Vera M. Kalscheuer, Pierre Billuart, Frédéric Laumonnier, Jamel Chelly, Hans van Bokhoven, Yann Herault
Biomedicines. 2022 Dec; 10(12): 3148. Published online 2022 Dec 6. doi: 10.3390/biomedicines10123148
PMCID:
PMC9775489
AbstractArticlePDF–2.8M
5.
Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice
Ting Li, Dingyi Lu, Chengcheng Yao, Tingting Li, Hua Dong, Zhan Li, Guang Xu, Jiayi Chen, Hao Zhang, Xiaoyu Yi, Haizhen Zhu, Guangqin Liu, Kaiqing Wen, Haixin Zhao, Jun Gao, Yakun Zhang, Qiuying Han, Teng Li, Weina Zhang, Jie Zhao, Tao Li, Zhaofang Bai, Moshi Song, Xinhua He, Tao Zhou, Qing Xia, Ailing Li, Xin Pan
Nat Commun. 2022; 13: 931. Published online 2022 Feb 17. doi: 10.1038/s41467-022-28613-0
Correction in:
Nat Commun. 2022; 13: 1575.
PMCID:
PMC8854428
AbstractArticlePDF–4.3M
6.
APC7 Mediates Ubiquitin Signaling in Constitutive Heterochromatin in the Developing Mammalian Brain
Cole J. Ferguson, Olivia Urso, Tatyana Bodrug, Brandon M. Gassaway, Edmond R. Watson, Jesuraj R. Prabu, Pablo Lara-Gonzalez, Raquel C. Martinez-Chacin, Dennis Y. Wu, Karlla W. Brigatti, Erik G. Puffenberger, Cora M. Taylor, Barbara Haas-Givler, Robert N. Jinks, Kevin A. Strauss, Arshad Desai, Harrison W. Gabel, Steven P. Gygi, Brenda A. Schulman, Nicholas G. Brown, Azad Bonni
Mol Cell. Author manuscript; available in PMC 2023 Jan 6.
Published in final edited form as: Mol Cell. 2022 Jan 6; 82(1): 90–105.e13. Published online 2021 Dec 22. doi: 10.1016/j.molcel.2021.11.031
PMCID:
PMC8741739
AbstractArticlePDF–4.4M
7.
Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism
Arielle N. Valdez-Sinon, Austin Lai, Liang Shi, Carly L. Lancaster, Avanti Gokhale, Victor Faundez, Gary J. Bassell
iScience. 2020 May 22; 23(5): 101132. Published online 2020 May 1. doi: 10.1016/j.isci.2020.101132
PMCID:
PMC7236060
AbstractArticlePDF–6.1M
8.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
9.
Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition
Thomas Arbogast, Giovanni Iacono, Claire Chevalier, Nurudeen O. Afinowi, Xander Houbaert, Matthijs C. van Eede, Christine Laliberte, Marie-Christine Birling, Katrin Linda, Hamid Meziane, Mohammed Selloum, Tania Sorg, Nael Nadif Kasri, David A. Koolen, Henk G. Stunnenberg, R. Mark Henkelman, Maksym Kopanitsa, Yann Humeau, Bert B. A. De Vries, Yann Herault
PLoS Genet. 2017 Jul; 13(7): e1006886. Published online 2017 Jul 13. doi: 10.1371/journal.pgen.1006886
PMCID:
PMC5531616
AbstractArticlePDF–7.4M
10.
Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons
Teresa Rodríguez-Martín, Amy M. Pooler, Dawn H.W. Lau, Gábor M. Mórotz, Kurt J. De Vos, Jonathan Gilley, Michael P. Coleman, Diane P. Hanger
Neurobiol Dis. 2016 Jan; 85: 1–10. doi: 10.1016/j.nbd.2015.10.007
PMCID:
PMC4684147
AbstractArticle
11.
Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells
Paulina A. Latos, Angela Goncalves, David Oxley, Hisham Mohammed, Ernest Turro, Myriam Hemberger
Nat Commun. 2015; 6: 7776. Published online 2015 Jul 24. doi: 10.1038/ncomms8776
PMCID:
PMC4525203
AbstractArticlePDF–1.9M
12.
A Cdh1-APC/FMRP Ubiquitin Signaling Link Drives mGluR-Dependent Synaptic Plasticity in the Mammalian Brain
Ju Huang, Yoshiho Ikeuchi, Marcos Malumbres, Azad Bonni
Neuron. Author manuscript; available in PMC 2016 May 6.
Published in final edited form as: Neuron. 2015 May 6; 86(3): 726–739. Published online 2015 Apr 23. doi: 10.1016/j.neuron.2015.03.049
PMCID:
PMC4492466
AbstractArticlePDF–952K
13.
The novel protein MANI modulates neurogenesis and neurite-cone growth
Manisha Mishra, Hiroyasu Akatsu, Klaus Heese
J Cell Mol Med. 2011 Aug; 15(8): 1713–1725. Published online 2011 Jul 13. doi: 10.1111/j.1582-4934.2010.01134.x
PMCID:
PMC4373362
AbstractArticlePDF–1.4M
14.
MOF-associated complexes ensure stem cell identity and Xist repression
Tomasz Chelmicki, Friederike Dündar, Matthew James Turley, Tasneem Khanam, Tugce Aktas, Fidel Ramírez, Anne-Valerie Gendrel, Patrick Rudolf Wright, Pavankumar Videm, Rolf Backofen, Edith Heard, Thomas Manke, Asifa Akhtar
eLife. 2014; 3: e02024. Published online 2014 May 19. doi: 10.7554/eLife.02024
PMCID:
PMC4059889
AbstractArticlePDF–9.7M
15.
Tbx5-Hedgehog Molecular Networks Are Essential in the Second Heart Field for Atrial Septation
Linglin Xie, Andrew D. Hoffmann, Ozanna Burnicka-Turek, Joshua M. Friedland-Little, Ke Zhang, Ivan P. Moskowitz
Dev Cell. Author manuscript; available in PMC 2014 Feb 3.
Published in final edited form as: Dev Cell. 2012 Aug 14; 23(2): 280–291. doi: 10.1016/j.devcel.2012.06.006
PMCID:
PMC3912192
AbstractArticlePDF–2.0M
16.
Cell cycle adaptations of embryonic stem cells
Andrea Ballabeni, In-Hyun Park, Rui Zhao, Weiping Wang, Paul H. Lerou, George Q. Daley, Marc W. Kirschner
Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48): 19252–19257. Published online 2011 Nov 14. doi: 10.1073/pnas.1116794108
PMCID:
PMC3228440
AbstractArticlePDF–935K
17.
SIRT2 Maintains Genome Integrity and Suppresses Tumorigenesis through Regulating APC/C Activity
Hyun-Seok Kim, Athanassios Vassilopoulos, Rui-Hong Wang, Tyler Lahusen, Zhen Xiao, Xiaoling Xu, Cuiling Li, Timothy D. Veenstra, Bing Li, Hongtao Yu, Junfang Ji, Xin Wei Wang, Seong-Hoon Park, Yong I. Cha, David Gius, Chu-Xia Deng
Cancer Cell. Author manuscript; available in PMC 2012 Oct 18.
Published in final edited form as: Cancer Cell. 2011 Oct 18; 20(4): 487–499. doi: 10.1016/j.ccr.2011.09.004
PMCID:
PMC3199577
AbstractArticlePDF–3.6M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition
Jing Chen, Collin Melton, Nayoung Suh, Jeong Su Oh, Kathleen Horner, Fang Xie, Claudio Sette, Robert Blelloch, Marco Conti
Genes Dev. 2011 Apr; 25(7): 755–766. doi: 10.1101/gad.2028911
PMCID:
PMC3070937
AbstractArticlePDF–965K
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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