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Select item 95531231.

Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics

Natalia Akkuratova, Louis Faure, Polina Kameneva, Maria Eleni Kastriti, Igor Adameyko

Front Endocrinol (Lausanne) 2022; 13: 1020000. Published online 2022 Sep 27. doi: 10.3389/fendo.2022.1020000

PMCID:: PMC9553123

Article PDF–28M

Select item 87149762.

Salt sensitivity of volume and blood pressure in a mouse with globally reduced ENaC γ-subunit expression

Evan C. Ray, Ashley Pitzer, Tracey Lam, Alexa Jordahl, Ritam Patel, Mingfang Ao, Allison Marciszyn, Aaliyah Winfrey, Yaacov Barak, Shaohu Sheng, Annet Kirabo, Thomas R. Kleyman

Am J Physiol Renal Physiol. 2021 Dec 1; 321(6): F705–F714. Published online 2021 Oct 11. doi: 10.1152/ajprenal.00559.2020

PMCID:: PMC8714976

Article

Select item 86743923.

METTL9 mediated N1-histidine methylation of zinc transporters is required for tumor growth

Mengyue Lv, Dan Cao, Liwen Zhang, Chi Hu, Shukai Li, Panrui Zhang, Lianbang Zhu, Xiao Yi, Chaoliang Li, Alin Yang, Zhentao Yang, Yi Zhu, Kaiguang Zhang, Wen Pan

Protein Cell. 2021 Dec; 12(12): 965–970. Published online 2021 Jul 4. doi: 10.1007/s13238-021-00857-4

PMCID:: PMC8674392

Article PDF–1.2M

Select item 85715224.

siRNA screening identifies METTL9 as a histidine Nπ-methyltransferase that targets the proinflammatory protein S100A9

Hiroaki Daitoku, Momoka Someya, Koichiro Kako, Takahiro Hayashi, Tatsuya Tajima, Hikari Haruki, Naoki Sekiguchi, Toru Uetake, Yuto Akimoto, Akiyoshi Fukamizu

J Biol Chem. 2021 Nov; 297(5): 101230. Published online 2021 Sep 23. doi: 10.1016/j.jbc.2021.101230

PMCID:: PMC8571522

Article PDF–1.8M

Select item 85649135.

Impairment in renal medulla development underlies salt wasting in Clc-k2 channel deficiency

Meng-Hsuan Lin, Jen-Chi Chen, Xuejiao Tian, Chia-Ming Lee, I-Shing Yu, Yi-Fen Lo, Shinichi Uchida, Chou-Long Huang, Bi-Chang Chen, Chih-Jen Cheng

JCI Insight. 2021 Oct 22; 6(20): e151039. Published online 2021 Oct 22. doi: 10.1172/jci.insight.151039

PMCID:: PMC8564913

Article PDF–6.6M

Select item 85354106.

Deletion of the Gamma Subunit of ENaC in Endothelial Cells Does Not Protect against Renal Ischemia Reperfusion Injury

Stephanie M. Mutchler, Mahpara Hasan, Donald E. Kohan, Thomas R. Kleyman, Roderick J. Tan

Int J Mol Sci. 2021 Oct; 22(20): 10914. Published online 2021 Oct 9. doi: 10.3390/ijms222010914

PMCID:: PMC8535410

Article PDF–2.5M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Article PDF–2.0M

Select item 78731848.

The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

Erna Davydova, Tadahiro Shimazu, Maren Kirstin Schuhmacher, Magnus E. Jakobsson, Hanneke L. D. M. Willemen, Tongri Liu, Anders Moen, Angela Y. Y. Ho, Jędrzej Małecki, Lisa Schroer, Rita Pinto, Takehiro Suzuki, Ida A. Grønsberg, Yoshihiro Sohtome, Mai Akakabe, Sara Weirich, Masaki Kikuchi, Jesper V. Olsen, Naoshi Dohmae, Takashi Umehara, Mikiko Sodeoka, Valentina Siino, Michael A. McDonough, Niels Eijkelkamp, Christopher J. Schofield, Albert Jeltsch, Yoichi Shinkai, Pål Ø. Falnes

Nat Commun. 2021; 12: 891. Published online 2021 Feb 9. doi: 10.1038/s41467-020-20670-7

PMCID:: PMC7873184

Article PDF–1.8M

Select item 76631239.

Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality

Rajiv Kumar Sah, Jun Ma, Fatoumata Binta Bah, Zhenkai Xing, Salah Adlat, Zin Ma Oo, Yajun Wang, Noor Bahadar, Ameer Ali Bohio, Farooq Hayel Nagi, Xuechao Feng, Luqing Zhang, Yaowu Zheng

Int J Mol Sci. 2020 Nov; 21(21): 8223. Published online 2020 Nov 3. doi: 10.3390/ijms21218223

PMCID:: PMC7663123

Article PDF–4.7M

Select item 721741710.

Interaction between Epithelial Sodium Channel γ-Subunit and Claudin-8 Modulates Paracellular Sodium Permeability in Renal Collecting Duct

Ali Sassi, Yubao Wang, Alexandra Chassot, Olga Komarynets, Isabelle Roth, Valérie Olivier, Gilles Crambert, Eva Dizin, Emilie Boscardin, Edith Hummler, Eric Feraille

J Am Soc Nephrol. 2020 May; 31(5): 1009–1023. Published online 2020 Apr 3. doi: 10.1681/ASN.2019080790

PMCID:: PMC7217417

Article

Select item 715276411.

Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel

Shujie Shi, Nicolas Montalbetti, Xueqi Wang, Brittney M. Rush, Allison L. Marciszyn, Catherine J. Baty, Roderick J. Tan, Marcelo D. Carattino, Thomas R. Kleyman

J Biol Chem. 2020 Apr 10; 295(15): 4950–4962. Published online 2020 Feb 20. doi: 10.1074/jbc.RA119.011789

PMCID:: PMC7152764

Article PDF–2.8M

Select item 639005712.

Insulin ameliorates pulmonary edema through the upregulation of epithelial sodium channel via the PI3K/SGK1 pathway in mice with lipopolysaccharide-induced lung injury

Wang Deng, Chang-Yi Li, Jin Tong, Jing He, Yan Zhao, Dao-Xin Wang

Mol Med Rep. 2019 Mar; 19(3): 1665–1677. Published online 2019 Jan 2. doi: 10.3892/mmr.2019.9809

PMCID:: PMC6390057

Article PDF–2.6M

Select item 629804013.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Article PDF–1.2M

Select item 623163814.

Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each

Afzal M. Dogar, Ramona Pauchard-Batschulat, Barbara Grisoni-Neupert, Larry Richman, Alexandra Paillusson, Sylvain Pradervand, Otto Hagenbüchle, Giovanna Ambrosini, Christoph D. Schmid, Philipp Bucher, Lukas C. Kühn

PLoS One. 2018; 13(11): e0206823. Published online 2018 Nov 12. doi: 10.1371/journal.pone.0206823

PMCID:: PMC6231638

Article PDF–3.8M

Select item 613370415.

Glucocorticoid receptor isoform–specific regulation of development, circadian rhythm, and inflammation in mice

Robert H. Oakley, Sivapriya Ramamoorthy, Julie F. Foley, Jonathan T. Busada, Nick Z. Lu, John A. Cidlowski

FASEB J. 2018 Oct; 32(10): 5258–5271. Published online 2018 Apr 19. doi: 10.1096/fj.201701153R

PMCID:: PMC6133704

Article

Select item 589922716.

Physiological regulation of the epithelial Na⁺ channel by casein kinase II

Jonathan M. Berman, Elena Mironova, James D. Stockand

Am J Physiol Renal Physiol. 2018 Mar 1; 314(3): F367–F372. Published online 2017 Oct 11. doi: 10.1152/ajprenal.00469.2017

PMCID:: PMC5899227

Article

Select item 589922117.

N-linked glycans are required on epithelial Na⁺ channel subunits for maturation and surface expression

Ossama B. Kashlan, Carol L. Kinlough, Michael M. Myerburg, Shujie Shi, Jingxin Chen, Brandon M. Blobner, Teresa M. Buck, Jeffrey L. Brodsky, Rebecca P. Hughey, Thomas R. Kleyman

Am J Physiol Renal Physiol. 2018 Mar 1; 314(3): F483–F492. Published online 2017 Nov 29. doi: 10.1152/ajprenal.00195.2017

PMCID:: PMC5899221

Article

Select item 582758818.

Plasma Potassium Determines NCC Abundance in Adult Kidney-Specific γENaC Knockout

Emilie Boscardin, Romain Perrier, Chloé Sergi, Marc P. Maillard, Johannes Loffing, Dominique Loffing-Cueni, Robert Koesters, Bernard C. Rossier, Edith Hummler

J Am Soc Nephrol. 2018 Mar; 29(3): 977–990. Published online 2018 Jan 25. doi: 10.1681/ASN.2017030345

PMCID:: PMC5827588

Article

Select item 575227219.

The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion

Marzia Scortegagna, Annabel Berthon, Nikolaos Settas, Andreas Giannakou, Guillermina Garcia, Jian-Liang Li, Brian James, Robert C. Liddington, José G. Vilches-Moure, Constantine A. Stratakis, Ze’ev A. Ronai

JCI Insight. 2017 Dec 7; 2(23): e97128. Published online 2017 Dec 7. doi: 10.1172/jci.insight.97128

PMCID:: PMC5752272

Article PDF–9.0M

Select item 540706720.

ENaC and ROMK activity are inhibited in the DCT2/CNT of TgWnk4^PHAII mice

Chengbiao Zhang, Lijun Wang, Xiao-Tong Su, Junhui Zhang, Dao-Hong Lin, Wen-Hui Wang

Am J Physiol Renal Physiol. 2017 Apr 1; 312(4): F682–F688. Published online 2016 Nov 9. doi: 10.1152/ajprenal.00420.2016

PMCID:: PMC5407067

Article

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