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Items: 1 to 20 of 175

1.
Deciphering the role of retinoic acid in hepatic patterning and induction in the mouse
Taylor M. Guertin, Amrita Palaria, Jesse Mager, Lisa L. Sandell, Paul A. Trainor, Kimberly D. Tremblay
Dev Biol. Author manuscript; available in PMC 2024 Dec 17.
Published in final edited form as: Dev Biol. 2022 Nov; 491: 31–42. Published online 2022 Aug 23. doi: 10.1016/j.ydbio.2022.08.003
PMCID:
PMC11651638
AbstractArticlePDF–3.0M
2.
TBX3 is essential for establishment of the posterior boundary of anterior genes and upregulation of posterior genes together with HAND2 during the onset of limb bud development
Geoffrey Soussi, Ausra Girdziusaite, Shalu Jhanwar, Victorio Palacio, Marco Notaro, Rushikesh Sheth, Rolf Zeller, Aimée Zuniga
Development. 2024 Jun 1; 151(11): dev202722. Published online 2024 Jun 3. doi: 10.1242/dev.202722
PMCID:
PMC11190573
AbstractArticle
3.
Mapping catalytically engaged TOP2B in neurons reveals the principles of topoisomerase action within the genome
Amir Segev, Lance Heady, Morgan Crewe, Ram Madabhushi
Cell Rep. Author manuscript; available in PMC 2024 May 2.
Published in final edited form as: Cell Rep. 2024 Feb 27; 43(2): 113809. Published online 2024 Feb 19. doi: 10.1016/j.celrep.2024.113809
PMCID:
PMC11064056
AbstractArticlePDF–3.0M
4.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
5.
Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves
Rachel Queen, Moira Crosier, Lorraine Eley, Janet Kerwin, Jasmin E. Turner, Jianshi Yu, Ahlam Alqahtani, Tamilvendhan Dhanaseelan, Lynne Overman, Hannah Soetjoadi, Richard Baldock, Jonathan Coxhead, Veronika Boczonadi, Alex Laude, Simon J. Cockell, Maureen A. Kane, Steven Lisgo, Deborah J. Henderson
PLoS Genet. 2023 Nov; 19(11): e1010777. Published online 2023 Nov 27. doi: 10.1371/journal.pgen.1010777
PMCID:
PMC10703419
AbstractArticlePDF–9.6M
6.
GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter
Jennifer Kurz, Anna-Carina Weiss, Timo H.-W. Lüdtke, Lena Deuper, Mark-Oliver Trowe, Hauke Thiesler, Herbert Hildebrandt, Joerg Heineke, Stephen A. Duncan, Andreas Kispert
Development. 2022 Aug 1; 149(15): dev200522. Published online 2022 Jul 29. doi: 10.1242/dev.200522
PMCID:
PMC10656427
AbstractArticle
7.
Retinoic Acid Receptor β Loss in Hepatocytes Increases Steatosis and Elevates the Integrated Stress Response in Alcohol-Associated Liver Disease
Marta Melis, Steven E. Trasino, Xiao-Han Tang, Andrew Rappa, Tuo Zhang, Lihui Qin, Lorraine J. Gudas
Int J Mol Sci. 2023 Aug; 24(15): 12035. Published online 2023 Jul 27. doi: 10.3390/ijms241512035
PMCID:
PMC10418449
AbstractArticlePDF–5.8M
8.
Nucleophagy contributes to genome stability through degradation of type II topoisomerases A and B and nucleolar components
Gabriel Muciño-Hernández, Pilar Sarah Acevo-Rodríguez, Sandra Cabrera-Benitez, Adán Oswaldo Guerrero, Horacio Merchant-Larios, Susana Castro-Obregón
J Cell Sci. 2023 Jan 1; 136(1): jcs260563. Published online 2023 Jan 12. doi: 10.1242/jcs.260563
PMCID:
PMC10112964
AbstractArticle
9.
Calcineurin dephosphorylates topoisomerase IIβ and regulates the formation of neuronal-activity-induced DNA breaks
Ilse Delint-Ramirez, Lahiri Konada, Lance Heady, Richard Rueda, Alvaro Sebastian Vaca Jacome, Eric Marlin, Charlotte Marchioni, Amir Segev, Oleg Kritskiy, Satoko Yamakawa, Andrew H. Reiter, Li-Huei Tsai, Ram Madabhushi
Mol Cell. Author manuscript; available in PMC 2023 Oct 20.
Published in final edited form as: Mol Cell. 2022 Oct 20; 82(20): 3794–3809.e8. Published online 2022 Oct 6. doi: 10.1016/j.molcel.2022.09.012
PMCID:
PMC9990814
AbstractArticlePDF–2.6M
10.
Synergistic activation of RARβ and RARγ nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARα-controlled programs
Aysis Koshy, Elodie Mathieux, François Stüder, Aude Bramoulle, Michele Lieb, Bruno Maria Colombo, Hinrich Gronemeyer, Marco Antonio Mendoza-Parra
Life Sci Alliance. 2023 Feb; 6(2): e202201627. Published online 2022 Nov 29. doi: 10.26508/lsa.202201627
PMCID:
PMC9711859
AbstractArticlePDF–4.7M
11.
Mapping Brain Gene Coexpression in Daytime Transcriptomes Unveils Diurnal Molecular Networks and Deciphers Perturbation Gene Signatures
Nan Wang, Peter Langfelder, Matthew Stricos, Lalini Ramanathan, Jeffrey B. Richman, Raymond Vaca, Mary Plascencia, Xiaofeng Gu, Shasha Zhang, T. Katherine Tamai, Liguo Zhang, Fuying Gao, Koliane Ouk, Xiang Lu, Leonya Ivanov, Tom Vogt, Qing Richard Lu, A. Jennifer Morton, Christopher Colwell, Jeffrey S. Aaronson, Jim Rosinski, Steve Horvath, X. William Yang
Neuron. Author manuscript; available in PMC 2023 Oct 19.
Published in final edited form as: Neuron. 2022 Oct 19; 110(20): 3318–3338.e9. doi: 10.1016/j.neuron.2022.09.028
PMCID:
PMC9665885
AbstractArticlePDF–4.5M
12.
Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome
Sasha L. Fulton, Wendy Wenderski, Ashley E. Lepack, Andrew L. Eagle, Tomas Fanutza, Ryan M. Bastle, Aarthi Ramakrishnan, Emma C. Hays, Arianna Neal, Jaroslav Bendl, Lorna A. Farrelly, Amni Al-Kachak, Yang Lyu, Bulent Cetin, Jennifer C. Chan, Tina N. Tran, Rachael L. Neve, Randall J. Roper, Kristen J. Brennand, Panos Roussos, John C. Schimenti, Allyson K. Friedman, Li Shen, Robert D. Blitzer, Alfred J. Robison, Gerald R. Crabtree, Ian Maze
Nat Commun. 2022; 13: 6384. Published online 2022 Oct 26. doi: 10.1038/s41467-022-34200-0
PMCID:
PMC9606253
AbstractArticlePDF–4.0M
13.
Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity
Katharina Schönberger, Nadine Obier, Mari Carmen Romero-Mulero, Pierre Cauchy, Julian Mess, Polina V. Pavlovich, Yu Wei Zhang, Michael Mitterer, Jasmin Rettkowski, Maria-Eleni Lalioti, Karin Jäcklein, Jonathan D. Curtis, Betty Féret, Pia Sommerkamp, Claudia Morganti, Keisuke Ito, Norbert B. Ghyselinck, Eirini Trompouki, Joerg M. Buescher, Erika L. Pearce, Nina Cabezas-Wallscheid
Cell Stem Cell. Author manuscript; available in PMC 2022 May 11.
Published in final edited form as: Cell Stem Cell. 2022 Jan 6; 29(1): 131–148.e10. Published online 2021 Oct 26. doi: 10.1016/j.stem.2021.10.002
PMCID:
PMC9093043
AbstractArticlePDF–3.5M
14.
Regulation of Prefrontal Patterning and Connectivity by Retinoic Acid
Mikihito Shibata, Kartik Pattabiraman, Belen Lorente-Galdos, David Andrijevic, Suel-Kee Kim, Navjot Kaur, Sydney K. Muchnik, Xiaojun Xing, Gabriel Santpere, Andre M. M. Sousa, Nenad Sestan
Nature. Author manuscript; available in PMC 2022 Apr 19.
Published in final edited form as: Nature. 2021 Oct; 598(7881): 483–488. Published online 2021 Oct 1. doi: 10.1038/s41586-021-03953-x
PMCID:
PMC9018119
AbstractArticlePDF–12M
15.
Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum
Zihao Su, Ziwu Wang, Susan Lindtner, Lin Yang, Zicong Shang, Yu Tian, Rongliang Guo, Yan You, Wenhao Zhou, John L. Rubenstein, Zhengang Yang, Zhuangzhi Zhang
Development. 2022 Feb 15; 149(4): dev200035. Published online 2022 Feb 23. doi: 10.1242/dev.200035
PMCID:
PMC8918808
AbstractArticle
16.
Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization
Yan Yin, Meade E. Haller, Sangappa B. Chadchan, Ramakrishna Kommagani, Liang Ma
JCI Insight. 2021 Sep 8; 6(17): e150254. Published online 2021 Sep 8. doi: 10.1172/jci.insight.150254
PMCID:
PMC8492326
AbstractArticlePDF–3.4M
17.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
18.
A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects
Hélène Choquet, Ronald B. Melles, Deepti Anand, Jie Yin, Gabriel Cuellar-Partida, Wei Wang, 23andMe Research Team, Thomas J. Hoffmann, K. Saidas Nair, Pirro G. Hysi, Salil A. Lachke, Eric Jorgenson
Nat Commun. 2021; 12: 3595. Published online 2021 Jun 14. doi: 10.1038/s41467-021-23873-8
PMCID:
PMC8203611
AbstractArticlePDF–1.9M
19.
Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity
Andres Canela, Yaakov Maman, Shar-yin N. Huang, Gordana Wutz, Wen Tang, Guido Zagnoli-Vieira, Elsa Callen, Nancy Wong, Amanda Day, Jan-Michael Peters, Keith W. Caldecott, Yves Pommier, André Nussenzweig
Mol Cell. Author manuscript; available in PMC 2021 Jun 2.
Published in final edited form as: Mol Cell. 2019 Jul 25; 75(2): 252–266.e8. Published online 2019 Jun 12. doi: 10.1016/j.molcel.2019.04.030
PMCID:
PMC8170508
AbstractArticlePDF–2.4M
20.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M

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