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Items: 1 to 20 of 28

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Loss of cardiac mitochondrial complex I persulfidation impairs NAD+ homeostasis in aging
Maria-Kyriaki Drekolia, Christina Karantanou, Ilka Wittig, Yuanyuan Li, Dominik C. Fuhrmann, Bernhard Brüne, Antonia Katsouda, Jiong Hu, Andreas Papapetropoulos, Sofia-Iris Bibli
Redox Biol. 2024 Feb; 69: 103014. Published online 2023 Dec 25. doi: 10.1016/j.redox.2023.103014
PMCID:
PMC10792955
AbstractArticlePDF–5.5M
3.
CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway
Antonia Katsouda, Maria Markou, Paraskevas Zampas, Aimilia Varela, Constantinos H. Davos, Valentina Vellecco, Giuseppe Cirino, Mariarosaria Bucci, Andreas Papapetropoulos
Front Pharmacol. 2023; 14: 1090654. Published online 2023 Feb 13. doi: 10.3389/fphar.2023.1090654
PMCID:
PMC9969096
AbstractArticlePDF–1.6M
4.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
5.
MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity
Antonia Katsouda, Dimitrios Valakos, Vasilios S. Dionellis, Sofia-Iris Bibli, Ioannis Akoumianakis, Sevasti Karaliota, Karim Zuhra, Ingrid Fleming, Noriyuki Nagahara, Sophia Havaki, Vassilis G. Gorgoulis, Dimitris Thanos, Charalambos Antoniades, Csaba Szabo, Andreas Papapetropoulos
J Exp Med. 2022 Jul 4; 219(7): e20211894. Published online 2022 May 26. doi: 10.1084/jem.20211894
PMCID:
PMC9143789
AbstractArticlePDF–7.5M
6.
Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase
Maria Peleli, Sofia-Iris Bibli, Zhen Li, Athanasia Chatzianastasiou, Aimilia Varela, Antonia Katsouda, Sven Zukunft, Mariarosaria Bucci, Valentina Vellecco, Constantinos H. Davos, Noriyuki Nagahara, Giuseppe Cirino, Ingrid Fleming, David J. Lefer, Andreas Papapetropoulos
Biochem Pharmacol. Author manuscript; available in PMC 2020 Nov 11.
Published in final edited form as: Biochem Pharmacol. 2020 Jun; 176: 113833. Published online 2020 Feb 4. doi: 10.1016/j.bcp.2020.113833
PMCID:
PMC7657663
AbstractArticlePDF–2.4M
7.
Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation and Cellular Bioenergetics in Human Down Syndrome Fibroblasts
Theodora Panagaki, Elisa B. Randi, Csaba Szabo
Biomolecules. 2020 Apr; 10(4): 653. Published online 2020 Apr 23. doi: 10.3390/biom10040653
PMCID:
PMC7226246
AbstractArticlePDF–1.9M
8.
Thioredoxin regulates human mercaptopyruvate sulfurtransferase at physiologically-relevant concentrations
Pramod Kumar Yadav, Victor Vitvitsky, Sebastián Carballal, Javier Seravalli, Ruma Banerjee
J Biol Chem. 2020 May 8; 295(19): 6299–6311. Published online 2020 Mar 16. doi: 10.1074/jbc.RA120.012616
PMCID:
PMC7212645
AbstractArticlePDF–1.8M
9.
Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics in Murine Colon Cancer Cells
Fiona Augsburger, Elisa B. Randi, Mathieu Jendly, Kelly Ascencao, Nahzli Dilek, Csaba Szabo
Biomolecules. 2020 Mar; 10(3): 447. Published online 2020 Mar 13. doi: 10.3390/biom10030447
PMCID:
PMC7175125
AbstractArticlePDF–3.1M
10.
The protective role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H2S) pathway against experimental osteoarthritis
Sonia Nasi, Driss Ehirchiou, Athanasia Chatzianastasiou, Noriyuki Nagahara, Andreas Papapetropoulos, Jessica Bertrand, Giuseppe Cirino, Alexander So, Nathalie Busso
Arthritis Res Ther. 2020; 22: 49. Published online 2020 Mar 17. doi: 10.1186/s13075-020-02147-6
PMCID:
PMC7077027
AbstractArticlePDF–2.7M
11.
Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria
Noriyuki Akahoshi, Tatsuro Minakawa, Masashi Miyashita, Uran Sugiyama, Chihiro Saito, Rintaro Takemoto, Akihiro Honda, Waka Kamichatani, Shotaro Kamata, Yasumi Anan, Isao Ishii
Int J Mol Sci. 2020 Feb; 21(3): 818. Published online 2020 Jan 27. doi: 10.3390/ijms21030818
PMCID:
PMC7038117
AbstractArticlePDF–1.9M
12.
Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology
Masayuki Ide, Tetsuo Ohnishi, Manabu Toyoshima, Shabeesh Balan, Motoko Maekawa, Chie Shimamoto‐Mitsuyama, Yoshimi Iwayama, Hisako Ohba, Akiko Watanabe, Takashi Ishii, Norihiro Shibuya, Yuka Kimura, Yasuko Hisano, Yui Murata, Tomonori Hara, Momo Morikawa, Kenji Hashimoto, Yayoi Nozaki, Tomoko Toyota, Yuina Wada, Yosuke Tanaka, Tadafumi Kato, Akinori Nishi, Shigeyoshi Fujisawa, Hideyuki Okano, Masanari Itokawa, Nobutaka Hirokawa, Yasuto Kunii, Akiyoshi Kakita, Hirooki Yabe, Kazuya Iwamoto, Kohji Meno, Takuya Katagiri, Brian Dean, Kazuhiko Uchida, Hideo Kimura, Takeo Yoshikawa
EMBO Mol Med. 2019 Dec; 11(12): e10695. Published online 2019 Oct 28. doi: 10.15252/emmm.201910695
PMCID:
PMC6895609
AbstractArticlePDF–2.5M
13.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
14.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
15.
Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide
Kenjiro Hanaoka, Kiyoshi Sasakura, Yusuke Suwanai, Sachiko Toma-Fukai, Kazuhito Shimamoto, Yoko Takano, Norihiro Shibuya, Takuya Terai, Toru Komatsu, Tasuku Ueno, Yuki Ogasawara, Yukihiro Tsuchiya, Yasuo Watanabe, Hideo Kimura, Chao Wang, Masanobu Uchiyama, Hirotatsu Kojima, Takayoshi Okabe, Yasuteru Urano, Toshiyuki Shimizu, Tetsuo Nagano
Sci Rep. 2017; 7: 40227. Published online 2017 Jan 12. doi: 10.1038/srep40227
PMCID:
PMC5228037
AbstractArticlePDF–1.2M
16.
Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase
Akbar Ahmad, Domokos Gerö, Gabor Olah, Csaba Szabo
Int J Mol Med. 2016 Dec; 38(6): 1683–1692. Published online 2016 Oct 14. doi: 10.3892/ijmm.2016.2771
PMCID:
PMC5117757
AbstractArticlePDF–1.0M
17.
MPST but not CSE is the primary regulator of hydrogen sulfide production and function in the coronary artery
Maggie M. Kuo, Dae Hee Kim, Sandeep Jandu, Yehudit Bergman, Siqi Tan, Huilei Wang, Deepesh R. Pandey, Theodore P. Abraham, Artin A. Shoukas, Dan E. Berkowitz, Lakshmi Santhanam
Am J Physiol Heart Circ Physiol. 2016 Jan 1; 310(1): H71–H79. Published online 2015 Oct 30. doi: 10.1152/ajpheart.00574.2014
PMCID:
PMC4796461
AbstractArticle
18.
Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain
Yuka Kimura, Yukiko Toyofuku, Shin Koike, Norihiro Shibuya, Noriyuki Nagahara, David Lefer, Yuki Ogasawara, Hideo Kimura
Sci Rep. 2015; 5: 14774. Published online 2015 Oct 6. doi: 10.1038/srep14774
PMCID:
PMC4594004
AbstractArticlePDF–1.1M
19.
Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria
Noriyuki Nagahara, Masatoshi Nagano, Takaaki Ito, Kenji Shimamura, Toshio Akimoto, Hidenori Suzuki
Sci Rep. 2013; 3: 1986. Published online 2013 Jun 13. doi: 10.1038/srep01986
PMCID:
PMC3680806
AbstractArticlePDF–1.4M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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