PMC Links for GEO Profiles (Select 4478026) - PMC

Xiaolin Sun, Chaorui Guo, Chunyan Huang, Ning Lv, Huili Chen, Haoyan Huang, Yulin Zhao, Shanliang Sun, Di Zhao, Jingwei Tian, Xijing Chen, Yongjie Zhang

Redox Biol. 2024 May; 71: 103116. Published online 2024 Mar 6. doi: 10.1016/j.redox.2024.103116

PMCID:: PMC10945259

Abstract Article PDF–16M

Select item 107559705.

KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance

Anastasia-Maria Zavitsanou, Ray Pillai, Yuan Hao, Warren L. Wu, Eric Bartnicki, Triantafyllia Karakousi, Sahith Rajalingam, Alberto Herrera, Angeliki Karatza, Ali Rashidfarrokhi, Sabrina Solis, Metamia Ciampricotti, Anna H. Yeaton, Ellie Ivanova, Corrin A. Wohlhieter, Terkild B. Buus, Makiko Hayashi, Burcu Karadal-Ferrena, Harvey I. Pass, John T. Poirier, Charles M. Rudin, Kwok-Kin Wong, Andre L. Moreira, Kamal M. Khanna, Aristotelis Tsirigos, Thales Papagiannakopoulos, Sergei B. Koralov

Cell Rep. Author manuscript; available in PMC 2023 Dec 29.

Published in final edited form as: Cell Rep. 2023 Nov 28; 42(11): 113295. Published online 2023 Oct 26. doi: 10.1016/j.celrep.2023.113295

PMCID:: PMC10755970

Abstract Article PDF–2.3M

Select item 107465176.

Transcriptomic profiling of the response to excess iodide in Keap1 hypomorphic mice reveals new gene-environment interactions in thyroid homeostasis

Panos G. Ziros, Dionysios V. Chartoumpekis, Ilias Georgakopoulos-Soares, Georgios Psarias, Gerasimos P. Sykiotis

Redox Biol. 2024 Feb; 69: 102978. Published online 2023 Dec 1. doi: 10.1016/j.redox.2023.102978

PMCID:: PMC10746517

Abstract Article PDF–6.5M

Select item 105871417.

Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2

Xinying Ye, Takashi Toyama, Keiko Taguchi, Kotoko Arisawa, Takayuki Kaneko, Ryouhei Tsutsumi, Masayuki Yamamoto, Yoshiro Saito

Commun Biol. 2023; 6: 1060. Published online 2023 Oct 19. doi: 10.1038/s42003-023-05449-y

PMCID:: PMC10587141

Abstract Article PDF–1.8M

Select item 105582178.

Curculigoside mitigates dextran sulfate sodium-induced colitis by activation of KEAP1-NRF2 interaction to inhibit oxidative damage and autophagy of intestinal epithelium barrier

Fang Li, Hua Huang, Ping Zhao, Jie Jiang, Xufeng Ding, Donxgue Lu, Lijiang Ji

Int J Mol Med. 2023 Nov; 52(5): 107. Published online 2023 Sep 28. doi: 10.3892/ijmm.2023.5310

PMCID:: PMC10558217

Abstract Article PDF–10M

Select item 105423859.

FGF18 alleviates hepatic ischemia-reperfusion injury via the USP16-mediated KEAP1/Nrf2 signaling pathway in male mice

Gaozan Tong, Yiming Chen, Xixi Chen, Junfu Fan, Kunxuan Zhu, ZiJing Hu, Santie Li, Junjie Zhu, Jianjun Feng, Zhaohang Wu, Zhenyu Hu, Bin Zhou, Litai Jin, Hui Chen, Jingling Shen, Weitao Cong, XiaoKun Li

Nat Commun. 2023; 14: 6107. Published online 2023 Sep 30. doi: 10.1038/s41467-023-41800-x

PMCID:: PMC10542385

Abstract Article PDF–8.4M

Select item 1050315910.

MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands

Man Zhou, Herman W. Barkema, Jian Gao, Jingyue Yang, Yue Wang, John P. Kastelic, Sohrab Khan, Gang Liu, Bo Han

Vet Res. 2023; 54: 78. Published online 2023 Sep 14. doi: 10.1186/s13567-023-01206-5

PMCID:: PMC10503159

Abstract Article PDF–5.0M

Select item 1048764011.

Forced Hepatic Expression of NRF2 or NQO1 Impedes Hepatocyte Lipid Accumulation in a Lipodystrophy Mouse Model

Nobunao Wakabayashi, Yoko Yagishita, Tanvi Joshi, Thomas W. Kensler

Int J Mol Sci. 2023 Sep; 24(17): 13345. Published online 2023 Aug 28. doi: 10.3390/ijms241713345

PMCID:: PMC10487640

Abstract Article PDF–5.0M

Select item 1045832112.

A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells

Liam Baird, Keiko Taguchi, Anqi Zhang, Yushi Takahashi, Takafumi Suzuki, Thomas W. Kensler, Masayuki Yamamoto

Redox Biol. 2023 Oct; 66: 102845. Published online 2023 Aug 10. doi: 10.1016/j.redox.2023.102845

PMCID:: PMC10458321

Abstract Article PDF–9.7M

Select item 1035314713.

A Point Mutation at C151 of Keap1 of Mice Abrogates NRF2 Signaling, Cytoprotection in Vitro, and Hepatoprotection in Vivo by Bardoxolone Methyl (CDDO-Me)

Tonibelle Gatbonton-Schwager, Yoko Yagishita, Tanvi Joshi, Nobunao Wakabayashi, Harini Srinivasan, Takafumi Suzuki, Masayuki Yamamoto, Thomas W. Kensler

Mol Pharmacol. 2023 Aug; 104(2): 51–61. Published online 2023 Aug. doi: 10.1124/molpharm.123.000671

PMCID:: PMC10353147

Abstract Article PDF–1.7M

Select item 1028208714.

USP25 regulates KEAP1-NRF2 anti-oxidation axis and its inactivation protects acetaminophen-induced liver injury in male mice

Changzhou Cai, Huailu Ma, Jin Peng, Xiang Shen, Xinghua Zhen, Chaohui Yu, Pumin Zhang, Feng Ji, Jiewei Wang

Nat Commun. 2023; 14: 3648. Published online 2023 Jun 20. doi: 10.1038/s41467-023-39412-6

PMCID:: PMC10282087

Abstract Article PDF–2.8M

Select item 1026767915.

Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression

Janine M. DeBlasi, Aimee Falzone, Samantha Caldwell, Nicolas Prieto-Farigua, Justin R. Prigge, Edward E. Schmidt, Iok In Christine Chio, Florian A. Karreth, Gina M. DeNicola

Cancer Res. 2023 Jun 15; 83(12): 1953–1967. Published online 2023 Apr 16. doi: 10.1158/0008-5472.CAN-22-3848

PMCID:: PMC10267679

Abstract Article PDF–43M

Select item 1005340316.

Git1-PGK1 interaction achieves self-protection against spinal cord ischemia-reperfusion injury by modulating Keap1/Nrf2 signaling

Tao Xu, Peng Gao, Yifan Huang, Mengyuan Wu, Jiang Yi, Zheng Zhou, Xuan Zhao, Tao Jiang, Hao Liu, Tao Qin, Zhenqi Yang, Xiaowei Wang, Tianyi Bao, Jian Chen, Shujie Zhao, Guoyong Yin

Redox Biol. 2023 Jun; 62: 102682. Published online 2023 Mar 20. doi: 10.1016/j.redox.2023.102682

PMCID:: PMC10053403

Abstract Article PDF–12M

Select item 999930217.

Celastrol targeting Nedd4 reduces Nrf2-mediated oxidative stress in astrocytes after ischemic stroke

Zexuan Hong, Jun Cao, Dandan Liu, Maozhu Liu, Mengyuan Chen, Fanning Zeng, Zaisheng Qin, Jigang Wang, Tao Tao

J Pharm Anal. 2023 Feb; 13(2): 156–169. Published online 2023 Jan 7. doi: 10.1016/j.jpha.2022.12.002

PMCID:: PMC9999302

Abstract Article PDF–5.5M

Select item 967289318.

Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium

Wataru Hirose, Makoto Horiuchi, Donghan Li, Ikuko N. Motoike, Lin Zhang, Hafumi Nishi, Yusuke Taniyama, Takashi Kamei, Mikiko Suzuki, Kengo Kinoshita, Fumiki Katsuoka, Keiko Taguchi, Masayuki Yamamoto

Cell Mol Gastroenterol Hepatol. 2023; 15(1): 153–178. Published online 2022 Sep 15. doi: 10.1016/j.jcmgh.2022.09.004

PMCID:: PMC9672893

Abstract Article PDF–11M

Select item 961846819.

Nrf2 induces malignant transformation of hepatic progenitor cells by inducing β-catenin expression

Athanassios Fragoulis, Julia Schenkel, Nicole Schröder, Elisa Fabiana Brandt, Mathias Weiand, Tabita Neu, Pierluigi Ramadori, Tim Caspers, Sebastian Kant, Thomas Pufe, Antje Mohs, Christian Trautwein, Thomas Longerich, Konrad Ludwig Streetz, Christoph Jan Wruck

Redox Biol. 2022 Nov; 57: 102453. Published online 2022 Sep 13. doi: 10.1016/j.redox.2022.102453

PMCID:: PMC9618468

Abstract Article PDF–18M

Select item 958873620.

Exploring the Target Scope of KEAP1 E3 Ligase-based PROTACs

Guangyan Du, Jie Jiang, Nathaniel J. Henning, Nozhat Safaee, Eriko Koide, Radosław P. Nowak, Katherine A. Donovan, Hojong Yoon, Inchul You, Hong Yue, Nicholas A. Eleuteri, Zhixiang He, Zhengnian Li, Hubert T. Huang, Jianwei Che, Behnam Nabet, Tinghu Zhang, Eric S. Fischer, Nathanael S. Gray

Cell Chem Biol. Author manuscript; available in PMC 2023 Oct 20.

Published in final edited form as: Cell Chem Biol. 2022 Oct 20; 29(10): 1470–1481.e31. Published online 2022 Sep 6. doi: 10.1016/j.chembiol.2022.08.003

PMCID:: PMC9588736

Abstract Article PDF–2.6M

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