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Items: 1 to 20 of 28

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
3.
Genome-scale CRISPR screen identifies TMEM41B as a multi-function host factor required for coronavirus replication
Limeng Sun, Changzhi Zhao, Zhen Fu, Yanan Fu, Zhelin Su, Yangyang Li, Yuan Zhou, Yubei Tan, Jingjin Li, Yixin Xiang, Xiongwei Nie, Jinfu Zhang, Fei Liu, Shuhong Zhao, Shengsong Xie, Guiqing Peng
PLoS Pathog. 2021 Dec; 17(12): e1010113. Published online 2021 Dec 6. doi: 10.1371/journal.ppat.1010113
PMCID:
PMC8675922
AbstractArticlePDF–5.8M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
6.
NCB5OR Deficiency in the Cerebellum and Midbrain Leads to Dehydration and Alterations in Thirst Response, Fasted Feeding Behavior, and Voluntary Exercise in Mice
Matthew A. Stroh, Michelle K. Winter, Kenneth E. McCarson, John P. Thyfault, Hao Zhu
Cerebellum. Author manuscript; available in PMC 2020 May 15.
Published in final edited form as: Cerebellum. 2018 Apr; 17(2): 152–164. doi: 10.1007/s12311-017-0880-7
PMCID:
PMC7226917
AbstractArticlePDF–814K
7.
Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy
Christian M. Simon, Meaghan Van Alstyne, Francesco Lotti, Elena Bianchetti, Sarah Tisdale, D. Martin Watterson, George Z. Mentis, Livio Pellizzoni
Cell Rep. Author manuscript; available in PMC 2020 Jan 13.
Published in final edited form as: Cell Rep. 2019 Dec 17; 29(12): 3885–3901.e5. doi: 10.1016/j.celrep.2019.11.058
PMCID:
PMC6956708
AbstractArticlePDF–1.6M
8.
Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development
Meaghan Van Alstyne, Francesco Lotti, Andrea Dal Mas, Estela Area Gomez, Livio Pellizzoni
Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Nov 30.
Published in final edited form as: Biochem Biophys Res Commun. 2018 Nov 30; 506(3): 463–470. Published online 2018 Oct 22. doi: 10.1016/j.bbrc.2018.10.073
PMCID:
PMC6242727
AbstractArticlePDF–910K
9.
Loss of NCB5OR in the cerebellum disturbs iron pathways, potentiates behavioral abnormalities, and exacerbates harmaline-induced tremor in mice
Matthew A. Stroh, Michelle K. Winter, Russell H. Swerdlow, Kenneth E. McCarson, Hao Zhu
Metab Brain Dis. Author manuscript; available in PMC 2018 May 1.
Published in final edited form as: Metab Brain Dis. 2016 Aug; 31(4): 951–964. Published online 2016 May 18. doi: 10.1007/s11011-016-9834-x
PMCID:
PMC5929129
AbstractArticlePDF–944K
10.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
11.
A SMN-Dependent U12 Splicing Event Essential for Motor Circuit Function
Francesco Lotti, Wendy L. Imlach, Luciano Saieva, Erin S. Beck, Le T. Hao, Darrick K. Li, Wei Jiao, George Z. Mentis, Christine E. Beattie, Brian D. McCabe, Livio Pellizzoni
Cell. Author manuscript; available in PMC 2013 Oct 12.
Published in final edited form as: Cell. 2012 Oct 12; 151(2): 440–454. doi: 10.1016/j.cell.2012.09.012
PMCID:
PMC3474596
AbstractArticlePDF–3.8M
12.
Development of Diabetes in Lean Ncb5or-Null Mice is Associated with Manifestations of Endoplasmic Reticulum and Oxidative Stress in Beta Cells
WenFang Wang, Ying Guo, Ming Xu, Han-Hung Huang, Lesya Novikova, Kevin Larade, Zhi-Gang Jiang, Terri C. Thayer, Jennifer R. Frontera, Daniel Aires, Helin Ding, John Turk, Clayton E. Mathews, H. Franklin Bunn, Lisa Stehno-Bittel, Hao Zhu
Biochim Biophys Acta. Author manuscript; available in PMC 2012 Nov 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Nov; 1812(11): 1532–1541. Published online 2011 Aug 2. doi: 10.1016/j.bbadis.2011.07.016
PMCID:
PMC3185181
AbstractArticlePDF–1.5M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
Ncb5or Deficiency Increases Fatty Acid Catabolism and Oxidative Stress
Ming Xu, WenFang Wang, Jennifer R. Frontera, Melanie C. Neely, Jianghua Lu, Daniel Aires, Fong-Fu Hsu, John Turk, Russell H. Swerdlow, Susan E. Carlson, Hao Zhu
J Biol Chem. 2011 Apr 1; 286(13): 11141–11154. Published online 2011 Feb 7. doi: 10.1074/jbc.M110.196543
PMCID:
PMC3064168
AbstractArticlePDF–3.5M
15.
NCB5OR Is a Novel Soluble NAD(P)H Reductase Localized in the Endoplasmic Reticulum
Hao Zhu, Kevin Larade, Timothy A. Jackson, Jianxin Xie, Annie Ladoux, Helmut Acker, Utta Berchner-Pfannschmidt, Joachim Fandrey, Andrew R. Cross, Gudrun S. Lukat-Rodgers, Kenton R. Rodgers, H. Franklin Bunn
J Biol Chem. Author manuscript; available in PMC 2011 Feb 27.
Published in final edited form as: J Biol Chem. 2004 Jul 16; 279(29): 30316–30325. Published online 2004 May 6. doi: 10.1074/jbc.M402664200
PMCID:
PMC3045664
AbstractArticlePDF–718K
16.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
17.
Study of the Individual Cytochrome b5 and Cytochrome b5 Reductase Domains of Ncb5or Reveals a Unique Heme Pocket and a Possible Role of the CS Domain
Bin Deng, Sudharsan Parthasarathy, WenFang Wang, Brian R. Gibney, Kevin P. Battaile, Scott Lovell, David R. Benson, Hao Zhu
J Biol Chem. 2010 Sep 24; 285(39): 30181–30191. Published online 2010 Jul 14. doi: 10.1074/jbc.M110.120329
PMCID:
PMC2943328
AbstractArticlePDF–1.8M
18.
The flavoheme reductase Ncb5or protects cells against endoplasmic reticulum stress-induced lipotoxicity
Yongzhao Zhang, Kevin Larade, Zhi-gang Jiang, Susumu Ito, WenFang Wang, Hao Zhu, H. Franklin Bunn
J Lipid Res. 2010 Jan; 51(1): 53–62. doi: 10.1194/jlr.M900146-JLR200
PMCID:
PMC2789786
AbstractArticlePDF–1.5M
19.
Loss of Ncb5or Results in Impaired Fatty Acid Desaturation, Lipoatrophy, and Diabetes
Kevin Larade, Zhigang Jiang, Yongzhao Zhang, WenFang Wang, Susan Bonner-Weir, Hao Zhu, H. Franklin Bunn
J Biol Chem. 2008 Oct 24; 283(43): 29285–29291. doi: 10.1074/jbc.M804645200
PMCID:
PMC2570878
AbstractArticlePDF–534K
20.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K

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