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Select item 101036781.

Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions

He-Wei Jiang, Hong Chen, Yun-Xiao Zheng, Xue-Ning Wang, Qingfeng Meng, Jin Xie, Jiong Zhang, ChangSheng Zhang, Zhao-Wei Xu, Zi-Qing Chen, Lei Wang, Wei-Sha Kong, Kuan Zhou, Ming-Liang Ma, Hai-Nan Zhang, Shu-Juan Guo, Jun-Biao Xue, Jing-Li Hou, Zhe-Yi Liu, Wen-Xue Niu, Fang-Jun Wang, Tao Wang, Wei Li, Rui-Na Wang, Yong-Jun Dang, Daniel M. Czajkowsky, JianFeng Pei, Jia-Jia Dong, Sheng-Ce Tao

Sci China Life Sci. 2023 Apr 14 : 1–19. doi: 10.1007/s11427-023-2316-2 [Epub ahead of print]

PMCID:: PMC10103678

Abstract Article PDF–2.4M

Select item 98316542.

Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice

Wenjie Zhang, Bowen Shi, Shirui Li, Zenglin Liu, Songhan Li, Shuohui Dong, Yugang Cheng, Jiankang Zhu, Guangyong Zhang, Mingwei Zhong

Front Endocrinol (Lausanne) 2022; 13: 1041027. Published online 2022 Dec 27. doi: 10.3389/fendo.2022.1041027

PMCID:: PMC9831654

Abstract Article PDF–25M

Select item 95334863.

Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop

Yongzhen Mo, Yumin Wang, Yian Wang, Xiangying Deng, Qijia Yan, Chunmei Fan, Shuai Zhang, Shanshan Zhang, Zhaojian Gong, Lei Shi, Qianjin Liao, Can Guo, Yong Li, Guiyuan Li, Zhaoyang Zeng, Weihong Jiang, Wei Xiong, Bo Xiang

Mol Cancer. 2022; 21: 192. Published online 2022 Oct 5. doi: 10.1186/s12943-022-01659-w

PMCID:: PMC9533486

Abstract Article PDF–12M

Select item 92781984.

Cloaking the ACE2 receptor with salivary cationic proteins inhibits SARS-CoV-2 entry

Katsutoshi Yoshizato, Toshio Taira, Misako Sato-Matsubara, Shizuko Sekiguchi, Yoriko Yabunaka, Yukimi Kira, Tetsu Ohashi, Atsuko Daikoku, Ken Ofusa, Chiho Kadono, Daisuke Oikawa, Tsutomu Matsubara, Yu Nakagama, Yasutoshi Kido, Fuminori Tokunaga, Kazuo Ikeda, Akira Kaneko, Norifumi Kawada

J Biochem. 2022 Oct; 172(4): 205–216. Published online 2022 Jul 6. doi: 10.1093/jb/mvac054

PMCID:: PMC9278198

Abstract Article PDF–1.5M

Select item 87489585.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 85668086.

Elevated Levels of Neutrophil Activated Proteins, Alpha-Defensins (DEFA1), Calprotectin (S100A8/A9) and Myeloperoxidase (MPO) Are Associated With Disease Severity in COVID-19 Patients

Shubham Shrivastava, Shweta Chelluboina, Prashant Jedge, Purwa Doke, Sonali Palkar, Akhilesh Chandra Mishra, Vidya A. Arankalle

Front Cell Infect Microbiol. 2021; 11: 751232. Published online 2021 Oct 21. doi: 10.3389/fcimb.2021.751232

PMCID:: PMC8566808

Abstract Article PDF–1.2M

Select item 84134797.

Inhibition of SARS-CoV-2 Infection by Human Defensin HNP1 and Retrocyclin RC-101

Elena Kudryashova, Ashley Zani, Geraldine Vilmen, Amit Sharma, Wuyuan Lu, Jacob S. Yount, Dmitri S. Kudryashov

J Mol Biol. 2022 Mar 30; 434(6): 167225. Published online 2021 Sep 3. doi: 10.1016/j.jmb.2021.167225

PMCID:: PMC8413479

Abstract Article PDF–3.2M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78225539.

Alarmin human α defensin HNP1 activates plasmacytoid dendritic cells by triggering NF-κB and IRF1 signaling pathways

Fang Wang, Linan Qiao, Xing Lv, Anna Trivett, Rui Yang, Joost J. Oppenheim, De Yang, Ning Zhang

Cytokine. Author manuscript; available in PMC 2021 Jan 22.

Published in final edited form as: Cytokine. 2016 Jul; 83: 53–60. Published online 2016 Mar 28. doi: 10.1016/j.cyto.2016.03.015

PMCID:: PMC7822553

Abstract Article PDF–858K

Select item 768836110.

Alpha-Defensin versus Leukocyte Esterase in Periprosthetic Joint Infection: An Updated Meta-Analysis

Zhizhuo Li, Qingyu Zhang, Lijun Shi, Fuqiang Gao, Wei Sun, Zirong Li

Biomed Res Int. 2020; 2020: 3704285. Published online 2020 Nov 18. doi: 10.1155/2020/3704285

PMCID:: PMC7688361

Abstract Article PDF–772K

Select item 716998311.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 716465512.

Opposing effects of HNP1 (α-defensin-1) on plasma cholesterol and atherogenesis

Mohamed Higazi, Suhair Abdeen, Rami Abu-Fanne, Samuel N. Heyman, Aseel Masarwy, Khalil Bdeir, Emad Maraga, Douglas B. Cines, Abd Al-Roof Higazi

PLoS One. 2020; 15(4): e0231582. Published online 2020 Apr 17. doi: 10.1371/journal.pone.0231582

PMCID:: PMC7164655

Abstract Article PDF–837K

Select item 657336913.

Fragile X Mental Retardation Protein: Nucleocytoplasmic Shuttling and Association with Somatodendritic Ribosomes

Yue Feng, Claire-Anne Gutekunst, Derek E. Eberhart, Hong Yi, Stephen T. Warren, Steven M. Hersch

J Neurosci. 1997 Mar 1; 17(5): 1539–1547. doi: 10.1523/JNEUROSCI.17-05-01539.1997

PMCID:: PMC6573369

Abstract Article PDF–1.3M

Select item 598731514.

Low-Copy Number Polymorphism in DEFA1/DEFA3 Is Associated with Susceptibility to Hospital-Acquired Infections in Critically Ill Patients

Jialian Zhao, Qiang Gu, Lifeng Wang, Weize Xu, Lihua Chu, Ya Wang, Zhongwang Li, Shuijing Wu, Jianguo Xu, Zhiyong Hu, Qiang Shu, Xiangming Fang

Mediators Inflamm. 2018; 2018: 2152650. Published online 2018 May 22. doi: 10.1155/2018/2152650

PMCID:: PMC5987315

Abstract Article PDF–788K

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 539588316.

PPBP and DEFA1/DEFA3 genes in hyperlipidaemia as feasible synergistic inflammatory biomarkers for coronary heart disease

Yaowapa Maneerat, Kriengchai Prasongsukarn, Surachet Benjathummarak, Wilanee Dechkhajorn

Lipids Health Dis. 2017; 16: 80. Published online 2017 Apr 19. doi: 10.1186/s12944-017-0471-0

PMCID:: PMC5395883

Abstract Article PDF–1.6M

Select item 508109617.

Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation

Javier Barallobre-Barreiro, Shashi K. Gupta, Anna Zoccarato, Rika Kitazume-Taneike, Marika Fava, Xiaoke Yin, Tessa Werner, Marc N Hirt, Anna Zampetaki, Alessandro Viviano, Mei Chong, Marshall Bern, Antonios Kourliouros, Nieves Domenech, Peter Willeit, Ajay M Shah, Marjan Jahangiri, Liliana Schaefer, Jens W. Fischer, Renato V. Iozzo, Rosa Viner, Thomas Thum, Joerg Heineke, Antoine Kichler, Kinya Otsu, Manuel Mayr

Circulation. Author manuscript; available in PMC 2017 Mar 13.

Published in final edited form as: Circulation. 2016 Sep 13; 134(11): 817–832. Published online 2016 Aug 24. doi: 10.1161/CIRCULATIONAHA.115.016423

PMCID:: PMC5081096

Abstract Article PDF–2.5M

Select item 494974618.

Increased alpha-defensin expression is associated with risk of coronary heart disease: a feasible predictive inflammatory biomarker of coronary heart disease in hyperlipidemia patients

Yaowapa Maneerat, Kriengchai Prasongsukarn, Surachet Benjathummarak, Wilanee Dechkhajorn, Urai Chaisri

Lipids Health Dis. 2016; 15: 117. Published online 2016 Jul 18. doi: 10.1186/s12944-016-0285-5

PMCID:: PMC4949746

Abstract Article PDF–1.6M

Select item 494907219.

HP1-assisted Aurora B kinase activity prevents chromosome segregation errors

Yusuke Abe, Kosuke Sako, Kentaro Takagaki, Youko Hirayama, Kazuhiko S.K. Uchida, Jacob A. Herman, Jennifer G. DeLuca, Toru Hirota

Dev Cell. Author manuscript; available in PMC 2017 Mar 7.

Published in final edited form as: Dev Cell. 2016 Mar 7; 36(5): 487–497. doi: 10.1016/j.devcel.2016.02.008

PMCID:: PMC4949072

Abstract Article PDF–1.0M

Select item 493735520.

Human neutrophil peptides inhibit cleavage of von Willebrand factor by ADAMTS13: a potential link of inflammation to TTP

Vikram G. Pillai, Jialing Bao, Catherine B. Zander, Jenny K. McDaniel, Palaniappan S. Chetty, Steven H. Seeholzer, Khalil Bdeir, Douglas B. Cines, X. Long Zheng

Blood. 2016 Jul 7; 128(1): 110–119. Prepublished online 2016 May 13. doi: 10.1182/blood-2015-12-688747

PMCID:: PMC4937355

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