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Select item 86207961.

RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease

Sanjay Awasthi, Ashly Hindle, Neha A. Sawant, Mathew George, Murali Vijayan, Sudhir Kshirsagar, Hallie Morton, Lloyd E. Bunquin, Philip T. Palade, J. Josh Lawrence, Hafiz Khan, Chhanda Bose, P. Hemachandra Reddy, Sharda P. Singh

Cells. 2021 Nov; 10(11): 3113. Published online 2021 Nov 10. doi: 10.3390/cells10113113

PMCID:: PMC8620796

Abstract Article PDF–6.1M

Select item 79387702.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 79376873.

Genetic inactivation of RIP1 kinase does not ameliorate disease in a mouse model of ALS

Sara Dominguez, Eugene Varfolomeev, Robert Brendza, Kim Stark, Joy Tea, Jose Imperio, Hai Ngu, Timothy Earr, Oded Foreman, Joshua D. Webster, Amy Easton, Domagoj Vucic, Baris Bingol

Cell Death Differ. 2021 Mar; 28(3): 915–931. Published online 2020 Sep 29. doi: 10.1038/s41418-020-00625-7

PMCID:: PMC7937687

Abstract Article PDF–4.3M

Select item 63334604.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 58994555.

Rlip depletion prevents spontaneous neoplasia in TP53 null mice

Sanjay Awasthi, Joshua Tompkins, Jyotsana Singhal, Arthur D. Riggs, Sushma Yadav, Xiwei Wu, Sharda Singh, Charles Warden, Zheng Liu, Jinhui Wang, Thomas P. Slavin, Jeffrey N. Weitzel, Yate-Ching Yuan, Meenakshi Awasthi, Satish K. Srivastava, Yogesh C. Awasthi, Sharad S. Singhal

Proc Natl Acad Sci U S A. 2018 Apr 10; 115(15): 3918–3923. Published online 2018 Mar 23. doi: 10.1073/pnas.1719586115

PMCID:: PMC5899455

Abstract Article PDF–883K

Select item 46444386.

RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes

Jeremy G.T. Wurtzel, Seunghyung Lee, Sharad S. Singhal, Sanjay Awasthi, Mark H. Ginsberg, Lawrence E. Goldfinger

Biochem Biophys Res Commun. Author manuscript; available in PMC 2016 Nov 27.

Published in final edited form as: Biochem Biophys Res Commun. 2015 Nov 27; 467(4): 785–791. Published online 2015 Oct 20. doi: 10.1016/j.bbrc.2015.10.064

PMCID:: PMC4644438

Abstract Article PDF–994K

Select item 45214137.

Caspase-8 and c-FLIP_L Associate in Lipid Rafts with NF-κB Adaptors during T Cell Activation

Ravi S. Misra, Jennifer Q. Russell, Andreas Koenig, Jennifer A. Hinshaw-Makepeace, Renren Wen, Demin Wang, Hairong Huo, Dan R. Littman, Uta Ferch, Jurgen Ruland, Margot Thome, Ralph C. Budd

J Biol Chem. Author manuscript; available in PMC 2015 Jul 31.

Published in final edited form as: J Biol Chem. 2007 Jul 6; 282(27): 19365–19374. Published online 2007 Apr 26. doi: 10.1074/jbc.M610610200

PMCID:: PMC4521413

Abstract Article PDF–1009K

Select item 42546188.

The RLIP76 N-terminus binds ARNO to regulate PI 3-kinase, Arf6 and Rac signaling, cell spreading and migration

Seunghyung Lee, Jeremy G.T. Wurtzel, Lawrence E. Goldfinger

Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Nov 28.

Published in final edited form as: Biochem Biophys Res Commun. 2014 Oct 30; 454(4): 560–565. Published online 2014 Oct 30. doi: 10.1016/j.bbrc.2014.10.114

PMCID:: PMC4254618

Abstract Article PDF–769K

Select item 37435089.

RLIP76 Protein Knockdown Attenuates Obesity Due to a High-fat Diet

Sharad S. Singhal, James Figarola, Jyotsana Singhal, Marpadga A. Reddy, Xueli Liu, David Berz, Rama Natarajan, Sanjay Awasthi

J Biol Chem. 2013 Aug 9; 288(32): 23394–23406. Published online 2013 Jul 2. doi: 10.1074/jbc.M113.480194

PMCID:: PMC3743508

Abstract Article PDF–5.6M

Select item 357241010.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 347309011.

RALBP1/RLIP76 depletion in mice suppresses tumor growth by inhibiting tumor neovascularization

Seunghyung Lee, Jeremy G.T. Wurtzel, Sharad S. Singhal, Sanjay Awasthi, Lawrence E. Goldfinger

Cancer Res. Author manuscript; available in PMC 2013 Oct 15.

Published in final edited form as: Cancer Res. 2012 Oct 15; 72(20): 5165–5173. Published online 2012 Aug 17. doi: 10.1158/0008-5472.CAN-12-0468

PMCID:: PMC3473090

Abstract Article PDF–927K

Select item 331799112.

RLIP76 Regulates PI3K/Akt Signaling and Chemo-Radiotherapy Resistance in Pancreatic Cancer

Kathryn Leake, Jyotsana Singhal, Lokesh Dalasanur Nagaprashantha, Sanjay Awasthi, Sharad S. Singhal

PLoS One. 2012; 7(4): e34582. Published online 2012 Apr 3. doi: 10.1371/journal.pone.0034582

PMCID:: PMC3317991

Abstract Article PDF–2.6M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317228814.

RLIP76, a Glutathione-Conjugate Transporter, Plays a Major Role in the Pathogenesis of Metabolic Syndrome

Jyotsana Singhal, Lokesh Nagaprashantha, Rit Vatsyayan, Sanjay Awasthi, Sharad S. Singhal

PLoS One. 2011; 6(9): e24688. Published online 2011 Sep 13. doi: 10.1371/journal.pone.0024688

PMCID:: PMC3172288

Abstract Article PDF–819K

Select item 316571615.

Requirement of FADD, NEMO, and BAX/BAK for Aberrant Mitochondrial Function in Tumor Necrosis Factor Alpha-Induced Necrosis

Krishna M. Irrinki, Karthik Mallilankaraman, Roshan J. Thapa, Harish C. Chandramoorthy, Frank J. Smith, Neelakshi R. Jog, Rajesh Kumar Gandhirajan, Steven G. Kelsen, Steven R. Houser, Michael J. May, Siddharth Balachandran, Muniswamy Madesh

Mol Cell Biol. 2011 Sep; 31(18): 3745–3758. doi: 10.1128/MCB.05303-11

PMCID:: PMC3165716

Abstract Article PDF–4.5M

Select item 306577816.

Glutathione-Conjugate Transport by RLIP76 is required for Clathrin-Dependent Endocytosis and Chemical Carcinogenesis

Sharad S. Singhal, Dilki Wickramarachchi, Sushma Yadav, Jyotsana Singhal, Kathryn Leake, Rit Vatsyayan, Pankaj Chaudhary, Poorna Lelsani, Sumihiro Suzuki, Shaohua Yang, Yogesh C. Awasthi, Sanjay Awasthi

Mol Cancer Ther. Author manuscript; available in PMC 2012 Jan 1.

Published in final edited form as: Mol Cancer Ther. 2011 Jan; 10(1): 16–28. doi: 10.1158/1535-7163.MCT-10-0699

PMCID:: PMC3065778

Abstract Article PDF–2.5M

Select item 306577717.

RLIP76 Transports Sunitinib and Sorafenib and Mediates Drug Resistance in Kidney Cancer

Sharad S. Singhal, Archana Sehrawat, Mukesh Sahu, Preeti Singhal, Rit Vatsyayan, Poorna Chandra Rao Lelsani, Sushma Yadav, Sanjay Awasthi

Int J Cancer. Author manuscript; available in PMC 2011 Mar 29.

Published in final edited form as: Int J Cancer. 2010 Mar 15; 126(6): 1327–1338. doi: 10.1002/ijc.24767

PMCID:: PMC3065777

Abstract Article PDF–582K

Select item 291668218.

Mitogenic and drug-resistance mediating effects of PKCα require RLIP76

Sharad S. Singhal, Sushma Yadav, Jyotsana Singhal, Yogesh C. Awasthi, Sanjay Awasthi

Biochem Biophys Res Commun. Author manuscript; available in PMC 2010 Aug 5.

Published in final edited form as: Biochem Biophys Res Commun. 2006 Sep 22; 348(2): 722–727. Published online 2006 Jul 28. doi: 10.1016/j.bbrc.2006.07.118

PMCID:: PMC2916682

Abstract Article PDF–1.1M

Select item 282864519.

A Central Role of RLIP76 in Regulation of Glycemic Control

Sanjay Awasthi, Sharad S. Singhal, Sushma Yadav, Jyotsana Singhal, Rit Vatsyayan, Ewa Zajac, Rafal Luchowski, Jozef Borvak, Karol Gryczynski, Yogesh C. Awasthi

Diabetes. 2010 Mar; 59(3): 714–725. Published online 2009 Dec 10. doi: 10.2337/db09-0911

PMCID:: PMC2828645

Abstract Article PDF–1.2M

Select item 273053020.

Regulated RalBP1 Binding to RalA and PSD-95 Controls AMPA Receptor Endocytosis and LTD

Kihoon Han, Myoung-Hwan Kim, Daniel Seeburg, Jinsoo Seo, Chiara Verpelli, Seungnam Han, Hye Sun Chung, Jaewon Ko, Hyun Woo Lee, Karam Kim, Won Do Heo, Tobias Meyer, Hyun Kim, Carlo Sala, Se-Young Choi, Morgan Sheng, Eunjoon Kim

PLoS Biol. 2009 Sep; 7(9): e1000187. Published online 2009 Sep 8. doi: 10.1371/journal.pbio.1000187

PMCID:: PMC2730530

Abstract Article PDF–1.6M

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