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Items: 1 to 20 of 93

1.
T-BET and EOMES sustain mature human NK cell identity and antitumor function
Pamela Wong, Jennifer A. Foltz, Lily Chang, Carly C. Neal, Tony Yao, Celia C. Cubitt, Jennifer Tran, Samantha Kersting-Schadek, Sathvik Palakurty, Natalia Jaeger, David A. Russler-Germain, Nancy D. Marin, Margery Gang, Julia A. Wagner, Alice Y. Zhou, Miriam T. Jacobs, Mark Foster, Timothy Schappe, Lynne Marsala, Ethan McClain, Patrick Pence, Michelle Becker-Hapak, Bryan Fisk, Allegra A. Petti, Obi L. Griffith, Malachi Griffith, Melissa M. Berrien-Elliott, Todd A. Fehniger
J Clin Invest. 2023 Jul 3; 133(13): e162530. Published online 2023 Jul 3. doi: 10.1172/JCI162530
PMCID:
PMC10313375
AbstractArticlePDF–13M
2.
The Th1 cell regulatory circuitry is largely conserved between human and mouse
Stephen Henderson, Venu Pullabhatla, Arnulf Hertweck, Emanuele de Rinaldis, Javier Herrero, Graham M Lord, Richard G Jenner
Life Sci Alliance. 2021 Nov; 4(11): e202101075. Published online 2021 Sep 16. doi: 10.26508/lsa.202101075
PMCID:
PMC8960437
AbstractArticlePDF–2.6M
3.
Transcription Factor Protein Interactomes Reveal Genetic Determinants in Heart Disease
Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, Reuben Thomas, Desmond Richmond-Buccola, Ruth Hüttenhain, Krishna Choudhary, Elisabetta Moroni, Mauro W. Costa, Yu Huang, Arun Padmanabhan, Michael Alexanian, Clara Youngna Lee, Bonnie E. J. Maven, Kaitlen Samse-Knapp, Sarah U. Morton, Michael McGregor, Casey A. Gifford, J. G. Seidman, Christine E. Seidman, Bruce D. Gelb, Giorgio Colombo, Bruce R. Conklin, Brian L. Black, Benoit G. Bruneau, Nevan J. Krogan, Katherine S. Pollard, Deepak Srivastava
Cell. Author manuscript; available in PMC 2023 Mar 3.
Published in final edited form as: Cell. 2022 Mar 3; 185(5): 794–814.e30. Published online 2022 Feb 18. doi: 10.1016/j.cell.2022.01.021
PMCID:
PMC8923057
AbstractArticlePDF–2.5M
4.
SARS-CoV-2 spike-specific memory B cells express higher levels of T-bet and FcRL5 after non-severe COVID-19 as compared to severe disease
Raphael A. Reyes, Kathleen Clarke, S. Jake Gonzales, Angelene M. Cantwell, Rolando Garza, Gabriel Catano, Robin E. Tragus, Thomas F. Patterson, Sebastiaan Bol, Evelien M. Bunnik
PLoS One. 2021; 16(12): e0261656. Published online 2021 Dec 22. doi: 10.1371/journal.pone.0261656
PMCID:
PMC8694470
AbstractArticlePDF–3.1M
5.
T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells
Laura Kiekens, Wouter Van Loocke, Sylvie Taveirne, Sigrid Wahlen, Eva Persyn, Els Van Ammel, Zenzi De Vos, Patrick Matthys, Filip Van Nieuwerburgh, Tom Taghon, Pieter Van Vlierberghe, Bart Vandekerckhove, Georges Leclercq
Front Immunol. 2021; 12: 732511. Published online 2021 Sep 24. doi: 10.3389/fimmu.2021.732511
PMCID:
PMC8497824
AbstractArticlePDF–4.2M
6.
High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency
Rui Yang, Marc Weisshaar, Federico Mele, Ibtihal Benhsaien, Karim Dorgham, Jing Han, Carys A. Croft, Samuele Notarbartolo, Jérémie Rosain, Paul Bastard, Anne Puel, Bernhard Fleckenstein, Laurie H. Glimcher, James P. Di Santo, Cindy S. Ma, Guy Gorochov, Aziz Bousfiha, Laurent Abel, Stuart G. Tangye, Jean-Laurent Casanova, Jacinta Bustamante, Federica Sallusto
J Exp Med. 2021 Aug 2; 218(8): e20202726. Published online 2021 Jun 23. doi: 10.1084/jem.20202726
PMCID:
PMC8225679
AbstractArticlePDF–6.2M
7.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
8.
Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation
James W. Austin, Clarisa M. Buckner, Lela Kardava, Wei Wang, Xiaozhen Zhang, Valerie A. Melson, Ryan G. Swanson, Andrew J. Martins, Julian Q. Zhou, Kenneth B. Hoehn, J. Nicholas Fisk, Yiannis Dimopoulos, Alexander Chassiakos, Sijy O’Dell, Margery G. Smelkinson, Catherine A. Seamon, Richard W. Kwan, Michael C. Sneller, Stefania Pittaluga, Nicole A. Doria-Rose, Adrian McDermott, Yuxing Li, Tae-Wook Chun, Steven H. Kleinstein, John S. Tsang, Constantinos Petrovas, Susan Moir
Sci Transl Med. Author manuscript; available in PMC 2020 Sep 9.
Published in final edited form as: Sci Transl Med. 2019 Nov 27; 11(520): eaax0904. doi: 10.1126/scitranslmed.aax0904
PMCID:
PMC7479651
AbstractArticlePDF–3.2M
9.
T-bet Expression in Peripheral Th17.0 Cells Is Associated With Pulmonary Function Changes in Sarcoidosis
Nicholas K. Arger, Siddharth Machiraju, Isabel E. Allen, Prescott G. Woodruff, Laura L. Koth
Front Immunol. 2020; 11: 1129. Published online 2020 Jul 22. doi: 10.3389/fimmu.2020.01129
PMCID:
PMC7387715
AbstractArticlePDF–5.6M
10.
Tbet Expression in Regulatory T Cells Is Required to Initiate Th1-Mediated Colitis
Martina Di Giovangiulio, Angelamaria Rizzo, Eleonora Franzè, Flavio Caprioli, Federica Facciotti, Sara Onali, Agnese Favale, Carmine Stolfi, Hans-Joerg Fehling, Giovanni Monteleone, Massimo C. Fantini
Front Immunol. 2019; 10: 2158. Published online 2019 Sep 11. doi: 10.3389/fimmu.2019.02158
PMCID:
PMC6749075
AbstractArticlePDF–3.7M
11.
T-bet+ lymphocytes infiltration as an independent better prognostic indicator for triple-negative breast cancer
Hitomi Mori, Makoto Kubo, Masaya Kai, Mai Yamada, Kanako Kurata, Hitomi Kawaji, Kazuhisa Kaneshiro, Tomofumi Osako, Reiki Nishimura, Nobuyuki Arima, Masayuki Okido, Junji Kishimoto, Yoshinao Oda, Masafumi Nakamura
Breast Cancer Res Treat. 2019; 176(3): 569–577. Published online 2019 May 8. doi: 10.1007/s10549-019-05256-2
PMCID:
PMC6586701
AbstractArticlePDF–1.5M
12.
Downregulation of Transcription Factor T-Bet as a Protective Strategy in Monosodium Urate-Induced Gouty Inflammation
Qi-Bin Yang, Yong-Long He, Quan-Bo Zhang, Qing-Sheng Mi, Jing-Guo Zhou
Front Immunol. 2019; 10: 1199. Published online 2019 May 29. doi: 10.3389/fimmu.2019.01199
PMCID:
PMC6558421
AbstractArticlePDF–7.7M
13.
B-cell abnormalities in HIV-1 infection: roles for IgG3 and T-bet
Lela Kardava, Susan Moir
Curr Opin HIV AIDS. Author manuscript; available in PMC 2020 Jul 1.
Published in final edited form as: Curr Opin HIV AIDS. 2019 Jul; 14(4): 240–245. doi: 10.1097/COH.0000000000000547
PMCID:
PMC6542707
AbstractArticlePDF–691K
14.
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression
Yu Cao, Jimena Trillo-Tinoco, Rosa A. Sierra, Carmen Anadon, Wenjie Dai, Eslam Mohamed, Ling Cen, Tara L. Costich, Anthony Magliocco, Douglas Marchion, Richard Klar, Sven Michel, Frank Jaschinski, Richard R. Reich, Shikhar Mehrotra, Juan R. Cubillos-Ruiz, David H. Munn, Jose R. Conejo-Garcia, Paulo C. Rodriguez
Nat Commun. 2019; 10: 1280. Published online 2019 Mar 20. doi: 10.1038/s41467-019-09263-1
Correction in:
Nat Commun. 2019; 10: 3680.
PMCID:
PMC6426975
AbstractArticlePDF–3.4M
15.
Three inflammation‐related genes could predict risk in prognosis and metastasis of patients with breast cancer
Shuangtao Zhao, Wenzhi Shen, Renle Du, Xiaohe Luo, Jiangyong Yu, Wei Zhou, Xiaoli Dong, Ruifang Gao, Chaobin Wang, Houpu Yang, Shu Wang
Cancer Med. 2019 Feb; 8(2): 593–605. Published online 2019 Jan 11. doi: 10.1002/cam4.1962
PMCID:
PMC6382731
AbstractArticlePDF–1.1M
16.
Characterization of eomesodermin and T‐bet expression by allostimulated CD8+ T cells of healthy volunteers and kidney transplant patients in relation to graft outcome
A. Perez‐Gutierrez, D. M. Metes, L. Lu, S. Hariharan, A. W. Thomson, M. B. Ezzelarab
Clin Exp Immunol. 2018 Nov; 194(2): 259–272. Published online 2018 Sep 23. doi: 10.1111/cei.13162
PMCID:
PMC6194331
AbstractArticlePDF–1.2M
17.
Signals that drive T-bet expression in B cells
Arpita Myles, Patricia J. Gearhart, Michael P. Cancro
Cell Immunol. Author manuscript; available in PMC 2018 Oct 17.
Published in final edited form as: Cell Immunol. 2017 Nov; 321: 3–7. Published online 2017 Sep 11. doi: 10.1016/j.cellimm.2017.09.004
PMCID:
PMC6191851
AbstractArticlePDF–424K
18.
Clinical Remission of Sight-Threatening Non-Infectious Uveitis Is Characterized by an Upregulation of Peripheral T-Regulatory Cell Polarized Towards T-bet and TIGIT
Rose M. Gilbert, Xiaozhe Zhang, Robert D. Sampson, Michael R. Ehrenstein, Dao X. Nguyen, Mahid Chaudhry, Charles Mein, Nadiya Mahmud, Grazyna Galatowicz, Oren Tomkins-Netzer, Virginia L. Calder, Sue Lightman
Front Immunol. 2018; 9: 907. Published online 2018 May 3. doi: 10.3389/fimmu.2018.00907
PMCID:
PMC5943505
AbstractArticlePDF–3.4M
19.
TBX21 predicts prognosis of patients and drives cancer stem cell maintenance via the TBX21–IL-4 pathway in lung adenocarcinoma
Shuangtao Zhao, Wenzhi Shen, Jiangyong Yu, Luhua Wang
Stem Cell Res Ther. 2018; 9: 89. Published online 2018 Apr 3. doi: 10.1186/s13287-018-0820-6
PMCID:
PMC5883886
AbstractArticlePDF–3.1M
20.
A molecular threshold for effector CD8+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet
Annie Xin, Frederick Masson, Yang Liao, Simon Preston, Tianxia Guan, Renee Gloury, Moshe Olshansky, Jian-Xin Lin, Peng Li, Terence P Speed, Gordon K Smyth, Matthias Ernst, Warren J Leonard, Marc Pellegrini, Susan M Kaech, Stephen L Nutt, Wei Shi, Gabrielle T Belz, Axel Kallies
Nat Immunol. Author manuscript; available in PMC 2018 Jan 23.
Published in final edited form as: Nat Immunol. 2016 Apr; 17(4): 422–432. Published online 2016 Mar 7. doi: 10.1038/ni.3410
PMCID:
PMC5779087
AbstractArticlePDF–1.0M

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