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Select item 114326701.

Glial-Cell-Line-Derived Neurotrophic Factor Promotes Glioblastoma Cell Migration and Invasion via the SMAD2/3-SERPINE1-Signaling Axis

Xiaoxiao Guo, Han Zhou, Yifang Liu, Wei Xu, Kouminin Kanwore, Lin Zhang

Int J Mol Sci. 2024 Sep; 25(18): 10229. Published online 2024 Sep 23. doi: 10.3390/ijms251810229

PMCID:: PMC11432670

Abstract Article PDF–4.2M

Select item 112920012.

GDNF/GFRA1 signaling contributes to chemo- and radioresistance in glioblastoma

Inès C. N. Avenel, Jesper D. Ewald, Jérémy Ariey-Bonnet, Ida H. Kristensen, Stine A. Petterson, Martin N. Thesbjerg, Mark Burton, Mads Thomassen, Krister Wennerberg, Signe R. Michaelsen, Bjarne W. Kristensen

Sci Rep. 2024; 14: 17639. Published online 2024 Jul 31. doi: 10.1038/s41598-024-68626-x

PMCID:: PMC11292001

Abstract Article PDF–1.8M

Select item 110504073.

MicroRNA-Mediated Suppression of Glial Cell Line-Derived Neurotrophic Factor Expression Is Modulated by a Schizophrenia-Associated Non-Coding Polymorphism

Gergely Keszler, Bálint Vékony, Zsuzsanna Elek, Zsófia Nemoda, Nóra Angyal, Zsófia Bánlaki, Réka Kovács-Nagy, Zsolt Rónai, János M. Réthelyi

Int J Mol Sci. 2024 Apr; 25(8): 4477. Published online 2024 Apr 19. doi: 10.3390/ijms25084477

PMCID:: PMC11050407

Abstract Article PDF–1.6M

Select item 109164454.

Distinct serum GDNF coupling with brain structural and functional changes underlies cognitive status in Parkinson's disease

Chuanxi Tang, Ruiao Sun, Ke Xue, Mengying Wang, Sijie Liang, Piniel Alphayo Kambey, Mingyu Shi, Changyu Wu, Gang Chen, Dianshuai Gao

CNS Neurosci Ther. 2024 Mar; 30(3): e14461. Published online 2023 Sep 17. doi: 10.1111/cns.14461

PMCID:: PMC10916445

Abstract Article PDF–13M

Select item 108374305.

The significance of glial cell line-derived neurotrophic factor analysis in Progressive Supranuclear Palsy

Piotr Alster, Dagmara Otto-Ślusarczyk, Stanisław Szlufik, Karolina Duszyńska-Wąs, Agnieszka Drzewińska, Alicja Wiercińska-Drapało, Marta Struga, Michał Kutyłowski, Andrzej Friedman, Natalia Madetko-Alster

Sci Rep. 2024; 14: 2805. Published online 2024 Feb 2. doi: 10.1038/s41598-024-53355-y

PMCID:: PMC10837430

Abstract Article PDF–1.0M

Select item 107059726.

Reduced Levels of Lacrimal Glial Cell Line-Derived Neurotrophic Factor (GDNF) in Patients with Focal Epilepsy and Focal Epilepsy with Comorbid Depression: A Biomarker Candidate

Alexander A. Shpak, Flora K. Rider, Tatiana A. Druzhkova, Marina Y. Zhanina, Sofya B. Popova, Alla B. Guekht, Natalia V. Gulyaeva

Int J Mol Sci. 2023 Dec; 24(23): 16818. Published online 2023 Nov 27. doi: 10.3390/ijms242316818

PMCID:: PMC10705972

Abstract Article PDF–1.6M

Select item 106300827.

Human Neural Progenitors Expressing GDNF Enhance Retinal Protection in a Rodent Model of Retinal Degeneration

Saba Shahin, Patrick Tan, Jason Chetsawang, Bin Lu, Soshana Svendsen, Stephany Ramirez, Trevor Conniff, Jorge S Alfaro, Michael Fernandez, Aaron Fulton, Alexander H Laperle, Clive N Svendsen, Shaomei Wang

Stem Cells Transl Med. 2023 Nov; 12(11): 727–744. Published online 2023 Oct 3. doi: 10.1093/stcltm/szad054

PMCID:: PMC10630082

Abstract Article PDF–64M

Select item 104772508.

Finding an Optimal Level of GDNF Overexpression: Insights from Dopamine Cycling

Pepin Marshall

Cell Mol Neurobiol. 2023; 43(7): 3179–3189. Published online 2023 Jul 6. doi: 10.1007/s10571-023-01375-z

PMCID:: PMC10477250

Abstract Article PDF–2.7M

Select item 101822569.

High Expression of the RET Receptor Tyrosine Kinase and Its Ligand GDNF Identifies a High-Risk Subset of Estrogen Receptor Positive Breast Cancer

Rasha T. Kakati, Hyunsoo Kim, Austin Whitman, Philip M. Spanheimer

Breast Cancer Res Treat. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Breast Cancer Res Treat. 2023 Jun; 199(3): 589–601. Published online 2023 Apr 15. doi: 10.1007/s10549-023-06937-9

PMCID:: PMC10182256

Abstract Article PDF–1.5M

Select item 991266410.

GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1

Brooke A. Marks, Ilissa M. Pipia, Chinatsu Mukai, Sachi Horibata, Edward J. Rice, Charles G. Danko, Scott A. Coonrod

BMC Cancer. 2023; 23: 138. Published online 2023 Feb 10. doi: 10.1186/s12885-023-10559-1

PMCID:: PMC9912664

Abstract Article PDF–1.9M

Select item 977165611.

Overexpression of microRNA-211 in Functional Dyspepsia via Downregulation of the Glial Cell Line-Derived Neurotrophic Factor (GDNF) by Increasing Phosphorylation of p38 MAPK Pathway

Jue Wang, Sai Gu, Bo Qin

Can J Gastroenterol Hepatol. 2022; 2022: 9394381. Published online 2022 Dec 14. doi: 10.1155/2022/9394381

PMCID:: PMC9771656

Abstract Article PDF–1.4M

Select item 943648412.

GDNF regulates lipid metabolism and glioma growth through RET/ERK/HIF-1/SREBP-1

Zhi-Yun Yu, Hong-Jiang Li, Meng Wang, Wen-Zheng Luo, Ya-Ke Xue

Int J Oncol. 2022 Sep; 61(3): 109. Published online 2022 Jul 27. doi: 10.3892/ijo.2022.5399

PMCID:: PMC9436484

Abstract Article PDF–2.2M

Select item 928834213.

Serum Glial Cell Line-Derived Neurotrophic Factor (sGDNF) Is a Novel Biomarker in Predicting Cirrhosis in Patients with Chronic Hepatitis B

Guangyue Yang, Liping Zhuang, Tiantian Sun, Yee Hui Yeo, Le Tao, Wei Zhang, Wenting Ma, Liu Wu, Zongguo Yang, Yanqin Yang, Dongying Xue, Jie Zhang, Rilu Feng, Ebert Matthias P., Steven Dooley, Ekihiro Seki, Ping Liu, Cheng Liu

Can J Gastroenterol Hepatol. 2022; 2022: 1048104. Published online 2022 Jul 9. doi: 10.1155/2022/1048104

PMCID:: PMC9288342

Abstract Article PDF–454K

Select item 858866014.

BDNF, GDNF, NGF and Klotho levels and neurocognitive functions in acute term of schizophrenia

Betul Aslan Turkmen, Esra Yazici, Derya Guzel Erdogan, Mehmet Akif Suda, Ahmet Bulent Yazici

BMC Psychiatry. 2021; 21: 562. Published online 2021 Nov 11. doi: 10.1186/s12888-021-03578-4

PMCID:: PMC8588660

Abstract Article PDF–680K

Select item 846696315.

Human-Specific Regulation of Neurotrophic Factors MANF and CDNF by microRNAs

Julia Konovalova, Dmytro Gerasymchuk, Sergio Navarette Arroyo, Sven Kluske, Francesca Mastroianni, Alba Vargas Pereyra, Andrii Domanskyi

Int J Mol Sci. 2021 Sep; 22(18): 9691. Published online 2021 Sep 7. doi: 10.3390/ijms22189691

PMCID:: PMC8466963

Abstract Article PDF–2.7M

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 791171117.

Glial Cell-Derived Neurotrophic Factor Functions as a Potential Candidate Gene in Obstructive Sleep Apnea Based on a Combination of Bioinformatics and Targeted Capture Sequencing Analyses

Yuanyuan Cao, Qing Zhu, Xintian Cai, Ting Wu, Xiayire Aierken, Ayguzal Ahmat, Shasha Liu, Nanfang Li

Biomed Res Int. 2021; 2021: 6656943. Published online 2021 Feb 18. doi: 10.1155/2021/6656943

PMCID:: PMC7911711

Abstract Article PDF–1.2M

Select item 774556718.

Differentiation of the 50B11 dorsal ganglion cells into NGF and GDNF responsive nociceptor subtypes

Matusica Dusan, Canlas Jastrow, Martin M Alyce, Wei Yingkai, Marri Shashikanth, Erickson Andelain, Barry M Christine, Brierley M Stuart, Best G Oliver, Michael Z Michael, Voelcker H Nicolas, Keating J Damien, Haberberger V Rainer

Mol Pain. 2020; 16: 1744806920970368. Published online 2020 Dec 15. doi: 10.1177/1744806920970368

Correction in:: Mol Pain. 2020; 16: 1744806920987369.

PMCID:: PMC7745567

Abstract Article PDF–1.5M

Select item 757488019.

Acute stress disrupts intestinal homeostasis via GDNF‐RET

Lin Lin, Bingcheng Feng, Ruchen Zhou, Yi Liu, Lixiang Li, Kairuo Wang, Yanbo Yu, Chao Liu, Xin Long, Xiang Gu, Bing Li, Xiaojie Wang, Xiaoyun Yang, Yingzi Cong, Xiuli Zuo, Yanqing Li

Cell Prolif. 2020 Oct; 53(10): e12889. Published online 2020 Aug 17. doi: 10.1111/cpr.12889

PMCID:: PMC7574880

Abstract Article PDF–2.2M

Select item 741579120.

Exosomes derived from GDNF-modified human adipose mesenchymal stem cells ameliorate peritubular capillary loss in tubulointerstitial fibrosis by activating the SIRT1/eNOS signaling pathway

Lu Chen, Yanping Wang, Shulin Li, Bangjie Zuo, Xiangyu Zhang, Fengzhen Wang, Dong Sun

Theranostics. 2020; 10(20): 9425–9442. Published online 2020 Jul 25. doi: 10.7150/thno.43315

PMCID:: PMC7415791

Abstract Article PDF–4.7M

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