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Items: 1 to 20 of 48

1.
Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) and Sudden Infant Death Syndrome: A Potential Model for Investigation
Dénes Tóth, Gábor Simon, Dóra Reglődi
Int J Mol Sci. 2023 Oct; 24(20): 15063. Published online 2023 Oct 11. doi: 10.3390/ijms242015063
PMCID:
PMC10606572
AbstractArticlePDF–1.7M
2.
Calcitonin/PAC1-receptor splice variants: A blindspot in migraine research
Tayla A. Rees, Alejandro Labastida-Ramírez, Eloisa Rubio-Beltrán
Trends Pharmacol Sci. Author manuscript; available in PMC 2024 Oct 1.
Published in final edited form as: Trends Pharmacol Sci. 2023 Oct; 44(10): 651–663. Published online 2023 Aug 3. doi: 10.1016/j.tips.2023.07.003
PMCID:
PMC10529278
AbstractArticlePDF–1.6M
3.
Distribution of PACAP and PAC1 Receptor in the Human Eye
Evelin Patko, Edina Szabo, Denes Toth, Tamas Tornoczky, Inez Bosnyak, Alexandra Vaczy, Tamas Atlasz, Dora Reglodi
J Mol Neurosci. 2022; 72(11): 2176–2187. Published online 2022 Mar 7. doi: 10.1007/s12031-022-01985-0
PMCID:
PMC9726800
AbstractArticlePDF–1.5M
4.
PAC1, VPAC1, and VPAC2 Receptor Expression in Rat and Human Trigeminal Ganglia: Characterization of PACAP-Responsive Receptor Antibodies
Zoe Tasma, Andrew Siow, Paul W. R. Harris, Margaret A. Brimble, Simon J. O’Carroll, Debbie L. Hay, Christopher S. Walker
Int J Mol Sci. 2022 Nov; 23(22): 13797. Published online 2022 Nov 9. doi: 10.3390/ijms232213797
PMCID:
PMC9697343
AbstractArticlePDF–15M
5.
Understanding VPAC receptor family peptide binding and selectivity
Sarah J. Piper, Giuseppe Deganutti, Jessica Lu, Peishen Zhao, Yi-Lynn Liang, Yao Lu, Madeleine M. Fletcher, Mohammed Akhter Hossain, Arthur Christopoulos, Christopher A. Reynolds, Radostin Danev, Patrick M. Sexton, Denise Wootten
Nat Commun. 2022; 13: 7013. Published online 2022 Nov 16. doi: 10.1038/s41467-022-34629-3
PMCID:
PMC9668914
AbstractArticlePDF–5.7M
6.
PACAP-38 and PAC1 Receptor Alterations in Plasma and Cardiac Tissue Samples of Heart Failure Patients
Dóra Szabó, Zsolt Sárszegi, Beáta Polgár, Éva Sághy, Dóra Reglődi, Tünde Tóth, Zsófia Onódi, Przemyslaw Leszek, Zoltán V. Varga, Zsuzsanna Helyes, Ágnes Kemény, Péter Ferdinandy, Andrea Tamás
Int J Mol Sci. 2022 Apr; 23(7): 3715. Published online 2022 Mar 28. doi: 10.3390/ijms23073715
PMCID:
PMC8998504
AbstractArticlePDF–736K
7.
The G protein-coupled receptor PAC1 regulates transactivation of the receptor tyrosine kinase HER3
Terry W. Moody, Lingaku Lee, Robert T. Jensen
J Mol Neurosci. Author manuscript; available in PMC 2022 Aug 1.
Published in final edited form as: J Mol Neurosci. 2021 Aug; 71(8): 1589–1597. Published online 2020 Sep 22. doi: 10.1007/s12031-020-01711-8
PMCID:
PMC8844836
AbstractArticlePDF–1.2M
8.
Impact of ADCYAP1R1 genotype on longitudinal fear conditioning in children: interaction with trauma and sex
Tanja Jovanovic, Anaïs F. Stenson, Nadia Thompson, Aimee Clifford, Alisha Compton, Sean Minton, Sanne J. F. van Rooij, Jennifer S. Stevens, Adriana Lori, Nicole Nugent, Charles F. Gillespie, Bekh Bradley, Kerry J. Ressler
Neuropsychopharmacology. 2020 Sep; 45(10): 1603–1608. Published online 2020 Jun 26. doi: 10.1038/s41386-020-0748-2
PMCID:
PMC7421882
AbstractArticlePDF–606K
9.
Circulating PACAP peptide and PAC1R genotype as possible transdiagnostic biomarkers for anxiety disorders in women: a preliminary study
Rachel A. Ross, Susanne S. Hoeppner, Samantha N. Hellberg, Emily B. O’Day, Peter L. Rosencrans, Kerry J. Ressler, Víctor May, Naomi M. Simon
Neuropsychopharmacology. 2020 Jun; 45(7): 1125–1133. Published online 2020 Jan 7. doi: 10.1038/s41386-020-0604-4
PMCID:
PMC7235237
AbstractArticlePDF–567K
10.
Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism
Jia Wang, Xianqiang Song, Dandan Zhang, Xiaoqing Chen, Xun Li, Yaping Sun, Cui Li, Yunpeng Song, Yao Ding, Ruobing Ren, Essa Hu Harrington, Liaoyuan A. Hu, Wenge Zhong, Cen Xu, Xin Huang, Hong-Wei Wang, Yingli Ma
Cell Res. 2020 May; 30(5): 436–445. Published online 2020 Feb 11. doi: 10.1038/s41422-020-0280-2
Correction in:
Cell Res. 2020 May; 30(5): 455.
PMCID:
PMC7196072
AbstractArticlePDF–3.4M
11.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
12.
PAC1 and PACAP expression, signaling, and effect on the growth of HCT8, human colonic tumor cells
Sang V. Le, Dean J. Yamaguchi, Craig A. McArdle, Ken Tachiki, Joseph R. Pisegna, Patrizia Germano
Regul Pept. Author manuscript; available in PMC 2019 Sep 10.
Published in final edited form as: Regul Pept. 2002 Nov 15; 109(1-3): 115–125. doi: 10.1016/s0167-0115(02)00194-5
PMCID:
PMC6736540
AbstractArticlePDF–630K
13.
Expression of pituitary adenylate cyclase-activating polypeptide and PACAP type 1 receptor in the rat gastric and colonic myenteric neurons
Marcel Miampamba, Patrizia M. Germano, Selin Arli, Helen H. Wong, David Scott, Yvette Taché, Joseph R. Pisegna
Regul Pept. Author manuscript; available in PMC 2019 Sep 10.
Published in final edited form as: Regul Pept. 2002 May 30; 105(3): 145–154. doi: 10.1016/s0167-0115(02)00003-4
PMCID:
PMC6736535
AbstractArticlePDF–1.2M
14.
Pituitary adenylate cyclase activating polypeptide (PACAP), stress and sex hormones
S. Bradley King, Donna J. Toufexis, Sayamwong E. Hammack
Stress. Author manuscript; available in PMC 2019 Sep 4.
Published in final edited form as: Stress. 2017 Sep; 20(5): 465–475. Published online 2017 Jun 14. doi: 10.1080/10253890.2017.1336535
PMCID:
PMC6724739
AbstractArticlePDF–344K
15.
Cloning and Characterization of the Signal Transduction of Four Splice Variants of the Human Pituitary Adenylate Cyclase Activating Polypeptide Receptor: EVIDENCE FOR DUAL COUPLING TO ADENYLATE CYCLASE AND PHOSPHOLIPASE C
Joseph R. Pisegna, Stephen A. Wank
J Biol Chem. Author manuscript; available in PMC 2019 Sep 3.
Published in final edited form as: J Biol Chem. 1996 Jul 19; 271(29): 17267–17274. doi: 10.1074/jbc.271.29.17267
PMCID:
PMC6721843
AbstractArticlePDF–1.0M
16.
Neuroendocrine Tumors Express PAC1 Receptors
SONG N. LIEU, DAVID S. OH, JOSEPH R. PISEGNA, PATRICIA M. GERMANO
Ann N Y Acad Sci. Author manuscript; available in PMC 2019 Sep 3.
Published in final edited form as: Ann N Y Acad Sci. 2006 Jul; 1070: 399–404. doi: 10.1196/annals.1317.052
PMCID:
PMC6719703
AbstractArticlePDF–317K
17.
Differential Coupling of the PAC1 SV1 Splice Variant on Human Colonic Tumors to the Activation of Intracellular cAMP but Not Intracellular Ca2+ Does Not Activate Tumor Proliferation
Patrizia M. Germano, Sang V. Le, David S. Oh, Robert Fan, Sandy Lieu, Alan Siu, Joseph R. Pisegna
J Mol Neurosci. Author manuscript; available in PMC 2019 Aug 23.
Published in final edited form as: J Mol Neurosci. 2004; 22(1-2): 83–92. doi: 10.1385/JMN:22:1-2:83
PMCID:
PMC6707513
AbstractArticlePDF–596K
18.
PAC1R genotype to phenotype correlations in Autism Spectrum Disorder
Meredith Goodrich, Anna Chelsea Armour, Karuna Panchapakesan, Xiaozhen You, Joseph Devaney, Susan Knoblach, Catherine A.W. Sullivan, Maria Jesus Herrero, Abha R. Gupta, Chandan J. Vaidya, Lauren Kenworthy, Joshua G. Corbin
Autism Res. Author manuscript; available in PMC 2019 Jul 30.
Published in final edited form as: Autism Res. 2019 Feb; 12(2): 200–211. Published online 2018 Dec 17. doi: 10.1002/aur.2051
PMCID:
PMC6665682
AbstractArticlePDF–928K
19.
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy
Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115
PMCID:
PMC6077722
AbstractArticlePDF–2.4M
20.
β-Arrestin1 and 2 differentially regulate PACAP-induced PAC1 receptor signaling and trafficking
Yusuke Shintani, Atsuko Hayata-Takano, Keita Moriguchi, Takanobu Nakazawa, Yukio Ago, Atsushi Kasai, Kaoru Seiriki, Norihito Shintani, Hitoshi Hashimoto
PLoS One. 2018; 13(5): e0196946. Published online 2018 May 7. doi: 10.1371/journal.pone.0196946
PMCID:
PMC5937772
AbstractArticlePDF–8.3M

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