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Items: 1 to 20 of 53

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
2.
Context-Specific Stress Causes Compartmentalized SARM1 Activation and Local Degeneration in Cortical Neurons
Flora I. Hinz, Carmela Louise M. Villegas, Jasmine T. Roberts, Heming Yao, Shreya Gaddam, Anton Delwig, Samantha A. Green, Craig Fredrickson, Max Adrian, Raymond R. Asuncion, Tommy K. Cheung, Margaret Hayne, David H. Hackos, Christopher M. Rose, David Richmond, Casper C. Hoogenraad
J Neurosci. 2024 Jun 12; 44(24): e2424232024. Prepublished online 2024 May 1. doi: 10.1523/JNEUROSCI.2424-23.2024
PMCID:
PMC11170950
AbstractArticlePDF–6.8M
3.
SARM1 can be a potential therapeutic target for spinal cord injury
Qicheng Lu, Benson O. A. Botchway, Yong Zhang, Tian Jin, Xuehong Liu
Cell Mol Life Sci. 2022 Mar; 79(3): 161. Published online 2022 Feb 28. doi: 10.1007/s00018-022-04195-4
PMCID:
PMC11072485
AbstractArticlePDF–836K
4.
The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products
Jeremy Garb, Gil Amitai, Allen Lu, Gal Ofir, Alexander Brandis, Tevie Mehlman, Philip J. Kranzusch, Rotem Sorek
PLoS One. 2024; 19(4): e0302251. Published online 2024 Apr 18. doi: 10.1371/journal.pone.0302251
PMCID:
PMC11025887
AbstractArticlePDF–1.0M
5.
A phase transition reduces the threshold for nicotinamide mononucleotide-based activation of SARM1, an NAD(P) hydrolase, to physiologically relevant levels
Janneke Doedée Icso, Paul Ryan Thompson
J Biol Chem. 2023 Nov; 299(11): 105284. Published online 2023 Sep 22. doi: 10.1016/j.jbc.2023.105284
PMCID:
PMC10624580
AbstractArticlePDF–2.3M
6.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
7.
TIR-1/SARM1 inhibits axon regeneration and promotes axon degeneration
Victoria L Czech, Lauren C O'Connor, Brendan Philippon, Emily Norman, Alexandra B Byrne
eLife. 2023; 12: e80856. Published online 2023 Apr 21. doi: 10.7554/eLife.80856
PMCID:
PMC10121217
AbstractArticlePDF–3.0M
8.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson
J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888
PMCID:
PMC9978635
AbstractArticlePDF–10M
9.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
10.
Natural variants of human SARM1 cause both intrinsic and dominant loss-of-function influencing axon survival
Mirlinda Ademi, Xiuna Yang, Michael P. Coleman, Jonathan Gilley
Sci Rep. 2022; 12: 13846. Published online 2022 Aug 16. doi: 10.1038/s41598-022-18052-8
PMCID:
PMC9381744
AbstractArticlePDF–4.2M
11.
TLR4 and SARM1 modulate survival and chemoresistance in an HPV-positive cervical cancer cell line
Mirian Galliote Morale, Rodrigo Esaki Tamura, Ricardo Cintra, Natália Meneses Araújo, Luisa Lina Villa
Sci Rep. 2022; 12: 6714. Published online 2022 Apr 25. doi: 10.1038/s41598-022-09980-6
PMCID:
PMC9039070
AbstractArticlePDF–1.8M
12.
Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients
A. Joseph Bloom, Xianrong Mao, Amy Strickland, Yo Sasaki, Jeffrey Milbrandt, Aaron DiAntonio
Mol Neurodegener. 2022; 17: 1. Published online 2022 Jan 6. doi: 10.1186/s13024-021-00511-x
PMCID:
PMC8739729
AbstractArticlePDF–7.1M
13.
Enrichment of SARM1 alleles encoding variants with constitutively hyperactive NADase in patients with ALS and other motor nerve disorders
Jonathan Gilley, Oscar Jackson, Menelaos Pipis, Mehrdad A Estiar, Ammar Al-Chalabi, Matt C Danzi, Kristel R van Eijk, Stephen A Goutman, Matthew B Harms, Henry Houlden, Alfredo Iacoangeli, Julia Kaye, Leandro Lima, Queen Square Genomics, John Ravits, Guy A Rouleau, Rebecca Schüle, Jishu Xu, Stephan Züchner, Johnathan Cooper-Knock, Ziv Gan-Or, Mary M Reilly, Michael P Coleman
eLife. 2021; 10: e70905. Published online 2021 Nov 19. doi: 10.7554/eLife.70905
PMCID:
PMC8735862
AbstractArticlePDF–3.7M
14.
Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN
Yihang Li, Maria F. Pazyra-Murphy, Daina Avizonis, Mariana de Sá Tavares Russo, Sophia Tang, Chiung-Ya Chen, Yi-Ping Hsueh, Johann S. Bergholz, Tao Jiang, Jean J. Zhao, Jian Zhu, Kwang Woo Ko, Jeffrey Milbrandt, Aaron DiAntonio, Rosalind A. Segal
J Cell Biol. 2022 Feb 7; 221(2): e202106080. Published online 2021 Dec 22. doi: 10.1083/jcb.202106080
PMCID:
PMC8704956
AbstractArticlePDF–6.2M
15.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
Marcel Morgenstern, Christian D. Peikert, Philipp Lübbert, Ida Suppanz, Cinzia Klemm, Oliver Alka, Conny Steiert, Nataliia Naumenko, Alexander Schendzielorz, Laura Melchionda, Wignand W.D. Mühlhäuser, Bettina Knapp, Jakob D. Busch, Sebastian B. Stiller, Stefan Dannenmaier, Caroline Lindau, Mariya Licheva, Christopher Eickhorst, Riccardo Galbusera, Ralf M. Zerbes, Michael T. Ryan, Claudine Kraft, Vera Kozjak-Pavlovic, Friedel Drepper, Sven Dennerlein, Silke Oeljeklaus, Nikolaus Pfanner, Nils Wiedemann, Bettina Warscheid
Cell Metab. 2021 Dec 7; 33(12): 2464–2483.e18. doi: 10.1016/j.cmet.2021.11.001
PMCID:
PMC8664129
AbstractArticle
16.
Expression of sterile-α and armadillo motif containing protein (SARM) in rheumatoid arthritis monocytes correlates with TLR2-induced IL-1β and disease activity
Ryan S Thwaites, Sarah Unterberger, Giselle Chamberlain, Henry Gray, Kelsey Jordan, Kevin A Davies, Neil A Harrison, Sandra Sacre
Rheumatology (Oxford) 2021 Dec; 60(12): 5843–5853. Published online 2021 Feb 19. doi: 10.1093/rheumatology/keab162
PMCID:
PMC8645275
AbstractArticlePDF–603K
17.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
18.
Sarm1-mediated neurodegeneration within the enteric nervous system protects against local inflammation of the colon
Yue Sun, Qi Wang, Yi Wang, Wenran Ren, Ying Cao, Jiali Li, Xin Zhou, Wei Fu, Jing Yang
Protein Cell. 2021 Aug; 12(8): 621–638. Published online 2021 Apr 19. doi: 10.1007/s13238-021-00835-w
PMCID:
PMC8310542
AbstractArticlePDF–3.6M
19.
SARM1 is required in human derived sensory neurons for injury-induced and neurotoxic axon degeneration
Yi-Hsien Chen, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt
Exp Neurol. Author manuscript; available in PMC 2022 May 1.
Published in final edited form as: Exp Neurol. 2021 May; 339: 113636. Published online 2021 Feb 4. doi: 10.1016/j.expneurol.2021.113636
PMCID:
PMC8171232
AbstractArticlePDF–1.9M
20.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M

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