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Select item 111139821.

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10

So Young Lee, Juanma Ramirez, Maribel Franco, Benoît Lectez, Monika Gonzalez, Rosa Barrio, Ugo Mayor

Cell Mol Life Sci. 2014 Jul; 71(14): 2747–2758. Published online 2013 Dec 1. doi: 10.1007/s00018-013-1526-7

PMCID:: PMC11113982

Abstract Article PDF–1.7M

Select item 109457072.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 106700643.

Sustained Nrf2 Overexpression-Induced Metabolic Deregulation Can Be Attenuated by Modulating Insulin/Insulin-like Growth Factor Signaling

Sentiljana Gumeni, Maria Lamprou, Zoi Evangelakou, Maria S. Manola, Ioannis P. Trougakos

Cells. 2023 Nov; 12(22): 2650. Published online 2023 Nov 18. doi: 10.3390/cells12222650

PMCID:: PMC10670064

Abstract Article PDF–2.1M

Select item 103988944.

The E3 ligase Poe promotes Pericentrin degradation

Brian J. Galletta, Ramya Varadarajan, Carey J. Fagerstrom, Bing Yang, Karen Plevock Haase, Katherine McJunkin, Nasser M. Rusan

Mol Biol Cell. 2023 Aug 1; 34(9): br15. Published online 2023 Aug 1. doi: 10.1091/mbc.E22-11-0534

PMCID:: PMC10398894

Abstract Article PDF–4.7M

Select item 102064075.

A global genetic interaction network by single-cell imaging and machine learning

Florian Heigwer, Christian Scheeder, Josephine Bageritz, Schayan Yousefian, Benedikt Rauscher, Christina Laufer, Sergi Beneyto-Calabuig, Maja Christina Funk, Vera Peters, Maria Boulougouri, Jana Bilanovic, Thilo Miersch, Barbara Schmitt, Claudia Blass, Fillip Port, Michael Boutros

Cell Syst. 2023 May 17; 14(5): 346–362.e6. doi: 10.1016/j.cels.2023.03.003

PMCID:: PMC10206407

Abstract Article

Select item 100992876.

Nucleoporins are degraded via upregulation of ESCRT-III/Vps4 complex in Drosophila models of C9-ALS/FTD

Sandeep Kumar Dubey, Kirstin Maulding, Hyun Sung, Thomas E. Lloyd

Cell Rep. Author manuscript; available in PMC 2023 Apr 13.

Published in final edited form as: Cell Rep. 2022 Sep 20; 40(12): 111379. doi: 10.1016/j.celrep.2022.111379

PMCID:: PMC10099287

Abstract Article PDF–3.5M

Select item 93321517.

STABILON, a Novel Sequence Motif That Enhances the Expression and Accumulation of Intracellular and Secreted Proteins

Zsuzsanna Rethi-Nagy, Edit Abraham, Katalin Udvardy, Eva Klement, Zsuzsanna Darula, Margit Pal, Robert L. Katona, Vilmos Tubak, Tibor Pali, Zoltan Kota, Rita Sinka, Andor Udvardy, Zoltan Lipinszki

Int J Mol Sci. 2022 Aug; 23(15): 8168. Published online 2022 Jul 25. doi: 10.3390/ijms23158168

PMCID:: PMC9332151

Abstract Article PDF–3.5M

Select item 87915018.

Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy

Cécile Ribot, Cédric Soler, Aymeric Chartier, Sandy Al Hayek, Rima Naït-Saïdi, Nicolas Barbezier, Olivier Coux, Martine Simonelig

PLoS Genet. 2022 Jan; 18(1): e1010015. Published online 2022 Jan 13. doi: 10.1371/journal.pgen.1010015

PMCID:: PMC8791501

Abstract Article PDF–3.6M

Select item 87005549.

Differential Dose- and Tissue-Dependent Effects of foxo on Aging, Metabolic and Proteostatic Pathways

Maria S. Manola, Sentiljana Gumeni, Ioannis P. Trougakos

Cells. 2021 Dec; 10(12): 3577. Published online 2021 Dec 18. doi: 10.3390/cells10123577

PMCID:: PMC8700554

Abstract Article PDF–17M

Select item 864520710.

In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor

Frederick C. Baker, Hannah Neiswender, Rajalakshmi Veeranan-Karmegam, Graydon B. Gonsalvez

Development. 2021 Nov 15; 148(22): dev199935. Published online 2021 Nov 18. doi: 10.1242/dev.199935

PMCID:: PMC8645207

Abstract Article

Select item 846882711.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 778725812.

Prolonged Exposure to Microgravity Reduces Cardiac Contractility and Initiates Remodeling in Drosophila

Stanley Walls, Soda Diop, Ryan Birse, Lisa Elmen, Zhuohui Gan, Sreehari Kalvakuri, Santiago Pineda, Curran Reddy, Erika Taylor, Bosco Trinh, Georg Vogler, Rachel Zarndt, Andrew McCulloch, Peter Lee, Sharmila Bhattacharya, Rolf Bodmer, Karen Ocorr

Cell Rep. Author manuscript; available in PMC 2021 Jan 6.

Published in final edited form as: Cell Rep. 2020 Dec 8; 33(10): 108445. Published online 2020 Nov 25. doi: 10.1016/j.celrep.2020.108445

PMCID:: PMC7787258

Abstract Article PDF–1.5M

Select item 736935413.

Rpt2 proteasome subunit reduction causes Parkinson's disease like symptoms in Drosophila

Iván Fernández-Cruz, Iván Sánchez-Díaz, Verónica Narváez-Padilla, Enrique Reynaud

IBRO Rep. 2020 Dec; 9: 65–77. Published online 2020 Jul 11. doi: 10.1016/j.ibror.2020.07.001

PMCID:: PMC7369354

Abstract Article PDF–2.8M

Select item 736534614.

Stuxnet Facilitates the Degradation of Polycomb Protein during Development

Juan Du, Junzheng Zhang, Tao He, Yajuan Li, Ying Su, Feng Tie, Min Liu, Peter J. Harte, Alan Jian Zhu

Dev Cell. Author manuscript; available in PMC 2020 Jul 16.

Published in final edited form as: Dev Cell. 2016 Jun 20; 37(6): 507–519. doi: 10.1016/j.devcel.2016.05.013

PMCID:: PMC7365346

Abstract Article PDF–3.2M

Select item 731129515.

Transcriptomic and proteomic profiling of glial versus neuronal Dube3a overexpression reveals common molecular changes in gliopathic epilepsies

Kevin A. Hope, Daniel Johnson, P. Winston Miller, Daniel Lopez-Ferrer, David Kakhniashvili, Lawrence T. Reiter

Neurobiol Dis. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Neurobiol Dis. 2020 Jul; 141: 104879. Published online 2020 Apr 25. doi: 10.1016/j.nbd.2020.104879

PMCID:: PMC7311295

Abstract Article PDF–1.3M

Select item 696157816.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 673554117.

Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

Eleni N. Tsakiri, Sentiljana Gumeni, Konstantinos Vougas, Diana Pendin, Issidora Papassideri, Andrea Daga, Vassilis Gorgoulis, Gábor Juhász, Luca Scorrano, Ioannis P. Trougakos

Autophagy. 2019; 15(10): 1757–1773. Published online 2019 Apr 19. doi: 10.1080/15548627.2019.1596477