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Select item 109102921.

The P granule antibody KT3 recognizes epitopes in both PGL-1 and PGL-3

Brennan M Danlasky, Mario Martinez, Madeline Cassani, Devavrat Bodas, Andrea Putnam, Geraldine Seydoux

MicroPubl Biol. 2024; 2024: 10.17912/micropub.biology.001137. Published online 2024 Feb 16. doi: 10.17912/micropub.biology.001137

PMCID:: PMC10910292

Abstract Article PDF–2.9M

Select item 106176262.

SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans

Valerie J. Robert, Matthieu Caron, Loic Gely, Annie Adrait, Victoria Pakulska, Yohann Couté, Manon Chevalier, Christian G. Riedel, Cecile Bedet, Francesca Palladino

Development. 2023 Nov 1; 150(21): dev201755. Published online 2023 Oct 17. doi: 10.1242/dev.201755

PMCID:: PMC10617626

Abstract Article

Select item 98351503.

Detecting Autophagy in Caenorhabditis elegans Embryos Using Markers of P Granule Degradation

Nicholas J. Palmisano, Alicia Meléndez

Cold Spring Harb Protoc. Author manuscript; available in PMC 2023 Jan 12.

Published in final edited form as: Cold Spring Harb Protoc. 2016 Jan 4; 2016(1): pdb.prot086504. Published online 2016 Jan 4. doi: 10.1101/pdb.prot086504

PMCID:: PMC9835150

Abstract Article PDF–338K

Select item 96337084.

RG/RGG repeats in the C. elegans homologs of Nucleolin and GAR1 contribute to sub-nucleolar phase separation

Emily L. Spaulding, Alexis M. Feidler, Lio A. Cook, Dustin L. Updike

Nat Commun. 2022; 13: 6585. Published online 2022 Nov 3. doi: 10.1038/s41467-022-34225-5

PMCID:: PMC9633708

Abstract Article PDF–6.8M

Select item 94341715.

Large RNP granules in Caenorhabditis elegans oocytes have distinct phases of RNA-binding proteins

Mohamed T Elaswad, Brooklynne M Watkins, Katherine G Sharp, Chloe Munderloh, Jennifer A Schisa

G3 (Bethesda) 2022 Sep; 12(9): jkac173. Published online 2022 Jul 11. doi: 10.1093/g3journal/jkac173

PMCID:: PMC9434171

Abstract Article PDF–1.3M

Select item 93488486.

Maternal H3K36 and H3K27 HMTs protect germline development via regulation of the transcription factor LIN-15B

Chad Steven Cockrum, Susan Strome

eLife. 2022; 11: e77951. Published online 2022 Aug 3. doi: 10.7554/eLife.77951

PMCID:: PMC9348848

Abstract Article PDF–2.7M

Select item 92522847.

DREAM interrupted: severing LIN-35-MuvB association in Caenorhabditis elegans impairs DREAM function but not its chromatin localization

Paul D Goetsch, Susan Strome

Genetics. 2022 Jul; 221(3): iyac073. Published online 2022 May 12. doi: 10.1093/genetics/iyac073

PMCID:: PMC9252284

Abstract Article PDF–1.0M

Select item 86275618.

Regulation of biomolecular condensates by interfacial protein clusters

Andrew W. Folkmann, Andrea Putnam, Chiu Fan Lee, Geraldine Seydoux

Science. Author manuscript; available in PMC 2022 Mar 10.

Published in final edited form as: Science. 2021 Sep 10; 373(6560): 1218–1224. Published online 2021 Sep 9. doi: 10.1126/science.abg7071

PMCID:: PMC8627561

Abstract Article PDF–2.0M

Select item 84493599.

Local thermodynamics govern formation and dissolution of Caenorhabditis elegans P granule condensates

Anatol W. Fritsch, Andrés F. Diaz-Delgadillo, Omar Adame-Arana, Carsten Hoege, Matthäus Mittasch, Moritz Kreysing, Mark Leaver, Anthony A. Hyman, Frank Jülicher, Christoph A. Weber

Proc Natl Acad Sci U S A. 2021 Sep 14; 118(37): e2102772118. Published online 2021 Sep 10. doi: 10.1073/pnas.2102772118

PMCID:: PMC8449359

Abstract Article PDF–1.7M

Select item 833118310.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 823850811.

Protein-based condensation mechanisms drive the assembly of RNA-rich P granules

Helen Schmidt, Andrea Putnam, Dominique Rasoloson, Geraldine Seydoux

eLife. 2021; 10: e63698. Published online 2021 Jun 9. doi: 10.7554/eLife.63698

PMCID:: PMC8238508

Abstract Article PDF–7.3M

Select item 771848012.

Germ Granules Allow Transmission of Small RNA-Based Parental Responses in the “Germ Plasm”

Itamar Lev, Oded Rechavi

iScience. 2020 Dec 18; 23(12): 101831. Published online 2020 Nov 19. doi: 10.1016/j.isci.2020.101831

PMCID:: PMC7718480

Abstract Article PDF–1.1M

Select item 677930913.

The P Granules of C. elegans: A Genetic Model for the Study of RNA–Protein Condensates

Geraldine Seydoux

J Mol Biol. Author manuscript; available in PMC 2019 Nov 2.

Published in final edited form as: J Mol Biol. 2018 Nov 2; 430(23): 4702–4710. Published online 2018 Aug 8. doi: 10.1016/j.jmb.2018.08.007

PMCID:: PMC6779309

Abstract Article PDF–573K

Select item 666892914.

A gel phase promotes condensation of liquid P granules in C. elegans embryos

Andrea Putnam, Madeline Cassani, Jarrett Smith, Geraldine Seydoux

Nat Struct Mol Biol. Author manuscript; available in PMC 2019 Sep 4.

Published in final edited form as: Nat Struct Mol Biol. 2019 Mar; 26(3): 220–226. Published online 2019 Mar 4. doi: 10.1038/s41594-019-0193-2

Correction in:: Nat Struct Mol Biol. 2020 Jan 2

PMCID:: PMC6668929

Abstract Article PDF–1.7M

Select item 653428715.

Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans

Hyemin Min, Yong-Uk Lee, Yhong-Hee Shim, Ichiro Kawasaki

PLoS Genet. 2019 May; 15(5): e1008150. Published online 2019 May 24. doi: 10.1371/journal.pgen.1008150

PMCID:: PMC6534287

Abstract Article PDF–4.7M

Select item 561251516.

The composition of a protein aggregate modulates the specificity and efficiency of its autophagic degradation

Gangming Zhang, Long Lin, Di Qi, Hong Zhang

Autophagy. 2017; 13(9): 1487–1495. Published online 2017 Aug 14. doi: 10.1080/15548627.2017.1339843

PMCID:: PMC5612515

Abstract Article PDF–1.2M

Select item 532559917.

ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans

Karolina M. Andralojc, Anne C. Campbell, Ashley L. Kelly, Markus Terrey, Paige C. Tanner, Ian M. Gans, Michael J. Senter-Zapata, Eraj S. Khokhar, Dustin L. Updike

PLoS Genet. 2017 Feb; 13(2): e1006611. Published online 2017 Feb 9. doi: 10.1371/journal.pgen.1006611

PMCID:: PMC5325599

Abstract Article PDF–5.8M

Select item 503488018.

Polar positioning of phase-separated liquid compartments in cells regulated by an mRNA competition mechanism

Shambaditya Saha, Christoph A. Weber, Marco Nousch, Carsten Hoege, Omar Adame-Arana, Marco Y. Hein, Erin Osborne-Nishimura, Julia Mahamid, Marcus Jahnel, Louise Jawerth, Andrej Pozniakovski, Christian R. Eckmann, Frank Jülicher, Anthony A. Hyman

Cell. Author manuscript; available in PMC 2017 Sep 8.

Published in final edited form as: Cell. 2016 Sep 8; 166(6): 1572–1584.e16. Published online 2016 Sep 1. doi: 10.1016/j.cell.2016.08.006