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Items: 1 to 20 of 22

1.
A drug-like molecule engages nuclear hormone receptor DAF-12/FXR to regulate mitophagy and extend lifespan
Manish Chamoli, Anand Rane, Anna Foulger, Shankar J. Chinta, Azar Asadi Shahmirzadi, Caroline Kumsta, Dhanya K. Nambiar, David Hall, Angelina Holcom, Suzanne Angeli, Minna Schmidt, Sharon Pitteri, Malene Hansen, Gordon J. Lithgow, Julie K. Andersen
Nat Aging. Author manuscript; available in PMC 2024 Jan 19.
Published in final edited form as: Nat Aging. 2023 Dec; 3(12): 1529–1543. Published online 2023 Nov 13. doi: 10.1038/s43587-023-00524-9
PMCID:
PMC10797806
AbstractArticlePDF–3.4M
2.
Peroxiredoxin 2 is required for the redox mediated adaptation to exercise
Qin Xia, Jose C. Casas-Martinez, Eduardo Zarzuela, Javier Muñoz, Antonio Miranda-Vizuete, Katarzyna Goljanek-Whysall, Brian McDonagh
Redox Biol. 2023 Apr; 60: 102631. Published online 2023 Feb 9. doi: 10.1016/j.redox.2023.102631
PMCID:
PMC9950660
AbstractArticlePDF–15M
3.
Cobalt chloride has beneficial effects across species through a hormetic mechanism
Alfonso Schiavi, Alessandra Runci, Teresa Maiorino, Francesco Davide Naso, Marta Barenys, Ellen Fritsche, Flavie Strappazzon, Natascia Ventura
Front Cell Dev Biol. 2022; 10: 986835. Published online 2022 Oct 25. doi: 10.3389/fcell.2022.986835
PMCID:
PMC9642780
AbstractArticlePDF–1.7M
4.
Independent regulation of mitochondrial DNA quantity and quality in Caenorhabditis elegans primordial germ cells
Aaron ZA Schwartz, Nikita Tsyba, Yusuff Abdu, Maulik R Patel, Jeremy Nance
eLife. 2022; 11: e80396. Published online 2022 Oct 6. doi: 10.7554/eLife.80396
Correction in:
eLife. 2023; 12: e93941.
PMCID:
PMC9536838
AbstractArticlePDF–3.7M
5.
Resistance of mitochondrial DNA to cadmium and Aflatoxin B1 damage-induced germline mutation accumulation in C. elegans
Tess C Leuthner, Laura Benzing, Brendan F Kohrn, Christina M Bergemann, Michael J Hipp, Kathleen A Hershberger, Danielle F Mello, Tymofii Sokolskyi, Kevin Stevenson, Ilaria R Merutka, Sarah A Seay, Simon G Gregory, Scott R Kennedy, Joel N Meyer
Nucleic Acids Res. 2022 Aug 26; 50(15): 8626–8642. Published online 2022 Aug 10. doi: 10.1093/nar/gkac666
PMCID:
PMC9410910
AbstractArticlePDF–1.0M
6.
Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in C. elegans
Silvia Maglioni, Alfonso Schiavi, Marlen Melcher, Vanessa Brinkmann, Zhongrui Luo, Anna Laromaine, Nuno Raimundo, Joel N. Meyer, Felix Distelmaier, Natascia Ventura
Nat Commun. 2022; 13: 2620. Published online 2022 May 12. doi: 10.1038/s41467-022-29972-4
PMCID:
PMC9098500
AbstractArticlePDF–2.2M
7.
Allele-specific mitochondrial stress induced by Multiple Mitochondrial Dysfunctions Syndrome 1 pathogenic mutations modeled in Caenorhabditis elegans
Peter A. Kropp, Jing Wu, Michael Reidy, Sanjay Shrestha, Kyle Rhodehouse, Philippa Rogers, Michael N. Sack, Andy Golden
PLoS Genet. 2021 Aug; 17(8): e1009771. Published online 2021 Aug 27. doi: 10.1371/journal.pgen.1009771
PMCID:
PMC8428684
AbstractArticlePDF–3.2M
8.
Molecular Basis of Neuronal Autophagy in Ageing: Insights from Caenorhabditis elegans
Georgios Konstantinidis, Nektarios Tavernarakis
Cells. 2021 Mar; 10(3): 694. Published online 2021 Mar 21. doi: 10.3390/cells10030694
PMCID:
PMC8004021
AbstractArticlePDF–1.0M
9.
NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle
Mario Romani, Vincenzo Sorrentino, Chang-Myung Oh, Hao Li, Tanes Imamura de Lima, Hongbo Zhang, Minho Shong, Johan Auwerx
Cell Rep. 2021 Jan 19; 34(3): 108660. Published online 2021 Jan 19. doi: 10.1016/j.celrep.2020.108660
PMCID:
PMC7816122
AbstractArticle
10.
Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30
Yasmine J. Liu, Rebecca L. McIntyre, Georges E. Janssens, Evan G. Williams, Jiayi Lan, Michel van Weeghel, Bauke Schomakers, Henk van der Veen, Nicole N. van der Wel, Pallas Yao, William B. Mair, Ruedi Aebersold, Alyson W. MacInnes, Riekelt H. Houtkooper
J Cell Biol. 2020 Jun 1; 219(6): e201907067. Published online 2020 Apr 7. doi: 10.1083/jcb.201907067
PMCID:
PMC7265311
AbstractArticlePDF–7.5M
11.
The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress
Terytty Yang Li, Maroun Bou Sleiman, Hao Li, Arwen W. Gao, Adrienne Mottis, Alexis Maximilien Bachmann, Gaby El Alam, Xiaoxu Li, Ludger J. E. Goeminne, Kristina Schoonjans, Johan Auwerx
Nat Aging. Author manuscript; available in PMC 2021 Mar 13.
Published in final edited form as: Nat Aging. 2021 Feb; 1(2): 165–178. Published online 2021 Feb 8. doi: 10.1038/s43587-020-00025-z
PMCID:
PMC7116894
AbstractArticlePDF–6.3M
12.
High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans
Jonathan Alcántar-Fernández, Angélica González-Maciel, Rafael Reynoso-Robles, Martha Elva Pérez Andrade, Alain de J. Hernández-Vázquez, Antonio Velázquez-Arellano, Juan Miranda-Ríos
PLoS One. 2019; 14(12): e0226652. Published online 2019 Dec 17. doi: 10.1371/journal.pone.0226652
PMCID:
PMC6917275
AbstractArticlePDF–3.2M
13.
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
Evandro F. Fang, Yujun Hou, Sofie Lautrup, Martin Borch Jensen, Beimeng Yang, Tanima SenGupta, Domenica Caponio, Rojyar Khezri, Tyler G. Demarest, Yahyah Aman, David Figueroa, Marya Morevati, Ho-Joon Lee, Hisaya Kato, Henok Kassahun, Jong-Hyuk Lee, Deborah Filippelli, Mustafa Nazir Okur, Aswin Mangerich, Deborah L. Croteau, Yoshiro Maezawa, Costas A. Lyssiotis, Jun Tao, Koutaro Yokote, Tor Erik Rusten, Mark P. Mattson, Heinrich Jasper, Hilde Nilsen, Vilhelm A. Bohr
Nat Commun. 2019; 10: 5284. Published online 2019 Nov 21. doi: 10.1038/s41467-019-13172-8
PMCID:
PMC6872719
AbstractArticlePDF–3.7M
14.
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
Evandro F. Fang, Yujun Hou, Konstantinos Palikaras, Bryan A. Adriaanse, Jesse S. Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan, Paula Rocktäschel, Deborah L. Croteau, Mansour Akbari, Nigel H. Greig, Tormod Fladby, Hilde Nilsen, M. Zameel Cader, Mark P. Mattson, Nektarios Tavernarakis, Vilhelm A. Bohr
Nat Neurosci. Author manuscript; available in PMC 2019 Sep 1.
Published in final edited form as: Nat Neurosci. 2019 Mar; 22(3): 401–412. Published online 2019 Feb 11. doi: 10.1038/s41593-018-0332-9
PMCID:
PMC6693625
AbstractArticlePDF–1.3M
15.
OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes
Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye
Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307
PMCID:
PMC6216590
AbstractArticlePDF–1.4M
16.
Autophagy and Longevity
Shuhei Nakamura, Tamotsu Yoshimori
Mol Cells. 2018 Jan 31; 41(1): 65–72. Published online 2018 Jan 23. doi: 10.14348/molcells.2018.2333
PMCID:
PMC5792715
AbstractArticlePDF–741K
17.
Molecular definitions of autophagy and related processes
Lorenzo Galluzzi, Eric H Baehrecke, Andrea Ballabio, Patricia Boya, José Manuel Bravo‐San Pedro, Francesco Cecconi, Augustine M Choi, Charleen T Chu, Patrice Codogno, Maria Isabel Colombo, Ana Maria Cuervo, Jayanta Debnath, Vojo Deretic, Ivan Dikic, Eeva‐Liisa Eskelinen, Gian Maria Fimia, Simone Fulda, David A Gewirtz, Douglas R Green, Malene Hansen, J Wade Harper, Marja Jäättelä, Terje Johansen, Gabor Juhasz, Alec C Kimmelman, Claudine Kraft, Nicholas T Ktistakis, Sharad Kumar, Beth Levine, Carlos Lopez‐Otin, Frank Madeo, Sascha Martens, Jennifer Martinez, Alicia Melendez, Noboru Mizushima, Christian Münz, Leon O Murphy, Josef M Penninger, Mauro Piacentini, Fulvio Reggiori, David C Rubinsztein, Kevin M Ryan, Laura Santambrogio, Luca Scorrano, Anna Katharina Simon, Hans‐Uwe Simon, Anne Simonsen, Nektarios Tavernarakis, Sharon A Tooze, Tamotsu Yoshimori, Junying Yuan, Zhenyu Yue, Qing Zhong, Guido Kroemer
EMBO J. 2017 Jul 3; 36(13): 1811–1836. Published online 2017 Jun 8. doi: 10.15252/embj.201796697
PMCID:
PMC5494474
AbstractArticlePDF–1.0M
18.
Coupling mitogenesis and mitophagy for longevity
Konstantinos Palikaras, Eirini Lionaki, Nektarios Tavernarakis
Autophagy. 2015 Aug; 11(8): 1428–1430. Published online 2015 Sep 14. doi: 10.1080/15548627.2015.1061172
PMCID:
PMC4590656
AbstractArticlePDF–238K
19.
Interfacing mitochondrial biogenesis and elimination to enhance host pathogen defense and longevity
Konstantinos Palikaras, Eirini Lionaki, Nektarios Tavernarakis
Worm. 2015 Jul-Sep; 4(3): e1071763. Published online 2015 Jul 29. doi: 10.1080/21624054.2015.1071763
PMCID:
PMC4588546
AbstractArticlePDF–403K
20.
Balancing mitochondrial biogenesis and mitophagy to maintain energy metabolism homeostasis
K Palikaras, E Lionaki, N Tavernarakis
Cell Death Differ. 2015 Sep; 22(9): 1399–1401. Published online 2015 Aug 10. doi: 10.1038/cdd.2015.86
PMCID:
PMC4532782
ArticlePDF–558K

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