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Items: 1 to 20 of 76

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
2.
DNA polymerase beta connects tumorigenicity with the circadian clock in liver cancer through the epigenetic demethylation of Per1
Siyu Chen, Wenxiang Zhang, Xiao Li, Zhengyu Cao, Chang Liu
Cell Death Dis. 2024 Jan; 15(1): 78. Published online 2024 Jan 20. doi: 10.1038/s41419-024-06462-7
PMCID:
PMC10799862
AbstractArticlePDF–4.4M
3.
Disrupting Circadian Rhythm via the PER1–HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer
Jiao Wang, Qiong Huang, Xingbin Hu, Shuyi Zhang, Yu Jiang, Guangyu Yao, Kongzhen Hu, Xin Xu, Bishan Liang, Qijing Wu, Zhenfeng Ma, Yawen Wang, Chunlin Wang, Zhenzhen Wu, Xiaoxiang Rong, Wangjun Liao, Min Shi
Cancer Res. 2022 Apr 15; 82(8): 1503–1517. Published online 2022 Mar 7. doi: 10.1158/0008-5472.CAN-21-1820
PMCID:
PMC9662874
AbstractArticlePDF–2.8M
4.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
5.
Association of rs3027178 polymorphism in the circadian clock gene PER1 with susceptibility to Alzheimer’s disease and longevity in an Italian population
Maria Giulia Bacalini, Flavia Palombo, Paolo Garagnani, Cristina Giuliani, Claudio Fiorini, Leonardo Caporali, Michelangelo Stanzani Maserati, Sabina Capellari, Martina Romagnoli, Sara De Fanti, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Daniela Galimberti, Elio Scarpini, Marina Arcaro, Enrica Bonanni, Gabriele Siciliano, Michelangelo Maestri, Biancamaria Guarnieri, Italian Multicentric Group on clock genes, actigraphy in AD, Morena Martucci, Daniela Monti, Valerio Carelli, Claudio Franceschi, Chiara La Morgia, Aurelia Santoro
GeroScience. 2022 Apr; 44(2): 881–896. Published online 2021 Dec 18. doi: 10.1007/s11357-021-00477-0
PMCID:
PMC9135916
AbstractArticlePDF–905K
6.
The promoter hypermethylation of SULT2B1 accelerates esophagus tumorigenesis via downregulated PER1
Zhuo Li, Meng‐Yan Li, Ling‐Ling Wang, Lei Li, Qing‐Yun Chen, Ying‐Hui Zhu, Yan Li, Yan‐ru Qin, Xin‐Yuan Guan
Thorac Cancer. 2021 Dec; 12(24): 3370–3379. Published online 2021 Nov 2. doi: 10.1111/1759-7714.14211
Correction in:
Thorac Cancer. 2022 Sep; 13(18): 2664–2665.
PMCID:
PMC8671905
AbstractArticlePDF–2.0M
7.
A missense variant rs2585405 in clock gene PER1 is associated with the increased risk of noise-induced hearing loss in a Chinese occupational population
Hao Chen, Xuexue Ding, Enmin Ding, Mengyao Chen, Huimin Wang, Guangzhi Yang, Baoli Zhu
BMC Med Genomics. 2021; 14: 221. Published online 2021 Sep 8. doi: 10.1186/s12920-021-01075-x
PMCID:
PMC8425122
AbstractArticlePDF–1017K
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
The Circadian Protein PER1 Modulates the Cellular Response to Anticancer Treatments
Marina Maria Bellet, Claudia Stincardini, Claudio Costantini, Marco Gargaro, Stefania Pieroni, Marilena Castelli, Danilo Piobbico, Paolo Sassone-Corsi, Maria Agnese Della-Fazia, Luigina Romani, Giuseppe Servillo
Int J Mol Sci. 2021 Mar; 22(6): 2974. Published online 2021 Mar 15. doi: 10.3390/ijms22062974
PMCID:
PMC8001324
AbstractArticlePDF–2.0M
10.
PER1 suppresses glycolysis and cell proliferation in oral squamous cell carcinoma via the PER1/RACK1/PI3K signaling complex
Xiaobao Gong, Hong Tang, Kai Yang
Cell Death Dis. 2021 Mar; 12(3): 276. Published online 2021 Mar 15. doi: 10.1038/s41419-021-03563-5
PMCID:
PMC7960720
AbstractArticlePDF–2.4M
11.
BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A
Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng
Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676
PMCID:
PMC7606008
AbstractArticlePDF–2.5M
12.
Period Family of Clock Genes as Novel Predictors of Survival in Human Cancer: A Systematic Review and Meta-Analysis
Fan Deng, Kai Yang, Gang Zheng
Dis Markers. 2020; 2020: 6486238. Published online 2020 Aug 10. doi: 10.1155/2020/6486238
PMCID:
PMC7436287
AbstractArticlePDF–1.1M
13.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
14.
Loss of the clock gene Per1 promotes oral squamous cell carcinoma progression via the AKT/mTOR pathway
Guojun Yang, Yixin Yang, Hong Tang, Kai Yang
Cancer Sci. 2020 May; 111(5): 1542–1554. Published online 2020 Mar 18. doi: 10.1111/cas.14362
PMCID:
PMC7226219
AbstractArticlePDF–3.1M
15.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
16.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
17.
Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets
Kristen Mengwasser, Richard Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D’Andrea, Stephen J. Elledge
Mol Cell. Author manuscript; available in PMC 2019 Dec 4.
Published in final edited form as: Mol Cell. 2019 Mar 7; 73(5): 885–899.e6. Published online 2019 Jan 24. doi: 10.1016/j.molcel.2018.12.008
PMCID:
PMC6892393
AbstractArticlePDF–1.7M
18.
The Per-1 Short Isoform Inhibits de novo HIV-1 Transcription in Resting CD4+ T-cells
Li Zhao, Mei Liu, Jiayue Ouyang, Zheming Zhu, Wenqing Geng, Jinxiu Dong, Ying Xiong, Shumei Wang, Xiaowei Zhang, Ying Qiao, Haibo Ding, Hong Sun, Guoxin Liang, Hong Shang, Xiaoxu Han
Curr HIV Res. 2018 Dec; 16(6): 384–395. Published online 2018 Dec. doi: 10.2174/1570162X17666190218145048
PMCID:
PMC6446521
AbstractArticlePDF–1.8M
19.
Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks
Meng Qu, Tomas Duffy, Tsuyoshi Hirota, Steve A. Kay
Proc Natl Acad Sci U S A. 2018 Dec 26; 115(52): E12305–E12312. Published online 2018 Dec 10. doi: 10.1073/pnas.1816411115
PMCID:
PMC6310821
AbstractArticlePDF–1.1M
20.
The non-classical nuclear import carrier Transportin 1 modulates circadian rhythms through its effect on PER1 nuclear localization
Sandra Korge, Bert Maier, Franziska Brüning, Lea Ehrhardt, Thomas Korte, Matthias Mann, Andreas Herrmann, Maria S. Robles, Achim Kramer
PLoS Genet. 2018 Jan; 14(1): e1007189. Published online 2018 Jan 29. doi: 10.1371/journal.pgen.1007189
PMCID:
PMC5805371
AbstractArticlePDF–6.4M

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