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Items: 1 to 20 of 45

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Nuclear membrane protein SUN2 promotes replication of flaviviruses through modulating cytoskeleton reorganization mediated by NS1
Yanxia Huang, Qinyu Peng, Xu Tian, Cancan Chen, Xuanfeng Zhu, Changbai Huang, Zhiting Huo, Yang Liu, Chao Yang, Chao Liu, Ping Zhang
Nat Commun. 2024; 15: 296. Published online 2024 Jan 5. doi: 10.1038/s41467-023-44580-6
PMCID:
PMC10766649
AbstractArticlePDF–6.9M
3.
SUN1/2 controls macrophage polarization via modulating nuclear size and stiffness
Shi Jiao, Chuanchuan Li, Fenghua Guo, Jinjin Zhang, Hui Zhang, Zhifa Cao, Wenjia Wang, Wenbo Bu, Mobin Lin, Junhong Lü, Zhaocai Zhou
Nat Commun. 2023; 14: 6416. Published online 2023 Oct 12. doi: 10.1038/s41467-023-42187-5
PMCID:
PMC10570371
AbstractArticlePDF–5.0M
4.
Lem2 is essential for cardiac development by maintaining nuclear integrity
Jacob A Ross, Nathaly Arcos-Villacis, Edmund Battey, Cornelis Boogerd, Constanza Avalos Orellana, Emilie Marhuenda, Pamela Swiatlowska, Didier Hodzic, Fabrice Prin, Tim Mohun, Norman Catibog, Olga Tapia, Larry Gerace, Thomas Iskratsch, Ajay M Shah, Matthew J Stroud
Cardiovasc Res. 2023 Aug; 119(11): 2074–2088. Published online 2023 Apr 17. doi: 10.1093/cvr/cvad061
PMCID:
PMC10478753
AbstractArticlePDF–33M
5.
Disulfide bond in SUN2 regulates dynamic remodeling of LINC complexes at the nuclear envelope
Rahul Sharma, Martin W Hetzer
Life Sci Alliance. 2023 Aug; 6(8): e202302031. Published online 2023 May 15. doi: 10.26508/lsa.202302031
PMCID:
PMC10193101
AbstractArticlePDF–3.6M
6.
TRIM27 cooperates with STK38L to inhibit ULK1‐mediated autophagy and promote tumorigenesis
Yi Yang, Yifu Zhu, Shuai Zhou, Peipei Tang, Ran Xu, Yuwei Zhang, Dongping Wei, Jian Wen, Rick F Thorne, Xu Dong Zhang, Jun‐Lin Guan, Lianxin Liu, Mian Wu, Song Chen
EMBO J. 2022 Jul; 41(14): e109777. Published online 2022 Jun 7. doi: 10.15252/embj.2021109777
PMCID:
PMC9289709
AbstractArticlePDF–2.3M
7.
The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation
Emma Carley, Rachel M Stewart, Abigail Zieman, Iman Jalilian, Diane E King, Amanda Zubek, Samantha Lin, Valerie Horsley, Megan C King
eLife. 2021; 10: e58541. Published online 2021 Mar 29. doi: 10.7554/eLife.58541
PMCID:
PMC8051949
AbstractArticlePDF–8.3M
8.
The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization
Andres Ramirez-Martinez, Yichi Zhang, Kenian Chen, Jiwoong Kim, Bercin K. Cenik, John R. McAnally, Chunyu Cai, John M. Shelton, Jian Huang, Ana Brennan, Bret M. Evers, Pradeep P. A. Mammen, Lin Xu, Rhonda Bassel-Duby, Ning Liu, Eric N. Olson
Nat Commun. 2021; 12: 690. Published online 2021 Jan 29. doi: 10.1038/s41467-021-20987-x
PMCID:
PMC7846557
AbstractArticlePDF–2.9M
9.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
10.
SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells
Lauren Porter, Rose-Marie Minaisah, Sultan Ahmed, Seema Ali, Rosemary Norton, Qiuping Zhang, Elisa Ferraro, Chris Molenaar, Mark Holt, Susan Cox, Samuel Fountain, Catherine Shanahan, Derek Warren
Cells. 2020 Jan; 9(1): 132. Published online 2020 Jan 6. doi: 10.3390/cells9010132
PMCID:
PMC7017107
AbstractArticlePDF–3.4M
11.
Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers
Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang
FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R
PMCID:
PMC6993925
AbstractArticle
12.
Ablation of SUN2-containing LINC complexes drives cardiac hypertrophy without interstitial fibrosis
Rachel M. Stewart, Elisa C. Rodriguez, Megan C. King
Mol Biol Cell. 2019 Jul 1; 30(14): 1664–1675. doi: 10.1091/mbc.E18-07-0438
PMCID:
PMC6727752
AbstractArticlePDF–3.0M
13.
A molecular model for LINC complex regulation: activation of SUN2 for KASH binding
Zeinab Jahed, Uyen T. Vu, Darya Fadavi, Huimin Ke, Akshay Rathish, Samuel C.J. Kim, Wei Feng, Mohammad R.K. Mofrad
Mol Biol Cell. 2018 Aug 8; 29(16): 2012–2023. doi: 10.1091/mbc.E18-04-0266
PMCID:
PMC6232973
AbstractArticlePDF–3.0M
14.
Suppression of SUN2 by DNA methylation is associated with HSCs activation and hepatic fibrosis
Xin Chen, Wan-Xia Li, Yu Chen, Xiao-Feng Li, Hai-Di Li, Hui-Min Huang, Fang-Tian Bu, Xue-Yin Pan, Yang Yang, Cheng Huang, Xiao-Ming Meng, Jun Li
Cell Death Dis. 2018 Oct; 9(10): 1021. Published online 2018 Oct 3. doi: 10.1038/s41419-018-1032-9
PMCID:
PMC6170444
AbstractArticlePDF–3.6M
15.
Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells
Petra Gimpel, Yin Loon Lee, Radoslaw M. Sobota, Alessandra Calvi, Victoria Koullourou, Rutti Patel, Kamel Mamchaoui, François Nédélec, Sue Shackleton, Jan Schmoranzer, Brian Burke, Bruno Cadot, Edgar R. Gomes
Curr Biol. 2017 Oct 9; 27(19): 2999–3009.e9. doi: 10.1016/j.cub.2017.08.031
PMCID:
PMC5640514
AbstractArticle
16.
Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle
Matthew J. Stroud, Wei Feng, Jianlin Zhang, Jennifer Veevers, Xi Fang, Larry Gerace, Ju Chen
J Cell Biol. 2017 Jul 3; 216(7): 1915–1924. doi: 10.1083/jcb.201612128
PMCID:
PMC5496623
AbstractArticlePDF–1.9M
17.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
18.
Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments
Hawa-Racine Thiam, Pablo Vargas, Nicolas Carpi, Carolina Lage Crespo, Matthew Raab, Emmanuel Terriac, Megan C. King, Jordan Jacobelli, Arthur S. Alberts, Theresia Stradal, Ana-Maria Lennon-Dumenil, Matthieu Piel
Nat Commun. 2016; 7: 10997. Published online 2016 Mar 15. doi: 10.1038/ncomms10997
PMCID:
PMC4796365
AbstractArticlePDF–2.5M
19.
Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin
Xiaolai Zhou, Lirong Sun, Francisco Bastos de Oliveira, Xiaoyang Qi, William J. Brown, Marcus B. Smolka, Ying Sun, Fenghua Hu
J Cell Biol. 2015 Sep 14; 210(6): 991–1002. doi: 10.1083/jcb.201502029
PMCID:
PMC4576858
AbstractArticlePDF–3.0M
20.
Sun1 deficiency leads to cerebellar ataxia in mice
Jing-Ya Wang, I.-Shing Yu, Chien-Chi Huang, Chia-Yen Chen, Wan-Ping Wang, Shu-Wha Lin, Kuan-Teh Jeang, Ya-Hui Chi
Dis Model Mech. 2015 Aug 1; 8(8): 957–967. doi: 10.1242/dmm.019240
PMCID:
PMC4527285
AbstractArticle

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