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Select item 111510301.

SRSF1 Is Required for Mitochondrial Homeostasis and Thermogenic Function in Brown Adipocytes Through its Control of Ndufs3 Splicing

Ningyang Yuan, Lei Shen, Qian Peng, Rula Sha, Zhenzhen Wang, Zhiqi Xie, Xue You, Ying Feng

Adv Sci (Weinh) 2024 Jun; 11(21): 2306871. Published online 2024 Apr 3. doi: 10.1002/advs.202306871

PMCID:: PMC11151030

Abstract Article PDF–14M

Select item 110720532.

SRSF1 is essential for primary follicle development by regulating granulosa cell survival via mRNA alternative splicing

Xiaohong Yao, Chaofan Wang, Weiran Yu, Longjie Sun, Zheng Lv, Xiaomei Xie, Shuang Tian, Lu Yan, Hua Zhang, Jiali Liu

Cell Mol Life Sci. 2023 Nov; 80(11): 343. Published online 2023 Oct 31. doi: 10.1007/s00018-023-04979-2

PMCID:: PMC11072053

Abstract Article PDF–4.4M

Select item 110174363.

Truncated Dyrk1A aggravates neuronal apoptosis by inhibiting ASF‐mediated Bcl‐x exon 2b inclusion

Shuqiang Zhang, Junjie Zhong, Lian Xu, Yue Wu, Jie Xu, Jianhua Shi, Zhikai Gu, Xiaoyu Li, Nana Jin

CNS Neurosci Ther. 2024 Apr; 30(4): e14493. Published online 2023 Oct 21. doi: 10.1111/cns.14493

PMCID:: PMC11017436

Abstract Article PDF–12M

Select item 109456944.

Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice

Longjie Sun, Zheng Lv, Xuexue Chen, Rong Ye, Shuang Tian, Chaofan Wang, Xiaomei Xie, Lu Yan, Xiaohong Yao, Yujing Shao, Sheng Cui, Juan Chen, Jiali Liu

eLife. 2024; 12: RP89316. Published online 2024 Jan 25. doi: 10.7554/eLife.89316

PMCID:: PMC10945694

Abstract Article PDF–9.5M

Select item 107971985.

Splicing factor SRSF1 controls distinct molecular programs in regulatory and effector T cells implicated in systemic autoimmune disease

Michael F. Cassidy, Zachary T. Herbert, Vaishali R. Moulton

Mol Immunol. Author manuscript; available in PMC 2024 Jan 19.

Published in final edited form as: Mol Immunol. 2022 Jan; 141: 94–103. Published online 2021 Nov 25. doi: 10.1016/j.molimm.2021.11.008

PMCID:: PMC10797198

Abstract Article PDF–974K

Select item 107819666.

Unveiling dysregulated lncRNAs and networks in non-syndromic cleft lip with or without cleft palate pathogenesis

Caihong Wu, Haojie Liu, Zhuorong Zhan, Xinyu Zhang, Mengnan Zhang, Jiawen You, Junqing Ma

Sci Rep. 2024; 14: 1047. Published online 2024 Jan 10. doi: 10.1038/s41598-024-51747-8

PMCID:: PMC10781966

Abstract Article PDF–6.3M

Select item 106028777.

Srsf1 and Elavl1 act antagonistically on neuronal fate choice in the developing neocortex by controlling TrkC receptor isoform expression

A Ioana Weber, Srinivas Parthasarathy, Ekaterina Borisova, Ekaterina Epifanova, Marco Preußner, Alexandra Rusanova, Mateusz C Ambrozkiewicz, Paraskevi Bessa, Andrew G Newman, Lisa Müller, Heiner Schaal, Florian Heyd, Victor Tarabykin

Nucleic Acids Res. 2023 Oct 27; 51(19): 10218–10237. Published online 2023 Sep 11. doi: 10.1093/nar/gkad703

Correction in:: Nucleic Acids Res. 2024 Feb 9; 52(3): 1522.

PMCID:: PMC10602877

Abstract Article PDF–2.5M

Select item 105397088.

SRSF1-mediated alternative splicing is required for spermatogenesis

Wen-Long Lei, Yuan-Yuan Li, Zongchang Du, Ruibao Su, Tie-Gang Meng, Yan Ning, Guanmei Hou, Heide Schatten, Zhen-Bo Wang, Zhiming Han, Fei Sun, Wei-Ping Qian, Chenli Liu, Qing-Yuan Sun

Int J Biol Sci. 2023; 19(15): 4883–4897. Published online 2023 Sep 11. doi: 10.7150/ijbs.83474

PMCID:: PMC10539708

Abstract Article PDF–7.8M

Select item 103300719.

Splicing Factor SRSF1 Promotes Pancreatitis and KRAS^G12D-Mediated Pancreatic Cancer

Ledong Wan, Kuan-Ting Lin, Mohammad Alinoor Rahman, Yuma Ishigami, Zhikai Wang, Mads A. Jensen, John E. Wilkinson, Youngkyu Park, David A. Tuveson, Adrian R. Krainer

Cancer Discov. Author manuscript; available in PMC 2024 Jan 7.

Published in final edited form as: Cancer Discov. 2023 Jul 7; 13(7): 1678–1695. doi: 10.1158/2159-8290.CD-22-1013

PMCID:: PMC10330071

Abstract Article PDF–3.2M

Select item 1030785210.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 999359511.

SRSF1 regulates primordial follicle formation and number determination during meiotic prophase I

Longjie Sun, Zheng Lv, Xuexue Chen, Chaofan Wang, Pengbo Lv, Lu Yan, Shuang Tian, Xiaomei Xie, Xiaohong Yao, Jingjing Liu, Zhao Wang, Haoshu Luo, Sheng Cui, Jiali Liu

BMC Biol. 2023; 21: 49. Published online 2023 Mar 8. doi: 10.1186/s12915-023-01549-7

PMCID:: PMC9993595

Abstract Article PDF–4.6M

Select item 991175912.

Splicing factor SRSF1 deficiency in the liver triggers NASH-like pathology and cell death

Waqar Arif, Bhoomika Mathur, Michael F. Saikali, Ullas V. Chembazhi, Katelyn Toohill, You Jin Song, Qinyu Hao, Saman Karimi, Steven M. Blue, Brian A. Yee, Eric L. Van Nostrand, Sushant Bangru, Grace Guzman, Gene W. Yeo, Kannanganattu V. Prasanth, Sayeepriyadarshini Anakk, Carolyn L. Cummins, Auinash Kalsotra

Nat Commun. 2023; 14: 551. Published online 2023 Feb 9. doi: 10.1038/s41467-023-35932-3

PMCID:: PMC9911759

Abstract Article PDF–3.6M

Select item 960386013.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 952374914.

Splicing factor SRSF1 is essential for CD8 T cell function and host antigen-specific viral immunity

Ignacio Juarez, Shi Su, Zachary T. Herbert, John R. Teijaro, Vaishali R. Moulton

Front Immunol. 2022; 13: 906355. Published online 2022 Sep 16. doi: 10.3389/fimmu.2022.906355

PMCID:: PMC9523749

Abstract Article PDF–16M

Select item 948193315.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 897423616.

SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal

Tingsheng Yu, Oscar Cazares, Alison D. Tang, Hyun-Yi Kim, Tomas Wald, Adya Verma, Qi Liu, Mary Helen Barcellos-Hoff, Stephen N. Floor, Han-Sung Jung, Angela N. Brooks, Ophir D. Klein

Dev Cell. Author manuscript; available in PMC 2023 Mar 14.

Published in final edited form as: Dev Cell. 2022 Mar 14; 57(5): 624–637.e4. Published online 2022 Feb 23. doi: 10.1016/j.devcel.2022.01.011

PMCID:: PMC8974236

Abstract Article PDF–4.2M

Select item 882537117.

SRSF1 Deficiency Impairs the Late Thymocyte Maturation and the CD8 Single-Positive Lineage Fate Decision

Ce Ji, Li Bao, Shunzong Yuan, Zhihong Qi, Fang Wang, Menghao You, Guotao Yu, Jingjing Liu, Xiao Cui, Zhao Wang, Juanjuan Liu, Wenhui Guo, Mingxia Feng, Feng Chen, Youmin Kang, Shuyang Yu

Front Immunol. 2022; 13: 838719. Published online 2022 Jan 26. doi: 10.3389/fimmu.2022.838719

PMCID:: PMC8825371

Abstract Article PDF–6.8M

Select item 874425718.

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins

Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo

BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y

PMCID:: PMC8744257

Abstract Article PDF–6.0M

Select item 854597819.

SRSF1 plays a critical role in invariant natural killer T cell development and function

Jingjing Liu, Menghao You, Yingpeng Yao, Ce Ji, Zhao Wang, Fang Wang, Di Wang, Zhihong Qi, Guotao Yu, Zhen Sun, Wenhui Guo, Juanjuan Liu, Shumin Li, Yipeng Jin, Tianyan Zhao, Hai-Hui Xue, Yuanchao Xue, Shuyang Yu

Cell Mol Immunol. 2021 Nov; 18(11): 2502–2515. Published online 2021 Sep 14. doi: 10.1038/s41423-021-00766-w

PMCID:: PMC8545978

Abstract Article PDF–4.8M

Select item 848125820.

The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF1

Jian Sun, Tongzhu Jin, Wei Su, Yingying Guo, Zhihui Niu, Jiayu Guo, Liangliang Li, Jiayi Wang, Lu Ma, Tong Yu, Xuelian Li, Yuhong Zhou, Hongli Shan, Haihai Liang

Cell Death Differ. 2021 Oct; 28(10): 2916–2930. Published online 2021 May 12. doi: 10.1038/s41418-021-00792-1