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Select item 112394981.

Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1

Allwyn Pereira, Jeisimhan Diwakar, Giacomo Masserdotti, Sude Beşkardeş, Tatiana Simon, Younju So, Lucía Martín-Loarte, Franziska Bergemann, Lakshmy Vasan, Tamas Schauer, Anna Danese, Riccardo Bocchi, Maria Colomé-Tatché, Carol Schuurmans, Anna Philpott, Tobias Straub, Boyan Bonev, Magdalena Götz

Nat Neurosci. 2024; 27(7): 1260–1273. Published online 2024 Jul 2. doi: 10.1038/s41593-024-01677-5

PMCID:: PMC11239498

Abstract Article PDF–37M

Select item 112229492.

Yin Yang 1 regulates cohesin complex protein SMC3 in mouse hematopoietic stem cells

Zhanping Lu, Yinghua Wang, Anna L. F. V. Assumpção, Peng Liu, Audrey Kopp, Sahitya Saka, Sean J. Mcilwain, Aaron D. Viny, Marjorie Brand, Xuan Pan

Blood Adv. 2024 Jun 25; 8(12): 3076–3091. Published online 2024 Mar 28. doi: 10.1182/bloodadvances.2023011411

PMCID:: PMC11222949

Abstract Article PDF–3.9M

Select item 111390543.

The Transcription Factor YY-1 Is an Essential Regulator of T Follicular Helper Cell Differentiation

Simon Bélanger, Sonya Haupt, Brian L. Freeman, Adam J. Getzler, Huitian Diao, Matthew E. Pipkin, Shane Crotty

J Immunol. Author manuscript; available in PMC 2024 May 30.

Published in final edited form as: J Immunol. 2022 Oct 15; 209(8): 1566–1573. Published online 2022 Sep 12. doi: 10.4049/jimmunol.2101176

PMCID:: PMC11139054

Abstract Article PDF–2.0M

Select item 111096194.

YY1 Lactylation Aggravates Autoimmune Uveitis by Enhancing Microglial Functions via Inflammatory Genes

Jiaxing Huang, Xiaotang Wang, Na Li, Wei Fan, Xingran Li, Qian Zhou, Jiangyi Liu, Wanqian Li, Zhi Zhang, Xiaoyan Liu, Shuhao Zeng, Hui Yang, Meng Tian, Peizeng Yang, Shengping Hou

Adv Sci (Weinh) 2024 May; 11(19): 2308031. Published online 2024 Mar 17. doi: 10.1002/advs.202308031

PMCID:: PMC11109619

Abstract Article PDF–12M

Select item 110940095.

YY1 binding is a gene-intrinsic barrier to Xist-mediated gene silencing

Joseph S Bowness, Mafalda Almeida, Tatyana B Nesterova, Neil Brockdorff

EMBO Rep. 2024 May; 25(5): 2258–2277. Published online 2024 Apr 23. doi: 10.1038/s44319-024-00136-3

PMCID:: PMC11094009

Abstract Article PDF–2.4M

Select item 108133556.

MiR-192-5p Ameliorates Hepatic Lipid Metabolism in Non-Alcoholic Fatty Liver Disease by Targeting Yy1

Lina Ma, Huichen Song, Chen-Yu Zhang, Dongxia Hou

Biomolecules. 2024 Jan; 14(1): 34. Published online 2023 Dec 26. doi: 10.3390/biom14010034

PMCID:: PMC10813355

Abstract Article PDF–5.0M

Select item 105298787.

Yin Yang 1 controls cerebellar astrocyte maturation

Karli Mockenhaupt, Katarzyna M. Tyc, Adam McQuiston, Alexandra K. Gonsiewski, Masoumeh Zarei-Kheirabadi, Avani Hariprashad, Debolina D. Biswas, Angela S. Gupta, Amy L. Olex, Sandeep K. Singh, Michael R. Waters, Jeff L. Dupree, Mikhail G. Dozmorov, Tomasz Kordula

Glia. Author manuscript; available in PMC 2024 Oct 1.

Published in final edited form as: Glia. 2023 Oct; 71(10): 2437–2455. Published online 2023 Jul 7. doi: 10.1002/glia.24434

PMCID:: PMC10529878

Abstract Article PDF–4.3M

Select item 104990168.

Dynamic nucleosome remodeling mediated by YY1 underlies early mouse development

Mizuki Sakamoto, Shusaku Abe, Yuka Miki, Yusuke Miyanari, Hiroyuki Sasaki, Takashi Ishiuchi

Genes Dev. 2023 Jul 1; 37(13-14): 590–604. doi: 10.1101/gad.350376.122

PMCID:: PMC10499016

Abstract Article PDF–14M

Select item 103523459.

A renal YY1-KIM1-DR5 axis regulates the progression of acute kidney injury

Chen Yang, Huidie Xu, Dong Yang, Yunhao Xie, Mingrui Xiong, Yu Fan, XiKai Liu, Yu Zhang, Yushuo Xiao, Yuchen Chen, Yihao Zhou, Liangliang Song, Chen Wang, Anlin Peng, Robert B. Petersen, Hong Chen, Kun Huang, Ling Zheng

Nat Commun. 2023; 14: 4261. Published online 2023 Jul 17. doi: 10.1038/s41467-023-40036-z

PMCID:: PMC10352345

Abstract Article PDF–5.2M

Select item 1033036210.

Polycomb group protein CBX7 represses cardiomyocyte proliferation via modulation of the TARDBP/RBM38 axis

Kyu-Won Cho, Mark Andrade, Seongho Bae, Sangsung Kim, Jin Eyun Kim, Er Yearn Jang, Sangho Lee, Ahsan Husain, Roy L. Sutliff, John W. Calvert, Changwon Park, Young-sup Yoon

Circulation. Author manuscript; available in PMC 2024 Jun 13.

Published in final edited form as: Circulation. 2023 Jun 13; 147(24): 1823–1842. Published online 2023 May 9. doi: 10.1161/CIRCULATIONAHA.122.061131

PMCID:: PMC10330362

Abstract Article PDF–1.6M

Select item 1019301411.

Regulation of TREM2 expression by transcription factor YY1 and its protective effect against Alzheimer’s disease

Yanhui Lu, Xiaofeng Huang, Wenping Liang, Yu Li, Mengen Xing, Wenhao Pan, Yun Zhang, Zhe Wang, Weihong Song

J Biol Chem. 2023 May; 299(5): 104688. Published online 2023 Apr 11. doi: 10.1016/j.jbc.2023.104688

PMCID:: PMC10193014

Abstract Article PDF–1.5M

Select item 1015205912.

YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6

Saisai Chen, Kai Lu, Yue Hou, Zonghao You, Chuanjun Shu, Xiaoying Wei, Tiange Wu, Naipeng Shi, Guangyuan Zhang, Jianping Wu, Shuqiu Chen, Lihua Zhang, Wenchao Li, Dingxiao Zhang, Shenghong Ju, Ming Chen, Bin Xu

J Immunother Cancer. 2023; 11(4): e006020. Published online 2023 Apr 24. doi: 10.1136/jitc-2022-006020

PMCID:: PMC10152059

Abstract Article PDF–26M

Select item 1012015613.

YY1 lactylation in microglia promotes angiogenesis through transcription activation-mediated upregulation of FGF2

Xiaotang Wang, Wei Fan, Na Li, Yan Ma, Mudi Yao, Guoqing Wang, Siyuan He, Wanqian Li, Jun Tan, Qi Lu, Shengping Hou

Genome Biol. 2023; 24: 87. Published online 2023 Apr 21. doi: 10.1186/s13059-023-02931-y

PMCID:: PMC10120156

Abstract Article PDF–6.1M

Select item 977753314.

miR-301a Deficiency Attenuates the Macrophage Migration and Phagocytosis through YY1/CXCR4 Pathway

Jiawei Xu, Lanya Fu, Junyao Deng, Jiaqi Zhang, Ying Zou, Liqiang Liao, Xinrui Ma, Zhenlin Li, Yizhou Xu, Yuantao Xu, Shuyi Xu, Jingmin Liu, Xianghai Wang, Xiaodong Ma, Jiasong Guo

Cells. 2022 Dec; 11(24): 3952. Published online 2022 Dec 7. doi: 10.3390/cells11243952

PMCID:: PMC9777533

Abstract Article PDF–3.1M

Select item 977216515.

Astrocytic yin yang 1 (YY1) is critical for murine brain development and protection against apoptosis, oxidative stress, and inflammation

Edward Pajarillo, Ivan Nyarko-Danquah, Alexis Digman, Cynthia Vied, Deok-Soo Son, Jayden Lee, Michael Aschner, Eunsook Lee

Glia. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Glia. 2023 Feb; 71(2): 450–466. Published online 2022 Oct 27. doi: 10.1002/glia.24286

PMCID:: PMC9772165

Abstract Article PDF–2.7M

Select item 975695316.

YY1 safeguard multidimensional epigenetic landscape associated with extended pluripotency

Xiaotao Dong, Rong Guo, Tianrong Ji, Jie Zhang, Jun Xu, Yaoyi Li, Yingliang Sheng, Yuxiang Wang, Ke Fang, Yulin Wen, Bei Liu, Gongcheng Hu, Hongkui Deng, Hongjie Yao

Nucleic Acids Res. 2022 Nov 28; 50(21): 12019–12038. Published online 2022 Apr 15. doi: 10.1093/nar/gkac230