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Select item 112656231.

Intrinsically Disordered Membrane Anchors of Rheb, RhoA, and DiRas3 Small GTPases: Molecular Dynamics, Membrane Organization, and Interactions

Chase M. Hutchins, Alemayehu A. Gorfe

J Phys Chem B. Author manuscript; available in PMC 2024 Jul 23.

Published in final edited form as: J Phys Chem B. 2024 Jul 11; 128(27): 6518–6528. Published online 2024 Jun 28. doi: 10.1021/acs.jpcb.4c01876

PMCID:: PMC11265623

Abstract Article PDF–2.2M

Select item 112148912.

Genetic disruption of ATAT1 causes RhoA downregulation through abnormal truncation of C/EBPβ

Jee-Hye Choi, Jangho Jeong, Jaegu Kim, Eunae You, Seula Keum, Seongeun Song, Ye Eun Hwang, Minjoo Ji, Kwon-Sik Park, Sangmyung Rhee

BMB Rep. 2024 Jun 30; 57(6): 293–298. Published online 2024 May 3. doi: 10.5483/BMBRep.2023-0230

PMCID:: PMC11214891

Abstract Article PDF–3.7M

Select item 112099353.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111600564.

Overexpression of RhoA enhances peritoneal dissemination: RhoA suppression with Lovastatin may be useful for ovarian cancer

Akiko Horiuchi, Norihiko Kikuchi, Ryosuke Osada, Cuiju Wang, Akiko Hayashi, Toshio Nikaido, Ikuo Konishi

Cancer Sci. 2008 Dec; 99(12): 2532–2539. Published online 2008 Nov 24. doi: 10.1111/j.1349-7006.2008.00977.x

PMCID:: PMC11160056

Abstract Article PDF–325K

Select item 111155025.

Celiac disease IgA modulates vascular permeability in vitro through the activity of transglutaminase 2 and RhoA

Essi Myrsky, Sergio Caja, Zsofi Simon-Vecsei, Ilma R. Korponay-Szabo, Cristina Nadalutti, Russell Collighan, Alexandre Mongeot, Martin Griffin, Markku Mäki, Katri Kaukinen, Katri Lindfors

Cell Mol Life Sci. 2009 Oct; 66(20): 3375–3385. Published online 2009 Aug 13. doi: 10.1007/s00018-009-0116-1

PMCID:: PMC11115502

Abstract Article PDF–473K

Select item 111057516.

Transcriptional and post-transcriptional regulation of the genes encoding the small GTPases RhoA, RhoB, and RhoC: implications for the pathogenesis of human diseases

Eirini Nomikou, Melina Livitsanou, Christos Stournaras, Dimitris Kardassis

Cell Mol Life Sci. 2018 Jun; 75(12): 2111–2124. Published online 2018 Mar 2. doi: 10.1007/s00018-018-2787-y

PMCID:: PMC11105751

Abstract Article PDF–1.4M

Select item 109971277.

Hydrostatic pressure mediates epithelial-mesenchymal transition of cholangiocytes through RhoA/ROCK and TGF-β/smad pathways

Mahmoud Osman Khalifa, Chen Yan, Yong Chai, Kosei Ito, Shou-Hua Zhang, Tao-Sheng Li

PLoS One. 2024; 19(4): e0300548. Published online 2024 Apr 5. doi: 10.1371/journal.pone.0300548

PMCID:: PMC10997127

Abstract Article PDF–1.7M

Select item 109902778.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Abstract Article PDF–3.9M

Select item 108670589.

LAMB3 Promotes Myofibrogenesis and Cytoskeletal Reorganization in Endometrial Stromal Cells via the RhoA/ROCK1/MYL9 Pathway

Xiaomei Qin, Bin Zeng, Suren R. Sooranna, Mujun Li

Cell Biochem Biophys. 2024; 82(1): 127–137. Published online 2023 Oct 6. doi: 10.1007/s12013-023-01186-5

PMCID:: PMC10867058

Abstract Article PDF–2.1M

Select item 1082160110.

The Snail signaling branch downstream of the TGF-β/Smad3 pathway mediates Rho activation and subsequent stress fiber formation

Mitsuyoshi Motizuki, Takashi Yokoyama, Masao Saitoh, Keiji Miyazawa

J Biol Chem. 2024 Jan; 300(1): 105580. Published online 2023 Dec 21. doi: 10.1016/j.jbc.2023.105580

PMCID:: PMC10821601

Abstract Article PDF–5.5M

Select item 1081322311.

Lipopolysaccharide Stimulates A549 Cell Migration through p-Tyr 42 RhoA and Phospholipase D1 Activity

Shohel Mahmud, Amir Hamza, Yoon-Beom Lee, Jung-Ki Min, Rokibul Islam, Oyungerel Dogsom, Jae-Bong Park

Biomolecules. 2024 Jan; 14(1): 6. Published online 2023 Dec 20. doi: 10.3390/biom14010006

PMCID:: PMC10813223

Abstract Article PDF–3.1M

Select item 1058999912.

Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles

Shidong Shan, Min Su, Yan Li, Zhen Wang, Daoquan Liu, Yongying Zhou, Xun Fu, Shu Yang, Junchao Zhang, Jizhang Qiu, Huan Liu, Guang Zeng, Ping Chen, Xinghuan Wang, Michael E. DiSanto, Yuming Guo, Xinhua Zhang

Mol Med. 2023; 29: 139. Published online 2023 Oct 20. doi: 10.1186/s10020-023-00734-2

PMCID:: PMC10589999

Abstract Article PDF–11M

Select item 1054146613.

Fidgetin-like 2 depletion enhances cell migration by regulating GEF-H1, RhoA, and FAK

Karishma Smart, Adam H. Kramer, Sachin Smart, Louis Hodgson, David J. Sharp

Biophys J. 2023 Sep 19; 122(18): 3600–3610. Published online 2022 Dec 15. doi: 10.1016/j.bpj.2022.12.018

PMCID:: PMC10541466

Abstract Article PDF–2.5M

Select item 1048053514.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 1044047515.

Some aspects of the life of SARS-CoV-2 ORF3a protein in mammalian cells

Song Jiao, Pablo Miranda, Yan Li, Dragan Maric, Miguel Holmgren

Heliyon. 2023 Aug; 9(8): e18754. Published online 2023 Aug 1. doi: 10.1016/j.heliyon.2023.e18754

PMCID:: PMC10440475

Abstract Article PDF–8.9M

Select item 1039887516.

High extracellular glucose promotes cell motility by modulating cell deformability and contractility via the cAMP-RhoA-ROCK axis in human breast cancer cells

Mijung Oh, Skylar Batty, Nayan Banerjee, Tae-Hyung Kim

Mol Biol Cell. 2023 Jul 1; 34(8): ar79. Published online 2023 Jul 1. doi: 10.1091/mbc.E22-12-0560

PMCID:: PMC10398875

Abstract Article PDF–7.7M

Select item 1033785417.

LncRNA ZNNT1 induces p53 degradation by interfering with the interaction between p53 and the SART3-USP15 complex

Kenzui Taniue, Takeaki Oda, Tomoatsu Hayashi, Yuki Kamoshida, Yasuko Takeda, Anzu Sugawara, Yuki Shimoura, Lumi Negishi, Takeshi Nagashima, Mariko Okada-Hatakeyama, Yoshifumi Kawamura, Naoki Goshima, Nobuyoshi Akimitsu, Tetsu Akiyama

PNAS Nexus. 2023 Jul; 2(7): pgad220. Published online 2023 Jul 4. doi: 10.1093/pnasnexus/pgad220

PMCID:: PMC10337854

Abstract Article PDF–851K

Select item 1031494818.

SUMOylation of Rho-associated protein kinase 2 induces goblet cell metaplasia in allergic airways

Dan Tan, Meiping Lu, Yuqing Cai, Weibo Qi, Fugen Wu, Hangyang Bao, Meiyu Qv, Qiangqiang He, Yana Xu, Xiangzhi Wang, Tingyu Shen, Jiahao Luo, Yangxun He, Junsong Wu, Lanfang Tang, Muhammad Qasim Barkat, Chengyun Xu, Ximei Wu

Nat Commun. 2023; 14: 3887. Published online 2023 Jul 1. doi: 10.1038/s41467-023-39600-4

PMCID:: PMC10314948

Abstract Article PDF–3.8M

Select item 1029012419.

Structure of human TRPV4 in complex with GTPase RhoA

Kirill D. Nadezhdin, Irina A. Talyzina, Aravind Parthasarathy, Arthur Neuberger, David X. Zhang, Alexander I. Sobolevsky

Nat Commun. 2023; 14: 3733. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39346-z

PMCID:: PMC10290124

Abstract Article PDF–4.4M

Select item 1029008120.

TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease

Do Hoon Kwon, Feng Zhang, Brett A. McCray, Shasha Feng, Meha Kumar, Jeremy M. Sullivan, Wonpil Im, Charlotte J. Sumner, Seok-Yong Lee

Nat Commun. 2023; 14: 3732. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39345-0

PMCID:: PMC10290081

Abstract Article PDF–6.1M

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