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Select item 105119201.

Another Breach in the Wall: Impaired Epithelial DUOX2 Activity Fuels Metabolic Syndrome

Marianna Parlato, Nadine Cerf-Bensussan

Cell Mol Gastroenterol Hepatol. 2023; 16(4): 648–649. Published online 2023 Jul 28. doi: 10.1016/j.jcmgh.2023.07.005

PMCID:: PMC10511920

Article PDF–215K

Select item 101076412.

DUOX2 regulates secreted factors in virus‐infected respiratory epithelial cells that contribute to neutrophil attraction and activation

Dacquin M. Kasumba, Sandrine Huot, Elise Caron, Audray Fortin, Cynthia Laflamme, Natalia Zamorano Cuervo, Felix Lamontagne, Marc Pouliot, Nathalie Grandvaux

FASEB J. 2023 Feb; 37(2): e22765. Published online 2023 Jan 6. doi: 10.1096/fj.202201205R

PMCID:: PMC10107641

Abstract Article PDF–5.0M

Select item 93715113.

Increased NOX1 and DUOX2 expression in the colonic mucosa of patients with chronic functional constipation

Xiuqin Wei, Mei Xue, Chunbo Kang, Lei Gao, Mengqiao Zhang, Chao Ma, Wei Jia, Yufeng Zheng, Lei Cao, Pan Chen, Shujing Jiang, Fong-Fong Chu, Qiang Gao

Medicine (Baltimore) 2022 Aug 12; 101(32): e30028. Published online 2022 Aug 12. doi: 10.1097/MD.0000000000030028

PMCID:: PMC9371511

Abstract Article PDF–1.2M

Select item 80872034.

DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk

Helmut Grasberger, Andrew T. Magis, Elisa Sheng, Matthew P. Conomos, Min Zhang, Lea S. Garzotto, Guoqing Hou, Shrinivas Bishu, Hiroko Nagao-Kitamoto, Mohamad El-Zaatari, Sho Kitamoto, Nobuhiko Kamada, Ryan W. Stidham, Yasutada Akiba, Jonathan Kaunitz, Yael Haberman, Subra Kugathasan, Lee A. Denson, Gilbert S. Omenn, John Y. Kao

J Clin Invest. 2021 May 3; 131(9): e141676. Published online 2021 May 3. doi: 10.1172/JCI141676

PMCID:: PMC8087203

Abstract Article PDF–4.6M

Select item 79432735.

DUOX2 As a Potential Prognostic Marker which Promotes Cell Motility and Proliferation in Pancreatic Cancer

Meng Cao, Peng-Bo Zhang, Peng-Fei Wu, Qun Chen, Wan-Li Ge, Guo-Dong Shi, Jie Yin, Bao-Bao Cai, Shou-Ji Cao, Yi Miao, Kui-Rong Jiang

Biomed Res Int. 2021; 2021: 6530298. Published online 2021 Mar 2. doi: 10.1155/2021/6530298

PMCID:: PMC7943273

Abstract Article PDF–2.9M

Select item 78775616.

DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3

Xue Zhang, Jing Han, Li Feng, Lianghui Zhi, Da Jiang, Bin Yu, Zhenya Zhang, Bo Gao, Cong Zhang, Meng Li, Lianmei Zhao, Guiying Wang

Carcinogenesis. 2021 Jan; 42(1): 105–117. Published online 2020 Jun 12. doi: 10.1093/carcin/bgaa056

PMCID:: PMC7877561

Abstract Article PDF–1.4M

Select item 78771867.

A truncated protein product of the germline variant of the DUOX2 gene leads to adenomatous polyposis

Mengyuan Yang, Yingxin Zhao, Yuwei Ding, Juan Wang, Yinuo Tan, Dong Xu, Ying Yuan

Cancer Biol Med. 2021 Feb 15; 18(1): 215–226. Published online 2021 Feb 15. doi: 10.20892/j.issn.2095-3941.2020.0305

Correction in:: Cancer Biol Med. 2022 Feb 15; 19(2): 263.

PMCID:: PMC7877186

Abstract Article PDF–1.2M

Select item 78178088.

Clinical and Genetic Features of a Large Monocentric Series of Familial Non-Medullary Thyroid Cancers

Valentina Cirello, Carla Colombo, Olga Karapanou, Gabriele Pogliaghi, Luca Persani, Laura Fugazzola

Front Endocrinol (Lausanne) 2020; 11: 589340. Published online 2021 Jan 7. doi: 10.3389/fendo.2020.589340

PMCID:: PMC7817808

Abstract Article PDF–386K

Select item 74729249.

Non-thermal dielectric-barrier discharge plasma induces reactive oxygen species by epigenetically modifying the expression of NADPH oxidase family genes in keratinocytes

Kyoung Ah Kang, Mei Jing Piao, Sangheum Eom, Sung-Young Yoon, Seungmin Ryu, Seong Bong Kim, Joo Mi Yi, Jin Won Hyun

Redox Biol. 2020 Oct; 37: 101698. Published online 2020 Aug 25. doi: 10.1016/j.redox.2020.101698

PMCID:: PMC7472924

Abstract Article PDF–7.6M

Select item 737208110.

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

Duc T. Tran, Anita Pottekat, Saiful A. Mir, Salvatore Loguercio, Insook Jang, Alexandre Rosa Campos, Kathleen M. Scully, Reyhaneh Lahmy, Ming Liu, Peter Arvan, William E. Balch, Randal J. Kaufman, Pamela Itkin-Ansari

Diabetes. 2020 Aug; 69(8): 1723–1734. Published online 2020 May 26. doi: 10.2337/db20-0245

PMCID:: PMC7372081

Abstract Article PDF–2.0M

Select item 721242911.

DUOX2 and DUOXA2 Variants Confer Susceptibility to Thyroid Dysgenesis and Gland-in-situ With Congenital Hypothyroidism

Fengqi Wang, Yucui Zang, Miaomiao Li, Wenmiao Liu, Yangang Wang, Xiaolong Yu, Hua Li, Fang Wang, Shiguo Liu

Front Endocrinol (Lausanne) 2020; 11: 237. Published online 2020 Apr 21. doi: 10.3389/fendo.2020.00237

PMCID:: PMC7212429

Abstract Article PDF–440K

Select item 684248512.

Dual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response

Sang Yeon Cho, Sungha Kim, Mi-Ju Son, Gwanghun Kim, Parul Singh, Ha Neul Kim, Hei-Gwon Choi, Heon Jong Yoo, Young Bok Ko, Byung Seok Lee, Hyuk Soo Eun

BMC Cancer. 2019; 19: 1078. Published online 2019 Nov 9. doi: 10.1186/s12885-019-6202-3

PMCID:: PMC6842485

Abstract Article PDF–4.1M

Select item 677813713.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 658811214.

DUOX2/DUOXA2 Mutations Frequently Cause Congenital Hypothyroidism that Evades Detection on Newborn Screening in the United Kingdom

Catherine Peters, Adeline K. Nicholas, Erik Schoenmakers, Greta Lyons, Shirley Langham, Eva G. Serra, Neil J. Sebire, Marina Muzza, Laura Fugazzola, Nadia Schoenmakers

Thyroid. 2019 Jun 1; 29(6): 790–801. Published online 2019 Jun 3. doi: 10.1089/thy.2018.0587

PMCID:: PMC6588112

Abstract Article PDF–6.0M

Select item 658119715.

Gain of additional BIRC3 protein functions through 3′UTR-mediated protein complex formation

Shih-Han Lee, Christine Mayr

Mol Cell. Author manuscript; available in PMC 2020 May 16.

Published in final edited form as: Mol Cell. 2019 May 16; 74(4): 701–712.e9. Published online 2019 Apr 1. doi: 10.1016/j.molcel.2019.03.006

PMCID:: PMC6581197

Abstract Article PDF–2.0M

Select item 638976516.

Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families

Yui Watanabe, Ryan J. Bruellman, Reham S. Ebrhim, Mohamed A. Abdullah, Alexandra M. Dumitrescu, Samuel Refetoff, Roy E. Weiss

Thyroid. 2019 Feb 1; 29(2): 302–304. Published online 2019 Feb 11. doi: 10.1089/thy.2018.0295

PMCID:: PMC6389765

Abstract Article PDF–176K

Select item 600690617.

DUOX2-mediated production of reactive oxygen species induces epithelial mesenchymal transition in 5-fluorouracil resistant human colon cancer cells

Kyoung Ah Kang, Yea Seong Ryu, Mei Jing Piao, Kristina Shilnikova, Hee Kyoung Kang, Joo Mi Yi, Mathias Boulanger, Rosa Paolillo, Guillaume Bossis, Sung Young Yoon, Seong Bong Kim, Jin Won Hyun

Redox Biol. 2018 Jul; 17: 224–235. Published online 2018 Apr 23. doi: 10.1016/j.redox.2018.04.020

PMCID:: PMC6006906

Abstract Article PDF–1.7M

Select item 576194818.

Myocardium of patients with dilated cardiomyopathy presents altered expression of genes involved in thyroid hormone biosynthesis

Carolina Gil-Cayuela, Ana Ortega, Estefanía Tarazón, Luis Martínez-Dolz, Juan Cinca, José Ramón González-Juanatey, Francisca Lago, Esther Roselló-Lletí, Miguel Rivera, Manuel Portolés

PLoS One. 2018; 13(1): e0190987. Published online 2018 Jan 10. doi: 10.1371/journal.pone.0190987

PMCID:: PMC5761948

Abstract Article PDF–1.9M

Select item 564325919.

Genetic Complexity of Crohn’s Disease in Two Large Ashkenazi Jewish Families

Adam P. Levine, Nikolas Pontikos, Elena R. Schiff, Luke Jostins, Doug Speed, NIDDK Inflammatory Bowel Disease Genetics Consortium, Laurence B. Lovat, Jeffrey C. Barrett, Helmut Grasberger, Vincent Plagnol, Anthony W. Segal

Gastroenterology. 2016 Oct; 151(4): 698–709. doi: 10.1053/j.gastro.2016.06.040