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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108178522.

Vascular injury activates the ELK1/SND1/SRF pathway to promote vascular smooth muscle cell proliferative phenotype and neointimal hyperplasia

Chao Su, Mingxia Liu, Xuyang Yao, Wei Hao, Jinzheng Ma, Yuanyuan Ren, Xingjie Gao, Lingbiao Xin, Lin Ge, Ying Yu, Minxin Wei, Jie Yang

Cell Mol Life Sci. 2024 Dec; 81(1): 59. Published online 2024 Jan 27. doi: 10.1007/s00018-023-05095-x

PMCID:: PMC10817852

Abstract Article PDF–3.7M

Select item 103897783.

ELK4 exerts opposite roles in cytokine/chemokine production and degranulation in activated mast cells

Yuji Huang, Zhehui Zhu, Weize Li, Yiqin Ge, Yanning Li, Juan Wang, Xia Peng, Lihui Lin, Jia Li, Chen-Ying Liu, Li Li

Front Immunol. 2023; 14: 1171380. Published online 2023 Jul 17. doi: 10.3389/fimmu.2023.1171380

PMCID:: PMC10389778

Abstract Article PDF–8.3M

Select item 93648304.

Loss of ELK1 has differential effects on age-dependent organ fibrosis

Jennifer T Cairns, Anthony Habgood, Rochelle C Edwards-Pritchard, Chitra Joseph, Alison E John, Chloe Wilkinson, Iain D Stewart, Jack Leslie, Burns C Blaxall, Katalin Sustak, Siegfried Alberti, Alfred Nordheim, Fiona Oakley, Gisli Jenkins, Amanda L Tatler

Int J Biochem Cell Biol. Author manuscript; available in PMC 2022 Aug 10.

Published in final edited form as: Int J Biochem Cell Biol. 2020 Mar; 120: 105668. Published online 2019 Dec 23. doi: 10.1016/j.biocel.2019.105668

PMCID:: PMC9364830

Abstract Article PDF–1.6M

Select item 90120845.

TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages

Louise Blair, Michael J. Pattison, Probir Chakravarty, Stamatia Papoutsopoulou, Latifa Bakiri, Erwin F. Wagner, Stephen Smale, Steven C. Ley

J Immunol. 2022 Feb 15; 208(4): 941–954. Published online 2022 Feb 15. doi: 10.4049/jimmunol.2100213

PMCID:: PMC9012084

Abstract Article PDF–1.7M

Select item 85813256.

MicroRNA‐150 and its target ETS‐domain transcription factor 1 contribute to inflammation in diabetic photoreceptors

Fei Yu, Michael L. Ko, Gladys Y.‐P. Ko

J Cell Mol Med. 2021 Nov; 25(22): 10724–10735. Published online 2021 Oct 26. doi: 10.1111/jcmm.17012

PMCID:: PMC8581325

Abstract Article PDF–1.3M

Select item 85414497.

Critical Protein–Protein Interactions Determine the Biological Activity of Elk-1, a Master Regulator of Stimulus-Induced Gene Transcription

Gerald Thiel, Tobias M. Backes, Lisbeth A. Guethlein, Oliver G. Rössler

Molecules. 2021 Oct; 26(20): 6125. Published online 2021 Oct 11. doi: 10.3390/molecules26206125

PMCID:: PMC8541449

Abstract Article PDF–3.2M

Select item 83821128.

The Elk1/MMP-9 axis regulates E-cadherin and occludin in ventilator-induced lung injury

Zhao Tao, Yan Jie, Zhang Mingru, Gu Changping, Yang Fan, Wu Haifeng, Wang Yuelan

Respir Res. 2021; 22: 233. Published online 2021 Aug 23. doi: 10.1186/s12931-021-01829-2

PMCID:: PMC8382112

Abstract Article PDF–13M

Select item 71564699.

The Ap-2α/Elk-1 axis regulates Sirpα-dependent tumor phagocytosis by tumor-associated macrophages in colorectal cancer

Xiaojiao Wang, Xi Luo, Chuan Chen, Ye Tang, Lian Li, Banghui Mo, Houjie Liang, Songtao Yu

Signal Transduct Target Ther. 2020; 5: 35. Published online 2020 Apr 15. doi: 10.1038/s41392-020-0124-z

PMCID:: PMC7156469

Abstract Article PDF–5.0M

Select item 693472610.

Critical role of CRAG, a splicing variant of centaurin-γ3/AGAP3, in ELK1-dependent SRF activation at PML bodies

Shun Nagashima, Keisuke Takeda, Isshin Shiiba, Mizuho Higashi, Toshifumi Fukuda, Takeshi Tokuyama, Nobuko Matsushita, Seiichi Nagano, Toshiyuki Araki, Mari Kaneko, Go Shioi, Ryoko Inatome, Shigeru Yanagi

Sci Rep. 2019; 9: 20107. Published online 2019 Dec 27. doi: 10.1038/s41598-019-56559-9

PMCID:: PMC6934726

Abstract Article PDF–1.4M

Select item 667001311.

Fibroblast growth factor signals regulate transforming growth factor‐β‐induced endothelial‐to‐myofibroblast transition of tumor endothelial cells via Elk1

Yuichi Akatsu, Naoya Takahashi, Yasuhiro Yoshimatsu, Shiori Kimuro, Tomoki Muramatsu, Akihiro Katsura, Nako Maishi, Hiroshi I. Suzuki, Johji Inazawa, Kyoko Hida, Kohei Miyazono, Tetsuro Watabe

Mol Oncol. 2019 Aug; 13(8): 1706–1724. Published online 2019 Jun 19. doi: 10.1002/1878-0261.12504

PMCID:: PMC6670013

Abstract Article PDF–1.2M

Select item 662367312.

Alterations of Molecular and Behavioral Responses to Cocaine by Selective Inhibition of Elk-1 Phosphorylation

Antoine Besnard, Nicolas Bouveyron, Vincent Kappes, Vincent Pascoli, Christiane Pagès, Nicolas Heck, Peter Vanhoutte, Jocelyne Caboche

J Neurosci. 2011 Oct 5; 31(40): 14296–14307. doi: 10.1523/JNEUROSCI.2890-11.2011

PMCID:: PMC6623673

Abstract Article PDF–3.0M

Select item 651429713.

Protein inhibitor of activated STAT1 Ser⁵⁰³ phosphorylation‐mediated Elk‐1 SUMOylation promotes neuronal survival in APP/PS1 mice

Shau‐Yu Liu, Yun‐Li Ma, Wei‐Lun Hsu, Hsin‐Ying Chiou, Eminy H.Y. Lee

Br J Pharmacol. 2019 Jun; 176(11): 1793–1810. Published online 2019 Apr 24. doi: 10.1111/bph.14656

PMCID:: PMC6514297

Abstract Article PDF–4.5M

Select item 638114314.

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

Ningning Li, Roya Babaei-Jadidi, Federica Lorenzi, Bradley Spencer-Dene, Philip Clarke, Enric Domingo, Eugene Tulchinsky, Robert G. J. Vries, David Kerr, Yihang Pan, Yulong He, David O. Bates, Ian Tomlinson, Hans Clevers, Abdolrahman S. Nateri

Oncogenesis. 2019 Mar; 8(3): 13. Published online 2019 Feb 19. doi: 10.1038/s41389-019-0125-3

PMCID:: PMC6381143

Abstract Article PDF–10M

Select item 620841315.

MicroRNA-139-3p regulates osteoblast differentiation and apoptosis by targeting ELK1 and interacting with long noncoding RNA ODSM

Yixuan Wang, Ke Wang, Zebing Hu, Hua Zhou, Lijun Zhang, Han Wang, Gaozhi Li, Shu Zhang, Xinsheng Cao, Fei Shi

Cell Death Dis. 2018 Nov; 9(11): 1107. Published online 2018 Oct 31. doi: 10.1038/s41419-018-1153-1

PMCID:: PMC6208413

Abstract Article PDF–3.4M

Select item 612121316.

ERK Signaling Controls Innate-like CD8⁺ T Cell Differentiation via the ELK4 (SAP-1) and ELK1 Transcription Factors

Diane Maurice, Patrick Costello, Mathew Sargent, Richard Treisman

J Immunol. 2018 Sep 15; 201(6): 1681–1691. Published online 2018 Aug 1. doi: 10.4049/jimmunol.1800704

PMCID:: PMC6121213

Abstract Article PDF–2.5M

Select item 574554817.

TNF-α Modulation of Intestinal Epithelial Tight Junction Barrier Is Regulated by ERK1/2 Activation of Elk-1

Rana Al-Sadi, Shuhong Guo, Dongmei Ye, Thomas Y. Ma

Am J Pathol. 2013 Dec; 183(6): 1871–1884. doi: 10.1016/j.ajpath.2013.09.001

PMCID:: PMC5745548

Abstract Article PDF–518K

Select item 556807418.

Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg

Yoichi Ohta, Takahiro Okabe, Colleen Larmour, Agnese Di Rocco, Marijke Maijenburg, Amanda Phillips, Nancy A. Speck, Shigeyuki Wakitani, Takashi Nakamura, Yoshihiko Yamada, Motomi Enomoto-Iwamoto, Maurizio Pacifici, Masahiro Iwamoto

Arthritis Rheumatol. Author manuscript; available in PMC 2017 Aug 23.

Published in final edited form as: Arthritis Rheumatol. 2015 Oct; 67(10): 2679–2690. doi: 10.1002/art.39243

PMCID:: PMC5568074

Abstract Article PDF–2.6M

Select item 487865619.

The ability of inner cell mass cells to self-renew as embryonic stem cells is acquired upon epiblast specification

Thorsten Boroviak, Remco Loos, Paul Bertone, Austin Smith, Jennifer Nichols

Nat Cell Biol. Author manuscript; available in PMC 2016 May 24.

Published in final edited form as: Nat Cell Biol. 2014 Jun; 16(6): 516–528. Published online 2014 May 25. doi: 10.1038/ncb2965

PMCID:: PMC4878656

Abstract Article PDF–7.9M

Select item 485029320.

Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression

Amanda L. Tatler, Anthony Habgood, Joanne Porte, Alison E. John, Anastasios Stavrou, Emily Hodge, Cheryl Kerama-Likoko, Shelia M. Violette, Paul H. Weinreb, Alan J. Knox, Geoffrey Laurent, Helen Parfrey, Paul John Wolters, William Wallace, Siegfried Alberti, Alfred Nordheim, Gisli Jenkins

J Biol Chem. 2016 Apr 29; 291(18): 9540–9553. Published online 2016 Feb 9. doi: 10.1074/jbc.M115.692368

PMCID:: PMC4850293

Abstract Article PDF–2.7M

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