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Select item 115144581.

Mechanism of BCDX2-mediated RAD51 nucleation on short ssDNA stretches and fork DNA

Masaki Akita, Paul Girvan, Mario Spirek, Jiri Novacek, David Rueda, Zbynek Prokop, Lumir Krejci

Nucleic Acids Res. 2024 Oct 28; 52(19): 11738–11752. Published online 2024 Sep 12. doi: 10.1093/nar/gkae770

PMCID:: PMC11514458

Abstract Article PDF–2.0M

Select item 113799432.

Hyper-recombination in ribosomal DNA is driven by long-range resection-independent RAD51 accumulation

Zita Gál, Stavroula Boukoura, Kezia Catharina Oxe, Sara Badawi, Blanca Nieto, Lea Milling Korsholm, Sille Blangstrup Geisler, Ekaterina Dulina, Anna Vestergaard Rasmussen, Christina Dahl, Wei Lv, Huixin Xu, Xiaoguang Pan, Stefanos Arampatzis, Danai-Eleni Stratou, Panagiotis Galanos, Lin Lin, Per Guldberg, Jiri Bartek, Yonglun Luo, Dorthe H. Larsen

Nat Commun. 2024; 15: 7797. Published online 2024 Sep 6. doi: 10.1038/s41467-024-52189-6

PMCID:: PMC11379943

Abstract Article PDF–8.2M

Select item 113637693.

Contribution of Radiation Sensitive Protein 51 Genotypes to Pterygium Risk in a Taiwanese Population

NING-YI HSIA, PEI-SHIN HU, CHIN-LIANG CHUANG, MEI-CHIN MONG, HUNG-CHIH CHEN, CHIA-WEN TSAI, YUN-CHI WANG, JAW-CHYUN CHEN, DA-TIAN BAU, WEN-SHIN CHANG

In Vivo. 2024 Sep-Oct; 38(5): 2197–2204. Published online 2024 Aug 26. doi: 10.21873/invivo.13683

PMCID:: PMC11363769

Abstract Article PDF–669K

Select item 113394044.

The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA

Sarah R. Hengel, Katherine G. Oppenheimer, Chelsea M. Smith, Matthew A. Schaich, Hayley L. Rein, Julieta Martino, Kristie E. Darrah, Maggie Witham, Oluchi C. Ezekwenna, Kyle R. Burton, Bennett Van Houten, Maria Spies, Kara A. Bernstein

Nat Commun. 2024; 15: 7197. Published online 2024 Aug 21. doi: 10.1038/s41467-024-51595-0

PMCID:: PMC11339404

Abstract Article PDF–3.5M

Select item 111627935.

Human AAA+ ATPase FIGNL1 suppresses RAD51-mediated ultra-fine bridge formation

Kenichiro Matsuzaki, Akira Shinohara, Miki Shinohara

Nucleic Acids Res. 2024 Jun 10; 52(10): 5774–5791. Published online 2024 Apr 10. doi: 10.1093/nar/gkae263

PMCID:: PMC11162793

Abstract Article PDF–1.7M

Select item 111598406.

Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non‐small‐cell lung cancer

Min Kim, Hyo‐Gyoung Kang, Shin Yup Lee, Hyung Cheol Lee, Eung Bae Lee, Yi Young Choi, Won Kee Lee, Sukki Cho, Guang Jin, Hyo‐Sung Jheon, Ji Woong Son, Myung‐Hoon Lee, Deuk Kju Jung, Seung Ick Cha, Chang Ho Kim, Young Mo Kang, Sin Kam, Tae Hoon Jung, Sanghoon Jheon, Jae Yong Park

Cancer Sci. 2010 Nov; 101(11): 2436–2442. Published online 2010 Jul 31. doi: 10.1111/j.1349-7006.2010.01699.x

PMCID:: PMC11159840

Abstract Article PDF–209K

Select item 110113767.

Human Rad51 Protein Requires Higher Concentrations of Calcium Ions for D-Loop Formation than for Oligonucleotide Strand Exchange

Axelle Renodon-Corniere, Tsutomu Mikawa, Naoyuki Kuwabara, Kentaro Ito, Dmitri Levitsky, Hiroshi Iwasaki, Masayuki Takahashi

Int J Mol Sci. 2024 Apr; 25(7): 3633. Published online 2024 Mar 24. doi: 10.3390/ijms25073633

PMCID:: PMC11011376

Abstract Article PDF–2.1M

Select item 109909318.

Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site

Takuro Shioi, Suguru Hatazawa, Eriko Oya, Noriko Hosoya, Wataru Kobayashi, Mitsuo Ogasawara, Takehiko Kobayashi, Yoshimasa Takizawa, Hitoshi Kurumizaka

Nature. 2024; 628(8006): 212–220. Published online 2024 Mar 20. doi: 10.1038/s41586-024-07196-4

PMCID:: PMC10990931

Abstract Article PDF–20M

Select item 109544809.

Trans-complementation by the RecB nuclease domain of RecBCD enzyme reveals new insight into RecA loading upon χ recognition

Theetha L Pavankumar, C Jason Wong, Yun Ka Wong, Maria Spies, Stephen C Kowalczykowski

Nucleic Acids Res. 2024 Mar 21; 52(5): 2578–2589. Published online 2024 Jan 23. doi: 10.1093/nar/gkae007

PMCID:: PMC10954480

Abstract Article PDF–1.4M

Select item 1094298410.

RAD51 restricts DNA over-replication from re-activated origins

Sergio Muñoz, Elena Blanco-Romero, Daniel González-Acosta, Sara Rodriguez-Acebes, Diego Megías, Massimo Lopes, Juan Méndez

EMBO J. 2024 Mar; 43(6): 1043–1064. Published online 2024 Feb 15. doi: 10.1038/s44318-024-00038-z

PMCID:: PMC10942984

Abstract Article PDF–5.7M

Select item 1092383111.

GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer

Zu Ye, Shengfeng Xu, Yin Shi, Xueqian Cheng, Yuan Zhang, Sunetra Roy, Sarita Namjoshi, Michael A. Longo, Todd M. Link, Katharina Schlacher, Guang Peng, Dihua Yu, Bin Wang, John A. Tainer, Zamal Ahmed

Nat Commun. 2024; 15: 2132. Published online 2024 Mar 8. doi: 10.1038/s41467-024-46283-y

PMCID:: PMC10923831

Abstract Article PDF–3.7M

Select item 1086507312.

Association between polymorphisms of the DNA repair genes RAD51 and OGG1 and risk of cardiovascular disease

Amar Alomair, Abdullah Alamri, Jilani Shaik, Salman Aljafari, Mohammed Ba Abdullah, Mohammad Alanazi

Mol Med Rep. 2024 Mar; 29(3): 53. Published online 2024 Feb 7. doi: 10.3892/mmr.2024.13177

PMCID:: PMC10865073

Abstract Article PDF–1.5M

Select item 1082514513.

FLIP(C1orf112)-FIGNL1 complex regulates RAD51 chromatin association to promote viability after replication stress

Jessica D. Tischler, Hiroshi Tsuchida, Rosevalentine Bosire, Tommy T. Oda, Ana Park, Richard O. Adeyemi

Nat Commun. 2024; 15: 866. Published online 2024 Jan 29. doi: 10.1038/s41467-024-45139-9

PMCID:: PMC10825145

Abstract Article PDF–3.0M

Select item 1073466714.

Differential impact of cytoplasmic vs. nuclear RAD51 expression on breast cancer progression and patient prognosis

Yen-Yun Wang, Kuang-Hung Cheng, Amos C. Hung, Steven Lo, Pang-Yu Chen, Yi-Chia Wu, Ming-Feng Hou, Shyng-Shiou F. Yuan

Int J Oncol. 2024 Feb; 64(2): 12. Published online 2023 Dec 7. doi: 10.3892/ijo.2023.5600

PMCID:: PMC10734667

Abstract Article PDF–6.6M

Select item 1073446315.

SARS-CoV-2 exploits cellular RAD51 to promote viral propagation: implication of RAD51 inhibitor as a potential drug candidate against COVID-19

Thuy X. Pham, Trang T. X. Huynh, Jiwon Choi, Jae-Bong Lee, Seok-Chan Park, Bumseok Kim, Yun-Sook Lim, Soon B. Hwang

J Virol. 2023 Dec; 97(12): e01737-23. Published online 2023 Dec 5. doi: 10.1128/jvi.01737-23

PMCID:: PMC10734463

Abstract Article PDF–7.7M

Select item 1071658116.

Fanconi anemia-associated mutation in RAD51 compromises the coordinated action of DNA-binding and ATPase activities

Sijia Liu, Akira Shinohara, Asako Furukohri

J Biol Chem. 2023 Dec; 299(12): 105424. Published online 2023 Nov 2. doi: 10.1016/j.jbc.2023.105424

PMCID:: PMC10716581

Abstract Article PDF–2.7M

Select item 1071343617.

Human RAD52 stimulates the RAD51-mediated homology search

Ali Akbar Muhammad, Clara Basto, Thibaut Peterlini, Josée Guirouilh-Barbat, Melissa Thomas, Xavier Veaute, Didier Busso, Bernard Lopez, Gerard Mazon, Eric Le Cam, Jean-Yves Masson, Pauline Dupaigne

Life Sci Alliance. 2024 Mar; 7(3): e202201751. Published online 2023 Dec 11. doi: 10.26508/lsa.202201751