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Select item 111590161.

Overexpression of leucine‐rich repeat‐containing G protein‐coupled receptor 5 in colorectal cancer

Hiroshi Uchida, Ken Yamazaki, Mariko Fukuma, Taketo Yamada, Tetsu Hayashida, Hirotoshi Hasegawa, Masaki Kitajima, Yuko Kitagawa, Michiie Sakamoto

Cancer Sci. 2010 Jul; 101(7): 1731–1737. Published online 2010 Mar 24. doi: 10.1111/j.1349-7006.2010.01571.x

Correction in:: Cancer Sci. 2010 Jul; 101(7): 1767.

PMCID:: PMC11159016

Abstract Article PDF–517K

Select item 103833102.

The Expression of Stem Cell Marker LGR5 and Its Coexpression with Β-Catenin in Sporadic Colorectal Carcinoma and Adenoma: A Comparative Immunohistochemical Study

Eman Mohamed Ahmed, Abeer Said Farag, Mohammed S. Abdelwahed, Mehenaz Hanbazazh, Abdulhadi Samman, Diaa Ashmawy, Nageh Rady Abd-Elhameed, Mohamed Tharwat, Alyaa E. Othman, Taiseer Ahmed Shawky, Radwa Mohamed Attia, Adel Abdelwahid Ibrahim, Sherif Azzam, Mohammed E. A. Elhussiny, Mohamed Nasr, Suhaib Alsayed Naeem, Wagih M. Abd-Elhay, Ahmed Mohammad Ali Alfaifi, Abdulkarim Hasan

Medicina (Kaunas) 2023 Jul; 59(7): 1233. Published online 2023 Jun 30. doi: 10.3390/medicina59071233

PMCID:: PMC10383310

Abstract Article PDF–3.3M

Select item 103197293.

LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands

Yukimatsu Toh, Ling Wu, Soohyun Park, Allison Wang, Jianghua Tu, Wangsheng Yu, Mingxin Zuo, Kendra S. Carmon, Qingyun J. Liu

Sci Rep. 2023; 13: 10796. Published online 2023 Jul 4. doi: 10.1038/s41598-023-37856-w

PMCID:: PMC10319729

Abstract Article PDF–3.3M

Select item 101626024.

Evaluation of LGR5 Cancer Stem Cell Marker Expression in Breast Cancer and Its Relationship with Hormonal Profile and Clinical Pathological Features

Fatemeh Montazer, Behnaz Boozari, Reza Alizadeh-Navaei

Asian Pac J Cancer Prev. 2023; 24(2): 467–470. doi: 10.31557/APJCP.2023.24.2.467

PMCID:: PMC10162602

Abstract Article PDF–800K

Select item 99562335.

TCF7L1 Regulates LGR5 Expression in Colorectal Cancer Cells

Carli M. King, Olivia M. Marx, Wei Ding, Walter A. Koltun, Gregory S. Yochum

Genes (Basel) 2023 Feb; 14(2): 481. Published online 2023 Feb 14. doi: 10.3390/genes14020481

PMCID:: PMC9956233

Abstract Article PDF–2.7M

Select item 96040116.

LGR5 promotes invasion and migration by regulating YAP activity in hypopharyngeal squamous cell carcinoma cells under inflammatory condition

Zijia Zhu, Shuyuan Yu, Kai Niu, Ping Wang

PLoS One. 2022; 17(10): e0275679. Published online 2022 Oct 26. doi: 10.1371/journal.pone.0275679

PMCID:: PMC9604011

Abstract Article PDF–3.2M

Select item 92795957.

LGR5 regulates osteogenic differentiation of human thoracic ligamentum flavum cells by Wnt signalling pathway

Xiaoxi Yang, Chuiguo Sun, Xiangyu Meng, Guanghui Chen, Tianqi Fan, Chi Zhang, Zhongqiang Chen

J Cell Mol Med. 2022 Jul; 26(14): 3862–3872. Published online 2022 Jun 6. doi: 10.1111/jcmm.17420

PMCID:: PMC9279595

Abstract Article PDF–14M

Select item 92498648.

Differential epithelial and stromal LGR5 expression in ovarian carcinogenesis

Hyesung Kim, Dong Hui Lee, Eunsun Park, Jae Kyung Myung, Jeong Hwan Park, Dong Il Kim, Se Ik Kim, Maria Lee, Younghoon Kim, Chul Min Park, Chang Lim Hyun, Young Hee Maeng, Cheol Lee, Bogun Jang

Sci Rep. 2022; 12: 11200. Published online 2022 Jul 1. doi: 10.1038/s41598-022-15234-2

PMCID:: PMC9249864

Abstract Article PDF–22M

Select item 88508949.

LGR5, HES1 and ATOH1 in Young Rectal Cancer Patients in Egyptian

Heba Morsy, Ahmed Gaballah, Mohamed Samir, Vandrome Nakundi, Mohamed Shamseya, Hanan Mahrous, Abeer Ghazal, Mervat Hashish, Waleed Arafat

Asian Pac J Cancer Prev. 2021 Sep; 22(9): 2819–2830. doi: 10.31557/APJCP.2021.22.9.2819

PMCID:: PMC8850894

Abstract Article PDF–596K

Select item 881822610.

LGR5 expression and clinicopathological features of the invasive front in the fat infiltration area of pancreatic cancer

Masato Kamakura, Takeshi Uehara, Mai Iwaya, Shiho Asaka, Shota Kobayashi, Tomoyuki Nakajima, Yasuhiro Kinugawa, Tadanobu Nagaya, Takahiro Yoshizawa, Akira Shimizu, Hiroyoshi Ota, Takeji Umemura

Diagn Pathol. 2022; 17: 21. Published online 2022 Feb 5. doi: 10.1186/s13000-022-01203-w

PMCID:: PMC8818226

Abstract Article PDF–952K

Select item 874509011.

Clinical Significance of Stem Cell Biomarkers EpCAM, LGR5 and LGR4 mRNA Levels in Lymph Nodes of Colon Cancer Patients

Manar AbdelMageed, Hager Tarek H. Ismail, Lina Olsson, Gudrun Lindmark, Marie-Louise Hammarström, Sten Hammarström, Basel Sitohy

Int J Mol Sci. 2022 Jan; 23(1): 403. Published online 2021 Dec 30. doi: 10.3390/ijms23010403

PMCID:: PMC8745090

Abstract Article PDF–2.7M

Select item 842372612.

Expression of LGR5 in mammary myoepithelial cells and in triple-negative breast cancers

Hyun Ju Lee, Jae Kyung Myung, Hye Sung Kim, Dong Hui Lee, Hyun Su Go, Jae Hyuck Choi, Hyun Min Koh, Su-Jae Lee, Bogun Jang

Sci Rep. 2021; 11: 17750. Published online 2021 Sep 7. doi: 10.1038/s41598-021-97351-y

PMCID:: PMC8423726

Abstract Article PDF–6.0M

Select item 834592313.

LGR5 in Barrett's Esophagus and its Utility in Predicting Patients at Increased Risk of Advanced Neoplasia

Azfar Neyaz, Robert D. Odze, Steffen Rickelt, Linda T. Nieman, Jacob R. Bledsoe, Krishnan K. Mahadevan, Kshitij Arora, William R. Jeck, Martin S. Taylor, Manish Gala, Deepa T. Patil, Omer H. Yilmaz, Miguel N. Rivera, David T. Ting, Vikram Deshpande

Clin Transl Gastroenterol. 2021 Jan; 12(1): e00272. Published online 2020 Dec 22. doi: 10.14309/ctg.0000000000000272

PMCID:: PMC8345923

Abstract Article PDF–833K

Select item 824325214.

DCLK1, a Putative Stem Cell Marker in Human Cholangiocarcinoma

Nevi Lorenzo, Di Matteo Sabina, Carpino Guido, Zizzari Ilaria Grazia, Safarikia Samira, Ambrosino Valeria, Costantini Daniele, Overi Diletta, Giancotti Antonella, Monti Marco, Bosco Daniela, De Peppo Valerio, Oddi Andrea, De Rose Agostino Maria, Melandro Fabio, Bragazzi Maria Consiglia, Faccioli Jessica, Massironi Sara, Grazi Gian Luca, Panici Pierluigi Benedetti, Berloco Paquale Bartomeo, Giuliante Felice, Cardinale Vincenzo, Invernizzi Pietro, Caretti Giuseppina, Gaudio Eugenio, Alvaro Domenico

Hepatology. 2021 Jan; 73(1): 144–159. Published online 2021 Feb 6. doi: 10.1002/hep.31571

Correction in:: Hepatology. 2022 Mar; 75(3): 773.

PMCID:: PMC8243252

Abstract Article PDF–1.7M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 804593216.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Abstract Article PDF–1.9M

Select item 802898517.

LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem‐Like Cells

Susumu Nakata, Benito Campos, Josephine Bageritz, Justo Lorenzo Bermejo, Natalia Becker, Felix Engel, Till Acker, Stefan Momma, Christel Herold‐Mende, Peter Lichter, Bernhard Radlwimmer, Violaine Goidts

Brain Pathol. 2013 Jan; 23(1): 60–72. Published online 2012 Aug 30. doi: 10.1111/j.1750-3639.2012.00618.x

PMCID:: PMC8028985

Abstract Article PDF–1.7M

Select item 797569018.

CD151 promotes Colorectal Cancer progression by a crosstalk involving CEACAM6, LGR5 and Wnt signaling via TGFβ1

Tao Yang, Huibing Wang, Meng Li, Linqi Yang, Yu Han, Chao Liu, Baowen Zhang, Mingfa Wu, Gang Wang, Zhenya Zhang, Wenqi Zhang, Jianming Huang, Huaxing Zhang, Ting Cao, Pingping Chen, Wei Zhang

Int J Biol Sci. 2021; 17(3): 848–860. Published online 2021 Feb 17. doi: 10.7150/ijbs.53657

Correction in:: Int J Biol Sci. 2023; 19(10): 3290–3291.

PMCID:: PMC7975690

Abstract Article PDF–2.4M

Select item 793640919.

LGR5 expression is associated with prognosis in poorly differentiated gastric adenocarcinoma

Takehito Ehara, Takeshi Uehara, Tomoyuki Nakajima, Yasuhiro Kinugawa, Shota Kobayashi, Mai Iwaya, Hiroyoshi Ota, Yuji Soejima

BMC Cancer. 2021; 21: 228. Published online 2021 Mar 6. doi: 10.1186/s12885-021-07913-6

PMCID:: PMC7936409

Abstract Article PDF–1.0M

Select item 790594420.

Unlike LGR4, LGR5 potentiates Wnt–β-catenin signaling without sequestering E3 ligases

Soohyun Park, Ling Wu, Jianghua Tu, Wangsheng Yu, Yukimatsu Toh, Kendra S. Carmon, Qingyun J. Liu

Sci Signal. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Sci Signal. 2020 Dec 1; 13(660): eaaz4051. Published online 2020 Dec 1. doi: 10.1126/scisignal.aaz4051

PMCID:: PMC7905944

Abstract Article PDF–2.3M

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