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Select item 95496511.

Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway

Zhaoyi Liang, Lu Liu, Ruixia Gao, Chengchuan Che, Ge Yang

Cell Mol Biol Lett. 2022; 27: 88. Published online 2022 Oct 9. doi: 10.1186/s11658-022-00393-x

PMCID:: PMC9549651

Abstract Article PDF–6.7M

Select item 92145442.

WNT/RYK signaling functions as an antiinflammatory modulator in the lung mesenchyme

Hyun-Taek Kim, Paolo Panza, Khrievono Kikhi, Yuko Nakamichi, Ann Atzberger, Stefan Guenther, Clemens Ruppert, Andreas Guenther, Didier Y. R. Stainier

Proc Natl Acad Sci U S A. 2022 Jun 14; 119(24): e2201707119. Published online 2022 Jun 7. doi: 10.1073/pnas.2201707119

PMCID:: PMC9214544

Abstract Article PDF–2.8M

Select item 92063153.

Comprehensive analysis reveals COPB2 and RYK associated with tumor stages of larynx squamous cell carcinoma

Guojin Zhou, Shoude Zhang, Mao Jin, Sunhong Hu

BMC Cancer. 2022; 22: 667. Published online 2022 Jun 17. doi: 10.1186/s12885-022-09766-z

PMCID:: PMC9206315

Abstract Article PDF–14M

Select item 91714114.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 85409855.

PAX7, PAX9 and RYK Expression in Cleft Affected Tissue

Mārtiņš Vaivads, Ilze Akota, Māra Pilmane

Medicina (Kaunas) 2021 Oct; 57(10): 1075. Published online 2021 Oct 8. doi: 10.3390/medicina57101075

PMCID:: PMC8540985

Abstract Article PDF–1.3M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 75439517.

Structural insights into pseudokinase domains of receptor tyrosine kinases

Joshua B. Sheetz, Sebastian Mathea, Hanna Karvonen, Ketan Malhotra, Deep Chatterjee, Wilhelmiina Niininen, Robert Perttilä, Franziska Preuss, Krishna Suresh, Steven E. Stayrook, Yuko Tsutsui, Ravi Radhakrishnan, Daniela Ungureanu, Stefan Knapp, Mark A. Lemmon

Mol Cell. Author manuscript; available in PMC 2021 Aug 6.

Published in final edited form as: Mol Cell. 2020 Aug 6; 79(3): 390–405.e7. Published online 2020 Jul 2. doi: 10.1016/j.molcel.2020.06.018

PMCID:: PMC7543951

Abstract Article PDF–3.0M

Select item 56634658.

A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome

Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar

Mol Cell. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004

PMCID:: PMC5663465

Abstract Article PDF–2.1M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 535511310.

RYK promotes the stemness of glioblastoma cells via the WNT/β-catenin pathway

Assunta Adamo, Danilo Fiore, Fabio De Martino, Giuseppina Roscigno, Alessandra Affinito, Elvira Donnarumma, Ilaria Puoti, Lucia Ricci Vitiani, Roberto Pallini, Cristina Quintavalle, Gerolama Condorelli

Oncotarget. 2017 Feb 21; 8(8): 13476–13487. Published online 2017 Jan 9. doi: 10.18632/oncotarget.14564

PMCID:: PMC5355113

Abstract Article PDF–5.7M

Select item 530822611.

Wnt5A/Ryk signaling critically affects barrier function in human vascular endothelial cells

Tom Skaria, Esther Bachli, Gabriele Schoedon

Cell Adh Migr. 2017; 11(1): 24–38. Published online 2016 May 9. doi: 10.1080/19336918.2016.1178449

PMCID:: PMC5308226

Abstract Article PDF–1.3M

Select item 461721112.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 460899713.

Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef

Nicholas J. Matheson, Jonathan Sumner, Kim Wals, Radu Rapiteanu, Michael P. Weekes, Raphael Vigan, Julia Weinelt, Michael Schindler, Robin Antrobus, Ana S.H. Costa, Christian Frezza, Clary B. Clish, Stuart J.D. Neil, Paul J. Lehner

Cell Host Microbe. 2015 Oct 14; 18(4): 409–423. doi: 10.1016/j.chom.2015.09.003

PMCID:: PMC4608997

Abstract Article PDF–3.8M

Select item 456599014.

Human epicardial cell-conditioned medium contains HGF/IgG complexes that phosphorylate RYK and protect against vascular injury

Krithika S. Rao, Alexander Aronshtam, Keara L. McElory-Yaggy, Benjamin Bakondi, Peter VanBuren, Burton E. Sobel, Jeffrey L. Spees

Cardiovasc Res. 2015 Jul 15; 107(2): 277–286. Published online 2015 May 29. doi: 10.1093/cvr/cvv168

PMCID:: PMC4565990

Abstract Article PDF–743K

Select item 406898015.

The Wnt Receptor Ryk Reduces Neuronal and Cell Survival Capacity by Repressing FOXO Activity During the Early Phases of Mutant Huntingtin Pathogenicity

Cendrine Tourette, Francesca Farina, Rafael P. Vazquez-Manrique, Anne-Marie Orfila, Jessica Voisin, Sonia Hernandez, Nicolas Offner, J. Alex Parker, Sophie Menet, Jinho Kim, Jungmok Lyu, Si Ho Choi, Kerry Cormier, Christina K. Edgerly, Olivia L. Bordiuk, Karen Smith, Anne Louise, Michael Halford, Steven Stacker, Jean-Philippe Vert, Robert J. Ferrante, Wange Lu, Christian Neri

PLoS Biol. 2014 Jun; 12(6): e1001895. Published online 2014 Jun 24. doi: 10.1371/journal.pbio.1001895

Correction in:: PLoS Biol. 2014 Jul; 12(7): e1001925.

PMCID:: PMC4068980

Abstract Article PDF–2.8M

Select item 350353116.

Testing reported associations of genetic risk factors for oral clefts in a large Irish study population

Tonia C. Carter, Anne M. Molloy, Faith Pangilinan, James F. Troendle, Peadar N. Kirke, Mary R. Conley, David J. A. Orr, Michael Earley, Eamon McKiernan, Ena C. Lynn, Anne Doyle, John M. Scott, Lawrence C. Brody, James L. Mills

Birth Defects Res A Clin Mol Teratol. Author manuscript; available in PMC 2012 Nov 21.

Published in final edited form as: Birth Defects Res A Clin Mol Teratol. 2010 Feb; 88(2): 84–93. doi: 10.1002/bdra.20639

PMCID:: PMC3503531

Abstract Article PDF–345K

Select item 343618817.

The Wnt Receptor Ryk Plays a Role in Mammalian Planar Cell Polarity Signaling

Maria L. Macheda, Willy W. Sun, Kumudhini Kugathasan, Benjamin M. Hogan, Neil I. Bower, Michael M. Halford, You Fang Zhang, Bonnie E. Jacques, Graham J. Lieschke, Alain Dabdoub, Steven A. Stacker

J Biol Chem. 2012 Aug 24; 287(35): 29312–29323. Published online 2012 Jul 6. doi: 10.1074/jbc.M112.362681

PMCID:: PMC3436188

Abstract Article PDF–3.1M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317112319.

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

Jason D. Berndt, Atsushi Aoyagi, Peitzu Yang, Jamie N. Anastas, Lan Tang, Randall T. Moon

J Cell Biol. 2011 Sep 5; 194(5): 737–750. doi: 10.1083/jcb.201107021

PMCID:: PMC3171123

Abstract Article PDF–3.3M

Select item 290133620.

Maternal Genes and Facial Clefts in Offspring: A Comprehensive Search for Genetic Associations in Two Population-Based Cleft Studies from Scandinavia

Astanand Jugessur, Min Shi, Håkon Kristian Gjessing, Rolv Terje Lie, Allen James Wilcox, Clarice Ring Weinberg, Kaare Christensen, Abee Lowman Boyles, Sandra Daack-Hirsch, Truc Trung Nguyen, Lene Christiansen, Andrew Carl Lidral, Jeffrey Clark Murray

PLoS One. 2010; 5(7): e11493. Published online 2010 Jul 9. doi: 10.1371/journal.pone.0011493

PMCID:: PMC2901336

Abstract Article PDF–778K

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