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Items: 1 to 20 of 39

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Bob1 maintains T follicular helper cells for long-term humoral immunity
Masahiro Yanagi, Ippei Ikegami, Ryuta Kamekura, Tatsuya Sato, Taiki Sato, Shiori Kamiya, Kosuke Murayama, Sumito Jitsukawa, Fumie Ito, Akira Yorozu, Miho Kihara, Takaya Abe, Hiromi Takaki, Koji Kawata, Katsunori Shigehara, Satsuki Miyajima, Hirotaka Nishikiori, Akinori Sato, Noritsugu Tohse, Ken-ichi Takano, Hirofumi Chiba, Shingo Ichimiya
Commun Biol. 2024; 7: 185. Published online 2024 Feb 15. doi: 10.1038/s42003-024-05827-0
PMCID:
PMC10869348
AbstractArticlePDF–3.8M
3.
T Cell Specific BOB.1/OBF.1 Expression Promotes Germinal Center Response and T Helper Cell Differentiation
Annika C. Betzler, Jasmin Ezić, Tsima Abou Kors, Thomas K. Hoffmann, Thomas Wirth, Cornelia Brunner
Front Immunol. 2022; 13: 889564. Published online 2022 May 4. doi: 10.3389/fimmu.2022.889564
PMCID:
PMC9114770
AbstractArticlePDF–9.6M
4.
Targeting transcriptional coregulator OCA-B/Pou2af1 blocks activated autoreactive T cells in the pancreas and type 1 diabetes
Heejoo Kim, Jelena Perovanovic, Arvind Shakya, Zuolian Shen, Cody N. German, Andrea Ibarra, Jillian L. Jafek, Nai-Pin Lin, Brian D. Evavold, Danny H.-C. Chou, Peter E. Jensen, Xiao He, Dean Tantin
J Exp Med. 2021 Mar 1; 218(3): e20200533. Published online 2020 Dec 9. doi: 10.1084/jem.20200533
PMCID:
PMC7731945
AbstractArticlePDF–5.2M
5.
MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition
Xiangdong Lu, Chi-Shuen Chu, Terry Fang, Violeta Rayon-Estrada, Fang Fang, Alina Patke, Ye Qian, Stephen H. Clarke, Ari M. Melnick, Yi Zhang, F. Nina Papavasiliou, Robert G. Roeder
Cell Rep. Author manuscript; available in PMC 2019 Aug 12.
Published in final edited form as: Cell Rep. 2019 Jul 9; 28(2): 472–485.e5. doi: 10.1016/j.celrep.2019.06.029
PMCID:
PMC6690613
AbstractArticlePDF–2.6M
6.
Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line
Van Trung Chu, Robin Graf, Tristan Wirtz, Timm Weber, Jeremy Favret, Xun Li, Kerstin Petsch, Ngoc Tung Tran, Michael H. Sieweke, Claudia Berek, Ralf Kühn, Klaus Rajewsky
Proc Natl Acad Sci U S A. 2016 Nov 1; 113(44): 12514–12519. Published online 2016 Oct 11. doi: 10.1073/pnas.1613884113
PMCID:
PMC5098665
AbstractArticlePDF–1.5M
7.
Bob1 limits cellular frequency of T‐follicular helper cells
Keiji Yamashita, Koji Kawata, Hiroshi Matsumiya, Ryuta Kamekura, Sumito Jitsukawa, Tomonori Nagaya, Noriko Ogasawara, Ken‐ichi Takano, Terufumi Kubo, Sachiko Kimura, Katsunori Shigehara, Tetsuo Himi, Shingo Ichimiya
Eur J Immunol. 2016 Jun; 46(6): 1361–1370. Published online 2016 May 3. doi: 10.1002/eji.201545499
Correction in:
Eur J Immunol. 2016 Aug; 46(8): 2054.
PMCID:
PMC5084739
AbstractArticlePDF–2.0M
8.
The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6
Dennis Stauss, Cornelia Brunner, Friederike Berberich‐Siebelt, Uta E Höpken, Martin Lipp, Gerd Müller
EMBO J. 2016 Apr 15; 35(8): 881–898. Published online 2016 Mar 8. doi: 10.15252/embj.201591459
PMCID:
PMC4972135
AbstractArticlePDF–3.0M
9.
Oct1 and OCA-B are selectively required for CD4 memory T cell function
Arvind Shakya, Alon Goren, Alex Shalek, Cody N. German, Jeremy Snook, Vijay K. Kuchroo, Nir Yosef, Raymond C. Chan, Aviv Regev, Matthew A. Williams, Dean Tantin
J Exp Med. 2015 Nov 16; 212(12): 2115–2131. doi: 10.1084/jem.20150363
PMCID:
PMC4647264
AbstractArticlePDF–3.1M
10.
Mice without MacroH2A Histone Variants
John R. Pehrson, Lakshmi N. Changolkar, Carl Costanzi, N. Adrian Leu
Mol Cell Biol. 2014 Dec; 34(24): 4523–4533. doi: 10.1128/MCB.00794-14
PMCID:
PMC4248737
AbstractArticlePDF–1.1M
11.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
12.
A C-Terminal Acidic Domain Regulates Degradation of the Transcriptional Coactivator Bob1
John M. Lindner, Christina S. F. Wong, Andreas Möller, Peter J. Nielsen
Mol Cell Biol. 2013 Dec; 33(23): 4628–4640. doi: 10.1128/MCB.01590-12
PMCID:
PMC3838006
AbstractArticlePDF–3.2M
13.
Dynamic regulatory network controlling Th17 cell differentiation
Nir Yosef, Alex K. Shalek, Jellert T. Gaublomme, Hulin Jin, Youjin Lee, Amit Awasthi, Chuan Wu, Katarzyna Karwacz, Sheng Xiao, Marsela Jorgolli, David Gennert, Rahul Satija, Arvind Shakya, Diana Y. Lu, John J. Trombetta, Meenu R. Pillai, Peter J. Ratcliffe, Mathew L. Coleman, Mark Bix, Dean Tantin, Hongkun Park, Vijay K. Kuchroo, Aviv Regev
Nature. Author manuscript; available in PMC 2013 Oct 25.
Published in final edited form as: Nature. 2013 Apr 25; 496(7446): 461–468. Published online 2013 Mar 6. doi: 10.1038/nature11981
PMCID:
PMC3637864
AbstractArticlePDF–1.5M
14.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
15.
B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1
Alex Karnowski, Stephane Chevrier, Gabrielle T. Belz, Adele Mount, Dianne Emslie, Kathy D’Costa, David M. Tarlinton, Axel Kallies, Lynn M. Corcoran
J Exp Med. 2012 Oct 22; 209(11): 2049–2064. doi: 10.1084/jem.20111504
PMCID:
PMC3478936
AbstractArticlePDF–2.8M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58
Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara
Dev Cell. Author manuscript; available in PMC 2011 Jun 7.
Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011
PMCID:
PMC3110151
AbstractArticlePDF–2.0M
18.
Enforced Expression of the Transcriptional Coactivator OBF1 Impairs B Cell Differentiation at the Earliest Stage of Development
Alain Bordon, Nabil Bosco, Camille Du Roure, Boris Bartholdy, Hubertus Kohler, Gabriele Matthias, Antonius G. Rolink, Patrick Matthias
PLoS One. 2008; 3(12): e4007. Published online 2008 Dec 23. doi: 10.1371/journal.pone.0004007
PMCID:
PMC2603323
AbstractArticlePDF–972K
19.
Silencing and Nuclear Repositioning of the λ5 Gene Locus at the Pre-B Cell Stage Requires Aiolos and OBF-1
Alexander Karnowski, Chun Cao, Gabriele Matthias, Sebastian Carotta, Lynn M. Corcoran, Inga-Lill Martensson, Jane A. Skok, Patrick Matthias
PLoS One. 2008; 3(10): e3568. Published online 2008 Oct 30. doi: 10.1371/journal.pone.0003568
PMCID:
PMC2571989
AbstractArticlePDF–1.3M
20.
B Cell Response Is Required for Granuloma Formation in the Early Infection of Schistosoma japonicum
Fang Ji, Zhanjie Liu, Jianping Cao, Na Li, Zhijian Liu, Jinxin Zuo, Yan Chen, Xinzhi Wang, Jian Sun
PLoS One. 2008; 3(3): e1724. Published online 2008 Mar 5. doi: 10.1371/journal.pone.0001724
PMCID:
PMC2248706
AbstractArticlePDF–597K

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