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Select item 112558421.

IL-17A produced by POMC neurons regulates diet-induced obesity

Rosa Gallo, Ana Teijeiro, Mariana Angulo-Aguado, Nabil Djouder

iScience. 2024 Jul 19; 27(7): 110259. Published online 2024 Jun 12. doi: 10.1016/j.isci.2024.110259

PMCID:: PMC11255842

Abstract Article PDF–4.2M

Select item 110374222.

Asymmetric action of STAT transcription factors drive transcriptional outputs and cytokine specificity

Kiyoshi Hirahara, Atsushi Onodera, Alejandro Villarino, Michael Bonelli, Giuseppe Sciumè, Arian Laurence, Hong-Wei Sun, Stephen R. Brooks, Golnaz Vahedi, Han-Yu Shih, Gustavo Gutierrez-Cruz, Shigeru Iwata, Ryo Suzuki, Yohei Mikami, Yoshitaka Okamoto, Toshinori Nakayama, Steven Holland, Christopher A. Hunter, Yuka Kanno, John J. O’Shea

Immunity. Author manuscript; available in PMC 2024 Apr 23.

Published in final edited form as: Immunity. 2015 May 19; 42(5): 877–889. doi: 10.1016/j.immuni.2015.04.014

PMCID:: PMC11037422

Abstract Article PDF–2.3M

Select item 109851143.

Prmt7 regulates the JAK/STAT/Socs3 signaling pathway in postmenopausal cardiomyopathy

Byeong-Yun Ahn, Yan Zhang, Shibo Wei, Yideul Jeong, Dong-Hyun Park, Sang-Jin Lee, Young-Eun Leem, Jong-Sun Kang

Exp Mol Med. 2024 Mar; 56(3): 711–720. Published online 2024 Mar 14. doi: 10.1038/s12276-024-01193-3

PMCID:: PMC10985114

Abstract Article PDF–4.3M

Select item 103186454.

SOCS3 inhibits the mesenchymal stromal cell secretory factor SDF-1-mediated improvement of islet function in non-obese diabetic mice

Mingxing Sui, Tuo Li, Hanlan Lu, Yanhua Li, Juan Huang, Pei Zhang, Shusen Wang, Li Zeng

Stem Cell Res Ther. 2023; 14: 172. Published online 2023 Jul 3. doi: 10.1186/s13287-023-03347-y

PMCID:: PMC10318645

Abstract Article PDF–5.2M

Select item 102398505.

Socs3 expression in myeloid cells modulates the pathogenesis of dextran sulfate sodium (DSS)-induced colitis

Lianna Zhou, Zhaoqi Yan, Wei Yang, Jessica A. Buckley, Sameer Al Diffalha, Etty N. Benveniste, Hongwei Qin

Front Immunol. 2023; 14: 1163987. Published online 2023 May 22. doi: 10.3389/fimmu.2023.1163987

PMCID:: PMC10239850

Abstract Article PDF–3.9M

Select item 101794276.

SOCS3 Protein Mediates the Therapeutic Efficacy of Mesenchymal Stem Cells against Acute Lung Injury

Young Eun Kim, Dong Kyung Sung, Yuna Bang, Se In Sung, Misun Yang, So Yoon Ahn, Yun Sil Chang

Int J Mol Sci. 2023 May; 24(9): 8256. Published online 2023 May 4. doi: 10.3390/ijms24098256

PMCID:: PMC10179427

Abstract Article PDF–2.3M

Select item 99136127.

SOCS1 Deficiency Promotes Hepatocellular Carcinoma via SOCS3-Dependent CDKN1A Induction and NRF2 Activation

Md Gulam Musawwir Khan, Nadia Boufaied, Mehdi Yeganeh, Rajani Kandhi, Stephanie Petkiewicz, Ankur Sharma, Akihiko Yoshimura, Gerardo Ferbeyre, David P. Labbé, Sheela Ramanathan, Subburaj Ilangumaran

Cancers (Basel) 2023 Feb; 15(3): 905. Published online 2023 Jan 31. doi: 10.3390/cancers15030905

PMCID:: PMC9913612

Abstract Article PDF–2.6M

Select item 98519778.

Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis

Xu Wang, Chao Yang, Xuejie Wang, Jinmin Miao, Weitao Chen, Yiren Zhou, Ying Xu, Yongyan An, Aifang Cheng, Wenkang Ye, Mengxian Chen, Dong Song, Xue Yuan, Jiguang Wang, Peiyuan Qian, Angela Ruohao Wu, Zhong-Yin Zhang, Kai Liu

Neuron. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: Neuron. 2023 Jan 18; 111(2): 236–255.e7. Published online 2022 Nov 11. doi: 10.1016/j.neuron.2022.10.028

PMCID:: PMC9851977

Abstract Article PDF–3.6M

Select item 96267399.

Targeting PTEN but not SOCS3 resists an age-dependent decline in promoting axon sprouting

Cédric G. Geoffroy, Jessica M. Meves, Hugo Jae Mun Kim, Daniel Romaus-Sanjurjo, Theresa C. Sutherland, Jeffrey J. Li, Juliet Suen, Joshua J. Sanchez, Binhai Zheng

iScience. 2022 Nov 18; 25(11): 105383. Published online 2022 Oct 17. doi: 10.1016/j.isci.2022.105383

PMCID:: PMC9626739

Abstract Article PDF–3.3M

Select item 939132110.

Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells

Anne Jacobi, Nicholas M Tran, Wenjun Yan, Inbal Benhar, Feng Tian, Rebecca Schaffer, Zhigang He, Joshua Sanes

Neuron. Author manuscript; available in PMC 2023 Aug 17.

Published in final edited form as: Neuron. 2022 Aug 17; 110(16): 2625–2645.e7. Published online 2022 Jun 28. doi: 10.1016/j.neuron.2022.06.002

PMCID:: PMC9391321

Abstract Article PDF–4.6M

Select item 922347211.

SOCS3 Ablation in Leptin Receptor-Expressing Cells Causes Autonomic and Cardiac Dysfunctions in Middle-Aged Mice despite Improving Energy and Glucose Metabolism

João A. B. Pedroso, Ivson B. da Silva, Thais T. Zampieri, Leonardo T. Totola, Thiago S. Moreira, Ana P. T. Taniguti, Gabriela P. Diniz, Maria Luiza M. Barreto-Chaves, Jose Donato, Jr.

Int J Mol Sci. 2022 Jun; 23(12): 6484. Published online 2022 Jun 10. doi: 10.3390/ijms23126484

PMCID:: PMC9223472

Abstract Article PDF–3.6M

Select item 921355212.

NANOG initiates epiblast fate through the coordination of pluripotency genes expression

Nicolas Allègre, Sabine Chauveau, Cynthia Dennis, Yoan Renaud, Dimitri Meistermann, Lorena Valverde Estrella, Pierre Pouchin, Michel Cohen-Tannoudji, Laurent David, Claire Chazaud

Nat Commun. 2022; 13: 3550. Published online 2022 Jun 21. doi: 10.1038/s41467-022-30858-8

PMCID:: PMC9213552

Abstract Article PDF–4.4M

Select item 891856613.

IL-17A Mediates Demyelination by Activating A1 Astrocytes via SOCS3 During Angiostrongylus cantonensis Infection

Zongpu Zhou, Tuo Lin, Zhen Liu, Qian Ding, Zhixuan Ma, Wanqi Li, Fukang Xie, Yue Lan, Ying Feng

Front Immunol. 2022; 13: 845011. Published online 2022 Feb 28. doi: 10.3389/fimmu.2022.845011

PMCID:: PMC8918566

Abstract Article PDF–34M

Select item 869259814.

Long noncoding RNA Meg3 sponges miR-708 to inhibit intestinal tumorigenesis via SOCS3-repressed cancer stem cells growth

Shuo Zhang, Wei-Wei Ji, Wei Wei, Li-Xing Zhan, Xuan Huang

Cell Death Dis. 2022 Jan; 13(1): 25. Published online 2021 Dec 21. doi: 10.1038/s41419-021-04470-5

PMCID:: PMC8692598

Abstract Article PDF–4.6M

Select item 854636715.

Myeloid lineage contributes to pathological choroidal neovascularization formation via SOCS3

Tianxi Wang, Pingzhu Zhou, Xuemei Xie, Yohei Tomita, Steve Cho, Demetrios Tsirukis, Enton Lam, Hongbo Robert Luo, Ye Sun

EBioMedicine. 2021 Nov; 73: 103632. Published online 2021 Oct 21. doi: 10.1016/j.ebiom.2021.103632

PMCID:: PMC8546367

Abstract Article PDF–6.6M

Select item 848526116.

Pro-protein convertase subtilisin/kexin type 9 promotes intestinal tumor development by activating Janus kinase 2/signal transducer and activator of transcription 3/SOCS3 signaling in Apc^Min/+ mice

Kai Yang, Jie Zhu, Huan-hua Luo, Shu-wen Yu, Lu Wang

Int J Immunopathol Pharmacol. 2021 Jan-Dec; 35: 20587384211038345. Published online 2021 Sep 29. doi: 10.1177/20587384211038345

PMCID:: PMC8485261

Abstract Article PDF–2.0M

Select item 847668117.

Altered microbiota by a high-fat diet accelerates lethal myeloid hematopoiesis associated with systemic SOCS3 deficiency

Kaori Cho, Takashi Ushiki, Hajime Ishiguro, Suguru Tamura, Masaya Araki, Tatsuya Suwabe, Takayuki Katagiri, Mari Watanabe, Yoko Fujimoto, Riuko Ohashi, Yoichi Ajioka, Ippei Shimizu, Shujiro Okuda, Masayoshi Masuko, Yoshimi Nakagawa, Hideyo Hirai, Warren S. Alexander, Hitoshi Shimano, Hirohito Sone

iScience. 2021 Oct 22; 24(10): 103117. Published online 2021 Sep 11. doi: 10.1016/j.isci.2021.103117

PMCID:: PMC8476681

Abstract Article PDF–7.2M

Select item 841005018.

Endothelial SOCS3 maintains homeostasis and promotes survival in endotoxemic mice

Nina Martino, Ramon Bossardi Ramos, Shuhan Lu, Kara Leyden, Lindsay Tomaszek, Sudeshna Sadhu, Gabrielle Fredman, Ariel Jaitovich, Peter A. Vincent, Alejandro P. Adam

JCI Insight. 2021 Jul 22; 6(14): e147280. Published online 2021 Jul 22. doi: 10.1172/jci.insight.147280

PMCID:: PMC8410050

Abstract Article PDF–17M

Select item 829776919.

SOCS3 deficiency in cardiomyocytes elevates sensitivity of ischemic preconditioning that synergistically ameliorates myocardial ischemia reperfusion injury

Shoichiro Nohara, Mai Yamamoto, Hideo Yasukawa, Takanobu Nagata, Jinya Takahashi, Koutatsu Shimozono, Toshiyuki Yanai, Tomoko Sasaki, Kota Okabe, Tatsuhiro Shibata, Daiki Akagaki, Kazutoshi Mawatari, Yoshihiro Fukumoto

PLoS One. 2021; 16(7): e0254712. Published online 2021 Jul 22. doi: 10.1371/journal.pone.0254712

PMCID:: PMC8297769

Abstract Article PDF–2.1M

Select item 816987220.

Interleukin-6 deficiency modulates testicular function by increasing the expression of suppressor of cytokine signaling 3 (SOCS3) in mice

Thaís Alves-Silva, Geanne Arantes Freitas, Talita Guerreiro Rodrigues Húngaro, Adriano Cleis Arruda, Lila Missae Oyama, Maria Christina Werneck Avellar, Ronaldo Carvalho Araujo

Sci Rep. 2021; 11: 11456. Published online 2021 Jun 1. doi: 10.1038/s41598-021-90872-6

PMCID:: PMC8169872

Abstract Article PDF–2.3M

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