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Select item 109238351.

CaSSiDI: novel single-cell “Cluster Similarity Scoring and Distinction Index” reveals critical functions for PirB and context-dependent Cebpb repression

Robert Nechanitzky, Parameswaran Ramachandran, Duygu Nechanitzky, Wanda Y. Li, Andrew C. Wakeham, Jillian Haight, Mary E. Saunders, Slava Epelman, Tak W. Mak

Cell Death Differ. 2024 Mar; 31(3): 265–279. Published online 2024 Feb 21. doi: 10.1038/s41418-024-01268-8

PMCID:: PMC10923835

Abstract Article PDF–7.4M

Select item 108939162.

C/EBPβ suppresses keratinocyte autonomous type 1 IFN response and p53 to increase cell survival and susceptibility to UVB-induced skin cancer

Hann W Tam, Jonathan R Hall, Zachary J Messenger, Dereje D Jima, John S House, Keith Linder, Robert C Smart

Carcinogenesis. 2019 Sep; 40(9): 1099–1109. Published online 2019 Feb 23. doi: 10.1093/carcin/bgz012

PMCID:: PMC10893916

Abstract Article PDF–3.5M

Select item 107126873.

Molecular mechanisms of snoRNA-IL15 crosstalk in adipocyte lipolysis and NK cell rejuvenation

Yaohua Zhang, Zilong Zhao, Lisa A. Huang, Yuan Liu, Yun Yao, Chengcao Sun, Yajuan Li, Zhao Zhang, Youqiong Ye, Fei Yuan, Tina K. Nguyen, Nikhil Reddy Garlapati, Andrew Wu, Sergey D. Egranov, Abigail S. Caudle, Aysegul A. Sahin, Bora Lim, Laura Beretta, George A. Calin, Dihua Yu, Mien-Chie Hung, Michael Curran, Katayoun Rezvani, Boyi Gan, Zhi Tan, Leng Han, Chunru Lin, Liuqing Yang

Cell Metab. Author manuscript; available in PMC 2024 Aug 8.

Published in final edited form as: Cell Metab. 2023 Aug 8; 35(8): 1457–1473.e13. Published online 2023 Jun 16. doi: 10.1016/j.cmet.2023.05.009

PMCID:: PMC10712687

Abstract Article PDF–4.7M

Select item 106904584.

Hematopoietic stem cells undergo a lymphoid to myeloid switch in early stages of emergency granulopoiesis

Karolina Vanickova, Mirko Milosevic, Irina Ribeiro Bas, Monika Burocziova, Asumi Yokota, Petr Danek, Srdjan Grusanovic, Mateusz Chiliński, Dariusz Plewczynski, Jakub Rohlena, Hideyo Hirai, Katerina Rohlenova, Meritxell Alberich‐Jorda

EMBO J. 2023 Dec; 42(23): e113527. Published online 2023 Oct 17. doi: 10.15252/embj.2023113527

PMCID:: PMC10690458

Abstract Article PDF–3.0M

Select item 105848685.

FSH and ApoE4 contribute to Alzheimer’s disease-like pathogenesis via C/EBPβ/δ-secretase in female mice

Jing Xiong, Seong Su Kang, Mengmeng Wang, Zhihao Wang, Yiyuan Xia, Jianming Liao, Xia Liu, Shan-Ping Yu, Zhaohui Zhang, Vitaly Ryu, Tony Yuen, Mone Zaidi, Keqiang Ye

Nat Commun. 2023; 14: 6577. Published online 2023 Oct 18. doi: 10.1038/s41467-023-42282-7

PMCID:: PMC10584868

Abstract Article PDF–7.1M

Select item 105775486.

Inhibition of abnormal C/EBPβ/α‐Syn signaling pathway through activation of Nrf2 ameliorates Parkinson's disease‐like pathology

Zefang Lin, Lixuan Huang, Qianqian Cao, Hanyue Luo, Wei Yao, Ji‐chun Zhang

Aging Cell. 2023 Oct; 22(10): e13958. Published online 2023 Aug 23. doi: 10.1111/acel.13958

PMCID:: PMC10577548

Abstract Article PDF–36M

Select item 105714197.

Activation of BZW1 by CEBPB in macrophages promotes eIF2α phosphorylation-mediated metabolic reprogramming and endoplasmic reticulum stress in MRL/lpr lupus-prone mice

Huimeng Qi, Zhaoguo Zheng, Qiang Liu

Cell Mol Biol Lett. 2023; 28: 79. Published online 2023 Oct 12. doi: 10.1186/s11658-023-00494-1

PMCID:: PMC10571419

Abstract Article PDF–6.7M

Select item 103582838.

Ablation of cDC2 development by triple mutations within the Zeb2 enhancer

Tian-Tian Liu, Sunkyung Kim, Pritesh Desai, Do-Hyun Kim, Xiao Huang, Stephen T. Ferris, Renee Wu, Feiya Ou, Takeshi Egawa, Steven J. Van Dyken, Michael S. Diamond, Peter F. Johnson, Masato Kubo, Theresa L. Murphy, Kenneth M. Murphy

Nature. Author manuscript; available in PMC 2023 Jul 20.

Published in final edited form as: Nature. 2022 Jul; 607(7917): 142–148. Published online 2022 Jun 22. doi: 10.1038/s41586-022-04866-z

PMCID:: PMC10358283

Abstract Article PDF–3.8M

Select item 101642759.

C/EBPβ deficiency enhances the keratinocyte innate immune response to direct activators of cytosolic pattern recognition receptors

John S. House, Sophia Gray, Jennifer R. Owen, Dereje D. Jima, Robert C. Smart, Jonathan R. Hall

Innate Immun. 2023 Jan; 29(1-2): 14–24. Published online 2023 Apr 24. doi: 10.1177/17534259231162192

PMCID:: PMC10164275

Abstract Article PDF–2.3M

Select item 1003257510.

High-fat diet-induced diabetes couples to Alzheimer’s disease through inflammation-activated C/EBPβ/AEP pathway

Pai Liu, Zhi-Hao Wang, Seong Su Kang, Xia Liu, Yiyuan Xia, Chi-Bun Chan, Keqiang Ye

Mol Psychiatry. Author manuscript; available in PMC 2023 Mar 22.

Published in final edited form as: Mol Psychiatry. 2022 Aug; 27(8): 3396–3409. Published online 2022 May 11. doi: 10.1038/s41380-022-01600-z

PMCID:: PMC10032575

Abstract Article PDF–1.7M

Select item 994030111.

FSH blockade improves cognition in mice with Alzheimer’s disease

Jing Xiong, Seong Su Kang, Zhihao Wang, Xia Liu, Tan-Chun Kuo, Funda Korkmaz, Ashley Padilla, Sari Miyashita, Pokman Chan, Zhaohui Zhang, Pavel Katsel, Jocoll Burgess, Anisa Gumerova, Kseniia Ievleva, Damini Sant, Shan-Ping Yu, Valeriia Muradova, Tal Frolinger, Daria Lizneva, Jameel Iqbal, Ki A. Goosens, Sakshi Gera, Clifford J. Rosen, Vahram Haroutunian, Vitaly Ryu, Tony Yuen, Mone Zaidi, Keqiang Ye

Nature. Author manuscript; available in PMC 2023 Feb 20.

Published in final edited form as: Nature. 2022 Mar; 603(7901): 470–476. Published online 2022 Mar 2. doi: 10.1038/s41586-022-04463-0

PMCID:: PMC9940301

Abstract Article PDF–6.0M

Select item 986517312.

C/EBPβ Regulates TFAM Expression, Mitochondrial Function and Autophagy in Cellular Models of Parkinson’s Disease

Ana Sierra-Magro, Fernando Bartolome, David Lozano-Muñoz, Jesús Alarcón-Gil, Elena Gine, Marina Sanz-SanCristobal, Sandra Alonso-Gil, Marta Cortes-Canteli, Eva Carro, Ana Pérez-Castillo, José A. Morales-García

Int J Mol Sci. 2023 Jan; 24(2): 1459. Published online 2023 Jan 11. doi: 10.3390/ijms24021459

PMCID:: PMC9865173

Abstract Article PDF–6.6M

Select item 982321913.

PPARγ and C/EBPα response to acute cold stress in brown adipose tissue

Kin H. Lau, Althea N. Waldhart, Holly Dykstra, Tracey Avequin, Ning Wu

iScience. 2023 Jan 20; 26(1): 105848. Published online 2022 Dec 21. doi: 10.1016/j.isci.2022.105848

PMCID:: PMC9823219

Abstract Article PDF–4.8M

Select item 979091814.

Inflammation-activated C/EBPβ mediates high-fat diet-induced depression-like behaviors in mice

Yiyi Li, Hongyu Chen, Jianhao Wang, Jiabei Wang, Xuan Niu, Chao Wang, Dongdong Qin, Fang Li, Yamei Wang, Jing Xiong, Songyan Liu, Liqin Huang, Xi Zhang, Feng Gao, Dandan Gao, Mingxia Fan, Xuan Xiao, Zhi-Hao Wang

Front Mol Neurosci. 2022; 15: 1068164. Published online 2022 Dec 12. doi: 10.3389/fnmol.2022.1068164

PMCID:: PMC9790918

Abstract Article PDF–7.1M

Select item 960943815.

Immune cell C/EBPβ deficiency is associated with hepatic mononuclear defects and spontaneous hepatitis but not steatohepatitis induced liver fibrosis

Itay Moshkovits, Ayelet Kaminitz, Debby Reuveni, Metsada Pasmanik‐Chor, Eli Brazowski, Alexander Mildner, Achim Leutz, Ehud Zigmond

Immun Inflamm Dis. 2022 Nov; 10(11): e728. Published online 2022 Oct 27. doi: 10.1002/iid3.728

PMCID:: PMC9609438

Abstract Article PDF–3.4M

Select item 951914916.

7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome

Hideaki Tomita, Kelly M Hines, Josi M Herron, Amy Li, David W Baggett, Libin Xu

eLife. 2022; 11: e67141. Published online 2022 Sep 16. doi: 10.7554/eLife.67141

PMCID:: PMC9519149

Abstract Article PDF–16M

Select item 950021917.

Exosomal miR-155 from gastric cancer induces cancer-associated cachexia by suppressing adipogenesis and promoting brown adipose differentiation via C/EPBβ

Ying Liu, Meng Wang, Ting Deng, Rui Liu, Tao Ning, Ming Bai, Guoguang Ying, Haiyang Zhang, Yi Ba

Cancer Biol Med. 2022 Sep 15; 19(9): 1301–1314. Published online 2022 Feb 19. doi: 10.20892/j.issn.2095-3941.2021.0220

PMCID:: PMC9500219

Abstract Article PDF–1.4M

Select item 938646418.

The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation

Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang

Mol Metab. 2022 Oct; 64: 101548. Published online 2022 Jul 19. doi: 10.1016/j.molmet.2022.101548

PMCID:: PMC9386464

Abstract Article PDF–6.6M

Select item 907126219.

Enhanced C/EBPβ function promotes hyperplastic versus hypertrophic fat tissue growth and prevents steatosis in response to high-fat diet feeding

Christine Müller, Laura M Zidek, Sabrina Eichwald, Gertrud Kortman, Mirjam H Koster, Cornelis F Calkhoven

eLife. 2022; 11: e62625. Published online 2022 Apr 22. doi: 10.7554/eLife.62625

PMCID:: PMC9071262

Abstract Article PDF–4.1M

Select item 896723120.

Neuronal C/EBPβ/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression

Yiyuan Xia, Hiroshi Qadota, Zhi-Hao Wang, Pai Liu, Xia Liu, Karen X. Ye, Courtney J. Matheny, Ken Berglund, Shan Ping Yu, Derek Drake, David A. Bennett, Xiao-Chuan Wang, Bruce A. Yankner, Guy M. Benian, Keqiang Ye

Sci Adv. 2022 Apr; 8(13): eabj8658. Published online 2022 Mar 30. doi: 10.1126/sciadv.abj8658

PMCID:: PMC8967231

Abstract Article PDF–9.9M

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