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Select item 108087381.

DEK deficiency suppresses mitophagy to protect against house dust mite-induced asthma

Qiaoyun Bai, Ruobai Liu, Changlin Quan, Xue Han, Dandan Wang, Chongyang Wang, Zhiguang Wang, Li Li, Liangchang Li, Hongmei Piao, Yilan Song, Guanghai Yan

Front Immunol. 2023; 14: 1289774. Published online 2024 Jan 11. doi: 10.3389/fimmu.2023.1289774

PMCID:: PMC10808738

Abstract Article PDF–23M

Select item 96038602.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 79924113.

Nuclear DEK preserves hematopoietic stem cells potential via NCoR1/HDAC3-Akt1/2-mTOR axis

Zhe Chen, Dawei Huo, Lei Li, Zhilong Liu, Zhigang Li, Shuangnian Xu, Yongxiu Huang, Weiru Wu, Chengfang Zhou, Yuanyuan Liu, Mei Kuang, Feng Wu, Hui Li, Pengxu Qian, Guanbin Song, Xudong Wu, Jieping Chen, Yu Hou

J Exp Med. 2021 May 3; 218(5): e20201974. Published online 2021 Mar 23. doi: 10.1084/jem.20201974

PMCID:: PMC7992411

Abstract Article PDF–7.5M

Select item 79689254.

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

Xiaochen Fan, V Pragathi Masamsetti, Jane QJ Sun, Kasper Engholm-Keller, Pierre Osteil, Joshua Studdert, Mark E Graham, Nicolas Fossat, Patrick PL Tam

eLife. 2021; 10: e62873. Published online 2021 Feb 8. doi: 10.7554/eLife.62873

PMCID:: PMC7968925

Abstract Article PDF–4.0M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74090926.

DEK Expression in Breast Cancer Cells Leads to the Alternative Activation of Tumor Associated Macrophages

Nicholas A. Pease, Miranda S. Shephard, Mathieu Sertorio, Susan E. Waltz, Lisa M. Privette Vinnedge

Cancers (Basel) 2020 Jul; 12(7): 1936. Published online 2020 Jul 17. doi: 10.3390/cancers12071936

PMCID:: PMC7409092

Abstract Article PDF–1.9M

Select item 65464797.

Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling

Maegan L. Capitano, Nirit Mor-Vaknin, Anjan K. Saha, Scott Cooper, Maureen Legendre, Haihong Guo, Rafael Contreras-Galindo, Ferdinand Kappes, Maureen A. Sartor, Christopher T. Lee, Xinxin Huang, David M. Markovitz, Hal E. Broxmeyer

J Clin Invest. 2019 Jun 3; 129(6): 2555–2570. Published online 2019 May 20. doi: 10.1172/JCI127460

PMCID:: PMC6546479

Abstract Article PDF–3.4M

Select item 63811438.

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

Ningning Li, Roya Babaei-Jadidi, Federica Lorenzi, Bradley Spencer-Dene, Philip Clarke, Enric Domingo, Eugene Tulchinsky, Robert G. J. Vries, David Kerr, Yihang Pan, Yulong He, David O. Bates, Ian Tomlinson, Hans Clevers, Abdolrahman S. Nateri

Oncogenesis. 2019 Mar; 8(3): 13. Published online 2019 Feb 19. doi: 10.1038/s41389-019-0125-3

PMCID:: PMC6381143

Abstract Article PDF–10M

Select item 62441839.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 606711110.

Neuroanatomical distribution of DEK protein in corticolimbic circuits associated with learning and memory in adult male and female mice

Valentina Ghisays, Elizabeth T. Nguyen, Joshua Streicher, Nicholas A. Pease, Maureen Fitzgerald, Christina M. Estrada, Ana Franco-Villanueva, Lisa Privette Vinnedge, Matia B. Solomon

Neuroscience. Author manuscript; available in PMC 2018 Jul 31.

Published in final edited form as: Neuroscience. 2018 Feb 10; 371: 254–267. Published online 2017 Nov 23. doi: 10.1016/j.neuroscience.2017.11.025

PMCID:: PMC6067111

Abstract Article PDF–3.4M

Select item 593680011.

Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis

Yves Mugabo, Mina Sadeghi, Nancy N. Fang, Thibault Mayor, Gareth E. Lim

J Biol Chem. 2018 May 4; 293(18): 6736–6750. Published online 2018 Mar 12. doi: 10.1074/jbc.M117.816272

PMCID:: PMC5936800

Abstract Article PDF–2.4M

Select item 588458012.

Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence

Marie C. Matrka, Katherine A. Cimperman, Sarah R. Haas, Geraldine Guasch, Lisa A. Ehrman, Ronald R. Waclaw, Kakajan Komurov, Adam Lane, Kathryn A. Wikenheiser-Brokamp, Susanne I. Wells

PLoS Genet. 2018 Mar; 14(3): e1007227. Published online 2018 Mar 14. doi: 10.1371/journal.pgen.1007227

PMCID:: PMC5884580

Abstract Article PDF–8.2M

Select item 584484613.

Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors

J. Serrano-Lopez, K. Nattamai, N.A. Pease, M.S. Shephard, A.M. Wellendorf, M. Sertorio, E.A. Smith, H. Geiger, S.I. Wells, J.A. Cancelas, L.M. Privette Vinnedge

Exp Hematol. Author manuscript; available in PMC 2019 Mar 1.

Published in final edited form as: Exp Hematol. 2018 Mar; 59: 40–50.e3. Published online 2017 Dec 27. doi: 10.1016/j.exphem.2017.12.009

PMCID:: PMC5844846

Abstract Article PDF–2.0M

Select item 535790514.

DEK is required for homologous recombination repair of DNA breaks

Eric A. Smith, Boris Gole, Nicholas A. Willis, Rebeca Soria, Linda M. Starnes, Eric F. Krumpelbeck, Anil G. Jegga, Abdullah M. Ali, Haihong Guo, Amom R. Meetei, Paul R. Andreassen, Ferdinand Kappes, Lisa M. Privette Vinnedge, Jeremy A. Daniel, Ralph Scully, Lisa Wiesmüller, Susanne I. Wells

Sci Rep. 2017; 7: 44662. Published online 2017 Mar 20. doi: 10.1038/srep44662

PMCID:: PMC5357905

Abstract Article PDF–2.0M

Select item 530382315.

DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis

Nirit Mor-Vaknin, Anjan Saha, Maureen Legendre, Carmelo Carmona-Rivera, M Asif Amin, Bradley J. Rabquer, Marta J. Gonzales-Hernandez, Julie Jorns, Smriti Mohan, Srilakshmi Yalavarthi, Dave A. Pai, Kristine Angevine, Shelley J. Almburg, Jason S. Knight, Barbara S. Adams, Alisa E. Koch, David A. Fox, David R. Engelke, Mariana J. Kaplan, David M. Markovitz

Nat Commun. 2017; 8: 14252. Published online 2017 Feb 6. doi: 10.1038/ncomms14252

PMCID:: PMC5303823

Abstract Article PDF–2.2M

Select item 458959816.

The DEK Oncoprotein Is a Critical Component of the EKLF/KLF1 Enhancer in Erythroid Cells

Felix Lohmann, Mohan Dangeti, Shefali Soni, Xiaoyong Chen, Antanas Planutis, Margaret H. Baron, Kyunghee Choi, James J. Bieker

Mol Cell Biol. 2015 Nov; 35(21): 3726–3738. Prepublished online 2015 Aug 24. Published online 2015 Sep 30. doi: 10.1128/MCB.00382-15

PMCID:: PMC4589598

Abstract Article PDF–2.9M

Select item 448608917.

Nuclear myosin 1 contributes to a chromatin landscape compatible with RNA polymerase II transcription activation

Bader Almuzzaini, Aishe A. Sarshad, Ann-Kristin Östlund Farrants, Piergiorgio Percipalle

BMC Biol. 2015; 13: 35. Published online 2015 Jun 5. doi: 10.1186/s12915-015-0147-z

PMCID:: PMC4486089

Abstract Article PDF–2.6M

Select item 427542518.

The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor positive breast cancers

Lisa M. Privette Vinnedge, Nancy M. Benight, Purnima K. Wagh, Nicholas A. Pease, Madison A. Nashu, Juana Serrano-Lopez, Allie K. Adams, Jose A. Cancelas, Susan E. Waltz, Susanne I. Wells

Oncogene. Author manuscript; available in PMC 2015 Oct 30.

Published in final edited form as: Oncogene. 2015 Apr 30; 34(18): 2325–2336. Published online 2014 Jun 23. doi: 10.1038/onc.2014.173

PMCID:: PMC4275425

Abstract Article PDF–1.7M

Select item 419937119.

The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity

Kristina Ivanauskiene, Erwan Delbarre, James D. McGhie, Thomas Küntziger, Lee H. Wong, Philippe Collas

Genome Res. 2014 Oct; 24(10): 1584–1594. doi: 10.1101/gr.173831.114

PMCID:: PMC4199371

Abstract Article PDF–1.3M

Select item 416043020.

DEK promotes HPV positive and negative head and neck cancer cell proliferation

Allie K. Adams, Grace E. Hallenbeck, Keith A. Casper, Yash J. Patil, Keith M. Wilson, Randall J. Kimple, Paul F. Lambert, David P. Witte, Weihong Xiao, Maura L. Gillison, Kathryn A. Wikenheiser-Brokamp, Trisha M. Wise-Draper, Susanne I. Wells

Oncogene. Author manuscript; available in PMC 2015 Aug 12.

Published in final edited form as: Oncogene. 2015 Feb 12; 34(7): 868–877. Published online 2014 Mar 10. doi: 10.1038/onc.2014.15

PMCID:: PMC4160430

Abstract Article PDF–1.0M

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