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Items: 1 to 20 of 28

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Loss of PARP7 Increases Type I Interferon Signaling in EO771 Breast Cancer Cells and Prevents Mammary Tumor Growth by Increasing Antitumor Immunity
Marit Rasmussen, Karoline Alvik, Vinicius Kannen, Ninni E. Olafsen, Linnea A. M. Erlingsson, Giulia Grimaldi, Akinori Takaoka, Denis M. Grant, Jason Matthews
Cancers (Basel) 2023 Jul; 15(14): 3689. Published online 2023 Jul 20. doi: 10.3390/cancers15143689
PMCID:
PMC10377955
AbstractArticlePDF–4.2M
3.
Reduced Colonic Mucosal Injury in 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Poly ADP-Ribose Polymerase (TIPARP/PARP7)-Deficient Mice
David Hutin, Karoline Alvik Hagen, Peng Shao, Kim Sugamori, Denis M. Grant, Jason Matthews
Int J Mol Sci. 2022 Jan; 23(2): 920. Published online 2022 Jan 15. doi: 10.3390/ijms23020920
PMCID:
PMC8779828
AbstractArticlePDF–2.7M
4.
2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)-Inducible Poly-ADP-Ribose Polymerase (TIPARP/PARP7) Catalytic Mutant Mice (TiparpH532A) Exhibit Increased Sensitivity to TCDD-Induced Hepatotoxicity and Lethality
David Hutin, Alexandra S Long, Kim Sugamori, Peng Shao, Sachin Kumar Singh, Marit Rasmussen, Ninni Elise Olafsen, Solveig Pettersen, Giulia Grimaldi, Denis M Grant, Jason Matthews
Toxicol Sci. 2021 Sep; 183(1): 154–169. Published online 2021 Jun 15. doi: 10.1093/toxsci/kfab075
PMCID:
PMC8404992
AbstractArticlePDF–1.6M
5.
Roles of the ubiquitin ligase CUL4B and ADP-ribosyltransferase TiPARP in TCDD-induced nuclear export and proteasomal degradation of the transcription factor AHR
Mercedes Paz Rijo, Silvia Diani-Moore, Chenyi Yang, Pengbo Zhou, Arleen B. Rifkind
J Biol Chem. 2021 Aug; 297(2): 100886. Published online 2021 Jun 16. doi: 10.1016/j.jbc.2021.100886
PMCID:
PMC8318916
AbstractArticlePDF–1.6M
6.
Post-Transcriptional Regulation of PARP7 Protein Stability Is Controlled by Androgen Signaling
Teddy Kamata, Chun-Song Yang, Tiffany A. Melhuish, Henry F. Frierson Jr., David Wotton, Bryce M. Paschal
Cells. 2021 Feb; 10(2): 363. Published online 2021 Feb 9. doi: 10.3390/cells10020363
PMCID:
PMC7916378
AbstractArticlePDF–26M
7.
Murine Coronavirus Infection Activates the Aryl Hydrocarbon Receptor in an Indoleamine 2,3-Dioxygenase-Independent Manner, Contributing to Cytokine Modulation and Proviral TCDD-Inducible-PARP Expression
Matthew E. Grunewald, Mohamed G. Shaban, Samantha R. Mackin, Anthony R. Fehr, Stanley Perlman
J Virol. 2020 Feb; 94(3): e01743-19. Prepublished online 2019 Nov 6. Published online 2020 Jan 17. doi: 10.1128/JVI.01743-19
PMCID:
PMC7000979
AbstractArticlePDF–5.8M
8.
Loss of Tiparp Results in Aberrant Layering of the Cerebral Cortex
Giulia Grimaldi, Barbora Vagaska, Oleksandr Ievglevskyi, Elena Kondratskaya, Joel C. Glover, Jason Matthews
eNeuro. 2019 Nov-Dec; 6(6): ENEURO.0239-19.2019. Prepublished online 2019 Nov 8. Published online 2019 Nov 22. doi: 10.1523/ENEURO.0239-19.2019
Correction in:
eNeuro. 2019 Nov-Dec; 6(6): ENEURO.0519-19.2019.
PMCID:
PMC6883171
AbstractArticlePDF–2.9M
9.
3-Methylcholanthrene Induces Chylous Ascites in TCDD-Inducible Poly-ADP-Ribose Polymerase (Tiparp) Knockout Mice
Tiffany E. Cho, Debbie Bott, Shaimaa Ahmed, David Hutin, Alvin Gomez, Laura Tamblyn, Angela C. Zhou, Tania H. Watts, Denis M. Grant, Jason Matthews
Int J Mol Sci. 2019 May; 20(9): 2312. Published online 2019 May 10. doi: 10.3390/ijms20092312
PMCID:
PMC6540065
AbstractArticlePDF–5.9M
10.
Hepatocyte-Specific Deletion of TIPARP, a Negative Regulator of the Aryl Hydrocarbon Receptor, Is Sufficient to Increase Sensitivity to Dioxin-Induced Wasting Syndrome
David Hutin, Laura Tamblyn, Alvin Gomez, Giulia Grimaldi, Helen Soedling, Tiffany Cho, Shaimaa Ahmed, Christin Lucas, Chakravarthi Kanduri, Denis M Grant, Jason Matthews
Toxicol Sci. 2018 Oct; 165(2): 347–360. Published online 2018 Jun 4. doi: 10.1093/toxsci/kfy136
PMCID:
PMC6154274
AbstractArticlePDF–1.3M
11.
Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke
Bing Han, Yuan Zhang, Yanhong Zhang, Ying Bai, Xufeng Chen, Rongrong Huang, Fangfang Wu, Shuo Leng, Jie Chao, John H. Zhang, Gang Hu, Honghong Yao
Autophagy. 2018; 14(7): 1164–1184. Published online 2018 Jul 20. doi: 10.1080/15548627.2018.1458173
PMCID:
PMC6103660
AbstractArticlePDF–3.3M
12.
Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response
Tatsuya Kozaki, Jun Komano, Daiki Kanbayashi, Michihiro Takahama, Takuma Misawa, Takashi Satoh, Osamu Takeuchi, Taro Kawai, Shigeomi Shimizu, Yoshiharu Matsuura, Shizuo Akira, Tatsuya Saitoh
Proc Natl Acad Sci U S A. 2017 Mar 7; 114(10): 2681–2686. Published online 2017 Feb 17. doi: 10.1073/pnas.1621508114
PMCID:
PMC5347618
AbstractArticlePDF–1.2M
13.
Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate
Aimin Li, Shudong Ma, Susan M. Smith, Matt K. Lee, Ashley Fischer, Zea Borok, Saverio Bellusci, Changgong Li, Parviz Minoo
BMC Biol. 2016; 14: 19. Published online 2016 Mar 16. doi: 10.1186/s12915-016-0242-9
PMCID:
PMC4793501
AbstractArticlePDF–2.1M
14.
Loss of the Mono-ADP-ribosyltransferase, Tiparp, Increases Sensitivity to Dioxin-induced Steatohepatitis and Lethality
Shaimaa Ahmed, Debbie Bott, Alvin Gomez, Laura Tamblyn, Adil Rasheed, Tiffany Cho, Laura MacPherson, Kim S. Sugamori, Yang Yang, Denis M. Grant, Carolyn L. Cummins, Jason Matthews
J Biol Chem. 2015 Jul 3; 290(27): 16824–16840. Published online 2015 May 13. doi: 10.1074/jbc.M115.660100
PMCID:
PMC4505429
AbstractArticlePDF–6.9M
15.
Aryl Hydrocarbon Receptor Repressor and TiPARP (ARTD14) Use Similar, but also Distinct Mechanisms to Repress Aryl Hydrocarbon Receptor Signaling
Laura MacPherson, Shaimaa Ahmed, Laura Tamblyn, Jean Krutmann, Irmgard Förster, Heike Weighardt, Jason Matthews
Int J Mol Sci. 2014 May; 15(5): 7939–7957. Published online 2014 May 6. doi: 10.3390/ijms15057939
PMCID:
PMC4057711
AbstractArticlePDF–1011K
16.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation
Laura MacPherson, Laura Tamblyn, Sharanya Rajendra, Fernando Bralha, J. Peter McPherson, Jason Matthews
Nucleic Acids Res. 2013 Feb; 41(3): 1604–1621. Published online 2012 Dec 25. doi: 10.1093/nar/gks1337
PMCID:
PMC3562000
AbstractArticlePDF–6.4M
19.
Target Gene Analysis by Microarrays and Chromatin Immunoprecipitation Identifies HEY Proteins as Highly Redundant bHLH Repressors
Julia Heisig, David Weber, Eva Englberger, Anja Winkler, Susanne Kneitz, Wing-Kin Sung, Elmar Wolf, Martin Eilers, Chia-Lin Wei, Manfred Gessler
PLoS Genet. 2012 May; 8(5): e1002728. Published online 2012 May 17. doi: 10.1371/journal.pgen.1002728
PMCID:
PMC3355086
AbstractArticlePDF–1.4M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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