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Select item 101811921.

Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control

Sabrina Schlienger, Patricia T. Yam, Nursen Balekoglu, Hugo Ducuing, Jean-Francois Michaud, Shirin Makihara, Daniel K. Kramer, Baoyu Chen, Alfonso Fasano, Alfredo Berardelli, Fadi F. Hamdan, Guy A. Rouleau, Myriam Srour, Frederic Charron

Sci Adv. 2023 May; 9(19): eadd5501. Published online 2023 May 12. doi: 10.1126/sciadv.add5501

PMCID:: PMC10181192

Abstract Article PDF–3.1M

Select item 100534032.

Git1-PGK1 interaction achieves self-protection against spinal cord ischemia-reperfusion injury by modulating Keap1/Nrf2 signaling

Tao Xu, Peng Gao, Yifan Huang, Mengyuan Wu, Jiang Yi, Zheng Zhou, Xuan Zhao, Tao Jiang, Hao Liu, Tao Qin, Zhenqi Yang, Xiaowei Wang, Tianyi Bao, Jian Chen, Shujie Zhao, Guoyong Yin

Redox Biol. 2023 Jun; 62: 102682. Published online 2023 Mar 20. doi: 10.1016/j.redox.2023.102682

PMCID:: PMC10053403

Abstract Article PDF–12M

Select item 96301683.

Brain-Specific Deletion of GIT1 Impairs Cognition and Alters Phosphorylation of Synaptic Protein Networks Implicated in Schizophrenia Susceptibility

Daniel M. Fass, Michael C. Lewis, Rushdy Ahmad, Matthew J. Szucs, Qiangge Zhang, Morgan Fleishman, Dongqing Wang, Myung Jong Kim, Jonathan Biag, Steven A. Carr, Edward M. Scolnick, Richard T. Premont, Stephen J. Haggarty

Mol Psychiatry. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Mol Psychiatry. 2022 Aug; 27(8): 3272–3285. Published online 2022 May 3. doi: 10.1038/s41380-022-01557-z

PMCID:: PMC9630168

Abstract Article PDF–1.8M

Select item 79936614.

GIT1 protects traumatically injured spinal cord by prompting microvascular endothelial cells to clear myelin debris

Bowen Wan, Cong Li, Ming Wang, Fanqi Kong, Qirui Ding, Chenliang Zhang, Hao Liu, Dingfei Qian, Wenlin Deng, Jian Chen, Pengyu Tang, Qian Wang, Shujie Zhao, Zheng Zhou, Tao Xu, Yifan Huang, Jun Gu, Jin Fan, Guoyong Yin

Aging (Albany NY) 2021 Mar 15; 13(5): 7067–7083. Published online 2021 Feb 17. doi: 10.18632/aging.202560

PMCID:: PMC7993661

Abstract Article PDF–1.7M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78020836.

Microcephaly with Altered Cortical Layering in GIT1 Deficiency Revealed by Quantitative Neuroimaging

Alexandra Badea, Robert Schmalzigaug, Woojoo Kim, Pamela Bonner, Umer Ahmed, G. Allan Johnson, Gary Cofer, Mark Foster, Robert J Anderson, Cristian Badea, Richard T. Premont

Magn Reson Imaging. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Magn Reson Imaging. 2021 Feb; 76: 26–38. Published online 2020 Sep 30. doi: 10.1016/j.mri.2020.09.023

PMCID:: PMC7802083

Abstract Article PDF–2.4M

Select item 76898027.

Macrophage GIT1 Contributes to Bone Regeneration by Regulating Inflammatory Responses in an ERK/NRF2‐Dependent Way

Shu‐Jie Zhao, Hao Liu, Jian Chen, Ding‐Fei Qian, Fan‐Qi Kong, Jian Jie, Guo‐Yong Yin, Qing‐Qing Li, Jin Fan

J Bone Miner Res. 2020 Oct; 35(10): 2015–2031. Published online 2020 Jul 9. doi: 10.1002/jbmr.4099

PMCID:: PMC7689802

Abstract Article PDF–12M

Select item 72950338.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

Select item 68694889.

GIT1 regulates angiogenic factor secretion in bone marrow mesenchymal stem cells via NF‐κB/Notch signalling to promote angiogenesis

Linwei Li, Pengyu Tang, Zheng Zhou, Qian Wang, Tao Xu, Shujie Zhao, Yifan Huang, Fanqi Kong, Wei Liu, Lin Cheng, Zhimin Zhou, Xuan Zhao, Changjiang Gu, Yongjun Luo, Gaojian Tao, Dingfei Qian, Jian Chen, Jin Fan, Guoyong Yin

Cell Prolif. 2019 Nov; 52(6): e12689. Published online 2019 Sep 10. doi: 10.1111/cpr.12689

PMCID:: PMC6869488

Abstract Article PDF–3.0M

Select item 672490710.

A GIT1/PIX/Rac/PAK Signaling Module Regulates Spine Morphogenesis and Synapse Formation through MLC

Huaye Zhang, Donna J. Webb, Hannelore Asmussen, Shuang Niu, Alan F. Horwitz

J Neurosci. 2005 Mar 30; 25(13): 3379–3388. doi: 10.1523/JNEUROSCI.3553-04.2005

PMCID:: PMC6724907

Abstract Article PDF–1.0M

Select item 671533711.

Loss of βPix Causes Defects in Early Embryonic Development, and Cell Spreading and Platelet-Derived Growth Factor-Induced Chemotaxis in Mouse Embryonic Fibroblasts

TaeIn Kang, Seung Joon Lee, Younghee Kwon, Dongeun Park

Mol Cells. 2019 Aug; 42(8): 589–596. Published online 2019 Aug 9. doi: 10.14348/molcells.2019.0140

PMCID:: PMC6715337

Abstract Article PDF–3.1M

Select item 669277012.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 668458313.

Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome

Abigail U. Carbonell, Chang Hoon Cho, Jaafar O. Tindi, Pamela A. Counts, Juliana C. Bates, Hediye Erdjument-Bromage, Svetlana Cvejic, Alana Iaboni, Ifat Kvint, Jenny Rosensaft, Ehud Banne, Evdokia Anagnostou, Thomas A. Neubert, Stephen W. Scherer, Sophie Molholm, Bryen A. Jordan

Nat Commun. 2019; 10: 3529. Published online 2019 Aug 6. doi: 10.1038/s41467-019-11437-w

PMCID:: PMC6684583

Abstract Article PDF–2.2M

Select item 629414414.

GIT1 contributes to autophagy in osteoclast through disruption of the binding of Beclin1 and Bcl2 under starvation condition

Shu-Jie Zhao, Fan-Qi Kong, Wei Cai, Tao Xu, Zhi-Min Zhou, Zi-Bin Wang, An-Di Xu, Ya-Qing Yang, Jian Chen, Peng-Yu Tang, Qian Wang, Lin Cheng, Yong-Jun Luo, Zheng Zhou, Lin-Wei Li, Yi-Fan Huang, Xuan Zhao, Guo-Yong Yin, Ming-Xin Xue, Jin Fan

Cell Death Dis. 2018 Dec; 9(12): 1195. Published online 2018 Dec 13. doi: 10.1038/s41419-018-1256-8

PMCID:: PMC6294144

Abstract Article PDF–2.3M

Select item 616939415.

Deletion of GIT1 Impacts eNOS Activity To Aggravate sFlt-1–Induced Preeclampsia Phenotype in Mice

Shenghong Zhang, Cuili Zou, Qiaoqin Zhang

G3 (Bethesda) 2018 Oct; 8(10): 3377–3382. Published online 2018 Aug 22. doi: 10.1534/g3.118.200509

PMCID:: PMC6169394

Abstract Article PDF–898K

Select item 586277116.

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury

Nat Genet. Author manuscript; available in PMC 2018 Aug 19.

Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7

PMCID:: PMC5862771

Abstract Article PDF–2.5M

Select item 585881417.

GIT1 regulates synaptic structural plasticity underlying learning

Amanda C. Martyn, Krisztian Toth, Robert Schmalzigaug, Nathan G. Hedrick, Ramona M. Rodriguiz, Ryohei Yasuda, William C. Wetsel, Richard T. Premont

PLoS One. 2018; 13(3): e0194350. Published online 2018 Mar 19. doi: 10.1371/journal.pone.0194350

PMCID:: PMC5858814

Abstract Article PDF–16M

Select item 564508218.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 558065619.

Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins

Meng Zhang, Dong Chen, Jing Xia, Wenqi Han, Xiekui Cui, Nils Neuenkirchen, Gretchen Hermes, Nenad Sestan, Haifan Lin

Genes Dev. 2017 Jul 1; 31(13): 1354–1369. doi: 10.1101/gad.298752.117

PMCID:: PMC5580656

Abstract Article PDF–695K

Select item 553412320.

GIT1 gene deletion delays chondrocyte differentiation and healing of tibial plateau fracture through suppressing proliferation and apoptosis of chondrocyte

Peng Chen, Wan-Li Gu, Ming-Zhi Gong, Jun Wang, Dong-Qing Li

BMC Musculoskelet Disord. 2017; 18: 320. Published online 2017 Jul 28. doi: 10.1186/s12891-017-1653-7

PMCID:: PMC5534123

Abstract Article PDF–1.4M

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