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Select item 114249781.

DDI2 protease controls embryonic development and inflammation via TCF11/NRF1

Monika Nedomova, Stefanie Haberecht-Müller, Sophie Möller, Simone Venz, Michaela Prochazkova, Jan Prochazka, Frantisek Sedlak, Kallayanee Chawengsaksophak, Elke Hammer, Petr Kasparek, Michael Adamek, Radislav Sedlacek, Jan Konvalinka, Elke Krüger, Klara Grantz Saskova

iScience. 2024 Oct 18; 27(10): 110893. Published online 2024 Sep 5. doi: 10.1016/j.isci.2024.110893

PMCID:: PMC11424978

Abstract Article PDF–6.1M

Select item 110888962.

Nuclear factor erythroid 2-related factor 2 promotes radioresistance by regulating glutamate-cysteine ligase modifier subunit and its unique immunoinvasive pattern

Zhaoyuan Xue, Yiliyaer Nuerrula, Yilidana Sitiwaerdi, Mayinur Eli

Biomol Biomed. 2024 Jun 1; 24(3): 545–559. Published online 2024 Jun 1. doi: 10.17305/bb.2024.10184

PMCID:: PMC11088896

Abstract Article PDF–9.2M

Select item 104042653.

Developmental changes in cerebral NAD and neuroenergetics of an antioxidant compromised mouse model of schizophrenia

Radek Skupienski, Pascal Steullet, Kim Q. Do, Lijing Xin

Transl Psychiatry. 2023; 13: 275. Published online 2023 Aug 5. doi: 10.1038/s41398-023-02568-2

PMCID:: PMC10404265

Abstract Article PDF–1.3M

Select item 102270084.

Prenatal exposure to benzo[a]pyrene depletes ovarian reserve and masculinizes embryonic ovarian germ cell transcriptome transgenerationally

Jinhwan Lim, Toshihiro Shioda, Kelli F. Malott, Keiko Shioda, Junko Odajima, Kathleen N. Leon Parada, Julie Nguyen, Samantha Getze, Melody Lee, Jonathon Nguyen, Samantha Reshel Blakeley, Vienna Trinh, Hong-An Truong, Ulrike Luderer

Sci Rep. 2023; 13: 8671. Published online 2023 May 29. doi: 10.1038/s41598-023-35494-w

PMCID:: PMC10227008

Abstract Article PDF–2.4M

Select item 99522055.

Fatal Epileptic Seizures in Mice Having Compromised Glutathione and Ascorbic Acid Biosynthesis

Ying Chen, Katherine D. Holland, Howard G. Shertzer, Daniel W. Nebert, Timothy P. Dalton

Antioxidants (Basel) 2023 Feb; 12(2): 448. Published online 2023 Feb 10. doi: 10.3390/antiox12020448

PMCID:: PMC9952205

Abstract Article PDF–4.2M

Select item 97340616.

Alterations in TRN-anterodorsal thalamocortical circuits affect sleep architecture and homeostatic processes in oxidative stress vulnerable Gclm^−/− mice

Christina Czekus, Pascal Steullet, Albert Orero López, Ivan Bozic, Thomas Rusterholz, Mojtaba Bandarabadi, Kim Q. Do, Carolina Gutierrez Herrera

Mol Psychiatry. 2022; 27(11): 4394–4406. Published online 2022 Jul 28. doi: 10.1038/s41380-022-01700-w

PMCID:: PMC9734061

Abstract Article PDF–4.3M

Select item 94819337.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 91989518.

Glutathione deficiency decreases lipid droplet stores and increases reactive oxygen species in mouse oocytes

Kelli F Malott, Samantha Reshel, Laura Ortiz, Ulrike Luderer

Biol Reprod. 2022 Jun; 106(6): 1218–1231. Published online 2022 Mar 3. doi: 10.1093/biolre/ioac032

PMCID:: PMC9198951

Abstract Article PDF–1.6M

Select item 90440089.

Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis

Oren Rom, Yuhao Liu, Alexandra C. Finney, Alia Ghrayeb, Ying Zhao, Yousef Shukha, Lu Wang, Krishani K. Rajanayake, Sandeep Das, Nabil A. Rashdan, Natan Weissman, Luisa Delgadillo, Bo Wen, Minerva T. Garcia-Barrio, Michael Aviram, Christopher G. Kevil, Arif Yurdagul, Jr., Christopher B. Pattillo, Jifeng Zhang, Duxin Sun, Tony Hayek, Eyal Gottlieb, Inbal Mor, Y Eugene Chen

Redox Biol. 2022 Jun; 52: 102313. Published online 2022 Apr 13. doi: 10.1016/j.redox.2022.102313

PMCID:: PMC9044008

Abstract Article PDF–12M

Select item 871511010.

Persistence of improved glucose homeostasis in Gclm null mice with age and cadmium treatment

Christopher M. Schaupp, Dianne Botta, Collin C. White, David K. Scoville, Sengkeo Srinouanprachanh, Theo K. Bammler, James MacDonald, Terrance J. Kavanagh

Redox Biol. 2022 Feb; 49: 102213. Published online 2021 Dec 20. doi: 10.1016/j.redox.2021.102213

PMCID:: PMC8715110

Abstract Article PDF–2.3M

Select item 830418511.

IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss

Adelaida M. Celaya, Lourdes Rodríguez-de la Rosa, Jose M. Bermúdez-Muñoz, José M. Zubeldia, Carlos Romá-Mateo, Carlos Avendaño, Federico V. Pallardó, Isabel Varela-Nieto

Cells. 2021 Jul; 10(7): 1686. Published online 2021 Jul 3. doi: 10.3390/cells10071686

PMCID:: PMC8304185

Abstract Article PDF–7.1M

Select item 820111712.

GSH-Independent Induction of ER Stress during Hypoglycaemia in the Retinal Cells of Mice

Daria Fresia, Enrica Cannizzaro, Angelica Borgo, Raphaël Roduit

J Clin Med. 2021 Jun; 10(11): 2529. Published online 2021 Jun 7. doi: 10.3390/jcm10112529

PMCID:: PMC8201117

Abstract Article PDF–2.7M

Select item 793877013.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 757785714.

MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia patients

Daniella Dwir, Basilio Giangreco, Lijing Xin, Liliane Tenenbaum, Jan-Harry Cabungcal, Pascal Steullet, Audrey Goupil, Martine Cleusix, Raoul Jenni, Abdelwahed Chtarto, Philipp S. Baumann, Paul Klauser, Philippe Conus, Rabindra Tirouvanziam, Michel Cuenod, Kim Q. Do

Mol Psychiatry. 2020; 25(11): 2889–2904. Published online 2019 Mar 25. doi: 10.1038/s41380-019-0393-5

Correction in:: Mol Psychiatry. 2020; 25(11): 3105.

PMCID:: PMC7577857

Abstract Article PDF–5.1M

Select item 741599115.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 718677916.

Antioxidant supplementation partially rescues accelerated ovarian follicle loss, but not oocyte quality, of glutathione-deficient mice

Jinhwan Lim, Samiha Ali, Lisa S Liao, Emily S Nguyen, Laura Ortiz, Samantha Reshel, Ulrike Luderer

Biol Reprod. 2020 Apr; 102(5): 1065–1079. Published online 2020 Jan 17. doi: 10.1093/biolre/ioaa009

PMCID:: PMC7186779

Abstract Article PDF–1.4M

Select item 663454517.

Redox Dysregulation Affects the Ventral But Not Dorsal Hippocampus: Impairment of Parvalbumin Neurons, Gamma Oscillations, and Related Behaviors

Pascal Steullet, Jan-Harry Cabungcal, Anita Kulak, Rudolf Kraftsik, Ying Chen, Timothy P. Dalton, Michel Cuenod, Kim Q. Do

J Neurosci. 2010 Feb 17; 30(7): 2547–2558. doi: 10.1523/JNEUROSCI.3857-09.2010

PMCID:: PMC6634545

Abstract Article PDF–3.4M

Select item 646478618.

Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss

Adelaida M Celaya, Isabel Sánchez-Pérez, Jose M Bermúdez-Muñoz, Lourdes Rodríguez-de la Rosa, Laura Pintado-Berninches, Rosario Perona, Silvia Murillo-Cuesta, Isabel Varela-Nieto

eLife. 2019; 8: e39159. Published online 2019 Apr 2. doi: 10.7554/eLife.39159

PMCID:: PMC6464786

Abstract Article PDF–5.9M

Select item 646392319.

Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia

Teresa Partearroyo, Silvia Murillo-Cuesta, Néstor Vallecillo, Jose M. Bermúdez-Muñoz, Lourdes Rodríguez-de la Rosa, Giacomo Mandruzzato, Adelaida M. Celaya, Steven H. Zeisel, María A. Pajares, Gregorio Varela-Moreiras, Isabel Varela-Nieto

FASEB J. 2019 May; 33(5): 5942–5956. Published online 2019 Feb 12. doi: 10.1096/fj.201801533R

PMCID:: PMC6463923

Abstract Article

Select item 623163820.

Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each

Afzal M. Dogar, Ramona Pauchard-Batschulat, Barbara Grisoni-Neupert, Larry Richman, Alexandra Paillusson, Sylvain Pradervand, Otto Hagenbüchle, Giovanna Ambrosini, Christoph D. Schmid, Philipp Bucher, Lukas C. Kühn

PLoS One. 2018; 13(11): e0206823. Published online 2018 Nov 12. doi: 10.1371/journal.pone.0206823

PMCID:: PMC6231638

Abstract Article PDF–3.8M

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