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Select item 113693641.

Role of the telomeric factor TRF2 in post-hypoxic brain damages

Shuaiyun Gao, Sheng Huang, Yiwen Xu, Bo Wang, Peng Cheng, Yiming Lu, Eric Gilson, Jing Ye

Redox Biol. 2024 Sep; 75: 103278. Published online 2024 Jul 25. doi: 10.1016/j.redox.2024.103278

PMCID:: PMC11369364

Abstract Article PDF–6.7M

Select item 105775732.

Intact mitochondrial function in the setting of telomere‐induced senescence

Daniel I. Sullivan, Fiona M. Bello, Agustin Gil Silva, Kevin M. Redding, Luca Giordano, Angela M. Hinchie, Kelly E. Loughridge, Ana L. Mora, Melanie Königshoff, Brett A. Kaufman, Michael J. Jurczak, Jonathan K. Alder

Aging Cell. 2023 Oct; 22(10): e13941. Published online 2023 Sep 8. doi: 10.1111/acel.13941

PMCID:: PMC10577573

Abstract Article PDF–4.8M

Select item 91610093.

TRF2-mediated telomere protection is dispensable in pluripotent stem cells

Marta Markiewicz-Potoczny, Anastasia Lobanova, Anisha M. Loeb, Oktay Kirak, Teresa Olbrich, Sergio Ruiz, Eros Lazzerini Denchi

Nature. Author manuscript; available in PMC 2022 Jun 2.

Published in final edited form as: Nature. 2021 Jan; 589(7840): 110–115. Published online 2020 Nov 25. doi: 10.1038/s41586-020-2959-4

PMCID:: PMC9161009

Abstract Article PDF–5.8M

Select item 89313624.

FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis

Nobuhiro Tanno, Kazumasa Takemoto, Yuki Takada-Horisawa, Ryuki Shimada, Sayoko Fujimura, Naoki Tani, Naoki Takeda, Kimi Araki, Kei-ichiro Ishiguro

iScience. 2022 Apr 15; 25(4): 104008. Published online 2022 Mar 1. doi: 10.1016/j.isci.2022.104008

PMCID:: PMC8931362

Abstract Article PDF–9.0M

Select item 88116505.

DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during aging

Sara Sepe, Francesca Rossiello, Valeria Cancila, Fabio Iannelli, Valentina Matti, Giada Cicio, Matteo Cabrini, Eugenia Marinelli, Busola R Alabi, Alessia di Lillo, Arianna Di Napoli, Jerry W Shay, Claudio Tripodo, Fabrizio d’Adda di Fagagna

EMBO Rep. 2022 Feb 3; 23(2): e53658. Published online 2021 Dec 2. doi: 10.15252/embr.202153658

PMCID:: PMC8811650

Abstract Article PDF–2.8M

Select item 86827696.

TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA

Parminder Kaur, Ryan Barnes, Hai Pan, Ariana C Detwiler, Ming Liu, Chelsea Mahn, Jonathan Hall, Zach Messenger, Changjiang You, Jacob Piehler, Robert C Smart, Robert Riehn, Patricia L Opresko, Hong Wang

Nucleic Acids Res. 2021 Dec 16; 49(22): 13000–13018. Published online 2021 Dec 9. doi: 10.1093/nar/gkab1142

PMCID:: PMC8682769

Abstract Article PDF–6.2M

Select item 85848527.

Molecular Consequences of Depression Treatment: A Potential In Vitro Mechanism for Antidepressants-Induced Reprotoxic Side Effects

Przemysław Sołek, Jennifer Mytych, Anna Tabęcka-Łonczyńska, Marek Koziorowski

Int J Mol Sci. 2021 Nov; 22(21): 11855. Published online 2021 Nov 1. doi: 10.3390/ijms222111855

PMCID:: PMC8584852

Abstract Article PDF–21M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 76143529.

TRF2-independent chromosome end protection during pluripotency

Phil Ruis, David Van Ly, Valerie Borel, Georgia R. Kafer, Afshan McCarthy, Steven Howell, Robert Blassberg, Ambrosius P. Snijders, James Briscoe, Kathy K. Niakan, Paulina Marzec, Anthony J. Cesare, Simon J. Boulton

Nature. Author manuscript; available in PMC 2023 Mar 23.

Published in final edited form as: Nature. 2021 Jan 7; 589(7840): 103–109. Published online 2020 Nov 25. doi: 10.1038/s41586-020-2960-y

PMCID:: PMC7614352

Abstract Article PDF–8.2M

Select item 721629610.

Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress

R. Garrett Morgan, Ashley E. Walker, Daniel W. Trott, Daniel R. Machin, Grant D. Henson, Kelly D. Reihl, Richard M. Cawthon, Eros L. Denchi, Yu Liu, Samuel I. Bloom, Tam T. Phuong, Russell S. Richardson, Lisa A. Lesniewski, Anthony J. Donato

J Mol Cell Cardiol. Author manuscript; available in PMC 2020 May 12.

Published in final edited form as: J Mol Cell Cardiol. 2019 Feb; 127: 74–82. Published online 2018 Nov 29. doi: 10.1016/j.yjmcc.2018.11.014

PMCID:: PMC7216296

Abstract Article PDF–1.5M

Select item 714568511.

FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis

Rong Hua, Huafang Wei, Chao Liu, Yue Zhang, Siyu Liu, Yueshuai Guo, Yiqiang Cui, Xin Zhang, Xuejiang Guo, Wei Li, Mingxi Liu

Nucleic Acids Res. 2019 Dec 16; 47(22): 11755–11770. Published online 2019 Nov 14. doi: 10.1093/nar/gkz992

PMCID:: PMC7145685

Abstract Article PDF–4.2M

Select item 705914112.

Mitochondrial function in skeletal myofibers is controlled by a TRF2‐SIRT3 axis over lifetime

Jérôme D. Robin, Maria‐Sol Jacome Burbano, Han Peng, Olivier Croce, Jean Luc Thomas, Camille Laberthonniere, Valerie Renault, Liudmyla Lototska, Mélanie Pousse, Florent Tessier, Serge Bauwens, Waiian Leong, Sabrina Sacconi, Laurent Schaeffer, Frédérique Magdinier, Jing Ye, Eric Gilson

Aging Cell. 2020 Mar; 19(3): e13097. Published online 2020 Jan 28. doi: 10.1111/acel.13097

PMCID:: PMC7059141

Abstract Article PDF–4.0M

Select item 667241113.

Telomere Protection Mechanisms Change during Neurogenesis and Neuronal Maturation: Newly Generated Neurons Are Hypersensitive to Telomere and DNA Damage

Aiwu Cheng, Kazuo Shin-ya, Ruiqian Wan, Sung-chun Tang, Takumi Miura, Hongyang Tang, Rina Khatri, Marc Gleichman, Xin Ouyang, Dong Liu, Hae-Rong Park, Jeffrey Y. Chiang, Mark P. Mattson

J Neurosci. 2007 Apr 4; 27(14): 3722–3733. doi: 10.1523/JNEUROSCI.0590-07.2007

PMCID:: PMC6672411

Abstract Article PDF–641K

Select item 578650414.

Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe

Pol Margalef, Panagiotis Kotsantis, Valerie Borel, Roberto Bellelli, Stephanie Panier, Simon J. Boulton

Cell. 2018 Jan 25; 172(3): 439–453.e14. doi: 10.1016/j.cell.2017.11.047

PMCID:: PMC5786504

Abstract Article PDF–5.7M

Select item 564128215.

Involvement of Atm and Trp53 in neural cell loss due to Terf2 inactivation during mouse brain development

Jusik Kim, Inseo Choi, Youngsoo Lee

Histochem Cell Biol. 2017; 148(5): 489–501. Published online 2017 Jun 15. doi: 10.1007/s00418-017-1591-3

PMCID:: PMC5641282

Abstract Article PDF–12M

Select item 547364416.

DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs

Francesca Rossiello, Julio Aguado, Sara Sepe, Fabio Iannelli, Quan Nguyen, Sethuramasundaram Pitchiaya, Piero Carninci, Fabrizio d’Adda di Fagagna

Nat Commun. 2017; 8: 13980. Published online 2017 Feb 27. doi: 10.1038/ncomms13980

Correction in:: Nat Commun. 2017; 8: 15344.

PMCID:: PMC5473644

Abstract Article PDF–2.5M

Select item 542512317.

The differential spatiotemporal expression pattern of shelterin genes throughout lifespan

Kay-Dietrich Wagner, Yilin Ying, Waiian Leong, Jie Jiang, Xuefei Hu, Yi Chen, Jean-François Michiels, Yiming Lu, Eric Gilson, Nicole Wagner, Jing Ye

Aging (Albany NY) 2017 Apr; 9(4): 1219–1228. Published online 2017 Apr 17. doi: 10.18632/aging.101223

PMCID:: PMC5425123

Abstract Article PDF–4.4M

Select item 541170518.

Different requirements of functional telomeres in neural stem cells and terminally differentiated neurons

Anastasia Lobanova, Robert She, Simon Pieraut, Charlie Clapp, Anton Maximov, Eros Lazzerini Denchi

Genes Dev. 2017 Apr 1; 31(7): 639–647. doi: 10.1101/gad.295402.116

PMCID:: PMC5411705

Abstract Article PDF–1.3M

Select item 528711219.

PHF11 promotes DSB resection, ATR signaling, and HR

Yi Gong, Naofumi Handa, Stephen C. Kowalczykowski, Titia de Lange

Genes Dev. 2017 Jan 1; 31(1): 46–58. doi: 10.1101/gad.291807.116

PMCID:: PMC5287112

Abstract Article PDF–664K

Select item 525560320.

Speedy A–Cdk2 binding mediates initial telomere–nuclear envelope attachment during meiotic prophase I independent of Cdk2 activation

Zhaowei Tu, Mustafa Bilal Bayazit, Hongbin Liu, Jingjing Zhang, Kiran Busayavalasa, Sanjiv Risal, Jingchen Shao, Ande Satyanarayana, Vincenzo Coppola, Lino Tessarollo, Meenakshi Singh, Chunwei Zheng, Chunsheng Han, Zijiang Chen, Philipp Kaldis, Jan-Åke Gustafsson, Kui Liu

Proc Natl Acad Sci U S A. 2017 Jan 17; 114(3): 592–597. Published online 2016 Dec 28. doi: 10.1073/pnas.1618465114

PMCID:: PMC5255603

Abstract Article PDF–1.4M

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