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Select item 111316871.

TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme

L. Verstrepen, T. Bekaert, T.-L. Chau, J. Tavernier, A. Chariot, R. Beyaert

Cell Mol Life Sci. 2008 Oct; 65(19): 2964–2978. Published online 2008 Jun 6. doi: 10.1007/s00018-008-8064-8

PMCID:: PMC11131687

Abstract Article PDF–2.1M

Select item 98282942.

miR-505-5p alleviates acute rejection of liver transplantation by inhibiting Myd88 and inducing M2 polarizationof Kupffer cells: miR-505-5p affects M2 polarization of Kupffer cells

Hao Chai, Zilun Lei, Yanyao Liu, Junhua Gong, Zhenrui Cao, Zuotian Huang, Hang Yang, Zhongjun Wu

Acta Biochim Biophys Sin (Shanghai) 2022 Aug; 54(8): 1148–1158. Published online 2022 Aug 8. doi: 10.3724/abbs.2022100

PMCID:: PMC9828294

Abstract Article PDF–8.2M

Select item 78687653.

Adamantane-linked isothiourea derivatives suppress the growth of experimental hepatocellular carcinoma via inhibition of TLR4-MyD88-NF-κB signaling

Hanan M Hassan, Lamya H Al-Wahaibi, George SG Shehatou, Ali A El-Emam

Am J Cancer Res. 2021; 11(2): 350–369. Published online 2021 Feb 1.

PMCID:: PMC7868765

Abstract Article PDF–5.0M

Select item 73124354.

Direct inhibition of the TLR4/MyD88 pathway by geniposide suppresses HIF‐1α‐independent VEGF expression and angiogenesis in hepatocellular carcinoma

Cheng Zhang, Ning Wang, Hor‐Yue Tan, Wei Guo, Feiyu Chen, Zhangfeng Zhong, Kwan Man, Sai Wah Tsao, Lixing Lao, Yibin Feng

Br J Pharmacol. 2020 Jul; 177(14): 3240–3257. Published online 2020 Apr 12. doi: 10.1111/bph.15046

PMCID:: PMC7312435

Abstract Article PDF–3.4M

Select item 72189645.

Association between interleukin-8 −251A/T polymorphism and the risk of tuberculosis: A meta-analysis

Qin Hu, Haibo Hua, Lihong Zhou, Xingwu Zou

J Int Med Res. 2020 May; 48(5): 0300060520917877. Published online 2020 May 11. doi: 10.1177/0300060520917877

PMCID:: PMC7218964

Abstract Article PDF–551K

Select item 70137186.

Fecal Microbiota Transplantation Prevents Intestinal Injury, Upregulation of Toll-Like Receptors, and 5-Fluorouracil/Oxaliplatin-Induced Toxicity in Colorectal Cancer

Ching-Wei Chang, Hung-Chang Lee, Li-Hui Li, Jen-Shiu Chiang Chiau, Tsang-En Wang, Wei-Hung Chuang, Ming-Jen Chen, Horng-Yuan Wang, Shou-Chuan Shih, Chia-Yuan Liu, Tung-Hu Tsai, Yu-Jen Chen

Int J Mol Sci. 2020 Jan; 21(2): 386. Published online 2020 Jan 8. doi: 10.3390/ijms21020386

PMCID:: PMC7013718

Abstract Article PDF–3.5M

Select item 69763767.

Promoter methylation status of ASC/TMS1/PYCARD is associated with decreased overall survival and TNM status in patients with early stage non-small cell lung cancer (NSCLC)

Maja Šutić, Antje Motzek, Gordana Bubanović, Matthias Linke, Ivan Sabol, Oliver Vugrek, Petar Ozretić, Luka Brčić, Sven Seiwerth, Željko Debeljak, Antonija Jakovčević, Zoran Janevski, Dinko Stančić-Rokotov, Andrea Vukić-Dugac, Marko Jakopović, Miroslav Samaržija, Ulrich Zechner, Jelena Knežević

Transl Lung Cancer Res. 2019 Dec; 8(6): 1000–1015. doi: 10.21037/tlcr.2019.12.08

PMCID:: PMC6976376

Abstract Article PDF–2.7M

Select item 69024258.

Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study

Brian J. Anderson, Carolyn S. Calfee, Kathleen D. Liu, John P. Reilly, Kirsten N. Kangelaris, Michael G. S. Shashaty, Aili L. Lazaar, Andrew I. Bayliffe, Robert J. Gallop, Todd A. Miano, Thomas G. Dunn, Erik Johansson, Jason Abbott, Alejandra Jauregui, Thomas Deiss, Kathryn Vessel, Annika Belzer, Hanjing Zhuo, Michael A. Matthay, Nuala J. Meyer, Jason D. Christie

Crit Care. 2019; 23: 400. Published online 2019 Dec 9. doi: 10.1186/s13054-019-2684-2

PMCID:: PMC6902425

Abstract Article PDF–1.0M

Select item 68899249.

MyD88 mediates colorectal cancer cell proliferation, migration and invasion via NF-κB/AP-1 signaling pathway

Guangwei Zhu, Zhibin Cheng, Yongjian Huang, Wei Zheng, Shugang Yang, Chunlin Lin, Jianxin Ye

Int J Mol Med. 2020 Jan; 45(1): 131–140. Published online 2019 Oct 31. doi: 10.3892/ijmm.2019.4390

PMCID:: PMC6889924

Abstract Article PDF–1.8M

Select item 677580010.

Curcumin inhibits cell proliferation and migration in NSCLC through a synergistic effect on the TLR4/MyD88 and EGFR pathways

Lanfeng Zhang, Xingyu Tao, Qiaofen Fu, Chunlei Ge, Ruilei Li, Zhen Li, Ye Zhu, Hui Tian, Qiaolin Li, Min Liu, Hongyan Hu, Baozhen Zeng, Zhuyin Lin, Chunyan Li, Rongcheng Luo, Xin Song

Oncol Rep. 2019 Nov; 42(5): 1843–1855. Published online 2019 Aug 14. doi: 10.3892/or.2019.7278

PMCID:: PMC6775800

Abstract Article PDF–1.7M

Select item 675517411.

Rapamycin improves sevoflurane-induced cognitive dysfunction in aged rats by mediating autophagy through the TLR4/MyD88/NF-κB signaling pathway

Yan Li, Lidan Liu, Yue Tian, Jin Zhang

Mol Med Rep. 2019 Oct; 20(4): 3085–3094. Published online 2019 Jul 31. doi: 10.3892/mmr.2019.10541

PMCID:: PMC6755174

Abstract Article PDF–1.1M

Select item 669197712.

Commensal Microbiota Promote Lung Cancer Development via γδ T Cells

Chengcheng Jin, Georgia Lagoudas, Chen Zhao, Susan Bullman, Arjun Bhutkar, Bo Hu, Samuel Ameh, Demi Sandel, Xu Sue Liang, Sarah Mazzilli, Mark T. Whary, Matthew Meyerson, Ronald Germain, Paul C. Blainey, James G. Fox, Tyler Jacks

Cell. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Cell. 2019 Feb 21; 176(5): 998–1013.e16. Published online 2019 Jan 31. doi: 10.1016/j.cell.2018.12.040

PMCID:: PMC6691977

Abstract Article PDF–2.3M

Select item 666493513.

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

Marciane Milanski, Giovanna Degasperi, Andressa Coope, Joseane Morari, Raphael Denis, Dennys E. Cintra, Daniela M. L. Tsukumo, Gabriel Anhe, Maria E. Amaral, Hilton K. Takahashi, Rui Curi, Helena C. Oliveira, José B. C. Carvalheira, Silvana Bordin, Mário J. Saad, Lício A. Velloso

J Neurosci. 2009 Jan 14; 29(2): 359–370. doi: 10.1523/JNEUROSCI.2760-08.2009

PMCID:: PMC6664935

Abstract Article PDF–820K

Select item 663924814.

The Toll-Like Receptor/MyD88/XBP1 Signaling Axis Mediates Skeletal Muscle Wasting during Cancer Cachexia

Kyle R. Bohnert, Praneeth Goli, Anirban Roy, Aditya K. Sharma, Guangyan Xiong, Yann S. Gallot, Ashok Kumar

Mol Cell Biol. 2019 Aug 1; 39(15): e00184-19. Prepublished online 2019 May 28. Published online 2019 Jul 16. doi: 10.1128/MCB.00184-19

PMCID:: PMC6639248

Abstract Article PDF–4.0M

Select item 649176715.

Baishouwu Extract Suppresses the Development of Hepatocellular Carcinoma via TLR4/MyD88/NF-κB Pathway

Yong-fang Ding, Zi-xuan Peng, Lan Ding, Yun-ru Peng

Front Pharmacol. 2019; 10: 389. Published online 2019 Apr 24. doi: 10.3389/fphar.2019.00389

PMCID:: PMC6491767

Abstract Article PDF–5.4M

Select item 643858616.

The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2

Astrid Skjesol, Mariia Yurchenko, Korbinian Bösl, Caroline Gravastrand, Kaja Elisabeth Nilsen, Lene Melsæther Grøvdal, Federica Agliano, Francesco Patane, Germana Lentini, Hera Kim, Giuseppe Teti, Aditya Kumar Sharma, Richard K. Kandasamy, Bjørnar Sporsheim, Kristian K. Starheim, Douglas T. Golenbock, Harald Stenmark, Mary McCaffrey, Terje Espevik, Harald Husebye

PLoS Pathog. 2019 Mar; 15(3): e1007684. Published online 2019 Mar 18. doi: 10.1371/journal.ppat.1007684

PMCID:: PMC6438586

Abstract Article PDF–4.8M

Select item 633422617.

Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis

Vasiliki Koliaraki, Niki Chalkidi, Ana Henriques, Christos Tzaferis, Apostolos Polykratis, Ari Waisman, Werner Muller, David J. Hackam, Manolis Pasparakis, George Kollias

Cell Rep. 2019 Jan 15; 26(3): 536–545.e4. Published online 2019 Jan 15. doi: 10.1016/j.celrep.2018.12.072