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Select item 109177801.

BHLHE40/41 regulate microglia and peripheral macrophage responses associated with Alzheimer’s disease and other disorders of lipid-rich tissues

Anna Podleśny-Drabiniok, Gloriia Novikova, Yiyuan Liu, Josefine Dunst, Rose Temizer, Chiara Giannarelli, Samuele Marro, Taras Kreslavsky, Edoardo Marcora, Alison Mary Goate

Nat Commun. 2024; 15: 2058. Published online 2024 Mar 6. doi: 10.1038/s41467-024-46315-7

PMCID:: PMC10917780

Abstract Article PDF–4.5M

Select item 103809482.

Approach to Functions of BHLHE41/DEC2 in Non-Small Lung Cancer Development

Tatsuhiko Furukawa, Kentaro Mimami, Toshiyuki Nagata, Masatasu Yamamoto, Masami Sato, Akihide Tanimoto

Int J Mol Sci. 2023 Jul; 24(14): 11731. Published online 2023 Jul 21. doi: 10.3390/ijms241411731

PMCID:: PMC10380948

Abstract Article PDF–598K

Select item 103644233.

Knockdown of DEC2 expression inhibits the proliferation of mesangial cells through suppressed glycolysis and p38 MAPK/Erk pathway in lupus nephritis

Huimeng Qi, Li Xu, Qiang Liu

Mol Med. 2023; 29: 99. Published online 2023 Jul 24. doi: 10.1186/s10020-023-00672-z

Correction in:: Mol Med. 2023; 29: 124.

PMCID:: PMC10364423

Abstract Article PDF–5.5M

Select item 100205594.

A differentiation roadmap of murine placentation at single-cell resolution

Xiangxiang Jiang, Yue Wang, Zhenyu Xiao, Long Yan, Shanshan Guo, Yiming Wang, Hao Wu, Xuehan Zhao, Xiaoyin Lu, Hongmei Wang

Cell Discov. 2023; 9: 30. Published online 2023 Mar 17. doi: 10.1038/s41421-022-00513-z

PMCID:: PMC10020559

Abstract Article PDF–5.8M

Select item 95204675.

Identification of novel B-1 transitional progenitors by B-1 lymphocyte fate-mapping transgenic mouse model Bhlhe41^dTomato-Cre

Hui Li, Yangyang Tang, Jinfeng Ren, Ruixue Bai, Lang Hu, Wenyu Jia, Yiwei Cao, Li Hong, Meizhen Xu, Sijia Gao, Yanbiao Shi, Shuai Pan, Liang Wang, Kuiyang Zheng, Shuli Zhao, Hui Wang

Front Immunol. 2022; 13: 946202. Published online 2022 Sep 15. doi: 10.3389/fimmu.2022.946202

PMCID:: PMC9520467

Abstract Article PDF–2.2M

Select item 88607646.

Dec2 inhibits macrophage pyroptosis to promote periodontal homeostasis

Dawei He, Xiaoyan Li, Fengzhu Zhang, Chen Wang, Yi Liu, Ujjal K. Bhawal, Jiang Sun

J Periodontal Implant Sci. 2022 Feb; 52(1): 28–38. Published online 2021 Aug 12. doi: 10.5051/jpis.2101380069

PMCID:: PMC8860764

Abstract Article PDF–3.3M

Select item 86896657.

Bhlhe40 function in activated B and T_FH cells restrains the GC reaction and prevents lymphomagenesis

René Rauschmeier, Annika Reinhardt, Charlotte Gustafsson, Vassilis Glaros, Artem V. Artemov, Josefine Dunst, Reshma Taneja, Igor Adameyko, Robert Månsson, Meinrad Busslinger, Taras Kreslavsky

J Exp Med. 2022 Feb 7; 219(2): e20211406. Published online 2021 Dec 17. doi: 10.1084/jem.20211406

PMCID:: PMC8689665

Abstract Article PDF–8.0M

Select item 84791358.

CHRONO and DEC1/DEC2 compensate for lack of CRY1/CRY2 in expression of coherent circadian rhythm but not in generation of circadian oscillation in the neonatal mouse SCN

Daisuke Ono, Ken-ichi Honma, Christoph Schmal, Toru Takumi, Takeshi Kawamoto, Katsumi Fujimoto, Yukio Kato, Sato Honma

Sci Rep. 2021; 11: 19240. Published online 2021 Sep 28. doi: 10.1038/s41598-021-98532-5

PMCID:: PMC8479135

Abstract Article PDF–2.2M

Select item 77909009.

Anti-aging effects of Korean Red Ginseng (KRG) in differentiated embryo chondrocyte (DEC) knockout mice

Youn Hee Nam, Seo Yule Jeong, Yun Hee Kim, Isabel Rodriguez, Wanlapa Nuankaew, Ujjal K. Bhawal, Bin Na Hong, Tong Ho Kang

J Ginseng Res. 2021 Jan; 45(1): 183–190. Published online 2020 Sep 16. doi: 10.1016/j.jgr.2020.09.003

PMCID:: PMC7790900

Abstract Article PDF–1.8M

Select item 676942610.

Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self‐renewal and identity

René Rauschmeier, Charlotte Gustafsson, Annika Reinhardt, Noelia A‐Gonzalez, Luigi Tortola, Dilay Cansever, Sethuraman Subramanian, Reshma Taneja, Moritz J Rossner, Michael H Sieweke, Melanie Greter, Robert Månsson, Meinrad Busslinger, Taras Kreslavsky

EMBO J. 2019 Oct 1; 38(19): e101233. Published online 2019 Aug 15. doi: 10.15252/embj.2018101233

PMCID:: PMC6769426

Abstract Article PDF–1.9M

Select item 646531411.

Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression

Yoshinori Makino, Niels H. Jensen, Naoko Yokota, Moritz J. Rossner, Haruhiko Akiyama, Katsuhiko Shirahige, Yuki Okada

Sci Rep. 2019; 9: 6063. Published online 2019 Apr 15. doi: 10.1038/s41598-019-42578-z

PMCID:: PMC6465314

Abstract Article PDF–5.4M

Select item 627609412.

Small Heterodimer Partner Regulates Circadian Cytochromes p450 and Drug-Induced Hepatotoxicity

Tianpeng Zhang, Fangjun Yu, Lianxia Guo, Min Chen, Xue Yuan, Baojian Wu

Theranostics. 2018; 8(19): 5246–5258. Published online 2018 Oct 22. doi: 10.7150/thno.28676

PMCID:: PMC6276094

Abstract Article PDF–1.7M

Select item 591539113.

The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia

Akihiko Numata, Hui Si Kwok, Akira Kawasaki, Jia Li, Qi-Ling Zhou, Jon Kerry, Touati Benoukraf, Deepak Bararia, Feng Li, Erica Ballabio, Marta Tapia, Aniruddha J. Deshpande, Robert S. Welner, Ruud Delwel, Henry Yang, Thomas A. Milne, Reshma Taneja, Daniel G. Tenen

Nat Commun. 2018; 9: 1622. Published online 2018 Apr 24. doi: 10.1038/s41467-018-03854-0

PMCID:: PMC5915391

Abstract Article PDF–2.1M

Select item 582388614.

HDAC4 regulates satellite cell proliferation and differentiation by targeting P21 and Sharp1 genes

Nicoletta Marroncelli, Marzia Bianchi, Marco Bertin, Silvia Consalvi, Valentina Saccone, Marco De Bardi, Pier Lorenzo Puri, Daniela Palacios, Sergio Adamo, Viviana Moresi

Sci Rep. 2018; 8: 3448. Published online 2018 Feb 22. doi: 10.1038/s41598-018-21835-7

PMCID:: PMC5823886

Abstract Article PDF–5.0M

Select item 536383915.

Essential role of the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells

Taras Kreslavsky, Bojan Vilagos, Hiromi Tagoh, Daniela Kostanova Poliakova, Tanja Schwickert, Miriam Wöhner, Markus Jaritz, Siegfried Weiss, Reshma Taneja, Moritz J. Rossner, Meinrad Busslinger

Nat Immunol. Author manuscript; available in PMC 2017 Aug 27.

Published in final edited form as: Nat Immunol. 2017 Apr; 18(4): 442–455. Published online 2017 Feb 27. doi: 10.1038/ni.3694

PMCID:: PMC5363839

Abstract Article PDF–3.5M

Select item 488776216.

Rhythmic expression of DEC2 protein in vitro and in vivo

FUYUKI SATO, YASUTERU MURAGAKI, TAKESHI KAWAMOTO, KATSUMI FUJIMOTO, YUKIO KATO, YANPING ZHANG

Biomed Rep. 2016 Jun; 4(6): 704–710. Published online 2016 Apr 14. doi: 10.3892/br.2016.656

PMCID:: PMC4887762

Abstract Article PDF–991K

Select item 450022217.

Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex

Ali Shahmoradi, Konstantin Radyushkin, Moritz J. Rossner

Proc Natl Acad Sci U S A. 2015 Jul 7; 112(27): E3582–E3589. Published online 2015 Jun 22. doi: 10.1073/pnas.1423989112

PMCID:: PMC4500222

Abstract Article PDF–920K

Select item 431955918.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 420774019.

Mice Lacking the Circadian Modulators SHARP1 and SHARP2 Display Altered Sleep and Mixed State Endophenotypes of Psychiatric Disorders

Paul C. Baier, Magdalena M. Brzózka, Ali Shahmoradi, Lisa Reinecke, Christina Kroos, Sven P. Wichert, Henrik Oster, Michael C. Wehr, Reshma Taneja, Johannes Hirrlinger, Moritz J. Rossner

PLoS One. 2014; 9(10): e110310. Published online 2014 Oct 23. doi: 10.1371/journal.pone.0110310

PMCID:: PMC4207740

Abstract Article PDF–1.1M

Select item 413924320.

Small Ubiquitin-like Modifier (SUMO) Protein-specific Protease 1 De-SUMOylates Sharp-1 Protein and Controls Adipocyte Differentiation

Bingting Liu, Tianshi Wang, Wenhan Mei, Dongdong Li, Rong Cai, Yong Zuo, Jinke Cheng

J Biol Chem. 2014 Aug 8; 289(32): 22358–22364. Published online 2014 Jun 18. doi: 10.1074/jbc.M114.571950

PMCID:: PMC4139243

Abstract Article PDF–1.2M

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