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Select item 100748481.

Glutaredoxin 1 protects lens epithelial cells from epithelial-mesenchymal transition by preventing casein kinase 1α S-glutathionylation during posterior capsular opacification

Chenshuang Li, Xi Chen, Siqi Zhang, Chen Liang, Xiaopan Ma, Ruixue Zhang, Hong Yan

Redox Biol. 2023 Jun; 62: 102676. Published online 2023 Mar 24. doi: 10.1016/j.redox.2023.102676

PMCID:: PMC10074848

Abstract Article PDF–16M

Select item 81215142.

Myeloid cell–derived PROS1 inhibits tumor metastasis by regulating inflammatory and immune responses via IL-10

Avi Maimon, Victor Levi-Yahid, Kerem Ben-Meir, Amit Halpern, Ziv Talmi, Shivam Priya, Gabriel Mizraji, Shani Mistriel-Zerbib, Michael Berger, Michal Baniyash, Sonja Loges, Tal Burstyn-Cohen

J Clin Invest. 2021 May 17; 131(10): e126089. Published online 2021 May 17. doi: 10.1172/JCI126089

PMCID:: PMC8121514

Abstract Article PDF–16M

Select item 72563573.

Platelet protein S limits venous but not arterial thrombosis propensity by controlling coagulation in the thrombus

Sara Calzavarini, Raja Prince-Eladnani, François Saller, Luca Bologna, Laurent Burnier, Anne C. Brisset, Claudia Quarroz, Maria Desiré Reina Caro, Vladimir Ermolayev, Yasuhiro Matsumura, José A. Fernández, Tilman M. Hackeng, John H. Griffin, Anne Angelillo-Scherrer

Blood. 2020 May 28; 135(22): 1969–1982. Prepublished online 2020 Apr 10. doi: 10.1182/blood.2019003630

PMCID:: PMC7256357

Abstract Article

Select item 63839544.

Dual role of DMXL2 in olfactory information transmission and the first wave of spermatogenesis

Clara Gobé, Maëva Elzaiat, Nicolas Meunier, Marjolaine André, Eli Sellem, Patrice Congar, Luc Jouneau, Aurélie Allais-Bonnet, Ikrame Naciri, Bruno Passet, Eric Pailhoux, Maëlle Pannetier

PLoS Genet. 2019 Feb; 15(2): e1007909. Published online 2019 Feb 8. doi: 10.1371/journal.pgen.1007909

PMCID:: PMC6383954

Abstract Article PDF–3.2M

Select item 60167945.

Cell-intrinsic regulation of murine epidermal Langerhans cells by protein S

Yaara Tabib, Nora S. Jaber, Maria Nassar, Tal Capucha, Gabriel Mizraji, Tsipora Nir, Noam Koren, Itay Aizenbud, Avraham Maimon, Luba Eli-Berchoer, Asaf Wilensky, Tal Burstyn-Cohen, Avi-Hai Hovav

Proc Natl Acad Sci U S A. 2018 Jun 19; 115(25): E5736–E5745. Published online 2018 Jun 5. doi: 10.1073/pnas.1800303115

PMCID:: PMC6016794

Abstract Article PDF–1.9M

Select item 59833386.

Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response

Eric Ubil, Laura Caskey, Alisha Holtzhausen, Debra Hunter, Charlotte Story, H. Shelton Earp

J Clin Invest. 2018 Jun 1; 128(6): 2356–2369. Published online 2018 Apr 30. doi: 10.1172/JCI97354

PMCID:: PMC5983338

Abstract Article PDF–9.7M

Select item 59821147.

The Anticoagulant Protein S Targets the Factor IXa Heparin-Binding Exosite to Prevent Thrombosis

William E. Plautz, Vijaya Satish Sekhar Pilli, Brian C. Cooley, Rima Chattopadhyay, Pamela R. Westmark, Todd Getz, David Paul, Wolfgang Bergmeier, John P. Sheehan, Rinku Majumder

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Apr; 38(4): 816–828. Published online 2018 Feb 1. doi: 10.1161/ATVBAHA.117.310588

PMCID:: PMC5982114

Abstract Article PDF–2.6M

Select item 59677708.

Protein S Protects against Podocyte Injury in Diabetic Nephropathy

Fang Zhong, Haibing Chen, Yifan Xie, Evren U. Azeloglu, Chengguo Wei, Weijia Zhang, Zhengzhe Li, Peter Y. Chuang, Belinda Jim, Hong Li, Firas Elmastour, Jalish M. Riyad, Thomas Weber, Hongyu Chen, Yongjun Wang, Aihua Zhang, Weiping Jia, Kyung Lee, John C. He

J Am Soc Nephrol. 2018 May; 29(5): 1397–1410. Published online 2018 Mar 6. doi: 10.1681/ASN.2017030234

PMCID:: PMC5967770

Abstract Article

Select item 59088889.

Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models

Claire E. J. Waterborg, Silke Beermann, Mathijs G. A. Broeren, Miranda B. Bennink, Marije I. Koenders, Peter L. E. M. van Lent, Wim B. van den Berg, Peter M. van der Kraan, Fons A. J. van de Loo

Front Immunol. 2018; 9: 742. Published online 2018 Apr 13. doi: 10.3389/fimmu.2018.00742

PMCID:: PMC5908888

Abstract Article PDF–9.2M

Select item 586523010.

Targeting anticoagulant protein S to improve hemostasis in hemophilia

Raja Prince, Luca Bologna, Mirko Manetti, Daniela Melchiorre, Irene Rosa, Natacha Dewarrat, Silvia Suardi, Poorya Amini, José A. Fernández, Laurent Burnier, Claudia Quarroz, Maria Desiré Reina Caro, Yasuhiro Matsumura, Johanna A. Kremer Hovinga, John H. Griffin, Hans-Uwe Simon, Lidia Ibba-Manneschi, François Saller, Sara Calzavarini, Anne Angelillo-Scherrer

Blood. 2018 Mar 22; 131(12): 1360–1371. Prepublished online 2018 Jan 9. doi: 10.1182/blood-2017-09-800326

PMCID:: PMC5865230

Abstract Article

Select item 583797511.

Macrophage-Derived Protein S Facilitates Apoptotic Polymorphonuclear Cell Clearance by Resolution Phase Macrophages and Supports Their Reprogramming

Delphine Lumbroso, Soaad Soboh, Avi Maimon, Sagie Schif-Zuck, Amiram Ariel, Tal Burstyn-Cohen

Front Immunol. 2018; 9: 358. Published online 2018 Mar 1. doi: 10.3389/fimmu.2018.00358

Correction in:: Front Immunol. 2020; 11: 412281.

PMCID:: PMC5837975

Abstract Article PDF–756K

Select item 550163612.

Plasminogen Tochigi mice exhibit phenotypes similar to wild-type mice under experimental thrombotic conditions

Yuko Tashima, Fumiaki Banno, Toshiyuki Kita, Yasuyuki Matsuda, Hiroji Yanamoto, Toshiyuki Miyata

PLoS One. 2017; 12(7): e0180981. Published online 2017 Jul 7. doi: 10.1371/journal.pone.0180981

PMCID:: PMC5501636

Abstract Article PDF–4.0M

Select item 541144913.

Protein S Negatively Regulates Neural Stem Cell Self-Renewal through Bmi-1 Signaling

Katya Zelentsova-Levytskyi, Ziv Talmi, Ghada Abboud-Jarrous, Tal Capucha, Tamar Sapir, Tal Burstyn-Cohen

Front Mol Neurosci. 2017; 10: 124. Published online 2017 May 2. doi: 10.3389/fnmol.2017.00124

PMCID:: PMC5411449

Abstract Article PDF–3.1M

Select item 535851214.

TAM receptors regulate multiple features of microglial physiology

Lawrence Fourgeaud, Paqui G. Través, Yusuf Tufail, Humberto Leal-Bailey, Erin D. Lew, Patrick G. Burrola, Perri Callaway, Anna Zagórska, Carla V. Rothlin, Axel Nimmerjahn, Greg Lemke

Nature. Author manuscript; available in PMC 2017 Mar 20.

Published in final edited form as: Nature. 2016 Apr 14; 532(7598): 240–244. Published online 2016 Apr 6. doi: 10.1038/nature17630

PMCID:: PMC5358512

Abstract Article PDF–2.9M

Select item 493598415.

The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity

Pamela Y. Chan, Eugenio A. Carrera Silva, Dimitri De Kouchkovsky, Leonel D. Joannas, Liming Hao, Donglei Hu, Scott Huntsman, Celeste Eng, Paula Licona-Limón, Jason S. Weinstein, De’Broski R. Herbert, Joseph E. Craft, Richard A. Flavell, Silvia Repetto, Jorge Correale, Esteban G. Burchard, Dara G. Torgerson, Sourav Ghosh, Carla V. Rothlin

Science. Author manuscript; available in PMC 2016 Jul 7.

Published in final edited form as: Science. 2016 Apr 1; 352(6281): 99–103. doi: 10.1126/science.aaf1358

PMCID:: PMC4935984

Abstract Article PDF–554K

Select item 463511916.

Exacerbated venous thromboembolism in mice carrying a protein S K196E mutation

Fumiaki Banno, Toshiyuki Kita, José A. Fernández, Hiroji Yanamoto, Yuko Tashima, Koichi Kokame, John H. Griffin, Toshiyuki Miyata

Blood. 2015 Nov 5; 126(19): 2247–2253. Prepublished online 2015 Aug 6. doi: 10.1182/blood-2015-06-653162

PMCID:: PMC4635119

Abstract Article

Select item 431955917.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 420682718.

Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities

Erin D Lew, Jennifer Oh, Patrick G Burrola, Irit Lax, Anna Zagórska, Paqui G Través, Joseph Schlessinger, Greg Lemke

eLife. 2014; 3: e03385. Published online 2014 Sep 29. doi: 10.7554/eLife.03385

PMCID:: PMC4206827

Abstract Article PDF–8.8M

Select item 401723719.

T cell-derived Protein S engages TAM signaling in Dendritic Cells to control the magnitude of the immune response

Eugenio A. Carrera Silva, Pamela Y. Chan, Leonel Joannas, Andrea E. Errasti, Nicola Gagliani, Lidia Bosurgi, Maurice Jabbour, Anthony Perry, Faye Smith-Chakmakova, Daniel Mucida, Hilde Cheroutre, Tal Burstyn-Cohen, Jonathan A. Leighton, Greg Lemke, Sourav Ghosh, Carla V. Rothlin

Immunity. Author manuscript; available in PMC 2014 May 12.

Published in final edited form as: Immunity. 2013 Jul 25; 39(1): 160–170. Published online 2013 Jul 11. doi: 10.1016/j.immuni.2013.06.010

PMCID:: PMC4017237

Abstract Article PDF–1.7M

Select item 357241020.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

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