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Items: 1 to 20 of 35

1.
Synaptic neoteny of human cortical neurons requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition
Baptiste Libé-Philippot, Ryohei Iwata, Aleksandra J. Recupero, Keimpe Wierda, Sergio Bernal Garcia, Luke Hammond, Anja van Benthem, Ridha Limame, Martyna Ditkowska, Sofie Beckers, Vaiva Gaspariunaite, Eugénie Peze-Heidsieck, Daan Remans, Cécile Charrier, Tom Theys, Franck Polleux, Pierre Vanderhaeghen
Neuron. 2024 Nov 6; 112(21): 3602–3617.e9. doi: 10.1016/j.neuron.2024.08.021
PMCID:
PMC11546603
AbstractArticle
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
4.
A human-specific modifier of cortical connectivity and circuit function
Ewoud R.E. Schmidt, Hanzhi T. Zhao, Jung M. Park, Mario Dipoppa, Mauro M. Monsalve-Mercado, Jacob B. Dahan, Chris C. Rodgers, Amélie Lejeune, Elizabeth M. C. Hillman, Kenneth D. Miller, Randy M. Bruno, Franck Polleux
Nature. Author manuscript; available in PMC 2022 Jun 2.
Published in final edited form as: Nature. 2021 Nov; 599(7886): 640–644. Published online 2021 Oct 27. doi: 10.1038/s41586-021-04039-4
Correction in:
Nature. 2022 Jan 6
PMCID:
PMC9161439
AbstractArticlePDF–5.1M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance
Manuel Rogg, Jasmin I. Maier, Robert Dotzauer, Nadine Artelt, Oliver Kretz, Martin Helmstädter, Ahmed Abed, Alena Sammarco, August Sigle, Dominik Sellung, Patrick Dinse, Karoline Reiche, Mako Yasuda-Yamahara, Martin L. Biniossek, Gerd Walz, Martin Werner, Nicole Endlich, Oliver Schilling, Tobias B. Huber, Christoph Schell
J Am Soc Nephrol. 2021 Mar; 32(3): 563–579. Published online 2021 Jan 29. doi: 10.1681/ASN.2020081126
PMCID:
PMC7920176
AbstractArticle
8.
Rac1 inhibition via Srgap2 restrains inflammatory osteoclastogenesis and limits the clastokine, SLIT3
Bongjin Shin, Justine Kupferman, Ewoud Schmidt, Franck Polleux, Anne M. Delany, Sun-Kyeong Lee
J Bone Miner Res. Author manuscript; available in PMC 2020 Nov 26.
Published in final edited form as: J Bone Miner Res. 2020 Apr; 35(4): 789–800. Published online 2020 Jan 9. doi: 10.1002/jbmr.3945
PMCID:
PMC7690287
AbstractArticlePDF–2.3M
9.
Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome
Abigail U. Carbonell, Chang Hoon Cho, Jaafar O. Tindi, Pamela A. Counts, Juliana C. Bates, Hediye Erdjument-Bromage, Svetlana Cvejic, Alana Iaboni, Ifat Kvint, Jenny Rosensaft, Ehud Banne, Evdokia Anagnostou, Thomas A. Neubert, Stephen W. Scherer, Sophie Molholm, Bryen A. Jordan
Nat Commun. 2019; 10: 3529. Published online 2019 Aug 6. doi: 10.1038/s41467-019-11437-w
PMCID:
PMC6684583
AbstractArticlePDF–2.2M
10.
Leukocyte cytoskeleton polarization is initiated by plasma membrane curvature from cell attachment
Chunguang Ren, Qianying Yuan, Martha Braun, Xia Zhang, Björn Petri, Jiasheng Zhang, Dongjoo Kim, Julia Guez-Haddad, Wenzhi Xue, Weijun Pan, Rong Fan, Paul Kubes, Zhaoxia Sun, Yarden Opatowsky, Franck Polleux, Erdem Karatekin, Wenwen Tang, Dianqing Wu
Dev Cell. Author manuscript; available in PMC 2020 Apr 22.
Published in final edited form as: Dev Cell. 2019 Apr 22; 49(2): 206–219.e7. Published online 2019 Mar 28. doi: 10.1016/j.devcel.2019.02.023
PMCID:
PMC6482112
AbstractArticlePDF–2.9M
11.
Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry
Maria del Mar Masdeu, Beatriz G. Armendáriz, Anna La Torre, Eduardo Soriano, Ferran Burgaya, Jesús Mariano Ureña
Oncotarget. 2017 Nov 24; 8(60): 101146–101157. Published online 2017 Sep 15. doi: 10.18632/oncotarget.20929
PMCID:
PMC5731862
AbstractArticlePDF–5.4M
12.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
13.
Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling
Brent Wilkinson, Jing Li, Marcelo P. Coba
Sci Rep. 2017; 7: 5272. Published online 2017 Jul 13. doi: 10.1038/s41598-017-05588-3
PMCID:
PMC5509740
AbstractArticlePDF–4.6M
14.
SRGAP2 and its human-specific paralog co-regulate the development of excitatory and inhibitory synapses
Matteo Fossati, Rocco Pizzarelli, Ewoud R. Schmidt, Justine V. Kupferman, David Stroebel, Franck Polleux, Cécile Charrier
Neuron. Author manuscript; available in PMC 2017 Jul 20.
Published in final edited form as: Neuron. 2016 Jul 20; 91(2): 356–369. Published online 2016 Jun 30. doi: 10.1016/j.neuron.2016.06.013
PMCID:
PMC5385270
AbstractArticlePDF–2.3M
15.
Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma
Tracy A. Marko, Ghaidan A. Shamsan, Elizabeth N. Edwards, Paige E. Hazelton, Susan K. Rathe, Ingrid Cornax, Paula R. Overn, Jyotika Varshney, Brandon J. Diessner, Branden S. Moriarity, M. Gerard O’Sullivan, David J. Odde, David A. Largaespada
Sci Rep. 2016; 6: 39059. Published online 2016 Dec 14. doi: 10.1038/srep39059
PMCID:
PMC5155223
AbstractArticlePDF–1.3M
16.
The Inverse F-BAR Domain Protein srGAP2 Acts through srGAP3 to Modulate Neuronal Differentiation and Neurite Outgrowth of Mouse Neuroblastoma Cells
Yue Ma, Ya-Jing Mi, Yun-Kai Dai, Hua-Lin Fu, Da-Xiang Cui, Wei-Lin Jin
PLoS One. 2013; 8(3): e57865. Published online 2013 Mar 7. doi: 10.1371/journal.pone.0057865
PMCID:
PMC3591447
AbstractArticlePDF–1.9M
17.
Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation
Cécile Charrier, Kaumudi Joshi, Jaeda Coutinho-Budd, Ji-Eun Kim, Nelle Lambert, Jacqueline de Marchena, Wei-Lin Jin, Pierre Vanderhaeghen, Anirvan Ghosh, Takayuki Sassa, Franck Polleux
Cell. Author manuscript; available in PMC 2013 May 11.
Published in final edited form as: Cell. 2012 May 11; 149(4): 923–935. Published online 2012 May 3. doi: 10.1016/j.cell.2012.03.034
PMCID:
PMC3357949
AbstractArticlePDF–6.1M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Evidence for a Role of srGAP3 in the Positioning of Commissural Axons within the Ventrolateral Funiculus of the Mouse Spinal Cord
Claire Bacon, Volker Endris, Irwin Andermatt, Vera Niederkofler, Robert Waltereit, Dusan Bartsch, Esther T. Stoeckli, Gudrun Rappold
PLoS One. 2011; 6(5): e19887. Published online 2011 May 31. doi: 10.1371/journal.pone.0019887
PMCID:
PMC3104994
AbstractArticlePDF–2.9M
20.
Bi-modal Regulation of a Formin by srGAP2
Frank M. Mason, Ernest G. Heimsath, Henry N. Higgs, Scott H. Soderling
J Biol Chem. 2011 Feb 25; 286(8): 6577–6586. Published online 2010 Dec 9. doi: 10.1074/jbc.M110.190397
PMCID:
PMC3057853
AbstractArticlePDF–3.1M

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