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Select item 114527061.

Evolution of the conformational dynamics of the molecular chaperone Hsp90

Stefan Riedl, Ecenaz Bilgen, Ganesh Agam, Viivi Hirvonen, Alexander Jussupow, Franziska Tippl, Maximilian Riedl, Andreas Maier, Christian F. W. Becker, Ville R. I. Kaila, Don C. Lamb, Johannes Buchner

Nat Commun. 2024; 15: 8627. Published online 2024 Oct 4. doi: 10.1038/s41467-024-52995-y

PMCID:: PMC11452706

Abstract Article PDF–3.8M

Select item 114465482.

The zinc-finger transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis to cytoplasmic decay

Moran Kelbert, Antonio Jordán-Pla, Lola de Miguel-Jiménez, José García-Martínez, Michael Selitrennik, Adi Guterman, Noa Henig, Sander Granneman, José E Pérez-Ortín, Sebastián Chávez, Mordechai Choder

eLife. 2024; 12: RP90766. Published online 2024 Oct 2. doi: 10.7554/eLife.90766

PMCID:: PMC11446548

Abstract Article PDF–7.1M

Select item 114236783.

An APEX2-based proximity-dependent biotinylation assay with temporal specificity to study protein interactions during autophagy in the yeast Saccharomyces cerevisiae

Yasmina Filali-Mouncef, Alexandre Leytens, Prado Vargas Duarte, Mattia Zampieri, Jörn Dengjel, Fulvio Reggiori

Autophagy. 2024; 20(10): 2323–2337. Published online 2024 Jul 3. doi: 10.1080/15548627.2024.2366749

PMCID:: PMC11423678

Abstract Article PDF–1.7M

Select item 111547084.

Identification of a chaperone-code responsible for Rad51-mediated genome repair

Khushboo Rani, Akanksha Gotmare, Andreas Maier, Ruchira Menghal, Nashat Akhtar, Nupur Fangaria, Johannes Buchner, Sunanda Bhattacharyya

J Biol Chem. 2024 Jun; 300(6): 107342. Published online 2024 May 3. doi: 10.1016/j.jbc.2024.107342

PMCID:: PMC11154708

Abstract Article PDF–3.4M

Select item 111519325.

Quantitative proteomic analysis reveals unique Hsp90 cycle-dependent client interactions

Erick I Rios, Davi Gonçalves, Kevin A Morano, Jill L Johnson

Genetics. 2024 Jun; 227(2): iyae057. Published online 2024 Apr 12. doi: 10.1093/genetics/iyae057

PMCID:: PMC11151932

Abstract Article PDF–700K

Select item 110241856.

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Victor E. Cruz, Christine S. Weirich, Nagesh Peddada, Jan P. Erzberger

Nat Commun. 2024; 15: 3296. Published online 2024 Apr 17. doi: 10.1038/s41467-024-47616-7

PMCID:: PMC11024185

Abstract Article PDF–7.4M

Select item 108724777.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 108687278.

Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates

Asif Ali, Rania Garde, Olivia C. Schaffer, Jared A. M. Bard, Kabir Husain, Samantha Keyport Kik, Kathleen A. Davis, Sofia Luengo-Woods, Maya G. Igarashi, D. Allan Drummond, Allison H. Squires, David Pincus

Nat Cell Biol. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: Nat Cell Biol. 2023 Nov; 25(11): 1691–1703. Published online 2023 Oct 16. doi: 10.1038/s41556-023-01253-2

PMCID:: PMC10868727

Abstract Article PDF–7.0M

Select item 107988589.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 1077004210.

Nuclear Hsp104 safeguards the dormant translation machinery during quiescence

Verena Kohler, Andreas Kohler, Lisa Larsson Berglund, Xinxin Hao, Sarah Gersing, Axel Imhof, Thomas Nyström, Johanna L. Höög, Martin Ott, Claes Andréasson, Sabrina Büttner

Nat Commun. 2024; 15: 315. Published online 2024 Jan 5. doi: 10.1038/s41467-023-44538-8

PMCID:: PMC10770042

Abstract Article PDF–5.1M

Select item 1070013811.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 1052734712.

J-domain proteins form binary complexes with Hsp90 and ternary complexes with Hsp90 and Hsp70

Anushka C. Wickramaratne, Jui-Yun Liao, Shannon M. Doyle, Joel R. Hoskins, Gabrielle Puller, Madison L. Scott, John Paul Alao, Ikponwmosa Obaseki, Jerry C. Dinan, Tapan K. Maity, Lisa M. Jenkins, Andrea N. Kravats, Sue Wickner

J Mol Biol. Author manuscript; available in PMC 2024 Sep 1.

Published in final edited form as: J Mol Biol. 2023 Sep 1; 435(17): 168184. Published online 2023 Jun 20. doi: 10.1016/j.jmb.2023.168184

PMCID:: PMC10527347

Abstract Article PDF–4.1M

Select item 1051470013.

Xrn1 biochemically associates with eisosome proteins after the post diauxic shift in yeast

Baptiste Courtin, Abdelkader Namane, Maite Gomard, Laura Meyer, Alain Jacquier, Micheline Fromont-Racine

MicroPubl Biol. 2023; 2023: 10.17912/micropub.biology.000926. Published online 2023 Sep 7. doi: 10.17912/micropub.biology.000926

PMCID:: PMC10514700

Abstract Article PDF–1.7M

Select item 1024683814.

Hsp90 mutants with distinct defects provide novel insights into cochaperone regulation of the folding cycle

Rebecca Mercier, Danielle Yama, Paul LaPointe, Jill L. Johnson

PLoS Genet. 2023 May; 19(5): e1010772. Published online 2023 May 25. doi: 10.1371/journal.pgen.1010772

PMCID:: PMC10246838

Abstract Article PDF–2.5M

Select item 1020864515.

Mitochondrial protein import clogging as a mechanism of disease

Liam P Coyne, Xiaowen Wang, Jiyao Song, Ebbing de Jong, Karin Schneider, Paul T Massa, Frank A Middleton, Thomas Becker, Xin Jie Chen

eLife. 2023; 12: e84330. Published online 2023 May 2. doi: 10.7554/eLife.84330

PMCID:: PMC10208645

Abstract Article PDF–12M

Select item 1014880916.

Nucleotide exchange is sufficient for Hsp90 functions in vivo

Michael Reidy, Kevin Garzillo, Daniel C. Masison

Nat Commun. 2023; 14: 2489. Published online 2023 Apr 29. doi: 10.1038/s41467-023-38230-0

PMCID:: PMC10148809

Abstract Article PDF–4.9M

Select item 1006833617.

MitoStores: chaperone‐controlled protein granules store mitochondrial precursors in the cytosol

Lena Krämer, Niko Dalheimer, Markus Räschle, Zuzana Storchová, Jan Pielage, Felix Boos, Johannes M Herrmann

EMBO J. 2023 Apr; 42(7): e112309. Published online 2023 Jan 27. doi: 10.15252/embj.2022112309

PMCID:: PMC10068336

Abstract Article PDF–3.9M

Select item 988117618.

The S. cerevisiae m⁶A-reader Pho92 promotes timely meiotic recombination by controlling key methylated transcripts

Jérémy Scutenaire, Damien Plassard, Mélody Matelot, Tommaso Villa, Julie Zumsteg, Domenico Libri, Bertrand Séraphin

Nucleic Acids Res. 2023 Jan 25; 51(2): 517–535. Published online 2022 Aug 8. doi: 10.1093/nar/gkac640

PMCID:: PMC9881176

Abstract Article PDF–7.3M

Select item 964562719.

Ydj1 interaction at nucleotide-binding-domain of yeast Ssa1 impacts Hsp90 collaboration and client maturation

Deepika Gaur, Navinder Kumar, Abhirupa Ghosh, Prashant Singh, Pradeep Kumar, Jyoti Guleria, Satinderdeep Kaur, Nikhil Malik, Sudipto Saha, Thomas Nystrom, Deepak Sharma

PLoS Genet. 2022 Nov; 18(11): e1010442. Published online 2022 Nov 9. doi: 10.1371/journal.pgen.1010442

PMCID:: PMC9645627

Abstract Article PDF–2.7M

Select item 963802820.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536