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Select item 110939691.

ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1

Margaret Solon, Nianfeng Ge, Shannon Hambro, Susan Haller, Jian Jiang, Miriam Baca, Jessica Preston, Allie Maltzman, Katherine E. Wickliffe, Yuxin Liang, Rohit Reja, Dorothee Nickles, Kim Newton, Joshua D. Webster

Cell Death Differ. 2024 May; 31(5): 672–682. Published online 2024 Mar 28. doi: 10.1038/s41418-024-01286-6

PMCID:: PMC11093969

Abstract Article PDF–5.5M

Select item 109876622.

Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin

Uttkarsh Ayyangar, Aneesh Karkhanis, Heather Tay, Aliya Farissa Binte Afandi, Oindrila Bhattacharjee, Lalitha KS, Sze Han Lee, James Chan, Srikala Raghavan

EMBO J. 2024 Apr; 43(7): 1113–1134. Published online 2024 Feb 28. doi: 10.1038/s44318-024-00039-y

PMCID:: PMC10987662

Abstract Article PDF–12M

Select item 109453403.

Dynamic pathological analysis reveals a protective role against skin fibrosis for TREM2-dependent macrophages

Yunsheng Liang, Yongfei Hu, Jun Zhang, Haosen Song, Xiaoqian Zhang, Yishan Chen, Yu Peng, Lihua Sun, Yuzhe Sun, Ruzeng Xue, Suyun Ji, Chuanwei Li, Zhili Rong, Bin Yang, Yingping Xu

Theranostics. 2024; 14(5): 2232–2245. Published online 2024 Mar 11. doi: 10.7150/thno.94121

PMCID:: PMC10945340

Abstract Article PDF–12M

Select item 109130284.

Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon

Jorge O. Múnera, Daniel O. Kechele, Carine Bouffi, Na Qu, Ran Jing, Pritiprasanna Maity, Jacob R. Enriquez, Lu Han, Ian Campbell, Maxime M. Mahe, Heather A. McCauley, Xinghao Zhang, Nambirajan Sundaram, Jonathan R. Hudson, Adrian Zarsozo-Lacoste, Suman Pradhan, Kentaro Tominaga, J. Guillermo Sanchez, Alison A. Weiss, Praneet Chatuvedi, Jason R. Spence, Mariam Hachimi, Trista North, George Q. Daley, Christopher N. Mayhew, Yueh-Chiang Hu, Takanori Takebe, Michael A. Helmrath, James M. Wells

Cell Stem Cell. Author manuscript; available in PMC 2024 Mar 5.

Published in final edited form as: Cell Stem Cell. 2023 Nov 2; 30(11): 1434–1451.e9. doi: 10.1016/j.stem.2023.10.002

PMCID:: PMC10913028

Abstract Article PDF–4.3M

Select item 108910745.

Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo

Zaniah N. Gonzalez Galofre, Alastair M. Kilpatrick, Madalena Marques, Diana Sá da Bandeira, Telma Ventura, Mario Gomez Salazar, Léa Bouilleau, Yvan Marc, Ana B. Barbosa, Fiona Rossi, Mariana Beltran, Harmen J. G. van de Werken, Wilfred F. J. van IJcken, Neil C. Henderson, Stuart J. Forbes, Mihaela Crisan

Nat Commun. 2024; 15: 1653. Published online 2024 Feb 23. doi: 10.1038/s41467-024-44913-z

PMCID:: PMC10891074

Abstract Article PDF–30M

Select item 107897426.

ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function

Yue Zhu, Qinqin Wang, Xinyu Xie, Cuihong Ma, Yuemei Qiao, Yu Zhang, Yanjun Wu, Yuan Gao, Jing Jiang, Xin Liu, Jianfeng Chen, Chen Li, Gaoxiang Ge

Cell Death Dis. 2024 Jan; 15(1): 55. Published online 2024 Jan 15. doi: 10.1038/s41419-024-06441-y

PMCID:: PMC10789742

Abstract Article PDF–8.7M

Select item 107211837.

Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration

Viola Kretschmer, Sandra Schneider, Peter Andreas Matthiessen, Dominik Reichert, Nathan Hotaling, Gunnar Glasßer, Ingo Lieberwirth, Kapil Bharti, Rossella De Cegli, Ivan Conte, Emeline F. Nandrot, Helen Louise May-Simera

PLoS Biol. 2023 Dec; 21(12): e3002402. Published online 2023 Dec 4. doi: 10.1371/journal.pbio.3002402

PMCID:: PMC10721183

Abstract Article PDF–2.4M

Select item 106465518.

cIAPs control RIPK1 kinase activity‐dependent and ‐independent cell death and tissue inflammation

Fabian Schorn, J Paul Werthenbach, Mattes Hoffmann, Mila Daoud, Johanna Stachelscheid, Lars M Schiffmann, Ximena Hildebrandt, Su Ir Lyu, Nieves Peltzer, Alexander Quaas, Domagoj Vucic, John Silke, Manolis Pasparakis, Hamid Kashkar

EMBO J. 2023 Nov; 42(22): e113614. Published online 2023 Oct 4. doi: 10.15252/embj.2023113614

PMCID:: PMC10646551

Abstract Article PDF–3.3M

Select item 106028899.

P53 independent pathogenic mechanisms contribute to BubR1 microcephaly

Noelle A. Sterling, Bethany K. Terry, Julia M. McDonnell, Seonhee Kim

Front Cell Dev Biol. 2023; 11: 1282182. Published online 2023 Oct 12. doi: 10.3389/fcell.2023.1282182

PMCID:: PMC10602889

Abstract Article PDF–7.3M

Select item 1057115910.

Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function

Lorenzo M. Fernandes, Jeffrey Tresemer, Jing Zhang, Jonathan J. Rios, Joshua P. Scallan, Michael T. Dellinger

Front Cell Dev Biol. 2023; 11: 1276333. Published online 2023 Sep 25. doi: 10.3389/fcell.2023.1276333

PMCID:: PMC10571159

Abstract Article PDF–14M

Select item 1049987911.

Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development

Yongzhen Lai, Yan Guo, Caiyu Liao, Chuanqing Mao, Jing Liu, Chengyan Ren, Wen Yang, Lin Luo, Weihui Chen

Sci Rep. 2023; 13: 15170. Published online 2023 Sep 13. doi: 10.1038/s41598-023-42423-4

PMCID:: PMC10499879

Abstract Article PDF–6.8M

Select item 1048047712.

Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-5

Norika Liu, Naofumi Kawahira, Yasuhiro Nakashima, Haruko Nakano, Akiyasu Iwase, Yasunobu Uchijima, Mei Wang, Sean M. Wu, Susumu Minamisawa, Hiroki Kurihara, Atsushi Nakano

Nat Commun. 2023; 14: 5398. Published online 2023 Sep 5. doi: 10.1038/s41467-023-41039-6

PMCID:: PMC10480477

Abstract Article PDF–2.4M

Select item 1011050113.

Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling

Dhwani N. Rupani, Fredrik I. Thege, Vidhi Chandra, Hajar Rajaei, Robert W. Cowan, Sonja M. Wörmann, Olivereen Le Roux, Prerna Malaney, Sara L. Manning, Jack Hashem, Jennifer Bailey-Lundberg, Andrew D. Rhim, Florencia McAllister

Development. 2023 Jan 15; 150(2): dev201097. Published online 2023 Jan 16. doi: 10.1242/dev.201097

PMCID:: PMC10110501

Abstract Article

Select item 1001770314.

Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions

Xiaowei Gu, Anna Heinrich, Shu-Yun Li, Tony DeFalco

Nat Commun. 2023; 14: 1439. Published online 2023 Mar 15. doi: 10.1038/s41467-023-37199-0

PMCID:: PMC10017703

Abstract Article PDF–16M

Select item 981611115.

An entosis-like process induces mitotic disruption in Pals1 microcephaly pathogenesis

Noelle A. Sterling, Jun Young Park, Raehee Park, Seo-Hee Cho, Seonhee Kim

Nat Commun. 2023; 14: 82. Published online 2023 Jan 5. doi: 10.1038/s41467-022-35719-y

PMCID:: PMC9816111

Abstract Article PDF–7.8M

Select item 975220016.

Mouse placenta fetal macrophages arise from endothelial cells outside the placenta

Xiaowen Chen, Alan T. Tang, Joanna Tober, Jisheng Yang, N. Adrian Leu, Stephanie Sterling, Mei Chen, Yiqing Yang, Patricia Mericko-Ishizuka, Nancy A. Speck, Mark L. Kahn

Dev Cell. Author manuscript; available in PMC 2023 Dec 5.

Published in final edited form as: Dev Cell. 2022 Dec 5; 57(23): 2652–2660.e3. doi: 10.1016/j.devcel.2022.11.003

PMCID:: PMC9752200

Abstract Article PDF–1.3M

Select item 971253617.

Deciphering the heterogeneity of the Lyve1⁺ perivascular macrophages in the mouse brain

C. Siret, M. van Lessen, J. Bavais, H. W. Jeong, S. K. Reddy Samawar, K. Kapupara, S. Wang, M. Simic, L. de Fabritus, A. Tchoghandjian, M. Fallet, H. Huang, S. Sarrazin, M. H. Sieweke, R. Stumm, L. Sorokin, R. H. Adams, S. Schulte-Merker, F. Kiefer, S. A. van de Pavert

Nat Commun. 2022; 13: 7366. Published online 2022 Nov 30. doi: 10.1038/s41467-022-35166-9

PMCID:: PMC9712536

Abstract Article PDF–10M

Select item 959260918.

Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice

Tian Zhou, Yuxin Li, Xiaoyu Li, Fanzhuo Zeng, Yanxia Rao, Yang He, Yafei Wang, Meizhen Liu, Dali Li, Zhen Xu, Xin Zhou, Siling Du, Fugui Niu, Jiyun Peng, Xifan Mei, Sheng-Jian Ji, Yousheng Shu, Wei Lu, Feifan Guo, Tianzhun Wu, Ti-Fei Yuan, Ying Mao, Bo Peng

Nat Commun. 2022; 13: 6233. Published online 2022 Oct 24. doi: 10.1038/s41467-022-33932-3

PMCID:: PMC9592609

Abstract Article PDF–11M

Select item 957673519.

Brain milieu induces early microglial maturation through the BAX-Notch axis

Fangying Zhao, Jiangyong He, Jun Tang, Nianfei Cui, Yanyan Shi, Zhifan Li, Shengnan Liu, Yazhou Wang, Ming Ma, Congjian Zhao, Lingfei Luo, Li Li

Nat Commun. 2022; 13: 6117. Published online 2022 Oct 17. doi: 10.1038/s41467-022-33836-2

PMCID:: PMC9576735

Abstract Article PDF–8.8M

Select item 954690620.

Vascular smooth muscle RhoA counteracts abdominal aortic aneurysm formation by modulating MAP4K4 activity

Md Rasel Molla, Akio Shimizu, Masahiro Komeno, Nor Idayu A. Rahman, Joanne Ern Chi Soh, Le Kim Chi Nguyen, Mahbubur Rahman Khan, Wondwossen Wale Tesega, Si Chen, Xiaoling Pang, Miki Tanaka-Okamoto, Noriyuki Takashima, Akira Sato, Tomoaki Suzuki, Hisakazu Ogita

Commun Biol. 2022; 5: 1071. Published online 2022 Oct 7. doi: 10.1038/s42003-022-04042-z

PMCID:: PMC9546906

Abstract Article PDF–5.3M

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