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Items: 1 to 20 of 23

1.
TDP-1 and FUST-1 co-inhibit exon inclusion and control fertility together with transcriptional regulation
Morgan Taylor, Olivia Marx, Adam Norris
Nucleic Acids Res. 2023 Oct 13; 51(18): 9610–9628. Published online 2023 Aug 17. doi: 10.1093/nar/gkad665
PMCID:
PMC10570059
AbstractArticlePDF–2.7M
2.
Nucleoporin foci are stress‐sensitive condensates dispensable for C. elegans nuclear pore assembly
Laura Thomas, Basma Taleb Ismail, Peter Askjaer, Geraldine Seydoux
EMBO J. 2023 Jul; 42(13): e112987. Published online 2023 May 31. doi: 10.15252/embj.2022112987
PMCID:
PMC10308366
AbstractArticlePDF–3.2M
3.
Generation of a C. elegans tdp-1 null allele and humanized TARDBP containing human disease-variants.
Jeremy Lins, Trisha J Brock, Chris E Hopkins, Anne C Hart
MicroPubl Biol. 2023; 2023: 10.17912/micropub.biology.000693. Published online 2023 Jun 6. doi: 10.17912/micropub.biology.000693
PMCID:
PMC10282831
AbstractArticlePDF–516K
4.
TDP-43 promotes tau accumulation and selective neurotoxicity in bigenic Caenorhabditis elegans
Caitlin S. Latimer, Jade G. Stair, Joshua C. Hincks, Heather N. Currey, Thomas D. Bird, C. Dirk Keene, Brian C. Kraemer, Nicole F. Liachko
Dis Model Mech. 2022 Apr 1; 15(4): dmm049323. Published online 2022 Apr 27. doi: 10.1242/dmm.049323
PMCID:
PMC9066518
AbstractArticle
5.
Human Ubiquilin 2 and TDP-43 copathology drives neurodegeneration in transgenic Caenorhabditis elegans
Aleen D Saxton, Brian C Kraemer
G3 (Bethesda) 2021 Aug; 11(8): jkab158. Published online 2021 May 8. doi: 10.1093/g3journal/jkab158
PMCID:
PMC8496285
AbstractArticlePDF–1.1M
6.
Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules
Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus
eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833
PMCID:
PMC8331183
AbstractArticlePDF–8.5M
7.
EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes
Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili
Nat Methods. Author manuscript; available in PMC 2021 Mar 26.
Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4
PMCID:
PMC7995176
AbstractArticlePDF–1.0M
8.
Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration
Veronica H Ryan, Theodora M Perdikari, Mandar T Naik, Camillo F Saueressig, Jeremy Lins, Gregory L Dignon, Jeetain Mittal, Anne C Hart, Nicolas L Fawzi
EMBO J. 2021 Feb 1; 40(3): e105001. Published online 2020 Dec 22. doi: 10.15252/embj.2020105001
PMCID:
PMC7849316
AbstractArticlePDF–2.6M
9.
An Intramolecular Salt Bridge Linking TDP43 RNA Binding, Protein Stability, and TDP43-Dependent Neurodegeneration
Brittany N. Flores, Xingli Li, Ahmed M. Malik, Jose Martinez, Asim A. Beg, Sami J. Barmada
Cell Rep. Author manuscript; available in PMC 2019 May 3.
Published in final edited form as: Cell Rep. 2019 Apr 23; 27(4): 1133–1150.e8. doi: 10.1016/j.celrep.2019.03.093
PMCID:
PMC6499398
AbstractArticlePDF–2.5M
10.
Heat shock in C. elegans induces downstream of gene transcription and accumulation of double-stranded RNA
Marko Melnick, Patrick Gonzales, Joseph Cabral, Mary A. Allen, Robin D. Dowell, Christopher D. Link
PLoS One. 2019; 14(4): e0206715. Published online 2019 Apr 8. doi: 10.1371/journal.pone.0206715
PMCID:
PMC6453478
AbstractArticlePDF–2.7M
11.
Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects
Joy Mitra, Erika N. Guerrero, Pavana M. Hegde, Nicole F. Liachko, Haibo Wang, Velmarini Vasquez, Junling Gao, Arvind Pandey, J. Paul Taylor, Brian C. Kraemer, Ping Wu, Istvan Boldogh, Ralph M. Garruto, Sankar Mitra, K. S. Rao, Muralidhar L. Hegde
Proc Natl Acad Sci U S A. 2019 Mar 5; 116(10): 4696–4705. Published online 2019 Feb 15. doi: 10.1073/pnas.1818415116
PMCID:
PMC6410842
AbstractArticlePDF–2.0M
12.
OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes
Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye
Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307
PMCID:
PMC6216590
AbstractArticlePDF–1.4M
13.
The Caenorhabditis elegans Ortholog of TDP-43 Regulates the Chromatin Localization of the Heterochromatin Protein 1 Homolog HPL-2
Tassa K. Saldi, Patrick Gonzales, Alfonso Garrido-Lecca, Vishantie Dostal, Christine M. Roberts, Leonard Petrucelli, Christopher D. Link
Mol Cell Biol. 2018 Aug 1; 38(15): e00668-17. Prepublished online 2018 May 14. Published online 2018 Jul 16. doi: 10.1128/MCB.00668-17
PMCID:
PMC6048318
AbstractArticlePDF–2.3M
14.
CRISPR-mediated genetic interaction profiling identifies RNA binding proteins controlling metazoan fitness
Adam D Norris, Xicotencatl Gracida, John A Calarco
eLife. 2017; 6: e28129. Published online 2017 Jul 18. doi: 10.7554/eLife.28129
PMCID:
PMC5544425
AbstractArticlePDF–1.7M
15.
TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA
Tassa K Saldi, Peter EA Ash, Gavin Wilson, Patrick Gonzales, Alfonso Garrido-Lecca, Christine M Roberts, Vishantie Dostal, Tania F Gendron, Lincoln D Stein, Thomas Blumenthal, Leonard Petrucelli, Christopher D Link
EMBO J. 2014 Dec 17; 33(24): 2947–2966. Published online 2014 Nov 12. doi: 10.15252/embj.201488740
PMCID:
PMC4282642
AbstractArticlePDF–3.6M
16.
RNA-Processing Protein TDP-43 Regulates FOXO-Dependent Protein Quality Control in Stress Response
Tao Zhang, Gerard Baldie, Goran Periz, Jiou Wang
PLoS Genet. 2014 Oct; 10(10): e1004693. Published online 2014 Oct 16. doi: 10.1371/journal.pgen.1004693
PMCID:
PMC4199500
AbstractArticlePDF–1.1M
17.
Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion
Lei-Lei Jiang, Mei-Xia Che, Jian Zhao, Chen-Jie Zhou, Mu-Yun Xie, Hai-Yin Li, Jian-Hua He, Hong-Yu Hu
J Biol Chem. 2013 Jul 5; 288(27): 19614–19624. Published online 2013 May 20. doi: 10.1074/jbc.M113.463828
PMCID:
PMC3707662
AbstractArticlePDF–2.4M
18.
TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in Caenorhabditis elegans
Alexandra Vaccaro, Arnaud Tauffenberger, Peter E. A. Ash, Yari Carlomagno, Leonard Petrucelli, J. Alex Parker
PLoS Genet. 2012 Jul; 8(7): e1002806. Published online 2012 Jul 5. doi: 10.1371/journal.pgen.1002806
PMCID:
PMC3390363
AbstractArticlePDF–2.8M
19.
Caenorhabditis elegans RNA-processing Protein TDP-1 Regulates Protein Homeostasis and Life Span
Tao Zhang, Ho-Yon Hwang, Haiping Hao, Conover Talbot, Jr., Jiou Wang
J Biol Chem. 2012 Mar 9; 287(11): 8371–8382. Published online 2012 Jan 9. doi: 10.1074/jbc.M111.311977
PMCID:
PMC3318719
AbstractArticlePDF–2.1M
20.
OrthoList: A Compendium of C. elegans Genes with Human Orthologs
Daniel D. Shaye, Iva Greenwald
PLoS One. 2011; 6(5): e20085. Published online 2011 May 25. doi: 10.1371/journal.pone.0020085
Correction in:
PLoS One. 2014; 9(1): 10.1371/annotation/f5ffb738-a176-4a43-b0e0-249cdea45fe0.
PMCID:
PMC3102077
AbstractArticlePDF–530K

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