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Items: 1 to 20 of 53

1.
One of these strains is not like the others: C. elegans DW102 has an altered dependence on brc-1 and brd-1 for regulation of cyp gene transcription
Ishor Thapa, Marlo K. Sellin Jeffries, Mikaela D. Stewart
MicroPubl Biol. 2024; 2024: 10.17912/micropub.biology.001152. Published online 2024 Jun 4. doi: 10.17912/micropub.biology.001152
PMCID:
PMC11184413
AbstractArticlePDF–267K
2.
PP2A inhibition causes synthetic lethality in BRCA2-mutated prostate cancer models via spindle assembly checkpoint reactivation
Jian Wang, Yuke Chen, Shiwei Li, Wanchang Liu, Xiao Albert Zhou, Yefei Luo, Zhanzhan Xu, Yundong Xiong, Kaiqi Cheng, Mingjian Ruan, Wei Yu, Xiaoman Li, Weibin Wang, Jiadong Wang
J Clin Invest. 2024 Jan 2; 134(1): e172137. Published online 2024 Jan 2. doi: 10.1172/JCI172137
PMCID:
PMC10760972
AbstractArticlePDF–15M
3.
53bp1 mutation enhances brca1 and bard1 embryonic lethality in C. elegans
Sara Hariri, Qianyan Li, JoAnne Engebrecht
MicroPubl Biol. 2023; 2023: 10.17912/micropub.biology.000934. Published online 2023 Jul 29. doi: 10.17912/micropub.biology.000934
PMCID:
PMC10423319
AbstractArticlePDF–488K
4.
A transcriptional cofactor regulatory network for the C. elegans intestine
Brent B Horowitz, Shivani Nanda, Albertha J M Walhout
G3 (Bethesda) 2023 Jul; 13(7): jkad096. Published online 2023 Apr 29. doi: 10.1093/g3journal/jkad096
PMCID:
PMC10320766
AbstractArticlePDF–1.9M
5.
The DREAM complex functions as conserved master regulator of somatic DNA-repair capacities
Arturo Bujarrabal-Dueso, Georg Sendtner, David H. Meyer, Georgia Chatzinikolaou, Kalliopi Stratigi, George A. Garinis, Björn Schumacher
Nat Struct Mol Biol. 2023; 30(4): 475–488. Published online 2023 Mar 23. doi: 10.1038/s41594-023-00942-8
PMCID:
PMC10113156
AbstractArticlePDF–13M
6.
Conservation of transcriptional regulation by BRCA1 and BARD1 in Caenorhabditis elegans
Ishor Thapa, Russell Vahrenkamp, Samuel R Witus, Caitlin Lightle, Owen Falkenberg, Marlo K Sellin Jeffries, Rachel E Klevit, Mikaela D Stewart
Nucleic Acids Res. 2023 Mar 21; 51(5): 2108–2116. Published online 2022 Oct 17. doi: 10.1093/nar/gkac877
PMCID:
PMC10018340
AbstractArticlePDF–1.3M
7.
Differential requirement for BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in the Caenorhabditis elegans germ line
Qianyan Li, Arshdeep Kaur, Kyoko Okada, Richard J. McKenney, JoAnne Engebrecht
PLoS Genet. 2023 Jan; 19(1): e1010457. Published online 2023 Jan 30. doi: 10.1371/journal.pgen.1010457
PMCID:
PMC9910797
AbstractArticlePDF–3.6M
8.
Inheritance of paternal DNA damage by histone-mediated repair restriction
Siyao Wang, David H. Meyer, Björn Schumacher
Nature. 2023; 613(7943): 365–374. Published online 2022 Dec 21. doi: 10.1038/s41586-022-05544-w
PMCID:
PMC9834056
AbstractArticlePDF–23M
9.
Transcriptomic Analysis Reveals JAK2/MPL-Independent Effects of Calreticulin Mutations in a C. elegans Model
Ana Guijarro-Hernández, Laura Eder-Azanza, Cristina Hurtado, David Navarro-Herrera, Begoña Ezcurra, Francisco Javier Novo, Juan Cabello, José Luis Vizmanos
Cells. 2023 Jan; 12(1): 186. Published online 2023 Jan 2. doi: 10.3390/cells12010186
PMCID:
PMC9818371
AbstractArticlePDF–3.8M
10.
PARG and BRCA1–BARD1 cooperative function regulates DNA repair pathway choice during gametogenesis
Shalini Trivedi, Jitka Blazícková, Nicola Silva
Nucleic Acids Res. 2022 Nov 28; 50(21): 12291–12308. Published online 2022 Dec 8. doi: 10.1093/nar/gkac1153
PMCID:
PMC9757042
AbstractArticlePDF–25M
11.
Helicase Q promotes homology-driven DNA double-strand break repair and prevents tandem duplications
J. A. Kamp, B. B. L. G. Lemmens, R. J. Romeijn, S. C. Changoer, R. van Schendel, M. Tijsterman
Nat Commun. 2021; 12: 7126. Published online 2021 Dec 8. doi: 10.1038/s41467-021-27408-z
PMCID:
PMC8654963
AbstractArticlePDF–1.0M
12.
Analysis of representative mutants for key DNA repair pathways on healthspan in Caenorhabditis elegans
Lucile Marchal, Shruthi Hamsanathan, Roshan Karthikappallil, Suhao Han, Himaly Shinglot, Aditi U. Gurkar
Mech Ageing Dev. Author manuscript; available in PMC 2022 Dec 1.
Published in final edited form as: Mech Ageing Dev. 2021 Dec; 200: 111573. Published online 2021 Sep 22. doi: 10.1016/j.mad.2021.111573
PMCID:
PMC8627479
AbstractArticlePDF–1.2M
13.
Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation
Bettina Meier, Nadezda V. Volkova, Ye Hong, Simone Bertolini, Víctor González-Huici, Tsvetana Petrova, Simon Boulton, Peter J. Campbell, Moritz Gerstung, Anton Gartner
PLoS One. 2021; 16(4): e0250291. Published online 2021 Apr 27. doi: 10.1371/journal.pone.0250291
PMCID:
PMC8078821
AbstractArticlePDF–2.7M
14.
DNA topoisomerase 3 is required for efficient germ cell quality control
Maria Rosaria Dello Stritto, Bernd Bauer, Pierre Barraud, Verena Jantsch
J Cell Biol. 2021 Jun 7; 220(6): e202012057. Published online 2021 Apr 2. doi: 10.1083/jcb.202012057
PMCID:
PMC8025215
AbstractArticlePDF–6.3M
15.
BRCA1–BARD1 Regulates Axon Regeneration in Concert with the Gqα–DAG Signaling Network
Yoshiki Sakai, Hiroshi Hanafusa, Tatsuhiro Shimizu, Strahil I. Pastuhov, Naoki Hisamoto, Kunihiro Matsumoto
J Neurosci. 2021 Mar 31; 41(13): 2842–2853. doi: 10.1523/JNEUROSCI.1806-20.2021
PMCID:
PMC8018897
AbstractArticlePDF–2.4M
16.
Functional characterization of Caenorhabditis elegans cbs-2 gene during meiosis
Pamela Santonicola, Marcello Germoglio, Domenico Scotto d’Abbusco, Adele Adamo
Sci Rep. 2020; 10: 20913. Published online 2020 Dec 1. doi: 10.1038/s41598-020-78006-w
PMCID:
PMC7708620
AbstractArticlePDF–5.0M
17.
Meiotic Double-Strand Break Processing and Crossover Patterning Are Regulated in a Sex-Specific Manner by BRCA1–BARD1 in Caenorhabditis elegans
Qianyan Li, Sara Hariri, JoAnne Engebrecht
Genetics. 2020 Oct; 216(2): 359–379. Published online 2020 Aug 12. doi: 10.1534/genetics.120.303292
PMCID:
PMC7536853
AbstractArticlePDF–2.7M
18.
DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans
Kin Man Suen, Fabian Braukmann, Richard Butler, Dalila Bensaddek, Alper Akay, Chi-Chuan Lin, Dovilė Milonaitytė, Neel Doshi, Alexandra Sapetschnig, Angus Lamond, John Edward Ladbury, Eric Alexander Miska
Nat Commun. 2020; 11: 4242. Published online 2020 Aug 25. doi: 10.1038/s41467-020-18089-1
PMCID:
PMC7447803
AbstractArticlePDF–2.3M
19.
BRCA1-associated structural variations are a consequence of polymerase theta-mediated end-joining
J. A. Kamp, R. van Schendel, I. W. Dilweg, M. Tijsterman
Nat Commun. 2020; 11: 3615. Published online 2020 Jul 17. doi: 10.1038/s41467-020-17455-3
PMCID:
PMC7368036
AbstractArticlePDF–885K
20.
In vivo analysis of FANCD2 recruitment at meiotic DNA breaks in Caenorhabditis elegans
Marcello Germoglio, Anna Valenti, Ines Gallo, Chiara Forenza, Pamela Santonicola, Nicola Silva, Adele Adamo
Sci Rep. 2020; 10: 103. Published online 2020 Jan 9. doi: 10.1038/s41598-019-57096-1
PMCID:
PMC6952437
AbstractArticlePDF–4.7M

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