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Select item 110722721.

EAT-2 attenuates C. elegans development via metabolic remodeling in a chemically defined food environment

Xuwen Cao, Yusu Xie, Hanwen Yang, Peiqi Sun, Beining Xue, L. Rene Garcia, Liusuo Zhang

Cell Mol Life Sci. 2023 Aug; 80(8): 205. Published online 2023 Jul 14. doi: 10.1007/s00018-023-04849-x

PMCID:: PMC11072272

Abstract Article PDF–4.4M

Select item 108282692.

In-vivo screening implicates endoribonuclease Regnase-1 in modulating senescence-associated lysosomal changes

Richard Venz, Anita Goyala, Abel Soto-Gamez, Tugce Yenice, Marco Demaria, Collin Y. Ewald

GeroScience. 2024 Apr; 46(2): 1499–1514. Published online 2023 Aug 29. doi: 10.1007/s11357-023-00909-z

PMCID:: PMC10828269

Abstract Article PDF–3.0M

Select item 102562353.

A worm’s life: AMPK links muscle mitochondrial dynamics to physical fitness and healthy aging in Caenorhabditis elegans

Vihang A. Narkar

J Cardiovasc Aging. Author manuscript; available in PMC 2023 Jun 9.

Published in final edited form as: J Cardiovasc Aging. 2023; 3(3): 25. Published online 2023 May 4. doi: 10.20517/jca.2023.14

PMCID:: PMC10256235

Article PDF–237K

Select item 102364454.

Increased Alcohol Dehydrogenase 1 activity promotes longevity

Abbas Ghaddar, Vinod K. Mony, Swarup Mishra, Samuel Berhanu, James C. Johnson, Elisa Enriquez-Hesles, Emma Harrison, Aaroh Patel, Mary Kate Horak, Jeffrey S. Smith, Eyleen J. O’Rourke

Curr Biol. Author manuscript; available in PMC 2024 Mar 27.

Published in final edited form as: Curr Biol. 2023 Mar 27; 33(6): 1036–1046.e6. Published online 2023 Feb 17. doi: 10.1016/j.cub.2023.01.059

PMCID:: PMC10236445

Abstract Article PDF–1.3M

Select item 102291325.

Bacterial diet affects the age-dependent decline of associative learning in Caenorhabditis elegans

Satoshi Higurashi, Sachio Tsukada, Binta Maria Aleogho, Joo Hyun Park, Yana Al-Hebri, Masaru Tanaka, Shunji Nakano, Ikue Mori, Kentaro Noma

eLife. 2023; 12: e81418. Published online 2023 May 30. doi: 10.7554/eLife.81418

PMCID:: PMC10229132

Abstract Article PDF–1.0M

Select item 101542366.

Decreased spliceosome fidelity and egl-8 intron retention inhibit mTORC1 signaling to promote longevity

Wenming Huang, Chun Kew, Stephanie de Alcantara Fernandes, Anna Löhrke, Lynn Han, Constantinos Demetriades, Adam Antebi

Nat Aging. 2022; 2(9): 796–808. Published online 2022 Sep 19. doi: 10.1038/s43587-022-00275-z

PMCID:: PMC10154236

Abstract Article PDF–17M

Select item 100865217.

The conserved microRNA‐229 family controls low‐insulin signaling and dietary restriction induced longevity through interactions with SKN‐1/NRF2

Latika Matai, Thalyana Stathis, Jonathan D. Lee, Christine Parsons, Tanvi Saxena, Kovi Shlomchik, Frank J. Slack

Aging Cell. 2023 Apr; 22(4): e13785. Published online 2023 Feb 7. doi: 10.1111/acel.13785

PMCID:: PMC10086521

Abstract Article PDF–5.0M

Select item 100695238.

Gold Nanoparticles Reduce Food Sensation in Caenorhabditis elegans via the Voltage-Gated Channel EGL-19

Meimei Wang, Zhenzhen Zhang, Ning Sun, Baolin Yang, Jihao Mo, Daping Wang, Mingqin Su, Jian Hu, Miaomiao Wang, Lei Wang

Int J Nanomedicine. 2023; 18: 1659–1676. Published online 2023 Mar 30. doi: 10.2147/IJN.S394666

Correction in:: Int J Nanomedicine. 2023; 18: 2797–2798.

PMCID:: PMC10069523

Abstract Article PDF–11M

Select item 99703129.

The lipidomes of C. elegans with mutations in asm-3/acid sphingomyelinase and hyl-2/ceramide synthase show distinct lipid profiles during aging

Trisha A. Staab, Grace McIntyre, Lu Wang, Joycelyn Radeny, Lisa Bettcher, Melissa Guillen, Margaret P. Peck, Azia P. Kalil, Samantha P. Bromley, Daniel Raftery, Jason P. Chan

Aging (Albany NY) 2023 Feb 14; 15(3): 650–674. Published online 2023 Feb 13. doi: 10.18632/aging.204515

PMCID:: PMC9970312

Abstract Article PDF–2.0M

Select item 992627810.

Exercise preserves physical fitness during aging through AMPK and mitochondrial dynamics

Juliane Cruz Campos, Luiz Henrique Marchesi Bozi, Barbara Krum, Luiz Roberto Grassmann Bechara, Nikolas Dresch Ferreira, Gabriel Santos Arini, Rudá Prestes Albuquerque, Annika Traa, Takafumi Ogawa, Alexander M. van der Bliek, Afshin Beheshti, Edward T. Chouchani, Jeremy M. Van Raamsdonk, T. Keith Blackwell, Julio Cesar Batista Ferreira

Proc Natl Acad Sci U S A. 2023 Jan 10; 120(2): e2204750120. Published online 2023 Jan 3. doi: 10.1073/pnas.2204750120

PMCID:: PMC9926278

Abstract Article PDF–5.4M

Select item 985507411.

Genistein Promotes Anti-Heat Stress and Antioxidant Effects via the Coordinated Regulation of IIS, HSP, MAPK, DR, and Mitochondrial Pathways in Caenorhabditis elegans

Sai-Ya Zhang, Zi-Chen Qin, Yi-Yang Sun, Yu-Si Chen, Wen-Bo Chen, Hong-Gang Wang, Di An, Dan Sun, Yan-Qiang Liu

Antioxidants (Basel) 2023 Jan; 12(1): 125. Published online 2023 Jan 4. doi: 10.3390/antiox12010125

PMCID:: PMC9855074

Abstract Article PDF–2.2M

Select item 982067012.

Isocitrate Dehydrogenase Alpha-1 Modulates Lifespan and Oxidative Stress Tolerance in Caenorhabditis elegans

Zhi-Han Lin, Shun-Ya Chang, Wen-Chi Shen, Yen-Hung Lin, Chiu-Lun Shen, Sin-Bo Liao, Yu-Chun Liu, Chang-Shi Chen, Tsui-Ting Ching, Horng-Dar Wang

Int J Mol Sci. 2023 Jan; 24(1): 612. Published online 2022 Dec 29. doi: 10.3390/ijms24010612

PMCID:: PMC9820670

Abstract Article PDF–2.9M

Select item 980994813.

SAMS-1 coordinates HLH-30/TFEB and PHA-4/FOXA activities through histone methylation to mediate dietary restriction-induced autophagy and longevity

Chiao-Yin Lim, Huan-Ting Lin, Caroline Kumsta, Tzu-Chiao Lu, Feng-Yung Wang, Yun-Hsuan Kang, Malene Hansen, Tsui-Ting Ching, Ao-Lin Hsu

Autophagy. 2023; 19(1): 224–240. Published online 2022 May 3. doi: 10.1080/15548627.2022.2068267

PMCID:: PMC9809948

Abstract Article PDF–4.7M

Select item 980861714.

Systematic transcriptome analysis associated with physiological and chronological aging in Caenorhabditis elegans

Seokjin Ham, Sieun S. Kim, Sangsoon Park, Eun Ji E. Kim, Sujeong Kwon, Hae-Eun H. Park, Yoonji Jung, Seung-Jae V. Lee

Genome Res. 2022 Nov-Dec; 32(11-12): 2003–2014. doi: 10.1101/gr.276515.121

PMCID:: PMC9808617

Abstract Article PDF–2.2M

Select item 959867015.

Anti-Oxidant and Anti-Aging Effects of Phlorizin Are Mediated by DAF-16-Induced Stress Response and Autophagy in Caenorhabditis elegans

Suhyeon Park, Sang-Kyu Park

Antioxidants (Basel) 2022 Oct; 11(10): 1996. Published online 2022 Oct 8. doi: 10.3390/antiox11101996

PMCID:: PMC9598670

Abstract Article PDF–3.7M

Select item 951484916.

H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans

Meng Huang, Minjie Hong, Xinhao Hou, Chengming Zhu, Di Chen, Xiangyang Chen, Shouhong Guang, Xuezhu Feng

eLife. 2022; 11: e74812. Published online 2022 Sep 20. doi: 10.7554/eLife.74812

PMCID:: PMC9514849

Abstract Article PDF–2.1M

Select item 901634617.

Ageing induces tissue‐specific transcriptomic changes in Caenorhabditis elegans

Xueqing Wang, Quanlong Jiang, Yuanyuan Song, Zhidong He, Hongdao Zhang, Mengjiao Song, Xiaona Zhang, Yumin Dai, Oezlem Karalay, Christoph Dieterich, Adam Antebi, Ligang Wu, Jing‐Dong J Han, Yidong Shen

EMBO J. 2022 Apr; 41(8): e109633. Published online 2022 Mar 7. doi: 10.15252/embj.2021109633

PMCID:: PMC9016346

Abstract Article PDF–4.9M

Select item 894235918.

Small RNAs couple embryonic developmental programs to gut microbes

Hayao Ohno, Zhirong Bao

Sci Adv. 2022 Mar; 8(12): eabl7663. Published online 2022 Mar 23. doi: 10.1126/sciadv.abl7663

PMCID:: PMC8942359

Abstract Article PDF–4.7M

Select item 892468919.

Longevity interventions temporally scale healthspan in Caenorhabditis elegans

Cyril Statzer, Peter Reichert, Jürg Dual, Collin Y. Ewald

iScience. 2022 Mar 18; 25(3): 103983. Published online 2022 Feb 24. doi: 10.1016/j.isci.2022.103983

PMCID:: PMC8924689

Abstract Article PDF–4.2M

Select item 885722620.

ATF-4 and hydrogen sulfide signalling mediate longevity in response to inhibition of translation or mTORC1

Cyril Statzer, Jin Meng, Richard Venz, Monet Bland, Stacey Robida-Stubbs, Krina Patel, Dunja Petrovic, Raffaella Emsley, Pengpeng Liu, Ianessa Morantte, Cole Haynes, William B. Mair, Alban Longchamp, Milos R. Filipovic, T. Keith Blackwell, Collin Y. Ewald

Nat Commun. 2022; 13: 967. Published online 2022 Feb 18. doi: 10.1038/s41467-022-28599-9